Alice K. Jacobs, MD
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Saint Louis University

Alice K. Jacobs, MD, FACC, FAHA, MSCAI is a Professor of Medicine at Boston University School of Medicine and served as the Director of the Cardiac Catheterization Laboratories and Interventional Cardiology for 20 years until 2011. She is currently Vice Chair for Clinical Affairs in the Department of Medicine at Boston University Medical Center and maintains an active clinical practice. Dr. Jacobs has led the American Heart Association’s Mission: Lifeline, a community-based, national initiative to develop systems of care for ST-segment elevation myocardial infarction (STEMI) patients and to increase the number of patients with timely access to primary percutaneous coronary intervention. Mission: Lifeline has now expanded to include Out-of-Hospital Cardiac Arrest and Stroke systems of care. Dr. Jacobs served as president of the American Heart Association in 2004-05 and as president of the Association of University Cardiologists in 2011. She is a past chair of the ACC/AHA Task Force on Practice Guidelines. During her tenure, the guidelines process and methodology evolved to include formal systematic evidence reviews, inclusion of patient representatives and lay members on guideline committees, incorporation of an Evidence Grading Tool, and further enhancements to the Class of Recommendation/Level of Evidence schema. Dr. Jacobs is a prior member of CMS MEDCAC and the IOM Committee on Social Security Cardiovascular Disability. Currently, she is the immediate past-chair of the American Board of Internal Medicine Interventional Cardiology Self-Assessment Test Committee, a member of NHLBI Cardiothoracic Surgical Network Protocol Review Committee and a member of the New York State Cardiac Advisory Committee. Her major research interest is in coronary revascularization strategies and sex-based difference in ischemic heart disease.

Expertise includes: Interventional Cardiology; Coronary revascularization; Sex-based differences in cardiovascular disease.

Boston University
Whitaker Cardiovascular Institute

Boston University
Evans Center for Interdisciplinary Biomedical Research

A Clinical Evaluation of Absorb BVS, the Everolimus Eluting Bioresorbable Vascular Scaffold in the Treatment...
08/22/2013 - 06/30/2021 (PI)
Abbott Laboratories

A prospective, multi-center, randomized, double-blind trial to assess the effectiveness and safety of 12 versus 30 months of dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous c
05/01/2010 - 04/30/2015 (PI)
Harvard Clinical Research Institute

Gravitas: Gauging Responsivness with a Verify Now Assay-Impact on Thrombsis and Safety
10/01/2008 - 09/30/2012 (PI)

Xience V Everolimus Eluting Coronary Stent System Post-Approval Study (EECSS)
09/01/2008 - 05/31/2012 (PI)
Abbott Laboratories

Tilarginine Acetate Injection in a Randomized International Study in Unstable AMI Patients / Cardiogenic Shock
07/01/2005 - 06/30/2007 (PI)

D.E.S. Cover Registry
04/13/2005 - 04/12/2007 (PI)
Cordis Corporation

The GUARD Trial Saphenous Vein Graft Intervention Using AngioGuard for Reduction of Distal Embolization
11/29/2000 - 12/31/2005 (PI)
Cordis Corporation

Clopidogrel for Reduction of Events During Observation (CREDO)
08/25/2000 - 08/31/2001 (PI)
Sanofi Pharmaceuticals Inc (from Cleveland Clinic Foundation) Bristol-Myers Squibb

XaNADU PCI Pilot Trial
01/22/2001 - 05/31/2001 (PI)
Duke University

Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study
06/01/2015 - 05/31/2018 (PI)
Duke University Astrazeneca Pharmace

SILVER-AMI : Risk Stratification in Older Persons with Acute Myocardial Infarction
06/01/2013 - 05/31/2018 (PI)
Yale University NIH-NHLBI

08/30/2006 - 06/30/2014 (PI)
Harvard Clinical Research Institute DPH

VIRGO study
04/01/2009 - 05/01/2014 (PI)
Yale University NIH-NHLBI
R01 HL081153

Occluded Artery Trial (OAT)
02/01/2001 - 12/31/2010 (PI)
New York University DHHS
U01 HL62509

Bari 2 Diabetes (BARI 2D) Data Coordinating Center
01/01/2001 - 09/30/2010 (PI)
University of Pittsburgh DHHS
5 U01 HL61744-03

FREEDOM (Future Revascularization Evaluation in patients with Diabetes mellitus: Optimal management
06/22/2006 - 12/31/2007 (PI)
Mount Sinai Medical Center NIH-NHLBI
1 R01 HL 071988-01A1

SHOCK II Phase 2 Trial
11/01/2003 - 10/30/2005 (PI)
Arginox Pharmaceuticals NIH-NHLBI

Mechanisms Of Pro Thrombosis I
07/01/2001 - 06/30/2005 (PI)
University of Vermont NIH-NHLBI


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Hannan EL, Wu YF, Cozzens K, Tamis-Holland J, Ling FSK, Jacobs AK, Venditti FJ, Berger PB, Walford G, King Iii SB. Hybrid coronary revascularization vs. percutaneous coronary interventions for multivessel coronary artery disease. J Geriatr Cardiol. 2021 Mar 28; 18(3):159-167. PMID: 33907545; PMCID: PMC8047190; DOI: 10.11909/j.issn.1671-5411.2021.03.003;
  2. Hannan EL, Wu Y, Cozzens K, Friedrich M, Tamis-Holland J, Jacobs AK, Ling FSK, King SB, Venditti FJ, Walford G, Berger PB, Kirtane AJ, Kamran M. Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Before and During COVID in New York. Am J Cardiol. 2021 03 01; 142:25-34. PMID: 33301770; PMCID: PMC7723434; DOI: 10.1016/j.amjcard.2020.11.033;
  3. Shahandeh N, Dai X, Jaski B, Dave R, Jacobs A, Denktas A, Levine G, Markovic D, Smith SC, Press MC. Mortality differences among patients with in-hospital ST-elevation myocardial infarction. Clin Cardiol. 2020 Dec; 43(12):1555-1561. PMID: 33159461; PMCID: PMC7724232; DOI: 10.1002/clc.23480;
  4. Mendirichaga R, Jacobs AK. Sex Differences in Ischemic Heart Disease-the Paradox Persists. JAMA Cardiol. 2020 07 01; 5(7):754-756. PMID: 32227138
  5. Al-Lamee R, Jacobs AK. ISCHEMIA Trial: Was It Worth the Wait? Circulation. 2020 Aug 11; 142(6):517-519. PMID: 32316761
  6. Kontos MC, Gunderson MR, Zegre-Hemsey JK, Lange DC, French WJ, Henry TD, McCarthy JJ, Corbett C, Jacobs AK, Jollis JG, Manoukian SV, Suter RE, Travis DT, Garvey JL. Prehospital Activation of Hospital Resources (PreAct) ST-Segment-Elevation Myocardial Infarction (STEMI): A Standardized Approach to Prehospital Activation and Direct to the Catheterization Laboratory for STEMI Recommendations From the American Heart Association's Mission: Lifeline Program. J Am Heart Assoc. 2020 01 21; 9(2):e011963. PMID: 31957530; PMCID: PMC7033830; DOI: 10.1161/JAHA.119.011963;
  7. Hannan EL, Zhong Y, Ling FSK, Tamis-Holland J, Berger PB, Jacobs AK, Walford G, Venditti FJ, King SB. Assessment of repeat target lesion percutaneous coronary intervention as a quality measure for public reporting and general quality assessment for PCIs. Catheter Cardiovasc Interv. 2020 10 01; 96(4):731-740. PMID: 31642597
  8. Rymer JA, Kaltenbach LA, Kochar A, Hess CN, Gilchrist IC, Messenger JC, Harrington RA, Jolly SS, Jacobs AK, Abbott JD, Wojdyla DM, Krucoff MW, Rao SV. Comparison of Rates of Bleeding and Vascular Complications Before, During, and After Trial Enrollment in the SAFE-PCI Trial for Women. Circ Cardiovasc Interv. 2019 05; 12(5):e007086. PMID: 31014090
  9. Hannan EL, Wu Y, Tamis-Holland J, Jacobs AK, Berger PB, Ling FSK, Walford G, Venditti FJ, King SB. Sex differences in the treatment and outcomes of patients hospitalized with ST-elevation myocardial infarction. Catheter Cardiovasc Interv. 2020 02; 95(2):196-204. PMID: 31012227
  10. Pande AN, Jacobs AK. Reperfusion and Time to Presentation in Women: Too Little Too Late. J Am Heart Assoc. 2019 02 19; 8(4):e011835.View Related Profiles. PMID: 30767600; PMCID: PMC6405660; DOI: 10.1161/JAHA.118.011835;
Showing 10 of 405 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 396 publications over 40 distinct years, with a maximum of 28 publications in 2006

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

acute coronary syndromes
angioplasty, percutaneous transluminal
coronary artery disease
Interventional cardiology; Women and heart disease
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88 E. Newton St Newton Pavilion
Boston MA 02118
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