Helen M. Hollingsworth, MD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, University of Rochester School of Medicine and Dentistry



I spend the majority of my time at UpToDate, which is an online clinical resource for physicians. In my work as a Deputy Editor, I collaborate with outside authors and editors to research and evaluate the medical literature for pulmonary medicine to provide evidence-based, point-of-care guidance for the practicing physician. While the main goal of UpToDate is to guide clinical decision-making, UpToDate also serves as a major resource for Continuing Medical Education, Maintenance-of-Certification, and Patient Education. Previously, I developed the curriculum for the Allergy & Immunology fellowship program at Boston Medical Center and served as the training program director for many years. In addition, I participated in a number of multicenter trials of medications for asthma, COPD, and idiopathic pulmonary fibrosis.

2007-2017 Castle Connolly: Top Doctors
2004 Boston Medical Center: Robert Dawson Evans Department of Medicine Teaching Award
2004-2017 Boston Magazine: Best Doctors


An Open-Label Study of the Safety of Subcutaneous Recombinant Interferon gamma-1b (IFN-y 1b) in Patients with Idiopathic Pulmonary Fibrosis
01/01/2004 - 12/31/2009 (PI)
InterMune, Inc.

A Randomized, Double-Blind, Placebo-Controlled, Phase 3, Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis PIPF-004.
08/21/2006 - 10/31/2008 (PI)
InterMune, Inc.

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of ug Subcutaneous Interferon gamma-1b in Patients with Idiopathic Pulmonary Fibrosis GIPF-007
10/21/2003 - 10/20/2005 (PI)
InterMune, Inc.


A Randomized, Double-Blind, Parallel Group, 52 Week Study to Compare the Effect of Fluticasone Propionate/Salmeterol DISKUS Combination Product 250/50mcg BID with Salmeterol DISKUS 50mcg BID on t
09/30/2004 - 09/29/2005 (PI)
GlaxoSmithKline, Inc.


Protocol SB 207499/180
09/01/2003 - 09/01/2005 (PI)
GlaxoSmithKline, Inc.

Inspire 01-312 A Double Blind, Placebo Controlled, Parallel Group Study of Uridine 5’-Triphosphate (UTP)
07/15/2003 - 12/31/2004 (PI)
Inspire Pharmaceuticals Inc

An Open Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon Gamma-ibin Patients with Idiopathic Pulmonary Fibrosis
10/01/2002 - 12/31/2003 (PI)
InterMune, Inc.

A Randomized, Double-Blind, Placebo Controlled, Phase 2/3 Study of the Safety and Efficacy of Subcutaneous Recombinant ACTIMMUNE in Patients with Idiopathic Pulmonary Fibrosis
07/01/2000 - 12/31/2003 (PI)
InterMune, Inc.

Start-Inhaled Steroid Treatment as Regular Therapy in Early Asthma
04/01/1997 - 12/31/2003 (PI)
ASTRA USA Inc

A 3-Month, Multi-center, Multinational, Double-blind, Group Comparative Study to Investigate the Effects of AR C68397AA via MDI Compared with Placebo in Adult Patients with Chronic Obstructive Pulmonary Disease (COPD)
05/30/2000 - 06/30/2001 (PI)
AstraZeneca

Showing 10 of 12 results. Show All Results



Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Hollingsworth HM, O'Connor GT. Asthma-Here Today, Gone Tomorrow? JAMA. 2017 01 17; 317(3):262-263.View Related Profiles. PMID: 28114530; DOI: 10.1001/jama.2016.19676;.
  2. Saketkoo LA, Mittoo S, Frankel S, LeSage D, Sarver C, Phillips K, Strand V, Matteson EL. Reconciling healthcare professional and patient perspectives in the development of disease activity and response criteria in connective tissue disease-related interstitial lung diseases. J Rheumatol. 2014 Apr; 41(4):792-8. PMID: 24488412; PMCID: PMC4369780; DOI: 10.3899/jrheum.131251;.
  3. Hollingsworth HM, Parada, NA. Manual of Intensive Care Medicine. Anaphylaxis. Lippincott Williams & Wilkins. 2014; 1119-1126.
  4. Saketkoo LA, Mittoo S, Huscher D, Khanna D, Dellaripa PF, Distler O, Flaherty KR, Frankel S, Oddis CV, Denton CP, Fischer A, Kowal-Bielecka OM, LeSage D, Merkel PA, Phillips K, Pittrow D, Swigris J, Antoniou K, Baughman RP, Castelino FV, Christmann RB, Christopher-Stine L, Collard HR, Cottin V, Danoff S, Highland KB, Hummers L, Shah AA, Kim DS, Lynch DA, Miller FW, Proudman SM, Richeldi L, Ryu JH, Sandorfi N, Sarver C, Wells AU, Strand V, Matteson EL, Brown KK, Seibold JR. Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials. Thorax. 2014 May; 69(5):428-36.View Related Profiles. PMID: 24368713; PMCID: PMC3995282; DOI: 10.1136/thoraxjnl-2013-204202;.
  5. Little FF, Hollingsworth HM. Anaphylaxis. Intensive Care Medicine, Irwin R, Rippe J, eds. Lippincott Wilkins & Williams. 2012.
  6. Hollingsworth HM, Pratter MR, Irvin RS. Extrapulmonary Causes of Respiratory Failure. Intensive Care Medicine, Irwin R, Rippe J, eds. Lippincott Wilkins & Williams. 2012.
  7. Reardon CC, Hollingsworth HM. Acute Respiratory Failure in Pregnancy. Intensive Care Medicine, Irwin R, Rippe J, eds. Lippincott Wilkins & Williams. 2012.
  8. Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, King TE, Lancaster L, Sahn SA, Szwarcberg J, Valeyre D, du Bois RM. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet. 2011 May 21; 377(9779):1760-9. PMID: 21571362; DOI: 10.1016/S0140-6736(11)60405-4;.
  9. King TE, Albera C, Bradford WZ, Costabel U, Hormel P, Lancaster L, Noble PW, Sahn SA, Szwarcberg J, Thomeer M, Valeyre D, du Bois RM. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial. Lancet. 2009 Jul 18; 374(9685):222-8. PMID: 19570573; DOI: 10.1016/S0140-6736(09)60551-1;.
  10. Wexler P, Hollingsworth H. Chronic rhinosinusitis. Challenging Cases in Allergy and Immunology, M Mahmoudi, ed. Springer. 2009.
Showing 10 of 65 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 62 publications over 24 distinct years, with a maximum of 6 publications in 1991 and 2008

YearPublications
19841
19853
19872
19892
19916
19923
19934
19942
19951
19964
19974
19993
20003
20011
20033
20051
20062
20086
20093
20111
20123
20131
20142
20171
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Asthma
Idiopathic pulmonary fibrosis
Interstitial lung disease

As a training program director for Allergy & Immunology and a faculty member in Pulmonary, Allergy, Critical Care, and Sleep Medicine, I have mentored over 35 Allergy-Immunology and Pulmonary-Critical Care trainees as well as other residents and students, in areas of career development, publications, thesis preparation, and career-life balance. I received the Robert Dawson Evans Department of Medicine Teaching Award in 2004, and throughout my career I have enjoyed teaching and mentoring junior faculty, fellows, residents, and medical students and helping them to clarify and achieve their aspirations.

Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Education Mentor
  • Project Mentor
  • Work / Life Integration Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')


72 E. Concord St Housman (R)
Boston MA 02118
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