Keywords
Last Name

Romy Christmann, MD, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionRheumatology (Arthritis)
Address75 E. Newton St Evans Building
Boston MA 02118
Phone(617) 638-4309
ORCID ORCID Icon0000-0003-1015-5121
 Research Expertise & Professional Interests
I have a special interest in Systemic Sclerosis (SSc). Our lab is a leader in development/validation of biomarkers for skin fibrosis, pulmonary arterial hypertension and lung fibrosis related to SSc. My main focus of translational research is the involvement of TSLP in the development of SSc and as one of the master regulators of a pro-fibrotic environment.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Christmann RB. Another Piece in the Fibrotic Puzzle: TSLP as a Novel Ligand for Fibrocyte Activation. J Invest Dermatol. 2016 Feb; 136(2):360-2. PMID: 26802232.
    View in: PubMed
  2. Christmann RB, Sampaio-Barros P, Stifano G, Borges CL, de Carvalho CR, Kairalla R, Parra ER, Spira A, Simms R, Capellozzi VL, Lafyatis R. Association of Interferon- and transforming growth factor ß-regulated genes and macrophage activation with systemic sclerosis-related progressive lung fibrosis. Arthritis Rheumatol. 2014 Mar; 66(3):714-25. PMID: 24574232.
    View in: PubMed
  3. Saketkoo LA, Mittoo S, Huscher D, Khanna D, Dellaripa PF, Distler O, Flaherty KR, Frankel S, Oddis CV, Denton CP, Fischer A, Kowal-Bielecka OM, LeSage D, Merkel PA, Phillips K, Pittrow D, Swigris J, Antoniou K, Baughman RP, Castelino FV, Christmann RB, Christopher-Stine L, Collard HR, Cottin V, Danoff S, Highland KB, Hummers L, Shah AA, Kim DS, Lynch DA, Miller FW, Proudman SM, Richeldi L, Ryu JH, Sandorfi N, Sarver C, Wells AU, Strand V, Matteson EL, Brown KK, Seibold JR. Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials. Thorax. 2014 May; 69(5):428-36. PMID: 24368713.
    View in: PubMed
  4. van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JP, de Graaf J, den Heijer M, Kallenberg CG, Bijl M, Loof A, van den Berg WB, Joosten LA, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PL, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TR. Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med. 2014 Jan 30; 370(5):433-43. PMID: 24350901.
    View in: PubMed
  5. Mathes AL, Christmann RB, Stifano G, Affandi AJ, Radstake TR, Farina GA, Padilla C, McLaughlin S, Lafyatis R. Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin. Ann Rheum Dis. 2014 Oct; 73(10):1864-72. PMID: 23873879.
    View in: PubMed
  6. Lenna S, Farina AG, Martyanov V, Christmann RB, Wood TA, Farber HW, Scorza R, Whitfield ML, Lafyatis R, Trojanowska M. Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension. Arthritis Rheum. 2013 May; 65(5):1357-66. PMID: 23400395.
    View in: PubMed
  7. Christmann RB, Mathes A, Affandi AJ, Padilla C, Nazari B, Bujor AM, Stifano G, Lafyatis R. Thymic stromal lymphopoietin is up-regulated in the skin of patients with systemic sclerosis and induces profibrotic genes and intracellular signaling that overlap with those induced by interleukin-13 and transforming growth factor ß. Arthritis Rheum. 2013 May; 65(5):1335-46. PMID: 23335246.
    View in: PubMed
  8. Bujor AM, Haines P, Padilla C, Christmann RB, Junie M, Sampaio-Barros PD, Lafyatis R, Trojanowska M. Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1. Int J Mol Med. 2012 Dec; 30(6):1473-80. PMID: 23041765.
    View in: PubMed
  9. Martin P, Teodoro WR, Velosa AP, de Morais J, Carrasco S, Christmann RB, Goldenstein-Schainberg C, Parra ER, Katayama ML, Sotto MN, Capelozzi VL, Yoshinari NH. Abnormal collagen V deposition in dermis correlates with skin thickening and disease activity in systemic sclerosis. Autoimmun Rev. 2012 Sep; 11(11):827-35. PMID: 22406224.
    View in: PubMed
  10. Monteiro TA, Christmann RB, Bonfá E, Bento RF, Novalo-Goto ES, Vasconcelos LG. Hearing loss in diffuse cutaneous systemic scleroderma. Scand J Rheumatol. 2011 Nov; 40(6):467-71. PMID: 21916804.
    View in: PubMed
  11. Christmann RB, Hayes E, Pendergrass S, Padilla C, Farina G, Affandi AJ, Whitfield ML, Farber HW, Lafyatis R. Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension. Arthritis Rheum. 2011 Jun; 63(6):1718-28. PMID: 21425123.
    View in: PubMed
  12. Pinto AL, Oliveira NC, Gualano B, Christmann RB, Painelli VS, Artioli GG, Prado DM, Lima FR. Efficacy and safety of concurrent training in systemic sclerosis. J Strength Cond Res. 2011 May; 25(5):1423-8. PMID: 21116202.
    View in: PubMed
  13. Christmann RB, Lafyatis R. The cytokine language of monocytes and macrophages in systemic sclerosis. Arthritis Res Ther. 2010; 12(5):146. PMID: 21067557.
    View in: PubMed
  14. Domiciano DS, Bonfá E, Borges CT, Kairalla RA, Capelozzi VL, Parra E, Christmann RB. A long-term prospective randomized controlled study of non-specific interstitial pneumonia (NSIP) treatment in scleroderma. Clin Rheumatol. 2011 Feb; 30(2):223-9. PMID: 20544245.
    View in: PubMed
  15. Christmann RB, Wells AU, Capelozzi VL, Silver RM. Gastroesophageal reflux incites interstitial lung disease in systemic sclerosis: clinical, radiologic, histopathologic, and treatment evidence. Semin Arthritis Rheum. 2010 Dec; 40(3):241-9. PMID: 20494406.
    View in: PubMed
  16. Ferreira EL, Christmann RB, Borba EF, Borges CT, Siqueira JT, Bonfa E. Mandibular function is severely impaired in systemic sclerosis patients. J Orofac Pain. 2010; 24(2):197-202. PMID: 20401358.
    View in: PubMed
  17. Borba EF, Guedes LK, Christmann RB, Figueiredo CP, Gonçalves CR, Bonfá E. Mycophenolate mofetil is effective in reducing lupus glomerulonephritis proteinuria. Rheumatol Int. 2006 Oct; 26(12):1078-83. PMID: 16736162.
    View in: PubMed
  18. Filho JS, Soares MF, Wal R, Christmann RB, Liu CB, Schmitt FC. Fine-needle aspiration cytology of pulmonary rheumatoid nodule: case report and review of the major cytologic features. Diagn Cytopathol. 2002 Mar; 26(3):150-3. PMID: 11892018.
    View in: PubMed
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