Allen A. Mitchell, MD
Professor
Boston University School of Public Health
Dept of Epidemiology

MD, Tufts University School of Medicine



Allen A. Mitchell is Professor of Public Health (Epidemiology) and Professor of Pediatrics at the Boston University Schools of Public Health and Medicine. He obtained his BA degree from Washington University in St. Louis in 1966 and his M.D. from Tufts University School of Medicine in Boston in 1970.

After pediatric residency training at the Boston Floating Hospital for Infants and Children (Tufts-New England Medical Center), he joined the Boston Collaborative Drug Surveillance Program where, among other activities, he worked with Drs. Slone, Shapiro, and Heinonen in the analysis of Collaborative Perinatal Project data on birth defects and drugs in pregnancy.

In 1973-75 he was a fellow in pediatric clinical pharmacology at Children's Hospital in Boston (jointly with the Center for the Evaluation of Clinical Procedures at the Harvard School of Public Health), during which time he established the Pediatric Drug Surveillance ("PeDS") Program, an intensive drug surveillance effort focused on the frequency of medication use and adverse effects among hospitalized children. In 1975 he joined Drs. Slone and Shapiro at the newly-created Drug Epidemiology Unit (now Slone Epidemiology Center--SEC) at Boston University, where he continued to direct the PeDS Program.

Following his interest in both pharmacoepidemiology and birth defects, Dr. Mitchell in 1975 applied the concept of case-control surveillance to the study of teratogenesis, and initiated the SEC Birth Defects Study (BDS) which continues to this time, having collected data on prenatal exposures for over 36,000 malformed infants (and controls) identified at over 90 hospitals and state birth defects registries in the regions surrounding Boston, Philadelphia, Toronto, and San Diego. The BDS is now one of two data collection components collaborating with the American Academy of Allergy, Asthma, and Immunology in a national systematic surveillance effort (Vaccines and Medication in Pregnancy Safety Surveillance—“VAMPSS”) designed to evaluate the risks and safety of the wide range of medications taken by pregnant women. Dr. Mitchell also designed and directed a practitioner-based trial of 84,000 children to assess the safety of pediatric ibuprofen, a network that continues to conduct clinically-relevant office-based research, directed epidemiologic efforts to evaluate pregnancy prevention efforts as part of risk management programs associated with isotretinoin (Accutane and others) and thalidomide (Thalomid), and designed the Slone Survey.

Dr. Mitchell is the author of numerous publications in the fields of pediatric and birth defects pharmacoepidemiology and serves on many editorial boards and advisory committees.

Professor
Boston University School of Medicine
Pediatrics
General Pediatrics



Exploring Modifiable Factors for Folic Acid Resistant Spina Bifida
09/01/2015 - 08/31/2018 (Co-PI)
PI: Martha Werler, DSc
HHS/CDC/National Center for Birth Defect
5U01DD001184-02

Massachusetts Center for Birth Defects Research and Prevention
07/01/2014 - 06/30/2018 (PI)
Comm. of Mass./Department of Public Heal HHS CDC
U01DD001037

Analysis of the Association between Infections, Vaccinations, and Medications during Pregnancy and Possible Birth Defects Outcomes, and Creation of an Archived Database
09/23/2016 - 03/22/2018 (PI)
HHS/National Vaccine Program Office


Postmarking Surveillance of Afluria Influenza Vaccine Safety in Pregnancy
08/01/2013 - 07/31/2017 (PI)
American Academy of Allergy, Asthma, and


Protocol Development for Pregnancy Surveillance for Mepolizumab (VAMPSS)
01/11/2016 - 01/10/2017 (PI)
Educational Research Trust (AAAAI) GlaxoSmithKline, Inc


SPECIFIC BIRTH DEFECTS AND ASTHMA MEDICATIONS IN PREGNANCY: DEMONSTRATION PROJECT
09/30/2009 - 07/31/2015 (PI)
HHS/Agency for Healthcare Research and Q
5R18HS018463-05

Case Control Safety Surveillance Study of Influenza in Pregnant Women and their Infants
07/07/2010 - 07/06/2015 (PI)
HHS/PHS (Public Health Contracts) DHHS


Hirschsprung Disease, Birth Defects and Intestinal Motility Disorders
07/01/2014 - 06/30/2015 (PI)
The Children's Hospital of Philadelphia Burroughs Wellcome


Postmarking Surveillence of Duloxetine Safety in Pregnancy
02/28/2014 - 06/30/2015 (PI)
American Academy of Allergy, Asthma, and Eli Lilly and Co


Phthalates in Drugs and Male Genital Malformations
09/30/2009 - 07/31/2014 (PI)
Harvard School of Public Health NIH NICHD
5R01HD059861-03

Showing 10 of 24 results. Show All Results



Yr Title Project-Sub Proj Pubs
2016 Massachusetts Center for Birth Defects Research and Prevention 5U01DD001037-04
2015 Massachusetts Stillbirth Risk Factor Pilot Project 3U01DD001037-03S1
2015 Massachusetts Center for Birth Defects Research and Prevention 5U01DD001037-03
2014 Massachusetts Center for Birth Defects Research and Prevention 5U01DD001037-02
2013 Massachusetts Center for Birth Defects Research and Prevention 1U01DD001037-01
2013 Specific birth defects and asthma medications in pregnancy: Demonstration project 5R18HS018463-05 2
2013 Massachusetts Center for Birth Defects Research and Prevention 5U01DD000493-05 6
2012 Specific birth defects and asthma medications in pregnancy: Demonstration project 5R18HS018463-04 2
2012 Phthalates in Drugs and Male Genital Malformation 5R01HD059861-04 4
2012 Massachusetts Center for Birth Defects Research and Prevention 5U01DD000493-04 6
Showing 10 of 66 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Kerr S, Van Bennekom CM, Liang JL, Mitchell AA. Tdap Vaccination Coverage During Pregnancy - Selected Sites, United States, 2006-2015. MMWR Morb Mortal Wkly Rep. 2017 Oct 20; 66(41):1105-1108. PMID: 29049273.
  2. Chambers CD, Xu R, Mitchell AA. Commentary on: "Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12". Vaccine. 2017 Sep 25; 35(40):5323-5324. PMID: 28917296.
  3. Kerr S, Van Bennekom CM, Mitchell AA. Influenza Vaccination Coverage During Pregnancy - Selected Sites, United States, 2005-06 Through 2013-14 Influenza Vaccine Seasons. MMWR Morb Mortal Wkly Rep. 2016 Dec 09; 65(48):1370-1373. PMID: 27932781; DOI: 10.15585/mmwr.mm6548a3;.
  4. Louik C, Kerr S, Van Bennekom CM, Chambers C, Jones KL, Schatz M, Mitchell AA. Safety of the 2011-12, 2012-13, and 2013-14 seasonal influenza vaccines in pregnancy: Preterm delivery and specific malformations, a study from the case-control arm of VAMPSS. Vaccine. 2016 Aug 17; 34(37):4450-9. PMID: 27452865; DOI: 10.1016/j.vaccine.2016.06.078;.
  5. Chambers CD, Johnson DL, Xu R, Luo YJ, Louik C, Mitchell AA, Schatz M, Jones KL. Safety of the 2010-11, 2011-12, 2012-13, and 2013-14 seasonal influenza vaccines in pregnancy: Birth defects, spontaneous abortion, preterm delivery, and small for gestational age infants, a study from the cohort arm of VAMPSS. Vaccine. 2016 Aug 17; 34(37):4443-9. PMID: 27449682; DOI: 10.1016/j.vaccine.2016.06.054;.
  6. Benedum CM, Yazdy MM, Parker SE, Mitchell AA, Werler MM. Association of Clomiphene and Assisted Reproductive Technologies With the Risk of Neural Tube Defects. Am J Epidemiol. 2016 Jun 01; 183(11):977-87.View Related Profiles. PMID: 27188944; PMCID: PMC4887580; DOI: 10.1093/aje/kwv322;.
  7. Simeone RM, Feldkamp ML, Reefhuis J, Mitchell AA, Gilboa SM, Honein MA, Iskander J. CDC Grand Rounds: Understanding the Causes of Major Birth Defects - Steps to Prevention. MMWR Morb Mortal Wkly Rep. 2015 Oct 9; 64(39):1104-7. PMID: 26447345; DOI: 10.15585/mmwr.mm6439a3;.
  8. Benedum CM, Yazdy MM, Mitchell AA, Werler MM. Impact of Periconceptional Use of Nitrosatable Drugs on the Risk of Neural Tube Defects. Am J Epidemiol. 2015 Oct 15; 182(8):675-84.View Related Profiles. PMID: 26424074; DOI: 10.1093/aje/kwv126;.
  9. Louik C, Werler M, Anderka M, Mitchell AA. Application of data screening to drug exposure in large risk factor studies of birth defects. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):713-7.View Related Profiles. PMID: 26259777; DOI: 10.1002/bdra.23407;.
  10. Mitchell AA, Louik C, Chambers C, Jones KL, Schatz M. Immunization surveillance systems for pregnant women. Pharmacoepidemiol Drug Saf. 2015 Jun; 24(6):669.View Related Profiles. PMID: 26053022; DOI: 10.1002/pds.3784;.
Showing 10 of 127 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 127 publications over 16 distinct years, with a maximum of 13 publications in 2013

YearPublications
20027
200311
20045
20059
20069
20077
20089
20098
20107
201112
20129
201313
20149
20156
20164
20172
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72 E. Concord St Instructional (L)
Boston MA 02118
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