Ting Zhao | Profiles RNS

Ting Zhao, MD

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Surgery

General Surgery

MD, Peking University

Websites

	LinkedIn
	Scadden Lab Profile
	Harvard Catalyst Profile
	ResearchGate

Ting earned his PhD in Cell Biology from Peking University, China in 2016 under the supervision of Professor Hongkui Deng. In his PhD study, he and colleagues originally developed and optimized a robust chemically-induced reprogramming system, which is a novel approach to convert mature cells into a pluripotent state by the induction of small molecules (Zhao et al., Cell, 2015, co-first author). Then, he and colleagues investigated the molecular roadmap of chemical reprogramming by single-cell RNA-sequencing and uncovered new mechanistic insights into the nature of induced pluripotency (Zhao et al., Cell Stem Cell, 2018).

Roger Williams Medical Center

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Yano N, Zhao YT, Zhao TC. The Physiological Role of Irisin in the Regulation of Muscle Glucose Homeostasis. Endocrines. 2021 Sep; 2(3):266-283. PMID: 35392577; PMCID: PMC8986094; DOI: 10.3390/endocrines2030025;

Du J, Zhao YT, Wang H, Zhang LX, Qin G, Zhuang S, Kadin M, Chin YE, Liu PY, Zhao TC. The Essential Role of PRAK in Preserving Cardiac Function and Insulin Resistance in High-Fat Diet-Induced Diabetes. Int J Mol Sci. 2021 Jul 27; 22(15).View Related Profiles.

Kadin, Marshall
Zhao, Ting

PMID: 34360761; PMCID: PMC8347374; DOI: 10.3390/ijms22157995;

Wang Z, Zhao YT, Zhao TC. Histone deacetylases in modulating cardiac disease and their clinical translational and therapeutic implications. Exp Biol Med (Maywood). 2021 01; 246(2):213-225. PMID: 32727215; PMCID: PMC7871120; DOI: 10.1177/1535370220944128;

Wang J, Zhao YT, Zhang L, Dubielecka PM, Zhuang S, Qin G, Chin YE, Zhang S, Zhao TC. Irisin Improves Myocardial Performance and Attenuates Insulin Resistance in Spontaneous Mutation (Leprdb ) Mice. Front Pharmacol. 2020; 11:769. PMID: 32581784; PMCID: PMC7283381; DOI: 10.3389/fphar.2020.00769;

Zhao TC, Wang Z, Zhao TY. The important role of histone deacetylases in modulating vascular physiology and arteriosclerosis. Atherosclerosis. 2020 06; 303:36-42. PMID: 32535412; PMCID: PMC7385907; DOI: 10.1016/j.atherosclerosis.2020.04.020;

Zhang Y, Zou J, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis. FASEB J. 2020 06; 34(6):7295-7310. PMID: 32281211; PMCID: PMC7445474; DOI: 10.1096/fj.201903254R;

Yano N, Zhang L, Wei D, Dubielecka PM, Wei L, Zhuang S, Zhu P, Qin G, Liu PY, Chin YE, Zhao TC. Irisin counteracts high glucose and fatty acid-induced cytotoxicity by preserving the AMPK-insulin receptor signaling axis in C2C12 myoblasts. Am J Physiol Endocrinol Metab. 2020 05 01; 318(5):E791-E805. PMID: 32182124; PMCID: PMC7272726; DOI: 10.1152/ajpendo.00219.2019;

Han S, Xu S, Zhou J, Qiao A, Boriboun C, Ma W, Li H, Biyashev D, Yang L, Zhang E, Liu Q, Jiang S, Zhao TC, Krishnamurthy P, Zhang C, Richard S, Qiu H, Zhang J, Qin G. Sam68 impedes the recovery of arterial injury by augmenting inflammatory response. J Mol Cell Cardiol. 2019 12; 137:82-92. PMID: 31639388; PMCID: PMC6889069; DOI: 10.1016/j.yjmcc.2019.10.003;

Liu L, Zou J, Guan Y, Zhang Y, Zhang W, Zhou X, Xiong C, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Blocking the histone lysine 79 methyltransferase DOT1L alleviates renal fibrosis through inhibition of renal fibroblast activation and epithelial-mesenchymal transition. FASEB J. 2019 11; 33(11):11941-11958. PMID: 31373855; PMCID: PMC8793787; DOI: 10.1096/fj.201801861R;

Zhao YT, Du J, Yano N, Wang H, Wang J, Dubielecka PM, Zhang LX, Qin G, Zhuang S, Liu PY, Chin YE, Zhao TC. p38-Regulated/activated protein kinase plays a pivotal role in protecting heart against ischemia-reperfusion injury and preserving cardiac performance. Am J Physiol Cell Physiol. 2019 09 01; 317(3):C525-C533. PMID: 31291142; PMCID: PMC6766622; DOI: 10.1152/ajpcell.00122.2019;

Showing 10 of 72 results. Show More

Xiong C, Guan Y, Zhou X, Liu L, Zhuang MA, Zhang W, Zhang Y, Masucci MV, Bayliss G, Zhao TC, Zhuang S. Selective inhibition of class IIa histone deacetylases alleviates renal fibrosis. FASEB J. 2019 07; 33(7):8249-8262. PMID: 30951378; PMCID: PMC6593874; DOI: 10.1096/fj.201801067RR;

James NE, Oliver MT, Ribeiro JR, Cantillo E, Rowswell-Turner RB, Kim KK, Chichester CO, DiSilvestro PA, Moore RG, Singh RK, Yano N, Zhao TC. Human Epididymis Secretory Protein 4 (HE4) Compromises Cytotoxic Mononuclear Cells via Inducing Dual Specificity Phosphatase 6. Front Pharmacol. 2019; 10:216. PMID: 30941033; PMCID: PMC6433991; DOI: 10.3389/fphar.2019.00216;

Zhang YS, Xin DE, Wang Z, Song X, Sun Y, Zou QC, Yue J, Zhang C, Zhang JM, Liu Z, Zhang X, Zhao TC, Su B, Chin YE. STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation. EMBO J. 2019 03 15; 38(6). PMID: 30770344; PMCID: PMC6418461; DOI: 10.15252/embj.201899595;

Zhou X, Zang X, Guan Y, Tolbert T, Zhao TC, Bayliss G, Zhuang S. Targeting enhancer of zeste homolog 2 protects against acute kidney injury. Cell Death Dis. 2018 10 19; 9(11):1067. PMID: 30341286; PMCID: PMC6195522; DOI: 10.1038/s41419-018-1012-0;

Zhang LX, Du J, Zhao YT, Wang J, Zhang S, Dubielecka PM, Wei L, Zhuang S, Qin G, Chin YE, Zhao TC. Transgenic overexpression of active HDAC4 in the heart attenuates cardiac function and exacerbates remodeling in infarcted myocardium. J Appl Physiol (1985). 2018 12 01; 125(6):1968-1978.View Related Profiles.

Dubielecka-Szczerba, Patrycja
Zhao, Ting

PMID: 30284520; PMCID: PMC6737459; DOI: 10.1152/japplphysiol.00006.2018;

Chorzalska A, Morgan J, Ahsan N, Treaba DO, Olszewski AJ, Petersen M, Kingston N, Cheng Y, Lombardo K, Schorl C, Yu X, Zini R, Pacilli A, Tepper A, Coburn J, Hryniewicz-Jankowska A, Zhao TC, Oancea E, Reagan JL, Liang O, Kotula L, Quesenberry PJ, Gruppuso PA, Manfredini R, Vannucchi AM, Dubielecka PM. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018 11 08; 132(19):2053-2066. PMID: 30213875; PMCID: PMC6236464; DOI: 10.1182/blood-2018-05-848408;

James NE, Cantillo E, Oliver MT, Rowswell-Turner RB, Ribeiro JR, Kim KK, Chichester CO, DiSilvestro PA, Moore RG, Singh RK, Yano N, Zhao TC. HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells. Clin Exp Immunol. 2018 09; 193(3):327-340. PMID: 29745428; PMCID: PMC6149960; DOI: 10.1111/cei.13153;

Zhao YT, Wang J, Yano N, Zhang LX, Wang H, Zhang S, Qin G, Dubielecka PM, Zhuang S, Liu PY, Chin YE, Zhao TC. Irisin promotes cardiac progenitor cell-induced myocardial repair and functional improvement in infarcted heart. J Cell Physiol. 2019 02; 234(2):1671-1681. PMID: 30171682; PMCID: PMC6510276; DOI: 10.1002/jcp.27037;

Zhang L, Wang H, Zhao Y, Wang J, Dubielecka PM, Zhuang S, Qin G, Chin YE, Kao RL, Zhao TC. Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury. Mol Med. 2018 07 17; 24(1):37. PMID: 30134825; PMCID: PMC6050730; DOI: 10.1186/s10020-018-0037-2;

Zhou X, Xiong C, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Targeting histone methyltransferase enhancer of zeste homolog-2 inhibits renal epithelial-mesenchymal transition and attenuates renal fibrosis. FASEB J. 2018 May 18; 32(11):fj201800237R. PMID: 29775417; PMCID: PMC6181636; DOI: 10.1096/fj.201800237R;

Chorzalska A, Ahsan N, Rao RSP, Roder K, Yu X, Morgan J, Tepper A, Hines S, Zhang P, Treaba DO, Zhao TC, Olszewski AJ, Reagan JL, Liang O, Gruppuso PA, Dubielecka PM. Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-?B pathways in a model of chronic myeloid leukemia. Mol Oncol. 2018 05; 12(5):630-647. PMID: 29485707; PMCID: PMC5928369; DOI: 10.1002/1878-0261.12186;

Huang C, Zhang Z, Chen L, Lee HW, Ayrapetov MK, Zhao TC, Hao Y, Gao J, Yang C, Mehta GU, Zhuang Z, Zhang X, Hu G, Chin YE. Acetylation within the N- and C-Terminal Domains of Src Regulates Distinct Roles of STAT3-Mediated Tumorigenesis. Cancer Res. 2018 06 01; 78(11):2825-2838. PMID: 29531159

Xu S, Tao J, Yang L, Zhang E, Boriboun C, Zhou J, Sun T, Cheng M, Huang K, Shi J, Dong N, Liu Q, Zhao TC, Qiu H, Harris RA, Chandel NS, Losordo DW, Qin G. E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells. Circ Res. 2018 03 02; 122(5):701-711. PMID: 29358228; PMCID: PMC6021021; DOI: 10.1161/CIRCRESAHA.117.311814;

Xiong C, Zang X, Zhou X, Liu L, Masucci MV, Tang J, Li X, Liu N, Bayliss G, Zhao TC, Zhuang S. Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion. Oncotarget. 2017 May 09; 8(19):31238-31253. PMID: 28415724; PMCID: PMC5458204; DOI: 10.18632/oncotarget.16114;

Wang H, Zhao YT, Zhang S, Dubielecka PM, Du J, Yano N, Chin YE, Zhuang S, Qin G, Zhao TC. Irisin plays a pivotal role to protect the heart against ischemia and reperfusion injury. J Cell Physiol. 2017 Dec; 232(12):3775-3785. PMID: 28181692; PMCID: PMC5550372; DOI: 10.1002/jcp.25857;

Zhang L, Du J, Yano N, Wang H, Zhao YT, Dubielecka PM, Zhuang S, Chin YE, Qin G, Zhao TC. Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice. J Cell Biochem. 2017 08; 118(8):2395-2408. PMID: 28109123; PMCID: PMC5462877; DOI: 10.1002/jcb.25902;

Chorzalska A, Kim JF, Roder K, Tepper A, Ahsan N, Rao RSP, Olszewski AJ, Yu X, Terentyev D, Morgan J, Treaba DO, Zhao TC, Liang O, Gruppuso PA, Dubielecka PM. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017 05 01; 26(9):656-677. PMID: 28103766; PMCID: PMC5421616; DOI: 10.1089/scd.2016.0262;

Wang XJ, Qiao Y, Xiao MM, Wang L, Chen J, Lv W, Xu L, Li Y, Wang Y, Tan MD, Huang C, Li J, Zhao TC, Hou Z, Jing N, Chin YE. Opposing Roles of Acetylation and Phosphorylation in LIFR-Dependent Self-Renewal Growth Signaling in Mouse Embryonic Stem Cells. Cell Rep. 2017 01 24; 18(4):933-946. PMID: 28122243

Ma L, Huang C, Wang XJ, Xin DE, Wang LS, Zou QC, Zhang YS, Tan MD, Wang YM, Zhao TC, Chatterjee D, Altura RA, Wang C, Xu YS, Yang JH, Fan YS, Han BH, Si J, Zhang X, Cheng J, Chang Z, Chin YE. Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation. Mol Cell. 2017 Jan 19; 65(2):296-309. PMID: 28065600

Zhao YT, Wang H, Zhang S, Du J, Zhuang S, Zhao TC. Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4. PLoS One. 2016; 11(11):e0166182. PMID: 27875543; PMCID: PMC5119735; DOI: 10.1371/journal.pone.0166182;

Xiong C, Masucci MV, Zhou X, Liu N, Zang X, Tolbert E, Zhao TC, Zhuang S. Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis. Oncotarget. 2016 10 25; 7(43):69291-69308. PMID: 27732564; PMCID: PMC5342478; DOI: 10.18632/oncotarget.12498;

Du J, Zhang L, Wang Z, Yano N, Zhao YT, Wei L, Dubielecka-Szczerba P, Liu PY, Zhuang S, Qin G, Zhao TC. Exendin-4 induces myocardial protection through MKK3 and Akt-1 in infarcted hearts. Am J Physiol Cell Physiol. 2016 Feb 15; 310(4):C270-83.View Related Profiles.

Dubielecka-Szczerba, Patrycja
Zhao, Ting

PMID: 26739490; PMCID: PMC4864970; DOI: 10.1152/ajpcell.00194.2015;

Zhao YT, Du J, Chen Y, Tang Y, Qin G, Lv G, Zhuang S, Zhao TC. Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium. Stem Cell Res Ther. 2015 Dec 24; 6:259. PMID: 26704423; PMCID: PMC4690244; DOI: 10.1186/s13287-015-0252-5;

Zhou X, Zang X, Ponnusamy M, Masucci MV, Tolbert E, Gong R, Zhao TC, Liu N, Bayliss G, Dworkin LD, Zhuang S. Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression. J Am Soc Nephrol. 2016 07; 27(7):2092-108. PMID: 26701983; PMCID: PMC4926973; DOI: 10.1681/ASN.2015040457;

Chen Y, Du J, Zhao YT, Zhang L, Lv G, Zhuang S, Qin G, Zhao TC. Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. Cardiovasc Diabetol. 2015 Aug 07; 14:99. PMID: 26245924; PMCID: PMC4527099; DOI: 10.1186/s12933-015-0262-8;

Ponnusamy M, Zhuang MA, Zhou X, Tolbert E, Bayliss G, Zhao TC, Zhuang S. Activation of Sirtuin-1 Promotes Renal Fibroblast Activation and Aggravates Renal Fibrogenesis. J Pharmacol Exp Ther. 2015 Aug; 354(2):142-51. PMID: 26022003; PMCID: PMC4518074; DOI: 10.1124/jpet.115.224386;

Zhou J, Cheng M, Boriboun C, Ardehali MM, Jiang C, Liu Q, Han S, Goukassian DA, Tang YL, Zhao TC, Zhao M, Cai L, Richard S, Kishore R, Qin G. Inhibition of Sam68 triggers adipose tissue browning. J Endocrinol. 2015 Jun; 225(3):181-9.View Related Profiles.

Goukassian, David
Zhao, Ting

PMID: 25934704; PMCID: PMC4482239; DOI: 10.1530/JOE-14-0727;

Cheng M, Huang K, Zhou J, Yan D, Tang YL, Zhao TC, Miller RJ, Kishore R, Losordo DW, Qin G. A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progenitor cell recruitment to the ischemic heart. J Mol Cell Cardiol. 2015 Apr; 81:49-53. PMID: 25655934; PMCID: PMC4380859; DOI: 10.1016/j.yjmcc.2015.01.024;

Yan Y, Bai J, Zhou X, Tang J, Jiang C, Tolbert E, Bayliss G, Gong R, Zhao TC, Zhuang S. P2X7 receptor inhibition protects against ischemic acute kidney injury in mice. Am J Physiol Cell Physiol. 2015 Mar 15; 308(6):C463-72. PMID: 25588875; PMCID: PMC4360025; DOI: 10.1152/ajpcell.00245.2014;

Chen HP, Zhao YT, Zhao TC. Histone deacetylases and mechanisms of regulation of gene expression. Crit Rev Oncog. 2015; 20(1-2):35-47. PMID: 25746103; PMCID: PMC4809735

Wu M, Zhou J, Cheng M, Boriboun C, Biyashev D, Wang H, Mackie A, Thorne T, Chou J, Wu Y, Chen Z, Liu Q, Yan H, Yang Y, Jie C, Tang YL, Zhao TC, Taylor RN, Kishore R, Losordo DW, Qin G. E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression. Cardiovasc Res. 2014 Dec 01; 104(3):412-22. PMID: 25341896; PMCID: PMC4296109; DOI: 10.1093/cvr/cvu222;

DeNicola M, Du J, Wang Z, Yano N, Zhang L, Wang Y, Qin G, Zhuang S, Zhao TC. Stimulation of glucagon-like peptide-1 receptor through exendin-4 preserves myocardial performance and prevents cardiac remodeling in infarcted myocardium. Am J Physiol Endocrinol Metab. 2014 Oct 15; 307(8):E630-43. PMID: 25117407; PMCID: PMC4200306; DOI: 10.1152/ajpendo.00109.2014;

Zhang LX, DeNicola M, Qin X, Du J, Ma J, Tina Zhao Y, Zhuang S, Liu PY, Wei L, Qin G, Tang Y, Zhao TC. Specific inhibition of HDAC4 in cardiac progenitor cells enhances myocardial repairs. Am J Physiol Cell Physiol. 2014 Aug 15; 307(4):C358-72. PMID: 24944198; PMCID: PMC4137141; DOI: 10.1152/ajpcell.00187.2013;

Ponnusamy M, Zhou X, Yan Y, Tang J, Tolbert E, Zhao TC, Gong R, Zhuang S. Blocking sirtuin 1 and 2 inhibits renal interstitial fibroblast activation and attenuates renal interstitial fibrosis in obstructive nephropathy. J Pharmacol Exp Ther. 2014 Aug; 350(2):243-56. PMID: 24833701; PMCID: PMC4109489; DOI: 10.1124/jpet.113.212076;

Tang J, Yan Y, Zhao TC, Gong R, Bayliss G, Yan H, Zhuang S. Class I HDAC activity is required for renal protection and regeneration after acute kidney injury. Am J Physiol Renal Physiol. 2014 Aug 01; 307(3):F303-16. PMID: 24808536; PMCID: PMC4121572; DOI: 10.1152/ajprenal.00102.2014;

Chorzalska A, Salloum I, Shafqat H, Khan S, Marjon P, Treaba D, Schorl C, Morgan J, Bryke CR, Falanga V, Zhao TC, Reagan J, Winer E, Olszewski AJ, Al-Homsi AS, Kouttab N, Dubielecka PM. Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia. Leukemia. 2014 Nov; 28(11):2165-77.View Related Profiles.

Dubielecka-Szczerba, Patrycja
Zhao, Ting
Falanga, Vincent

PMID: 24699303; PMCID: PMC4185277; DOI: 10.1038/leu.2014.120;

Wang Z, Qin G, Zhao TC. HDAC4: mechanism of regulation and biological functions. Epigenomics. 2014 Feb; 6(1):139-50. PMID: 24579951; PMCID: PMC4380265; DOI: 10.2217/epi.13.73;

Huang W, Dai B, Wen Z, Millard RW, Yu XY, Luther K, Xu M, Zhao TC, Yang HT, Qi Z, Lasance K, Ashraf M, Wang Y. Molecular strategy to reduce in vivo collagen barrier promotes entry of NCX1 positive inducible pluripotent stem cells (iPSC(NCX¹?)) into ischemic (or injured) myocardium. PLoS One. 2013; 8(8):e70023. PMID: 23990893; PMCID: PMC3749126; DOI: 10.1371/journal.pone.0070023;

Zhao TC. Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection. Cardiovasc Diabetol. 2013 Jun 18; 12:90. PMID: 23777457; PMCID: PMC3700838; DOI: 10.1186/1475-2840-12-90;

Zhao TC, Du J, Zhuang S, Zhuang S, Liu P, Zhang LX. HDAC inhibition elicits myocardial protective effect through modulation of MKK3/Akt-1. PLoS One. 2013; 8(6):e65474. PMID: 23762381; PMCID: PMC3677871; DOI: 10.1371/journal.pone.0065474;

Tang J, Yan Y, Zhao TC, Bayliss G, Yan H, Zhuang S. Class I histone deacetylase activity is required for proliferation of renal epithelial cells. Am J Physiol Renal Physiol. 2013 Aug 01; 305(3):F244-54. PMID: 23698124; PMCID: PMC3742866; DOI: 10.1152/ajprenal.00126.2013;

Zhou J, Cheng M, Liao YH, Hu Y, Wu M, Wang Q, Qin B, Wang H, Zhu Y, Gao XM, Goukassian D, Zhao TC, Tang YL, Kishore R, Qin G. Rosuvastatin enhances angiogenesis via eNOS-dependent mobilization of endothelial progenitor cells. PLoS One. 2013; 8(5):e63126.View Related Profiles.

Goukassian, David
Zhao, Ting

PMID: 23704894; PMCID: PMC3660394; DOI: 10.1371/journal.pone.0063126;

Zhou J, Cheng M, Wu M, Boriboun C, Jujo K, Xu S, Zhao TC, Tang YL, Kishore R, Qin G. Contrasting roles of E2F2 and E2F3 in endothelial cell growth and ischemic angiogenesis. J Mol Cell Cardiol. 2013 Jul; 60:68-71. PMID: 23603666; PMCID: PMC3684263; DOI: 10.1016/j.yjmcc.2013.04.009;

Liu N, He S, Ma L, Ponnusamy M, Tang J, Tolbert E, Bayliss G, Zhao TC, Yan H, Zhuang S. Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling. PLoS One. 2013; 8(1):e54001. PMID: 23342059; PMCID: PMC3546966; DOI: 10.1371/journal.pone.0054001;

Zhang L, Chen B, Zhao Y, Dubielecka PM, Wei L, Qin GJ, Chin YE, Wang Y, Zhao TC. Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts. J Biol Chem. 2012 Nov 16; 287(47):39338-48.View Related Profiles.

Dubielecka-Szczerba, Patrycja
Zhao, Ting

PMID: 23024362; PMCID: PMC3501087; DOI: 10.1074/jbc.M112.379115;

Zhao TC, Zhang L, Liu JT, Guo TL. Disruption of Nox2 and TNFRp55/p75 eliminates cardioprotection induced by anisomycin. Am J Physiol Heart Circ Physiol. 2012 Nov 15; 303(10):H1263-72. PMID: 22982779; PMCID: PMC3517639; DOI: 10.1152/ajpheart.00306.2012;

Ponnusamy M, Liu N, Sellamuthu R, Zhao TC, Mao H, Zhuang S. Autophagy protects against necrotic renal epithelial cell-induced death of renal interstitial fibroblasts. Am J Physiol Renal Physiol. 2012 Jul 01; 303(1):F83-91. PMID: 22496408; PMCID: PMC3431148; DOI: 10.1152/ajprenal.00027.2012;

Zhang L, Qin X, Zhao Y, Fast L, Zhuang S, Liu P, Cheng G, Zhao TC. Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis. J Pharmacol Exp Ther. 2012 Apr; 341(1):285-93. PMID: 22271820; PMCID: PMC3310703; DOI: 10.1124/jpet.111.189910;

Chen HP, Denicola M, Qin X, Zhao Y, Zhang L, Long XL, Zhuang S, Liu PY, Zhao TC. HDAC inhibition promotes cardiogenesis and the survival of embryonic stem cells through proteasome-dependent pathway. J Cell Biochem. 2011 Nov; 112(11):3246-55. PMID: 21751234; PMCID: PMC3357124; DOI: 10.1002/jcb.23251;

Pang M, Ma L, Liu N, Ponnusamy M, Zhao TC, Yan H, Zhuang S. Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins. J Cell Biochem. 2011 Aug; 112(8):2138-48. PMID: 21465537; PMCID: PMC4626014; DOI: 10.1002/jcb.23135;

Tu XL, Xu HS, Wang M, Zhang YH, Litvinov YA, Sun Y, Schatz H, Zhou XH, Yuan YJ, Xia JW, Audi G, Blaum K, Du CM, Geng P, Hu ZG, Huang WX, Jin SL, Liu LX, Liu Y, Ma X, Mao RS, Mei B, Shuai P, Sun ZY, Suzuki H, Tang SW, Wang JS, Wang ST, Xiao GQ, Xu X, Yamaguchi T, Yamaguchi Y, Yan XL, Yang JC, Ye RP, Zang YD, Zhao HW, Zhao TC, Zhang XY, Zhan WL. Direct mass measurements of short-lived A=2Z-1 nuclides (63)Ge, (65)As, (67)Se, and (71)Kr and their impact on nucleosynthesis in the rp process. Phys Rev Lett. 2011 Mar 18; 106(11):112501. PMID: 21469858

Zhao TC, Zhang LX, Cheng G, Liu JT. gp-91 mediates histone deacetylase inhibition-induced cardioprotection. Biochim Biophys Acta. 2010 Jul; 1803(7):872-80. PMID: 20433879; PMCID: PMC2880401; DOI: 10.1016/j.bbamcr.2010.04.007;

Tseng A, Stabila J, McGonnigal B, Yano N, Yang MJ, Tseng YT, Davol PA, Lum LG, Padbury JF, Zhao TC. Effect of disruption of Akt-1 of lin(-)c-kit(+) stem cells on myocardial performance in infarcted heart. Cardiovasc Res. 2010 Sep 01; 87(4):704-12. PMID: 20410290; PMCID: PMC2920805; DOI: 10.1093/cvr/cvq110;

Zhang LX, Zhao Y, Cheng G, Guo TL, Chin YE, Liu PY, Zhao TC. Targeted deletion of NF-kappaB p50 diminishes the cardioprotection of histone deacetylase inhibition. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H2154-63. PMID: 20382965; PMCID: PMC2886620; DOI: 10.1152/ajpheart.01015.2009;

Yano N, Tseng A, Zhao TC, Robbins J, Padbury JF, Tseng YT. Temporally controlled overexpression of cardiac-specific PI3Kalpha induces enhanced myocardial contractility--a new transgenic model. Am J Physiol Heart Circ Physiol. 2008 Oct; 295(4):H1690-4. PMID: 18723766; PMCID: PMC2593510; DOI: 10.1152/ajpheart.00531.2008;

Yano N, Suzuki D, Endoh M, Tseng A, Stabila JP, McGonnigal BG, Zhao TC, Padbury JF, Tseng YT. Beta-adrenergic receptor mediated protection against doxorubicin-induced apoptosis in cardiomyocytes: the impact of high ambient glucose. Endocrinology. 2008 Dec; 149(12):6449-61. PMID: 18719028; PMCID: PMC2613054; DOI: 10.1210/en.2008-0292;

Zhao TC, Tseng A, Yano N, Tseng Y, Davol PA, Lee RJ, Lum LG, Padbury JF. Targeting human CD34+ hematopoietic stem cells with anti-CD45 x anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction. J Appl Physiol (1985). 2008 Jun; 104(6):1793-800. PMID: 18292296; PMCID: PMC3792713; DOI: 10.1152/japplphysiol.01109.2007;

Zhao TC, Cheng G, Zhang LX, Tseng YT, Padbury JF. Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury. Cardiovasc Res. 2007 Dec 01; 76(3):473-81. PMID: 17884027

Yano N, Suzuki D, Endoh M, Zhao TC, Padbury JF, Tseng YT. A novel phosphoinositide 3-kinase-dependent pathway for angiotensin II/AT-1 receptor-mediated induction of collagen synthesis in MES-13 mesangial cells. J Biol Chem. 2007 Jun 29; 282(26):18819-30. PMID: 17493931

Yano N, Ianus V, Zhao TC, Tseng A, Padbury JF, Tseng YT. A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H385-93. PMID: 17369456

Zhao TC, Taher MM, Valerie KC, Kukreja RC. p38 Triggers late preconditioning elicited by anisomycin in heart: involvement of NF-kappaB and iNOS. Circ Res. 2001 Nov 09; 89(10):915-22. PMID: 11701619

Zhao TC, Hines DS, Kukreja RC. Adenosine-induced late preconditioning in mouse hearts: role of p38 MAP kinase and mitochondrial K(ATP) channels. Am J Physiol Heart Circ Physiol. 2001 Mar; 280(3):H1278-85. PMID: 11179074

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 72 publications over 15 distinct years, with a maximum of 10 publications in 2018

Bar chart showing 72 publications over 15 distinct years, with a maximum of 10 publications in 2018

Year	Publications
2001	2
2007	3
2008	3
2010	3
2011	3
2012	4
2013	7
2014	7
2015	8
2016	3
2017	6
2018	10
2019	6
2020	5
2021	2

2010 Chinese Academy of Science, Institute of Genetics and Developmental Biology: K.C. Wong Visiting Scholarship Award

2007 AHA National Center: Scientist Development Grant Award

2001 (AHA Mid-Atlantic Affiliate): Grant-In-Aid

1997 The Royal Society of UK, UK: The Royal Society Research Fellowship Award

1995 China Academy of Sciences, Henan section, China: The Scientific and Technical Advance Award

1993 China Government in 1994, China: The Young Scientist Award

1992 International Society for Heart Research (ISHR), Beijing, China: The Young Investigator Award

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