Paula Saa | Profiles RNS

Paula Saa, PhD

Sr. Postdoctoral Associate (previously held)

Boston University Chobanian & Avedisian School of Medicine

Biochemistry & Cell Biology

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Stone M, Spencer BR, Warden DE, Fink RV, Saa P, Leddy J, Mulach-Vannoy J, Townsend R, Krysztof D, Hughes AN, Di Germanio C, Kessler DA, Kleinman S, Busch MP, Norris PJ. Patient and Immunological Factors Associated With Delayed Clearance of Mucosal Severe Acute Respiratory Syndrome Coronavirus 2 RNA and Symptom Persistence. J Infect Dis. 2024 Aug 16; 230(2):357-362. PMID: 38470857; PMCID: PMC11326823; DOI: 10.1093/infdis/jiae132;

Grimm K, Saá P, Cheedarla N, Gerty MS, Groves JA, Dodd RY, Roback J, Stramer SL. Serologic Testing of US Blood Donations to Identify Severe Acute Respiratory Syndrome Coronavirus 2 and Other Coronaviruses, December 2019 to July 2020. Open Forum Infect Dis. 2024 Jul; 11(7):ofae351. PMID: 39026530; PMCID: PMC11257073; DOI: 10.1093/ofid/ofae351;

Young PP, Saa P. Redefining Blood Donation-Path to Inclusivity and Safety. JAMA. 2023 Nov 21; 330(19):1841-1842. PMID: 37824150

Jones JM, Manrique IM, Stone MS, Grebe E, Saa P, Germanio CD, Spencer BR, Notari E, Bravo M, Lanteri MC, Green V, Briggs-Hagen M, Coughlin MM, Stramer SL, Opsomer J, Busch MP. Estimates of SARS-CoV-2 Seroprevalence and Incidence of Primary SARS-CoV-2 Infections Among Blood Donors, by COVID-19 Vaccination Status - United States, April 2021-September 2022. MMWR Morb Mortal Wkly Rep. 2023 Jun 02; 72(22):601-605. PMID: 37262007; PMCID: PMC10243484; DOI: 10.15585/mmwr.mm7222a3;

Saá P, Fink RV, Dawar H, Di Germanio C, Montalvo L, Wright DJ, Krysztof DE, Kleinman SH, Nester T, Kessler DA, Townsend RL, Spencer BR, Kamel H, Vannoy J, Busch MP, Stramer SL, Stone M, Norris PJ. Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras. Open Forum Infect Dis. 2023 May; 10(5):ofad253. PMID: 37250174; PMCID: PMC10220507; DOI: 10.1093/ofid/ofad253;

Tonnetti L, Dodd RY, Burke DD, Saá P, Spencer BR, Xu M, Haynes JM, Stramer SL. A Longitudinal Study of Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Response in a Subset of United States Blood Donors. Open Forum Infect Dis. 2023 Feb; 10(2):ofac697. PMID: 36751647; PMCID: PMC9898875; DOI: 10.1093/ofid/ofac697;

Busch MP, Stramer SL, Stone M, Yu EA, Grebe E, Notari E, Saa P, Ferg R, Manrique IM, Weil N, Fink RV, Levy ME, Green V, Cyrus S, Williamson PC, Haynes J, Groves J, Krysztof D, Custer B, Kleinman S, Biggerstaff BJ, Opsomer JD, Jones JM. Population-Weighted Seroprevalence From Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection, Vaccination, and Hybrid Immunity Among US Blood Donations From January to December 2021. Clin Infect Dis. 2022 Oct 03; 75(Suppl 2):S254-S263. PMID: 35684973; PMCID: PMC9214177; DOI: 10.1093/cid/ciac470;

Saá P, Fink RV, Bakkour S, Jin J, Simmons G, Muench MO, Dawar H, Di Germanio C, Hui AJ, Wright DJ, Krysztof DE, Kleinman SH, Cheung A, Nester T, Kessler DA, Townsend RL, Spencer BR, Kamel H, Vannoy JM, Dave H, Busch MP, Stramer SL, Stone M, Jackman RP, Norris PJ. Frequent detection but lack of infectivity of SARS-CoV-2 RNA in presymptomatic, infected blood donor plasma. J Clin Invest. 2022 Sep 01; 132(17). PMID: 35834347; PMCID: PMC9435642; DOI: 10.1172/JCI159876;

Fink RV, Fisher L, Sulaeman H, Dave H, Levy ME, McCann L, Di Germanio C, Notari EP, Green V, Cyrus S, Williamson P, Saa P, Haynes JM, Groves J, Mathew S, Kaidarova Z, Bruhn R, Grebe E, Opsomer J, Jones JM, Miller MJ, Busch MP, Stone M. How do we…form and coordinate a national serosurvey of SARS-CoV-2 within the blood collection industry? Transfusion. 2022 Jul; 62(7):1321-1333. PMID: 35607854; PMCID: PMC9348230; DOI: 10.1111/trf.16943;

Stone M, Di Germanio C, Wright DJ, Sulaeman H, Dave H, Fink RV, Notari EP, Green V, Strauss D, Kessler D, Destree M, Saa P, Williamson PC, Simmons G, Stramer SL, Opsomer J, Jones JM, Kleinman S, Busch MP. Use of US Blood Donors for National Serosurveillance of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies: Basis for an Expanded National Donor Serosurveillance Program. Clin Infect Dis. 2022 Mar 09; 74(5):871-881. PMID: 34111244; PMCID: PMC8406874; DOI: 10.1093/cid/ciab537;

Showing 10 of 38 results. Show More

Dodd RY, Notari EP, Brodsky JP, Foster GA, Xu M, Saá P, Stramer SL. Patterns of Antibody Response to Severe Acute Respiratory Syndrome Coronavirus 2 Among 1.6 Million Blood Donors: Impact of Vaccination, United States, December 2020-June 2021. J Infect Dis. 2022 01 05; 225(1):5-9. PMID: 34626465

Jones JM, Stone M, Sulaeman H, Fink RV, Dave H, Levy ME, Di Germanio C, Green V, Notari E, Saa P, Biggerstaff BJ, Strauss D, Kessler D, Vassallo R, Reik R, Rossmann S, Destree M, Nguyen KA, Sayers M, Lough C, Bougie DW, Ritter M, Latoni G, Weales B, Sime S, Gorlin J, Brown NE, Gould CV, Berney K, Benoit TJ, Miller MJ, Freeman D, Kartik D, Fry AM, Azziz-Baumgartner E, Hall AJ, MacNeil A, Gundlapalli AV, Basavaraju SV, Gerber SI, Patton ME, Custer B, Williamson P, Simmons G, Thornburg NJ, Kleinman S, Stramer SL, Opsomer J, Busch MP. Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021. JAMA. 2021 Oct 12; 326(14):1400-1409. PMID: 34473201; PMCID: PMC8414359; DOI: 10.1001/jama.2021.15161;

Dodd RY, Spencer BR, Xu M, Foster GA, Saá P, Brodsky JP, Stramer SL. Characteristics of US Blood Donors Testing Reactive for Antibodies to SARS-CoV-2 Prior to the Availability of Authorized Vaccines. Transfus Med Rev. 2021 07; 35(3):1-7. PMID: 34373145; PMCID: PMC8321690; DOI: 10.1016/j.tmrv.2021.07.001;

Bakkour S, Saá P, Groves JA, Montalvo L, Di Germanio C, Best SM, Grebe E, Livezey K, Linnen JM, Strauss D, Kessler D, Bonn M, Green V, Williamson P, Kleinman S, Stramer SL, Stone M, Busch MP. Minipool testing for SARS-CoV-2 RNA in United States blood donors. Transfusion. 2021 08; 61(8):2384-2391. PMID: 34046906

Saá P, Townsend RL, Wells P, Janzen MA, Brodsky JP, Stramer SL. Qualification of the Geenius HIV 1/2 supplemental assay for use in the HIV blood donation screening algorithm. Transfusion. 2020 08; 60(8):1804-1810. PMID: 32339301

Saá P. Is sporadic Creutzfeldt-Jakob disease transfusion-transmissible? Transfusion. 2020 04; 60(4):655-658. PMID: 32246483

Saa P, Chiu C, Grimm K, Yu G, Benjamin RJ, Corash L, Stramer SL. Acute Zika virus infection in an asymptomatic blood donor at the onset of the Puerto Rico epidemic. Transfusion. 2019 Oct; 59(10):3164-3170. PMID: 31407817; PMCID: PMC6785374; DOI: 10.1111/trf.15484;

Ramachandran S, Groves JA, Xia GL, Saá P, Notari EP, Drobeniuc J, Poe A, Khudyakov N, Schillie SF, Murphy TV, Kamili S, Teo CG, Dodd RY, Khudyakov YE, Stramer SL. Recent and occult hepatitis B virus infections among blood donors in the United States. Transfusion. 2019 02; 59(2):601-611. PMID: 30499591; PMCID: PMC8190636; DOI: 10.1111/trf.15057;

Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ, Kornek M, Kosanovic MM, Kovács ÁF, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Line A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz ÁM, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, et al. Minimal informView Related Profiles.

Saa, Paula
Ikezu, Tsuneya

PMID: 30637094; PMCID: PMC6322352; DOI: 10.1080/20013078.2018.1535750;

Saá P, Proctor M, Foster G, Krysztof D, Winton C, Linnen JM, Gao K, Brodsky JP, Limberger RJ, Dodd RY, Stramer SL. Investigational Testing for Zika Virus among U.S. Blood Donors. N Engl J Med. 2018 05 10; 378(19):1778-1788. PMID: 29742375

Vogel R, Pal AK, Jambhrunkar S, Patel P, Thakur SS, Reátegui E, Parekh HS, Saá P, Stassinopoulos A, Broom MF. High-Resolution Single Particle Zeta Potential Characterisation of Biological Nanoparticles using Tunable Resistive Pulse Sensing. Sci Rep. 2017 12 12; 7(1):17479. PMID: 29234015; PMCID: PMC5727177; DOI: 10.1038/s41598-017-14981-x;

Elezgarai SR, Fernández-Borges N, Eraña H, Sevillano AM, Charco JM, Harrathi C, Saá P, Gil D, Kong Q, Requena JR, Andréoletti O, Castilla J. Generation of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome. Sci Rep. 2017 08 29; 7(1):9584. PMID: 28851967; PMCID: PMC5575253; DOI: 10.1038/s41598-017-09489-3;

Cervenakova L, Saá P, Yakovleva O, Vasilyeva I, de Castro J, Brown P, Dodd R. Are prions transported by plasma exosomes? Transfus Apher Sci. 2016 Aug; 55(1):70-83. PMID: 27499183; DOI: 10.1016/j.transci.2016.07.013;

Saá P, Harris DA, Cervenakova L. Mechanisms of prion-induced neurodegeneration. Expert Rev Mol Med. 2016 Apr 08; 18:e5.View Related Profiles.

Harris, David
Saa, Paula

PMID: 27055367; DOI: 10.1017/erm.2016.8;

Saá P, Cervenakova L. Protein misfolding cyclic amplification (PMCA): Current status and future directions. Virus Res. 2015 Sep 2; 207:47-61. PMID: 25445341; DOI: 10.1016/j.virusres.2014.11.007;

Saá P, Yakovleva O, de Castro J, Vasilyeva I, De Paoli SH, Simak J, Cervenakova L. First demonstration of transmissible spongiform encephalopathy-associated prion protein (PrPTSE) in extracellular vesicles from plasma of mice infected with mouse-adapted variant Creutzfeldt-Jakob disease by in vitro amplification. J Biol Chem. 2014 Oct 17; 289(42):29247-60. PMID: 25157106; PMCID: PMC4200276; DOI: 10.1074/jbc.M114.589564;

Saá P, Sferrazza GF, Ottenberg G, Oelschlegel AM, Dorsey K, Lasmézas CI. Strain-specific role of RNAs in prion replication. J Virol. 2012 Oct; 86(19):10494-504. PMID: 22811520; PMCID: PMC3457318; DOI: 10.1128/JVI.01286-12;

Turnbaugh JA, Unterberger U, Saá P, Massignan T, Fluharty BR, Bowman FP, Miller MB, Supattapone S, Biasini E, Harris DA. The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc). J Neurosci. 2012 Jun 27; 32(26):8817-30.View Related Profiles.

Harris, David
Biasini, Emiliano
Saa, Paula
Massignan, Tania
Unterberger, Ursula

PMID: 22745483; PMCID: PMC3433751; DOI: 10.1523/JNEUROSCI.1103-12.2012;

Karapetyan YE, Saá P, Mahal SP, Sferrazza GF, Sherman A, Salès N, Weissmann C, Lasmézas CI. Prion strain discrimination based on rapid in vivo amplification and analysis by the cell panel assay. PLoS One. 2009; 4(5):e5730. PMID: 19478942; PMCID: PMC2684634; DOI: 10.1371/journal.pone.0005730;

Castilla J, Morales R, Saá P, Barria M, Gambetti P, Soto C. Cell-free propagation of prion strains. EMBO J. 2008 Oct 8; 27(19):2557-66. PMID: 18800058; PMCID: PMC2567411; DOI: 10.1038/emboj.2008.181;

Castilla J, Gonzalez-Romero D, Saá P, Morales R, De Castro J, Soto C. Crossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions. Cell. 2008 Sep 5; 134(5):757-68. PMID: 18775309; PMCID: PMC2740631; DOI: 10.1016/j.cell.2008.07.030;

Saá P, Castilla J, Soto C. Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification. J Biol Chem. 2006 Nov 17; 281(46):35245-52. PMID: 16982620

Saá P, Castilla J, Soto C. Presymptomatic detection of prions in blood. Science. 2006 Jul 7; 313(5783):92-4. PMID: 16825570

Castilla J, Saá P, Morales R, Abid K, Maundrell K, Soto C. Protein misfolding cyclic amplification for diagnosis and prion propagation studies. Methods Enzymol. 2006; 412:3-21. PMID: 17046648

Castilla J, Saá P, Soto C. Detection of prions in blood. Nat Med. 2005 Sep; 11(9):982-5. PMID: 16127436

Castilla J, Saá P, Hetz C, Soto C. In vitro generation of infectious scrapie prions. Cell. 2005 Apr 22; 121(2):195-206. PMID: 15851027

Soto C, Anderes L, Suardi S, Cardone F, Castilla J, Frossard MJ, Peano S, Saa P, Limido L, Carbonatto M, Ironside J, Torres JM, Pocchiari M, Tagliavini F. Pre-symptomatic detection of prions by cyclic amplification of protein misfolding. FEBS Lett. 2005 Jan 31; 579(3):638-42. PMID: 15670821

Saá P, Castilla J, Soto C. Cyclic amplification of protein misfolding and aggregation. Methods Mol Biol. 2005; 299:53-65. PMID: 15980595

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 38 publications over 15 distinct years, with a maximum of 6 publications in 2022

Bar chart showing 38 publications over 15 distinct years, with a maximum of 6 publications in 2022

Year	Publications
2005	4
2006	3
2008	2
2009	1
2012	2
2014	2
2016	2
2017	2
2018	3
2019	1
2020	2
2021	3
2022	6
2023	3
2024	2

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