Mark H. Mirochnick, MD
Professor
Boston University School of Medicine
Dept of Pediatrics
Neonatology

MD, University of Vermont College of Medicine




Mark Mirochnick, MD is Professor of Pediatrics and a member of the Division of Neonatology at Boston University School of Medicine/Boston Medical Center. His main research activities involve investigating the pharmacology of HIV and TB drugs in newborns, infants, children and pregnant women. He has served as protocol chair, investigator and/or protocol pharmacologist on many international protocol teams in this area. He currently serves as co-chair of the US Perinatal HIV Guidelines Committee and is a member of the US Pediatric HIV Guidelines Committee and the WHO Pediatric Antiretroviral Working Group.

Section Director
Boston University School of Medicine
Pediatrics
Neonatology



A 48 Week, Phase II, Open-Label, Multi-Cohort, Multicenter Study to Evaluate the Safety , Tolerability, Pharmacokinetics, and Antiviral Activity of GW433908/Ritonavir QD when Administered to HIV-1 Infected, Antiretrovitral Naive and Experienced, Pediatric
07/01/2002 - 06/30/2006 (PI)
GlaxoSmithKline, Inc.

Open-Label Multicenter Multiple Dose Phase III Study of the Population Pharmacokinetics of IV Synecid 7.5 mg/kg q8h in &5 Pediatric Patients
11/01/2001 - 10/31/2003 (PI)
Aventis Pharmaceuticals Inc

Investigation of CD11b Expression in Neonates Using New Laser Scanning Cytometer Technology
10/19/1999 - 09/30/2000 (PI)
CompuCyte Corporation


Pharmacokinetics and Safety of Remdesivir for Treatment of C
06/01/2020 - 11/30/2022 (PI)
Johns Hopkins University National Institute o

LDR 01: LOC-IMPAACT Leadership Group: Mirochnick_Yr09
01/01/2014 - 11/30/2022 (PI)
Johns Hopkins University National Institute o

Enhanced maternal and fetal PBPK models to predict drug exposures of novel oral and long-acting antivirals during pregnancy
08/09/2020 - 07/31/2021 (PI)
The Regents of the University of Calif., U.C. San Diego National Institute o

LDR09 - P1026s: Pharmacokinetic Properties of Antiretroviral and Related Drugs During Pregnancy...
07/01/2018 - 06/30/2021 (PI)
Johns Hopkins University Gilead Sciences

IMPAACT 2007 - Phase I Safety and Pharmacokeneticks of Marviorc in HIV 1 Exposed Infants at Risk …
07/01/2016 - 12/31/2020 (PI)
Johns Hopkins University Phivco UK II Ltd.

Plugging Hair ARV Levels as Adherence Biomarkers into HIV Prevention Trials
12/01/2012 - 11/30/2016 (PI)
Univ of California, San Francisco NIH-NIAID

IMPAACT: HIV Treatment SC VC
06/01/2012 - 12/31/2014 (PI)
Johns Hopkins University NIH-NIAID

IMPAACT: Network Executive Committee (NEC)
06/01/2012 - 12/31/2013 (PI)
Johns Hopkins University NIH-NIAID

IMPAACT Group Leadership
07/01/2006 - 06/30/2013 (PI)
Social & Scientific Systems Inc. NIH-NIAID

Pharmacokinetic Study of Praziquantel During Pregnancy
04/01/2009 - 03/31/2013 (PI)
Rhode Island Hospital NIH-NIAID

Showing 10 of 17 results. Show All Results

Title


Yr Title Project-Sub Proj Pubs
2008 Safety Pharmacokinetics &Efficacy of Artemether &Lumefantrine in Pregnant Women 1R34AI076610-01
2007 ANTIRETROVIRAL DRUGS DURING PREGNANCY, SUBSTUDY OF PACTG P1025 2M01RR000533-39-8139 503
2007 PERINATAL CORE PROTOCOL FOR HIV INFECTED WOMEN (PACTG P1025, VERSION 20) 2M01RR000533-39-8144 503
2007 PHARMACOKINETICS OF ANTIRETROVIRAL DRUGS IN PREGNANT HIV INFECTED WOMEN 2M01RR000533-39-8160 503
2006 ANTIRETROVIRAL DRUGS DURING PREGNANCY, HIV INFECTED WOMEN (SUB OF PACTG P1025) 5M01RR000533-38-5584 503
2006 PERINATAL CORE PROTOCOL FOR HIV INFECTED WOMEN (PACTG P1025, VERSION 20) 5M01RR000533-38-5591 503
2006 Antiretroviral Pharmacology/Lactating Mother/Infants 5R21HD051470-02 1
2005 Antiretroviral Pharmacology/Lactating Mother/Infants 1R21HD051470-01 1
2005 ANTIRETROVIRAL DRUGS DURING PREGNANCY IN HIV POSITIVE FEMALES 5M01RR000533-37-5424 503
2005 PERINATAL CORE PROTOCOL IN HIV INFECTED WOMEN (PACTG P1025, VERSION 20) 5M01RR000533-37-444 503
Showing 10 of 22 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Momper JD, Wang J, Stek A, Shapiro DE, Powis KM, Paul ME, Badell ML, Browning R, Chakhtoura N, Denson K, Rungruengthanakit K, George K, Capparelli EV, Mirochnick M, Best BM. Pharmacokinetics of Atazanavir Boosted With Cobicistat in Pregnant and Postpartum Women With HIV. J Acquir Immune Defic Syndr. 2022 03 01; 89(3):303-309. PMID: 34732682; PMCID: PMC8837686; DOI: 10.1097/QAI.0000000000002856;
     
  2. Brooks KM, Pinilla M, Stek AM, Shapiro DE, Barr E, Febo IL, Paul ME, Deville JG, George K, Knowles K, Rungruengthanakit K, Browning R, Chakhtoura N, Capparelli EV, Mirochnick M, Best BM. Pharmacokinetics of tenofovir alafenamide with boosted protease inhibitors in pregnant and postpartum women living with HIV: Results from IMPAACT P1026s. J Acquir Immune Defic Syndr. 2022 Feb 21. PMID: 35195573
     
  3. Béranger A, Bekker A, Solans BP, Cotton MF, Mirochnick M, Violari A, Wang J, Cababasay M, Wiesner L, Browning R, Moye J, Capparelli EV, Savic RM. Influence of NAT2 genotype and maturation on isoniazid exposure in low-birth-weight and preterm infants with or without HIV exposure. Clin Infect Dis. 2022 Feb 04. PMID: 35134861
     
  4. Piscitelli J, Nikanjam M, Best BM, Acosta E, Mirochnick M, Clarke DF, Capparelli EV, Momper JD. Optimizing Dolutegravir Initiation in Neonates Using Population Pharmacokinetic Modeling and Simulation. J Acquir Immune Defic Syndr. 2022 01 01; 89(1):108-114.View Related Profiles. PMID: 34629412; PMCID: PMC8665018; DOI: 10.1097/QAI.0000000000002830;
     
  5. Bekker A, Capparelli EV, Violari A, Cotton MF, Cababasay M, Wang J, Mathiba R, Wiesner L, Wiznia A, Samson P, Browning R, Moye J, Nakwa FL, Decloedt E, Rabie H, Mirochnick M, Cressey TR. Abacavir dosing in neonates from birth to 3 months of life: a population pharmacokinetic modelling and simulation study. Lancet HIV. 2022 01; 9(1):e24-e31. PMID: 34883066; PMCID: PMC8760861; DOI: 10.1016/S2352-3018(21)00266-6;
     
  6. Frenkel LM, Morrison RL, Fuller TL, Gouvêa MI, Benamor Teixeira ML, Coombs RW, Shapiro DE, Mirochnick M, Hennessey R, Whitson K, Chakhtoura N, João EC. Brief Report: Vaginal Viral Shedding With Undetectable Plasma HIV Viral Load in Pregnant Women Receiving 2 Different Antiretroviral Regimens: A Randomized Clinical Trial. J Acquir Immune Defic Syndr. 2021 12 01; 88(4):361-365. PMID: 34369908; PMCID: PMC8547747; DOI: 10.1097/QAI.0000000000002771;
     
  7. Denti P, Wasmann RE, Francis J, McIlleron H, Sugandhi N, Cressey TR, Mirochnick M, Capparelli EV, Penazzato M. One dose does not fit all: revising the WHO paediatric dosing tool to include the non-linear effect of body size and maturation. Lancet Child Adolesc Health. 2022 01; 6(1):9-10. PMID: 34678142
     
  8. Zhao S, Gockenbach M, Grimstein M, Sachs HC, Mirochnick M, Struble K, Belew Y, Wang J, Capparelli EV, Best BM, Johnson T, Momper JD, Maharaj AR. Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development. Front Pediatr. 2021; 9:721059. PMID: 34722417; PMCID: PMC8550258; DOI: 10.3389/fped.2021.721059;
     
  9. Kreitchmann R, Stek A, Best BM, Capparelli E, Wang J, Shapiro D, Chakhtoura N, Mirochnick M, Eke AC. Interactions between etonogestrel-releasing contraceptive implant and 3 antiretroviral regimens. Contraception. 2022 01; 105:67-74. PMID: 34407424; PMCID: PMC8678338; DOI: 10.1016/j.contraception.2021.08.006;
     
  10. Mulligan N, Salama E, Momper JD, Capparelli EV, Stek A, Chakhtoura N, Mirochnick M, Best BM. Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. J Clin Pharm Ther. 2021 Oct; 46(5):1459-1464. PMID: 34254323; PMCID: PMC8448937; DOI: 10.1111/jcpt.13477;
     
Showing 10 of 148 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 148 publications over 34 distinct years, with a maximum of 14 publications in 2020

YearPublications
19863
19881
19901
19911
19933
19943
19951
19962
19971
19983
19997
20004
20013
20023
20033
20041
20054
20063
20072
20086
20093
20103
20119
20125
20134
20147
20155
20162
20174
201810
201911
202014
202112
20224
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Neonatology
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