Krista Huybrechts, PhD
Adjunct Assistant Professor
Boston University School of Public Health
Epidemiology

PhD, Boston University School of Public Health
MS, University of Antwerp
BS, University of Antwerp



Krista F. Huybrechts, M.S., Ph.D. is an Associate Professor of Medicine at Harvard Medical School and an epidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women’s Hospital. She also holds an appointment as adjunct Assistant Professor of Epidemiology at Boston University School of Public Health. Her research centers on the utilization, comparative safety and effectiveness of prescription medications in pregnant women and their offspring, and on studying the outcomes of medications for mental health disorders in vulnerable populations. She also has a special interest in research methodology and innovative research applications in relation to both these fields of study. She currently serves on the Board of Directors of the International Society of Pharmacoepidemiology and Therapeutic Risk Management and is a member of FDA’s Drug Safety and Risk Management Advisory Committee.

Her research centers on the utilization, comparative safety and effectiveness of prescription medications in pregnant women and their offspring (www.harvardpreg.org), and on studying the outcomes of medications for mental health disorders in vulnerable populations. She also has a special interest in research methodology and innovative research applications in relation to both these fields of study.

Dr. Huybrechts graduated magna cum laude with a Master of Science degree in Economics from the University of Antwerp, Belgium where she also worked as a researcher in health economics. Prior to completing a doctoral degree in epidemiology at Boston University School of Public Health, Dr. Huybrechts held several positions in pharmacoeconomics and outcomes research, both in Europe and the US. Her research projects focused primarily on psychiatry and neurology, and covered a broad spectrum of research designs, including clinical trials, naturalistic studies, retrospective data analyses, and decision-analytic simulation models.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Suarez EA, Bateman BT, Hernandez-Diaz S, Straub L, McDougle CJ, Wisner KL, Gray KJ, Pennell PB, Lester B, Zhu Y, Mogun H, Huybrechts KF. Prescription Stimulant Use During Pregnancy and Risk of Neurodevelopmental Disorders in Children. JAMA Psychiatry. 2024 May 01; 81(5):477-488.View Related Profiles. PMID: 38265792; PMCID: PMC10809143; DOI: 10.1001/jamapsychiatry.2023.5073;
     
  2. Chiu YH, Huybrechts KF, Zhu Y, Straub L, Bateman BT, Logan R, Hernández-Díaz S. Internal validation of gestational age estimation algorithms in healthcare databases using pregnancies conceived with fertility procedures. Am J Epidemiol. 2024 Apr 06. PMID: 38583933
     
  3. Hernández-Díaz S, Straub L, Bateman BT, Zhu Y, Mogun H, Wisner KL, Gray KJ, Lester B, McDougle CJ, DiCesare E, Pennell PB, Huybrechts KF. Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure. N Engl J Med. 2024 Mar 21; 390(12):1069-1079. PMID: 38507750; PMCID: PMC11047762; DOI: 10.1056/NEJMoa2309359;
     
  4. Suarez EA, Bateman BT, Straub L, Hernández-Díaz S, Jones HE, Gray KJ, Connery HS, Davis JM, Lester B, Terplan M, Zhu Y, Vine SM, Mogun H, Huybrechts KF. First Trimester Use of Buprenorphine or Methadone and the Risk of Congenital Malformations. JAMA Intern Med. 2024 Mar 01; 184(3):242-251. PMID: 38252426; PMCID: PMC10804281; DOI: 10.1001/jamainternmed.2023.6986;
     
  5. Cesta CE, Rotem R, Bateman BT, Chodick G, Cohen JM, Furu K, Gissler M, Huybrechts KF, Kjerpeseth LJ, Leinonen MK, Pazzagli L, Zoega H, Seely EW, Patorno E, Hernández-Díaz S. Safety of GLP-1 Receptor Agonists and Other Second-Line Antidiabetics in Early Pregnancy. JAMA Intern Med. 2024 Feb 01; 184(2):144-152. PMID: 38079178; PMCID: PMC10714281; DOI: 10.1001/jamainternmed.2023.6663;
     
  6. Brown JP, Yland J JJ, Williams PL, Huybrechts KF, Hernández-Díaz S. Accounting for Twins and Other Multiple Births in Perinatal Studies Conducted Using Healthcare Administration Data. medRxiv. 2024 Jan 24. PMID: 38343813; PMCID: PMC10854318; DOI: 10.1101/2024.01.23.24301685;
     
  7. Savage TJ, Kronman MP, Huybrechts KF. Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis-Reply. JAMA. 2024 Jan 16; 331(3):258-259. PMID: 38227036
     
  8. Shupler M, Huybrechts K, Leung M, Wei Y, Schwartz J, Li L, Koutrakis P, Hernández-Díaz S, Papatheodorou S. Short-Term Increases in NO2 and O3 Concentrations during Pregnancy and Stillbirth Risk in the U.S.: A Time-Stratified Case-Crossover Study. Environ Sci Technol. 2024 Jan 16; 58(2):1097-1108. PMID: 38175714; PMCID: PMC11152641; DOI: 10.1021/acs.est.3c05580;
     
  9. Huybrechts KF, Olfson M. Evaluating the Liability of Antidepressants to Induce Mania in Children and Adolescents With Depression. JAMA Psychiatry. 2024 Jan 01; 81(1):13-14. PMID: 37755866
     
  10. Cohen JM, Alvestad S, Suarez EA, Schaffer A, Selmer RM, Havard A, Bateman BT, Cesta CE, Zoega H, Odsbu I, Huybrechts KF, Kjerpeseth LJ, Straub L, Leinonen MK, Bjørk MH, Nørgaard M, Gissler M, Ulrichsen SP, Hernandez-Diaz S, Tomson T, Furu K. Comparative Risk of Major Congenital Malformations With Antiseizure Medication Combinations vs Valproate Monotherapy in Pregnancy. Neurology. 2024 Jan 23; 102(2):e207996.View Related Profiles. PMID: 38165339; PMCID: PMC10870741; DOI: 10.1212/WNL.0000000000207996;
     
Showing 10 of 211 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 210 publications over 26 distinct years, with a maximum of 26 publications in 2020

YearPublications
19991
20002
20012
20024
20031
20041
20053
20062
20071
20082
20091
20101
20115
20126
20139
201411
201512
20167
201722
201819
201914
202026
202118
202216
202315
20249


2018 American Psychiatric Association, American Journal of Psychiatry: Invited to APA press briefing
2017 Annals of Internal Medicine: Reviewer Recognition
2016 Journal of Pharmacoepidemiology & Drug Safety: Best Reviewer designation
2016 Department of Medicine, Brigham and Women’s Hospital: 2016 DOM Early Career Faculty Mentoring Award
2015 Clinical Research Forum: “Top 10 Clinical Research Achievement Award”
2014 Canadian Medical Association Journal: Reviewer Recognition
2013 Journal of Clinical Psychopharmacology: 2012 Mitchell B. Balter Award
2013 Journal of Clinical Psychopharmacology: Journal of Clinical Psychopharmacology
2013 Journal of Clinical Epidemiology: JCE Reviewer Award
2013 Journal of Pharmacoepidemiology & Drug Safety: Best Reviewer
2011 Honorary Society in Public Health: Induction in Delta Omega (Alpha Beta chapter)
2010 Boston University School of Public Health: School of Public Health Dean’s Award
2010 International Society for Pharmacoepidemiology: Best Student Drug Utilization Abstract
1990 Belgian Association of Health Economists: Dr. Paul Janssen Health Economics Prize
Contact for Mentoring:

715 Albany Street
Boston MA 02118
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