Krista Huybrechts, PhD
Adjunct Assistant Professor
Boston University School of Public Health
Epidemiology

PhD, Boston University School of Public Health
MS, University of Antwerp
BS, University of Antwerp



Krista F. Huybrechts, M.S., Ph.D. is an Associate Professor of Medicine at Harvard Medical School and an epidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women’s Hospital. She also holds an appointment as adjunct Assistant Professor of Epidemiology at Boston University School of Public Health. Her research centers on the utilization, comparative safety and effectiveness of prescription medications in pregnant women and their offspring, and on studying the outcomes of medications for mental health disorders in vulnerable populations. She also has a special interest in research methodology and innovative research applications in relation to both these fields of study. She currently serves on the Board of Directors of the International Society of Pharmacoepidemiology and Therapeutic Risk Management and is a member of FDA’s Drug Safety and Risk Management Advisory Committee.

Her research centers on the utilization, comparative safety and effectiveness of prescription medications in pregnant women and their offspring (www.harvardpreg.org), and on studying the outcomes of medications for mental health disorders in vulnerable populations. She also has a special interest in research methodology and innovative research applications in relation to both these fields of study.

Dr. Huybrechts graduated magna cum laude with a Master of Science degree in Economics from the University of Antwerp, Belgium where she also worked as a researcher in health economics. Prior to completing a doctoral degree in epidemiology at Boston University School of Public Health, Dr. Huybrechts held several positions in pharmacoeconomics and outcomes research, both in Europe and the US. Her research projects focused primarily on psychiatry and neurology, and covered a broad spectrum of research designs, including clinical trials, naturalistic studies, retrospective data analyses, and decision-analytic simulation models.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. McEwen I, Huybrechts KF, Straub L, Hernández-Díaz S. Patterns of paternal medication dispensation around the time of conception. Paediatr Perinat Epidemiol. 2024 Jul 01. PMID: 38949455
     
  2. Chiu YH, Huybrechts KF, Patorno E, Yland JJ, Cesta CE, Bateman BT, Seely EW, Hernán MA, Hernández-Díaz S. Metformin Use in the First Trimester of Pregnancy and Risk for Nonlive Birth and Congenital Malformations: Emulating a Target Trial Using Real-World Data. Ann Intern Med. 2024 Jul; 177(7):862-870. PMID: 38885505
     
  3. Rotem RS, Weisskopf MG, Huybrechts KF, Hernández-Díaz S. Paternal Use of Metformin During the Sperm Development Period Preceding Conception and Risk for Major Congenital Malformations in Newborns. Ann Intern Med. 2024 Jul; 177(7):851-861. PMID: 38885501
     
  4. Leonard SA, Siadat S, Main EK, Huybrechts KF, El-Sayed YY, Hlatky MA, Atkinson J, Sujan A, Bateman BT. Chronic Hypertension During Pregnancy: Prevalence and Treatment in the United States, 2008-2021. Hypertension. 2024 Aug; 81(8):1716-1723. PMID: 38881466
     
  5. Basham CA, Edrees H, Huybrechts KF, Hwang CS, Bateman BT, Bykov K. Tramadol use in U.S. Adults With Commercial Health Insurance, 2005-2021. Am J Prev Med. 2024 Jun 12. PMID: 38876295
     
  6. Brown J, Huybrechts K, Straub L, Heider D, Bateman B, Hernandez-Diaz S. Use of Real-World Data and Machine Learning to Screen for Maternal and Paternal Characteristics Associated with Cardiac Malformations. Res Sq. 2024 Jun 11.View Related Profiles. PMID: 38947037; PMCID: PMC11213223; DOI: 10.21203/rs.3.rs-4490534/v1;
     
  7. Anike O, Zhang Q, Bhasin S, Flanders WD, Getahun D, Haw JS, Huybrechts KF, Lash TL, McCracken CE, Roblin D, Silverberg MJ, Suglia SF, Tangpricha V, Vupputuri S, Goodman M. Association between gender-affirming hormone therapy and measures of glucose metabolism: A longitudinal study. J Clin Endocrinol Metab. 2024 May 30. PMID: 38815002
     
  8. Shupler M, Huybrechts K, Leung M, Wei Y, Schwartz J, Hernandez-Diaz S, Papatheodorou S. The association of short-term increases in ambient PM2.5 and temperature exposures with stillbirth: racial/ethnic disparities among Medicaid recipients. Am J Epidemiol. 2024 May 20.View Related Profiles. PMID: 38770979
     
  9. Mahesri M, Sarpatwari A, Huybrechts KF, Lii J, Lee SB, Toyserkani GA, LaCivita C, Zhou EH, Dal Pan GJ, Kesselheim AS, Bykov K. Trends in Use and Evidence of Adherence to Risk Evaluation and Mitigation Strategy Pregnancy Testing Requirements for Thalidomide, Lenalidomide, and Pomalidomide in the USA, 2000-2020. Drug Saf. 2024 May 16. PMID: 38755509
     
  10. Suarez EA, Bateman BT, Hernandez-Diaz S, Straub L, McDougle CJ, Wisner KL, Gray KJ, Pennell PB, Lester B, Zhu Y, Mogun H, Huybrechts KF. Prescription Stimulant Use During Pregnancy and Risk of Neurodevelopmental Disorders in Children. JAMA Psychiatry. 2024 May 01; 81(5):477-488.View Related Profiles. PMID: 38265792; PMCID: PMC10809143; DOI: 10.1001/jamapsychiatry.2023.5073;
     
Showing 10 of 222 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 221 publications over 26 distinct years, with a maximum of 26 publications in 2020

YearPublications
19991
20002
20012
20024
20031
20041
20053
20062
20071
20082
20091
20101
20115
20126
20139
201411
201512
20167
201722
201819
201914
202026
202118
202216
202315
202420


2018 American Psychiatric Association, American Journal of Psychiatry: Invited to APA press briefing
2017 Annals of Internal Medicine: Reviewer Recognition
2016 Journal of Pharmacoepidemiology & Drug Safety: Best Reviewer designation
2016 Department of Medicine, Brigham and Women’s Hospital: 2016 DOM Early Career Faculty Mentoring Award
2015 Clinical Research Forum: “Top 10 Clinical Research Achievement Award”
2014 Canadian Medical Association Journal: Reviewer Recognition
2013 Journal of Clinical Psychopharmacology: 2012 Mitchell B. Balter Award
2013 Journal of Clinical Psychopharmacology: Journal of Clinical Psychopharmacology
2013 Journal of Clinical Epidemiology: JCE Reviewer Award
2013 Journal of Pharmacoepidemiology & Drug Safety: Best Reviewer
2011 Honorary Society in Public Health: Induction in Delta Omega (Alpha Beta chapter)
2010 Boston University School of Public Health: School of Public Health Dean’s Award
2010 International Society for Pharmacoepidemiology: Best Student Drug Utilization Abstract
1990 Belgian Association of Health Economists: Dr. Paul Janssen Health Economics Prize
Contact for Mentoring:

715 Albany Street
Boston MA 02118
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