Jeroen Eyckmans, PhD
Research Assistant Professor
Boston University College of Engineering
Biomedical Engineering




Dr. Eyckmans’s research program aims to understands the mechanical and biochemical mechanisms that drive tissue repair (scarring) versus tissue regeneration in response to injury. Through an interdisciplinary approach combining microfabrication, nanotechnology and molecular biology, his group develops novel biomimetic models to study wound closure and extracellular matrix remodeling of soft (skin, tendon, ligament) and mineralized (bone, teeth) tissues. Ultimately, the goal is to harness tissue repair and regeneration mechanisms to rationally design targeted tissue engineering strategies for the healing of musculoskeletal tissues after injury.


Targeting extracellular matrix-senescence crosstalk as a novel approach to improve tissue repair in aging
04/01/2024 - 03/31/2028 (Multi-PI)
PI: Jeroen Eyckmans, PhD
Hevolution Foundation


Mechanosensing in lung fibrosis
07/15/2024 - 06/30/2027 (Subcontract PI)
Georgia Institute of Technology NIH NHLBI
1R01HL175067-01

Understanding the Role of Mechanical Boundary Conditions on Tissue Assembly and Repair in 3D Fibrous Microtissues
08/31/2023 - 07/31/2026 (Multi-PI)
PI: Jeroen Eyckmans, PhD
National Science Foundation
CMMI-2311640

EAGER: (ST2) Engineering Biomaterials that Integrate in the Native ECM of Cells.
07/15/2022 - 06/30/2026 (PI)
National Science Foundation
DMR-2036842

Development of a wound-on-chip model to study stromal-epithelial interactions during tissue repair
04/01/2020 - 12/31/2023 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5R21EB028491-03



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Ching T, van Steen ACI, Gray-Scherr D, Teo JL, Vasan A, Jeon J, Shah J, Patel A, Stoddard AE, Bays JL, Eyckmans J, Chen CS. TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration. Lab Chip. 2025 Mar 11; 25(6):1474-1488.View Related Profiles. PMID: 39907088; PMCID: PMC11795533; DOI: 10.1039/d4lc00970c;
     
  2. Pandian NKR, Farell A, Davis E, Sundaram S, van Steen ACI, Chang Teo JL, Eyckmans J, Chen CS. Three-dimensional modeling of flow through microvascular beds and surrounding interstitial spaces. bioRxiv. 2025 Feb 15.View Related Profiles. PMID: 39990367; PMCID: PMC11844386; DOI: 10.1101/2024.02.28.582152;
     
  3. Sundaram S, Lee JH, Bjørge IM, Michas C, Kim S, Lammers A, Mano JF, Eyckmans J, White AE, Chen CS. Sacrificial capillary pumps to engineer multiscalar biological forms. Nature. 2024 Dec; 636(8042):361-367.View Related Profiles. PMID: 39663490
     
  4. Uroz M, Stoddard AE, Sutherland BP, Courbot O, Oria R, Li L, Ravasio CR, Ngo MT, Yang J, Tefft JB, Eyckmans J, Han X, Elosegui-Artola A, Weaver VM, Chen CS. Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option. Nat Cell Biol. 2024 Dec; 26(12):2144-2153.View Related Profiles. PMID: 39448802
     
  5. Ewoldt JK, Wang MC, McLellan MA, Cloonan PE, Chopra A, Gorham J, Li L, DeLaughter DM, Gao X, Lee JH, Willcox JAL, Layton O, Luu RJ, Toepfer CN, Eyckmans J, Seidman CE, Seidman JG, Chen CS. Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling. Sci Adv. 2024 Oct 18; 10(42):eadi6927.View Related Profiles. PMID: 39413182; PMCID: PMC11482324; DOI: 10.1126/sciadv.adi6927;
     
  6. Natarajan A, Kim S, Moreno GH, Eyckmans J, Chen CS, Dean D, Vijayan VM. 3D printing assisted surface patterning process on acrylated hydrogels for contact guidance of fibroblasts. Colloids Surf B Biointerfaces. 2024 Oct; 242:114099.View Related Profiles. PMID: 39024719
     
  7. Gagnon KA, Huang J, Hix OT, Hui VW, Hinds A, Bullitt E, Eyckmans J, Kotton DN, Chen CS. Multicompartment duct platform to study epithelial-endothelial crosstalk associated with lung adenocarcinoma. APL Bioeng. 2024 Jun; 8(2):026126.View Related Profiles. PMID: 38911024; PMCID: PMC11191334; DOI: 10.1063/5.0207228;
     
  8. Lammers A, Hsu HH, Sundaram S, Gagnon KA, Kim S, Lee JH, Tung YC, Eyckmans J, Chen CS. Rapid Tissue Perfusion Using Sacrificial Percolation of Anisotropic Networks. Matter. 2024 Jun 05; 7(6):2184-2204.View Related Profiles. PMID: 39221109; PMCID: PMC11360881; DOI: 10.1016/j.matt.2024.04.001;
     
  9. He S, Mierke CT, Sun Y, Eyckmans J, Guo M. Editorial: Mechanobiology of organoid systems. Front Cell Dev Biol. 2024; 12:1369713. PMID: 38352858; PMCID: PMC10861786; DOI: 10.3389/fcell.2024.1369713;
     
  10. Li L, Griebel ME, Uroz M, Bubli SY, Gagnon KA, Trappmann B, Baker BM, Eyckmans J, Chen CS. A Protein-Adsorbent Hydrogel with Tunable Stiffness for Tissue Culture Demonstrates Matrix-Dependent Stiffness Responses. Adv Funct Mater. 2024 Apr 25; 34(17).View Related Profiles. PMID: 38693998; PMCID: PMC11060701; DOI: 10.1002/adfm.202309567;
     
Showing 10 of 52 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 50 publications over 20 distinct years, with a maximum of 8 publications in 2024

YearPublications
20051
20062
20081
20091
20101
20114
20121
20132
20141
20151
20162
20174
20183
20195
20201
20215
20222
20233
20248
20252

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610 Commonwealth Ave
Boston MA 02215
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