Hee-Young Park | Profiles RNS

Hee-Young Park, PhD

Professor

Boston University School of Medicine

Dept of Medical Sciences & Education

PhD, Massachusetts Institute of Technology

Pronouns: she/her/hers

Websites

	ResearchGate
	LinkedIn
	Medical Sciences & Education Department

ORCID : 0000-0001-8981-6484

Dr. Hee-Young Park is a Professor and Chair of Medical Sciences & Education department at BUSM. She additional holds an administrative role as the Associate Dean of Faculty Affairs and oversees the faculty appointments and promotions at BUSM, as well as many other faculty related activities. Dr. Park received both B.S. and Ph.D. degrees from MIT and spent first 2 decades of her professional career as a biomedical researcher. Dr. Park’s research was focused on signaling pathways and factors that control skin color, aging and cutaneous wound healing. Specifically, she has made seminal contribution in these fields by discovering and characterizing the key role of serine/threonine kinases that turn on and off key enzymes and transcription factors. In addition to her research activities, she has consulted cosmetic and pharmaceutical companies interested in developing treatments for pigmentation-disorders and holds a patent for a method to decrease skin pigmentation. Dr. Park also has a long-standing interest in teaching and mentoring students. She has served as a faculty advisor and mentor to graduate students, medical students, residents and post-doctoral fellows.

Professor
Boston University School of Medicine
Dermatology
Dermatology (excluding Mohs Surgery)

Associate Dean for Faculty Affairs
Boston University School of Medicine
Dean’s Office

Chair
Boston University School of Medicine
Medical Sciences & Education

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

The Ability of Dermagraft to Stimulate Proliferation of Dermal Fibroblasts and Suppress Growth Inhibitory Activity of Chronic Wound Fluid
08/03/2004 - 02/28/2006 (PI)
Smith & Nephew

Proposal for Phase V Study
05/01/2001 - 12/31/2003 (PI)
Augustine Medical Devices Inc

Activation of Tyrosinase in Human Melanogenesis
03/15/1997 - 12/31/2001 (PI)
NIH/National Cancer Institute
5 R01 CA72763 04

The Effects of the Augustine Medical Wound Care Device on the Inhibitory Effects of Chronic Wound Fluid Upon Fibroblasts In Vitro.
09/01/1996 - 04/30/2001 (PI)
Augustine Medical Inc (formerly Augustine Medical Devices Inc)

Title

Yr	Title	Project-Sub Proj	Pubs
2004	CHRONIC WOUND FLUID EFFECTS ON CELL CYCLE PROTEIN	5P41RR010888-08-140	259
2000	ACTIVATION OF TYROSINASE IN HUMAN MELANOGENESIS	5R01CA072763-04	7
1999	ACTIVATION OF TYROSINASE IN HUMAN MELANOGENESIS	5R01CA072763-03	7
1998	ACTIVATION OF TYROSINASE IN HUMAN MELANOGENESIS	5R01CA072763-02	7
1998	ACTIVATION OF TYROSINASE IN HUMAN MELANOGENESIS	3R01CA072763-02S1	7
1997	ACTIVATION OF TYROSINASE IN HUMAN MELANOGENESIS	5P41RR010888-02-45	259
1997	ACTIVATION OF TYROSINASE IN HUMAN MELANOGENESIS	1R01CA072763-01A1	7

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Park HY, Berkowitz O, Symes K, Dasgupta S. The art and science of selecting graduate students in the biomedical sciences: Performance in doctoral study of the foundational sciences. PLoS One. 2018; 13(4):e0193901.View Related Profiles.

Park, Hee-Young
Symes, Karen
Berkowitz, Oren
Dasgupta, Shoumita

PMID: 29614110; PMCID: PMC5882097; DOI: 10.1371/journal.pone.0193901;

Mitchell B, Leone D, Feller JK, Bondzie P, Yang S, Park HY, Mahalingam M. Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with established histopathologic prognosticators and the BRAF status. Melanoma Res. 2014 Dec; 24(6):621-5.View Related Profiles.

Park, Hee-Young
Mahalingam, Meera
Bondzie, Philip Apraku
Yang, Shi

PMID: 25211166; DOI: 10.1097/CMR.0000000000000120;

Belisle ES, Park HY. Metformin: a potential drug to treat hyperpigmentation disorders. J Invest Dermatol. 2014 Oct; 134(10):2488-91. PMID: 25219649; DOI: 10.1038/jid.2014.245;

Mitchell B, Leone D, Feller K, Menon S, Bondzie P, Yang S, Park HY, Mahalingam M. Protein expression of the chemokine receptor CXCR4 and its ligand CXCL12 in primary cutaneous melanoma--biomarkers of potential utility? Hum Pathol. 2014 Oct; 45(10):2094-100.View Related Profiles.

Park, Hee-Young
Mahalingam, Meera
Bondzie, Philip Apraku
Menon, Sandeep
Yang, Shi

PMID: 25130395; DOI: 10.1016/j.humpath.2014.06.018;

Bae-Harboe YS, Park HY. Tyrosinase: a central regulatory protein for cutaneous pigmentation. J Invest Dermatol. 2012 Dec; 132(12):2678-80. PMID: 23187110; DOI: 10.1038/jid.2012.324;

Yaar M, Park HY. Melanocytes: a window into the nervous system. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):835-45.View Related Profiles.

Park, Hee-Young
Yaar, Mina

PMID: 22158549; DOI: 10.1038/jid.2011.386;

Park HY, Kim JH, Ji JH, Ahn SK, Hong SP. Variant of phacomatosis pigmentokeratotica. J Dermatol. 2011 Jul; 38(7):719-22. PMID: 21352309; DOI: 10.1111/j.1346-8138.2010.01069.x;

Byers HR, Boissel SJ, Tu C, Park HY. RNAi-mediated knockdown of protein kinase C-alpha inhibits cell migration in MM-RU human metastatic melanoma cell line. Melanoma Res. 2010 Jun; 20(3):171-8. PMID: 20216103; DOI: 10.1097/CMR.0b013e32832f1581;

Park HY, Wu C, Yaar M, Stachur CM, Kosmadaki M, Gilchrest BA. Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes. Int J Cell Biol. 2009; 2009:750482.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young
Yaar, Mina

PMID: 20130821; PMCID: PMC2814237; DOI: 10.1155/2009/750482;

Park HY, Kosmadaki M, Yaar M, Gilchrest BA. Cellular mechanisms regulating human melanogenesis. Cell Mol Life Sci. 2009 May; 66(9):1493-506.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young
Yaar, Mina

PMID: 19153661; DOI: 10.1007/s00018-009-8703-8;

Showing 10 of 25 results. Show More

Yaar M, Wu C, Park HY, Panova I, Schutz G, Gilchrest BA. Bone morphogenetic protein-4, a novel modulator of melanogenesis. J Biol Chem. 2006 Sep 1; 281(35):25307-14.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young
Yaar, Mina

PMID: 16837459

Park HY, Wu C, Yonemoto L, Murphy-Smith M, Wu H, Stachur CM, Gilchrest BA. MITF mediates cAMP-induced protein kinase C-beta expression in human melanocytes. Biochem J. 2006 May 1; 395(3):571-8.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 16411896; PMCID: PMC1462691; DOI: 10.1042/BJ20051388;

Kim EJ, Park HY, Yaar M, Gilchrest BA. Modulation of vascular endothelial growth factor receptors in melanocytes. Exp Dermatol. 2005 Aug; 14(8):625-33.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young
Yaar, Mina

PMID: 16026585

Seah CC, Phillips TJ, Howard CE, Panova IP, Hayes CM, Asandra AS, Park HY. Chronic wound fluid suppresses proliferation of dermal fibroblasts through a Ras-mediated signaling pathway. J Invest Dermatol. 2005 Feb; 124(2):466-74.View Related Profiles.

Park, Hee-Young
Phillips, Tania

PMID: 15675969

Park HY, Wu H, Killoran CE, Gilchrest BA. The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-beta on melanosomes. J Cell Sci. 2004 Jul 15; 117(Pt 16):3659-68.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 15252133

Park HY, Lee J, González S, Middelkamp-Hup MA, Kapasi S, Peterson S, Gilchrest BA. Topical application of a protein kinase C inhibitor reduces skin and hair pigmentation. J Invest Dermatol. 2004 Jan; 122(1):159-66.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 14962104

Park HY, Gilchrest BA. More on MITF. J Invest Dermatol. 2002 Dec; 119(6):1218-9.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 12485419

40. J.D. Raffetto, M. Leverkus, H.Y. Park and J.O. Menzoian . Synopsis on cellular senescence and apoptosis. 2001; 34:173-177.

Park HY, Gilchrest BA. Signaling pathways mediating melanogenesis. Cell Mol Biol (Noisy-le-grand). 1999 Nov; 45(7):919-30.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 10643996

Park HY, Perez JM, Laursen R, Hara M, Gilchrest BA. Protein kinase C-beta activates tyrosinase by phosphorylating serine residues in its cytoplasmic domain. J Biol Chem. 1999 Jun 4; 274(23):16470-8.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 10347209

Phillips TJ, Al-Amoudi HO, Leverkus M, Park HY. Effect of chronic wound fluid on fibroblasts. J Wound Care. 1998 Nov 02; 7(10):527-532.View Related Profiles.

Park, Hee-Young
Phillips, Tania

PMID: 27957893

Park HY, Russakovsky V, Ao Y, Fernandez E, Gilchrest BA. Alpha-melanocyte stimulating hormone-induced pigmentation is blocked by depletion of protein kinase C. Exp Cell Res. 1996 Aug 25; 227(1):70-9.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 8806453

Park HY, Gilchrest BA. Protein kinase C: biochemical characteristics and role in melanocyte biology. J Dermatol Sci. 1993 Dec; 6(3):185-93.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 8136316

Park HY, Russakovsky V, Ohno S, Gilchrest BA. The beta isoform of protein kinase C stimulates human melanogenesis by activating tyrosinase in pigment cells. J Biol Chem. 1993 Jun 5; 268(16):11742-9.View Related Profiles.

Gilchrest, Barbara
Park, Hee-Young

PMID: 7685020

Park HY, Campisi J. Posttranslational control of cyclic AMP-dependent protein kinase by phorbol ester in normal but not in chemically transformed 3T3 cells. Cancer Res. 1990 Nov 15; 50(22):7145-52. PMID: 2171757

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 25 publications over 16 distinct years, with a maximum of 3 publications in 2014