Clint Makino, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Pharmacology, Physiology & Biophysics

PhD, Florida State University - Tallahassee
BS, Duke University



Dr. Clint Makino completed his PhD at Florida State University and postdoctoral studies at Stanford University School of Medicine. He is currently Professor of Pharmacology, Physiology and Biophysics at Chobanian and Avedisian School of Medicine. He has published more than 50 journal papers and book chapters and serves on the editorial board of Frontiers in Molecular Neuroscience.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Rod outer segment structure: determinants and its effect on the photon response
09/01/2020 - 06/30/2025 (PI)
NIH/National Eye Institute
5R01EY031702-04

Bridging across scales to model cone phototransduction
08/01/2018 - 07/31/2021 (Subcontract PI)
Vanderbilt University National Science Fdn
DMS-1812601

Modulation of Visual Transduction and Retinal Disease by Bicarbonate
05/01/2016 - 03/31/2019 (PI)
NIH/National Eye Institute
5R01EY023980-05



Title


Yr Title Project-Sub Proj Pubs
2023 Rod outer segment structure: determinants and its effect on the photon response 5R01EY031702-04
2022 Rod outer segment structure: determinants and its effect on the photon response 3R01EY031702-02S1
2022 Rod outer segment structure: determinants and its effect on the photon response 5R01EY031702-03
2021 Rod outer segment structure: determinants and its effect on the photon response 5R01EY031702-02
2020 Rod outer segment structure: determinants and its effect on the photon response 1R01EY031702-01
2017 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 5R01EY023980-05 5
2016 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 5R01EY023980-04 5
2015 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 7R01EY023980-03 5
2015 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 5R01EY023980-02 5
2014 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 1R01EY023980-01A1 5
Showing 10 of 30 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Adhikari RD, Kossoff AM, Cornwall MC, Makino CL. Bicarbonate boosts flash response amplitude to augment absolute sensitivity and extend dynamic range in murine retinal rods. Front Mol Neurosci. 2023; 16:1125006.View Related Profiles. PMID: 37122625; PMCID: PMC10140344; DOI: 10.3389/fnmol.2023.1125006;
     
  2. Sharma RK, Pandey KN, Duda T, Makino CL. Editorial: Multi-limbed membrane guanylate cyclase cellular signaling pathways. Front Mol Neurosci. 2023; 16:1185637. PMID: 37122624; PMCID: PMC10130573; DOI: 10.3389/fnmol.2023.1185637;
     
  3. Caruso G, Klaus C, Hamm HE, Gurevich VV, Bisegna P, Andreucci D, DiBenedetto E, Makino CL. Pepperberg plot: Modeling flash response saturation in retinal rods of mouse. Front Mol Neurosci. 2022; 15:1054449. PMID: 36710929; PMCID: PMC9880052; DOI: 10.3389/fnmol.2022.1054449;
     
  4. Geva P, Caruso G, Klaus C, Hamm HE, Gurevich VV, DiBenedetto E, Makino CL. Effects of cell size and bicarbonate on single photon response variability in retinal rods. Front Mol Neurosci. 2022; 15:1050545.View Related Profiles. PMID: 36590910; PMCID: PMC9796569; DOI: 10.3389/fnmol.2022.1050545;
     
  5. Klaus C, Caruso G, Gurevich VV, Hamm HE, Makino CL, DiBenedetto E. Phototransduction in retinal cones: Analysis of parameter importance. PLoS One. 2021; 16(10):e0258721. PMID: 34710119; PMCID: PMC8553137; DOI: 10.1371/journal.pone.0258721;
     
  6. Caruso G, Klaus CJ, Hamm HE, Gurevich VV, Makino CL, DiBenedetto E. Position of rhodopsin photoisomerization on the disk surface confers variability to the rising phase of the single photon response in vertebrate rod photoreceptors. PLoS One. 2020; 15(10):e0240527. PMID: 33052986; PMCID: PMC7556485; DOI: 10.1371/journal.pone.0240527;
     
  7. Caruso G, Gurevich VV, Klaus C, Hamm H, Makino CL, DiBenedetto E. Local, nonlinear effects of cGMP and Ca2+ reduce single photon response variability in retinal rods. PLoS One. 2019; 14(12):e0225948. PMID: 31805112; PMCID: PMC6894879; DOI: 10.1371/journal.pone.0225948;
     
  8. Makino CL, Duda T, Pertzev A, Isayama T, Geva P, Sandberg MA, Sharma RK. Modes of Accessing Bicarbonate for the Regulation of Membrane Guanylate Cyclase (ROS-GC) in Retinal Rods and Cones. eNeuro. 2019 Jan-Feb; 6(1).View Related Profiles. PMID: 30783616; PMCID: PMC6378327; DOI: 10.1523/ENEURO.0393-18.2019;
     
  9. Makino CL, Duda T, Pertzev A, Sharma RK. Experimental Approaches for Defining the Role of the Ca2+-Modulated ROS-GC System in Retinal Rods of Mouse. Methods Mol Biol. 2018; 1753:129-158. PMID: 29564786
     
  10. Sharma RK, Duda T, Makino CL. Integrative Signaling Networks of Membrane Guanylate Cyclases: Biochemistry and Physiology. Front Mol Neurosci. 2016; 9:83. PMID: 27695398; PMCID: PMC5023690; DOI: 10.3389/fnmol.2016.00083;
     
Showing 10 of 58 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 58 publications over 32 distinct years, with a maximum of 4 publications in 2006 and 2012

YearPublications
19811
19841
19871
19903
19911
19942
19951
19962
19971
19992
20001
20013
20022
20031
20043
20052
20064
20071
20081
20093
20101
20111
20124
20143
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20162
20181
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20201
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20233


1998 Florida State University: Distinguished Alumnus Award
1989 FASEB Young Investigator Award
1982-1987 Patricia Roberts Harris Fellowship
Contact for Mentoring:

700 Albany Street
Boston MA 02118
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