Clint Makino, PhD
Associate Professor
Boston University School of Medicine
Dept of Physiology & Biophysics

PhD, Florida State University - Tallahassee




Dr. Clint Makino completed his PhD at Florida State University and postdoctoral studies at Stanford University School of Medicine. He is currently an Associate Professor of Physiology and Biophysics at Boston University School of Medicine. He has published more than 50 journal papers and book chapters and serves on the editorial board of Frontiers in Molecular Neuroscience.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



1998 Florida State University: Distinguished Alumnus Award
1989 FASEB Young Investigator Award
1982-1987 Patricia Roberts Harris Fellowship


Bridging across scales to model cone phototransduction
08/01/2018 - 07/31/2021 (Subcontract PI)
Vanderbilt University National Science Fdn
DMS-1812601

Modulation of Visual Transduction and Retinal Disease by Bicarbonate
05/01/2016 - 03/31/2019 (PI)
NIH/National Eye Institute
5R01EY023980-05



Title


Yr Title Project-Sub Proj Pubs
2017 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 5R01EY023980-05 5
2016 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 5R01EY023980-04 5
2015 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 5R01EY023980-02 5
2015 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 7R01EY023980-03 5
2014 Modulation of Visual Transduction and Retinal Disease by Bicarbonate 1R01EY023980-01A1 5
2011 Multiple Ligand Binding Sites of Rod and Cone Opsins 5R01EY011358-14 18
2010 Multiple Ligand Binding Sites of Rod and Cone Opsins 5R01EY011358-13 18
2009 Multiple Ligand Binding Sites of Rod and Cone Opsins 5R01EY011358-12 18
2009 Multiple Ligand Binding Sites of Rod and Cone Opsins 3R01EY011358-11S1 18
2008 Multiple Ligand Binding Sites of Rod and Cone Opsins 5R01EY011358-11 18
Showing 10 of 25 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Caruso G, Gurevich VV, Klaus C, Hamm H, Makino CL, DiBenedetto E. Local, nonlinear effects of cGMP and Ca2+ reduce single photon response variability in retinal rods. PLoS One. 2019; 14(12):e0225948. PMID: 31805112
     
  2. Makino CL, Duda T, Pertzev A, Isayama T, Geva P, Sandberg MA, Sharma RK. Modes of Accessing Bicarbonate for the Regulation of Membrane Guanylate Cyclase (ROS-GC) in Retinal Rods and Cones. eNeuro. 2019 Jan-Feb; 6(1).View Related Profiles. PMID: 30783616
     
  3. Makino CL, Duda T, Pertzev A, Sharma RK. Experimental Approaches for Defining the Role of the Ca2+-Modulated ROS-GC System in Retinal Rods of Mouse. Methods Mol Biol. 2018; 1753:129-158. PMID: 29564786
     
  4. Sharma RK, Duda T, Makino CL. Integrative Signaling Networks of Membrane Guanylate Cyclases: Biochemistry and Physiology. Front Mol Neurosci. 2016; 9:83. PMID: 27695398
     
  5. Duda T, Pertzev A, Makino CL, Sharma RK. Bicarbonate and Ca(2+) Sensing Modulators Activate Photoreceptor ROS-GC1 Synergistically. Front Mol Neurosci. 2016; 9:5. PMID: 26858600; PMCID: PMC4729890
     
  6. Duda T, Wen XH, Isayama T, Sharma RK, Makino CL. Bicarbonate Modulates Photoreceptor Guanylate Cyclase (ROS-GC) Catalytic Activity. J Biol Chem. 2015 Apr 24; 290(17):11052-60. PMID: 25767116; PMCID: PMC4409265
     
  7. Sharma RK, Baehr W, Makino CL, Duda T. Ca(2+) and Ca(2+)-interlocked membrane guanylate cyclase signal modulation of neuronal and cardiovascular signal transduction. Front Mol Neurosci. 2015; 8:7. PMID: 25798085; PMCID: PMC4351612
     
  8. Isayama T, Chen Y, Kono M, Fabre E, Slavsky M, DeGrip WJ, Ma JX, Crouch RK, Makino CL. Coexpression of three opsins in cone photoreceptors of the salamander Ambystoma tigrinum. J Comp Neurol. 2014 Jul 01; 522(10):2249-65. PMID: 24374736; PMCID: PMC3997598
     
  9. Wen XH, Dizhoor AM, Makino CL. Membrane guanylyl cyclase complexes shape the photoresponses of retinal rods and cones. Front Mol Neurosci. 2014; 7:45. PMID: 24917784; PMCID: PMC4040495
     
  10. Sharma RK, Makino CL, Hicks D, Duda T. ROS-GC interlocked Ca(2+)-sensor S100B protein signaling in cone photoreceptors: review. Front Mol Neurosci. 2014; 7:21. PMID: 24723847; PMCID: PMC3972482
     
Showing 10 of 52 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 52 publications over 28 distinct years, with a maximum of 4 publications in 2006 and 2012

YearPublications
19811
19841
19871
19903
19911
19942
19951
19962
19971
19992
20001
20013
20022
20031
20043
20052
20064
20071
20081
20093
20101
20111
20124
20143
20152
20162
20181
20192

Contact for Mentoring:

700 Albany Street
Boston MA 02118
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