Chun Shao | Profiles RNS

Chun Shao, PhD

Senior Scientist

Bristol Myers Squibb

Websites

	LinkedIn
	ResearchGate

ORCID : 0000-0003-0855-2320

Other Positions
Publications

Predoctoral Trainee (previously held)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Biochemistry & Cell Biology

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Chen L, Lin W, Le Z, Wan F, Zhang H, Geng S, Huang Q, Gao J, Hu W, Chen H, Liu X, Shao C, Su F, Lu JJ, Kong L. Carbon ion combined photon radiotherapy induces ferroptosis via NCOA4-mediated ferritinophagy in glioblastoma. Redox Biol. 2025 Oct; 86:103865. PMID: 40925125; PMCID: PMC12450722; DOI: 10.1016/j.redox.2025.103865;

Hua Y, Song H, Deng H, Tian H, Liu C, Wu H, Wang S, Shao C, Ye L, Ge S, Leong KW, Yu J, Ruan J. A senescence-responsive nanodrug amplifies radiotherapy efficacy. J Control Release. 2025 Nov 10; 387:114202. PMID: 40921255

Zhao C, Su BJ, Lin WZ, He AF, Hui DY, Liu HL, Chen H, Xiao MY, Chen JN, Li HF, Zheng JY, Wang WJ, Huang Y, Shao CK. An emerging entity of gastric adenocarcinoma: clinicopathological features and differential diagnosis of gastric adenocarcinoma of fundic-gland type in 25 retrospective cases. Virchows Arch. 2025 Mar 18. PMID: 40100386

Yu J, Deng J, Ren L, Hua L, Wu T, Hui Y, Shao C, Gong Y. A high content clonogenic survival drug screening identifies maytansine as a potent radiosensitizer for meningiomas. Front Immunol. 2025; 16:1557165. PMID: 40170861; PMCID: PMC11959303; DOI: 10.3389/fimmu.2025.1557165;

Liu D, Wang H, Yang W, Bai Y, Wu Z, Cui T, Bian K, Yi J, Shao C, Zhang B. One-Dose Bioorthogonal Gadolinium Nanoprobes for Prolonged Radiosensitization of Tumor. Small. 2025 Apr; 21(15):e2500504. PMID: 40059485

Zhou Y, Zeng L, Cai L, Zheng W, Liu X, Xiao Y, Jin X, Bai Y, Lai M, Li H, Jiang H, Hu S, Pan Y, Zhang J, Shao C. Cellular senescence-associated gene IFI16 promotes HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma. Nat Commun. 2025 Jan 31; 16(1):1212. PMID: 39890789; PMCID: PMC11785807; DOI: 10.1038/s41467-025-56456-y;

Liu X, Song Y, Hu S, Bai Y, Zhang J, Tai G, Shao C, Pan Y. Serum amyloid A contributes to radiation-induced lung injury by activating macrophages through FPR2/Rac1/NF-?B pathway. Int J Biol Sci. 2024; 20(12):4941-4956. PMID: 39309438; PMCID: PMC11414394; DOI: 10.7150/ijbs.100823;

Hu W, Ma SL, Qiong L, Du Y, Gong LP, Pan YH, Sun LP, Wen JY, Chen JN, Guan XY, Shao CK. PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma. iScience. 2024 Mar 15; 27(3):109116. PMID: 38384839; PMCID: PMC10879691; DOI: 10.1016/j.isci.2024.109116;

Wang H, Chen J, Zhang X, Sheng X, Chang XY, Chen J, Chen MS, Dong H, Duan GJ, Hu HP, Huang ZY, Jia WD, Jiang XQ, Kuang D, Li SS, Li ZS, Lu CL, Qin SK, Qiu XS, Qu LJ, Shao CK, Shen F, Shi GM, Shi SS, Shi YJ, Sun HC, Teng XD, Wang B, Wang ZB, Wen TF, Yang JM, Yang QQ, Ye SL, Yin HF, Yuan ZG, Yun JP, Zang FL, Zhang HQ, Zhang LH, Zhao JM, Zhou J, Zhou WX, Fan J, Chen XP, Lau WY, Ji Y, Cong WM. Expert Consensus on Pathological Diagnosis of Intrahepatic Cholangiocarcinoma (2022 version). J Clin Transl Hepatol. 2023 Dec 28; 11(7):1553-1564. PMID: 38161496; PMCID: PMC10752808; DOI: 10.14218/JCTH.2023.00118;

Shi X, Yang Y, Zhang W, Wang J, Xiao D, Ren H, Wang T, Gao F, Liu Z, Zhou K, Li P, Zhou Z, Zhang P, Shen X, Liu Y, Zhao J, Wang Z, Liu F, Shao C, Wu D, Zhang H. FLASH X-ray spares intestinal crypts from pyroptosis initiated by cGAS-STING activation upon radioimmunotherapy. Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43):e2208506119. PMID: 36256824

Showing 10 of 48 results. Show More

Luan H, Zhang X, Ding H, Zhang F, Luan JH, Jiao ZB, Yang YC, Bu H, Wang R, Gu J, Shao C, Yu Q, Shao Y, Zeng Q, Chen N, Liu CT, Yao KF. High-entropy induced a glass-to-glass transition in a metallic glass. Nat Commun. 2022 Apr 21; 13(1):2183. PMID: 35449135

Zhao C, Guan JX, Hui DY, Zhang NN, Lu LR, Tang LY, Shao CK, Chen JN. Liver involvement in patients with erythropoietic protoporphyria: retrospective analysis of clinicopathological features of 5 cases. Ann Diagn Pathol. 2022 Feb; 56:151859. PMID: 34844099

He YD, Tao W, He T, Wang BY, Tang XM, Zhang LM, Wu ZQ, Deng WM, Zhang LX, Shao CK, Zhou J, Rong LM, Gao X, Li LY. A urine extracellular vesicle circRNA classifier for detection of high-grade prostate cancer in patients with prostate-specific antigen 2-10 ng/mL at initial biopsy. Mol Cancer. 2021 Jul 23; 20(1):96. PMID: 34301266

Pan H, Song Y, Zhang H, Bai Y, Konishi T, Kobayashi A, Shao C, Pan Y. Radiation engenders converse migration and invasion in colorectal cancer cells through opposite modulation of ANXA2/AKT/GSK3ß pathway. Am J Cancer Res. 2021; 11(1):61-78. PMID: 33520360

Jiang YQ, Cao SE, Cao S, Chen JN, Wang GY, Shi WQ, Deng YN, Cheng N, Ma K, Zeng KN, Yan XJ, Yang HZ, Huan WJ, Tang WM, Zheng Y, Shao CK, Wang J, Yang Y, Chen GH. Preoperative identification of microvascular invasion in hepatocellular carcinoma by XGBoost and deep learning. J Cancer Res Clin Oncol. 2021 Mar; 147(3):821-833. PMID: 32852634

Chen F, Zhang Y, Hu S, Shi X, Wang Z, Deng Z, Lin L, Zhang J, Pan Y, Bai Y, Liu F, Zhang H, Shao C. TIGAR/AP-1 axis accelerates the division of Lgr5- reserve intestinal stem cells to reestablish intestinal architecture after lethal radiation. Cell Death Dis. 2020 Jul 06; 11(7):501. PMID: 32632140

Wasalathanthri DP, Rehmann MS, Song Y, Gu Y, Mi L, Shao C, Chemmalil L, Lee J, Ghose S, Borys MC, Ding J, Li ZJ. Technology outlook for real-time quality attribute and process parameter monitoring in biopharmaceutical development-A review. Biotechnol Bioeng. 2020 10; 117(10):3182-3198. PMID: 32946122; DOI: 10.1002/bit.27461;

Zhu L, Chen Q, Zhang L, Hu S, Zheng W, Wang C, Bai Y, Pan Y, Konishi T, Guan J, Shao C. CLIC4 regulates radioresistance of nasopharyngeal carcinoma by iNOS after ?-rays but not carbon ions irradiation. Am J Cancer Res. 2020; 10(5):1400-1415. PMID: 32509387

Tian XP, Su N, Wang L, Huang WJ, Liu YH, Zhang X, Huang HQ, Lin TY, Ma SY, Rao HL, Li M, Liu F, Zhang F, Zhong LY, Liang L, Lan XL, Li J, Liao B, Li ZH, Tang QL, Liang Q, Shao CK, Zhai QL, Cheng RF, Sun Q, Ru K, Gu X, Lin XN, Yi K, Shuang YR, Chen XD, Dong W, Sun C, Sang W, Liu H, Zhu ZG, Rao J, Guo QN, Zhou Y, Meng XL, Zhu Y, Hu CL, Jiang YR, Zhang Y, Gao HY, He WJ, Xia ZJ, Pan XY, Hai L, Li GW, Song LY, Kang TB, Xie D, Cai QQ. A CpG Methylation Classifier to Predict Relapse in Adults with T-Cell Lymphoblastic Lymphoma. Clin Cancer Res. 2020 Jul 15; 26(14):3760-3770. PMID: 32234760

Tian XP, Xie D, Huang WJ, Ma SY, Wang L, Liu YH, Zhang X, Huang HQ, Lin TY, Rao HL, Li M, Liu F, Zhang F, Zhong LY, Liang L, Lan XL, Li J, Liao B, Li ZH, Tang QL, Liang Q, Shao CK, Zhai QL, Cheng RF, Sun Q, Ru K, Gu X, Lin XN, Yi K, Shuang YR, Chen XD, Dong W, Sang W, Sun C, Liu H, Zhu ZG, Rao J, Guo QN, Zhou Y, Meng XL, Zhu Y, Hu CL, Jiang YR, Zhang Y, Gao HY, He WJ, Xia ZJ, Pan XY, Lan H, Li GW, Liu L, Bao HZ, Song LY, Kang TB, Cai QQ. A gene-expression-based signature predicts survival in adults with T-cell lymphoblastic lymphoma: a multicenter study. Leukemia. 2020 Sep; 34(9):2392-2404. PMID: 32080345

Dong C, Tu W, He M, Fu J, Kobayashi A, Konishi T, Shao C. Role of Endoplasmic Reticulum and Mitochondrion in Proton Microbeam Radiation-Induced Bystander Effect. Radiat Res. 2020 Jan; 193(1):63-72. PMID: 31714866

De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Gru Nwald-Grube C, Shao C, Zaia J, Evers W, Pengelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt NC, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pucic-Bakovic M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr TD, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang S, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee JY, Yoo JS, Kim SR, Suh SK, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer NH, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli PE, Kasper BT, Mahal L, Harvey DJ, O'Flaherty R, Rudd PM, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo C, Reiz B, Whittal RM, Lebrilla CB, Wu L, Guttman A, Szigeti M, Kremkow BG, Lee KH, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois YN, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, Stein SE. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics. 2020 01; 19(1):11-30.View Related Profiles.

Shao, Chun
Zaia, Joseph

PMID: 31591262; PMCID: PMC6944243; DOI: 10.1074/mcp.RA119.001677;

Jacobsen Á, Shi X, Shao C, Eysturskard J, Mikalsen SO, Zaia J. Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass Spectrometry. ACS Omega. 2019 Sep 24; 4(13):15337-15347.View Related Profiles.

Shao, Chun
Zaia, Joseph

PMID: 31572832; PMCID: PMC6761683; DOI: 10.1021/acsomega.9b01136;

Yang Z, Gu Q, Wang Y, Liu B, Zhou G, Shao C, Ruan J, Jia R, Ge S. Heavy-Ion Carbon Radiation Regulates Long Non-Coding RNAs in Cervical Cancer HeLa Cells. J Cancer. 2019; 10(21):5022-5030. PMID: 31602253

Tian XP, Huang WJ, Huang HQ, Liu YH, Wang L, Zhang X, Lin TY, Rao HL, Li M, Liu F, Zhang F, Zhong LY, Liang L, Lan XL, Li J, Liao B, Li ZH, Tang QL, Liang Q, Shao CK, Zhai QL, Cheng RF, Sun Q, Ru K, Gu X, Lin XN, Yi K, Shuang YR, Chen XD, Dong W, Sang W, Sun C, Liu H, Zhu ZG, Rao J, Guo QN, Zhou Y, Meng XL, Zhu Y, Hu CL, Jiang YR, Zhang Y, Gao HY, He WJ, Xia ZJ, Wu CL, Zhang MY, Wang HY, Xie D, Cai QQ. Prognostic and predictive value of a microRNA signature in adults with T-cell lymphoblastic lymphoma. Leukemia. 2019 Oct; 33(10):2454-2465. PMID: 30953029

Tu W, Dong C, Fu J, Pan Y, Kobayashi A, Furusawa Y, Konishi T, Shao C. Both irradiated and bystander effects link with DNA repair capacity and the linear energy transfer. Life Sci. 2019 Apr 01; 222:228-234. PMID: 30858123

Chen JN, Zhou L, Qiu XM, Yang RH, Liang J, Pan YH, Li HF, Peng GR, Shao CK. Determination and genome-wide analysis of Epstein-Barr virus (EBV) sequences in EBV-associated gastric carcinoma from Guangdong, an endemic area of nasopharyngeal carcinoma. J Med Microbiol. 2018 Nov; 67(11):1614-1627. PMID: 30239329

Wu C, Ning H, Liu M, Lin J, Luo S, Zhu W, Xu J, Wu WC, Liang J, Shao CK, Ren J, Wei B, Cui J, Chen MS, Zheng L. Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis. J Clin Invest. 2018 Aug 01; 128(8):3425-3438. PMID: 29771686

Raghunathan R, Polinski NK, Klein JA, Hogan JD, Shao C, Khatri K, Leon D, McComb ME, Manfredsson FP, Sortwell CE, Zaia J. Glycomic and Proteomic Changes in Aging Brain Nigrostriatal Pathway. Mol Cell Proteomics. 2018 09; 17(9):1778-1787.View Related Profiles.

Shao, Chun
Zaia, Joseph
Khatri, Kshitij
McComb, Mark
Raghunathan, Rekha

PMID: 29915149; PMCID: PMC6126385; DOI: 10.1074/mcp.RA118.000680;

Ruan J, Wang Y, Li F, Jia R, Zhou G, Shao C, Zhu L, Cui M, Yang DP, Ge S. Graphene Quantum Dots for Radiotherapy. ACS Appl Mater Interfaces. 2018 May 02; 10(17):14342-14355. PMID: 29542912

Zhang Y, Chen JN, Dong M, Zhang ZG, Zhang YW, Wu JY, Du H, Li HG, Huang Y, Shao CK. Clinical significance of spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia in Epstein-Barr virus-associated and Epstein-Barr virus-negative gastric cancer. Hum Pathol. 2017 May; 63:128-138. PMID: 28300576

Gao X, Li LY, Rassler J, Pang J, Chen MK, Liu WP, Chen Z, Ren SC, Zhou FJ, Xie KJ, Zhou X, Qian HJ, Bai XZ, Liu JM, Yang JG, He D, Shao CK, Su ZL, Wang J, Qiu JG, Ling L. Prospective Study of CRMP4 Promoter Methylation in Prostate Biopsies as a Predictor For Lymph Node Metastases. J Natl Cancer Inst. 2017 Jan; 109(6). PMID: 28122909

Li J, Zhou Z, Zhang X, Zheng L, He D, Ye Y, Zhang QQ, Qi CL, He XD, Yu C, Shao CK, Qiao L, Wang L. Inflammatory Molecule, PSGL-1, Deficiency Activates Macrophages to Promote Colorectal Cancer Growth through NF?B Signaling. Mol Cancer Res. 2017 Apr; 15(4):467-477. PMID: 28108624

Zaia J, Khatri K, Klein J, Shao C, Sheng Y, Viner R. Complete Molecular Weight Profiling of Low-Molecular Weight Heparins Using Size Exclusion Chromatography-Ion Suppressor-High-Resolution Mass Spectrometry. Anal Chem. 2016 11 01; 88(21):10654-10660.View Related Profiles.

Shao, Chun
Zaia, Joseph
Khatri, Kshitij

PMID: 27709905; PMCID: PMC5111364; DOI: 10.1021/acs.analchem.6b03081;

Dierker T, Shao C, Haitina T, Zaia J, Hinas A, Kjellén L. Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans. Sci Rep. 2016 10 05; 6:34662.View Related Profiles.

Shao, Chun
Zaia, Joseph

PMID: 27703236; PMCID: PMC5050403; DOI: 10.1038/srep34662;

Dong M, Wang HY, Zhao XX, Chen JN, Zhang YW, Huang Y, Xue L, Li HG, Du H, Wu XY, Shao CK. Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus-associated gastric carcinoma. Hum Pathol. 2016 Jul; 53:25-34. PMID: 26980034

Tu W, Dong C, Konishi T, Kobayashi A, Furusawa Y, Uchihori Y, Xie Y, Dang B, Li W, Shao C. G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jan 01; 795:1-6. PMID: 26774662

Dong C, He M, Tu W, Konishi T, Liu W, Xie Y, Dang B, Li W, Uchihori Y, Hei TK, Shao C. The differential role of human macrophage in triggering secondary bystander effects after either gamma-ray or carbon beam irradiation. Cancer Lett. 2015 Jul 10; 363(1):92-100. PMID: 25896631; PMCID: PMC4428931

Shen ZC, Luo B, Chen JN, Chao Y, Shao CK, Liu QQ, Wang Y. High prevalence of the EBER variant EB-8m in endemic nasopharyngeal carcinomas. PLoS One. 2015; 10(3):e0121420. PMID: 25807550; PMCID: PMC4373760

He YD, Luo ZH, Yang M, Ruan XX, Liu SY, Wu ZQ, Deng WM, Shao CK, Su ZL, He D, Gao X, Li LY. Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder. Biochem Biophys Res Commun. 2015 Apr 10; 459(3):416-23. PMID: 25744029

Reine TM, Kolseth IB, Meen AJ, Lindahl JP, Jenssen TG, Reinholt FP, Zaia J, Shao C, Hartmann A, Kolset SO. Effects of restoring normoglycemia in type 1 diabetes on inflammatory profile and renal extracellular matrix structure after simultaneous pancreas and kidney transplantation. Diabetes Res Clin Pract. 2015 Jan; 107(1):46-53.View Related Profiles.

Shao, Chun
Zaia, Joseph

PMID: 25467621; PMCID: PMC4324617; DOI: 10.1016/j.diabres.2014.10.006;

Turiák L, Shao C, Meng L, Khatri K, Leymarie N, Wang Q, Pantazopoulos H, Leon DR, Zaia J. Workflow for combined proteomics and glycomics profiling from histological tissues. Anal Chem. 2014 Oct 7; 86(19):9670-8.View Related Profiles.

Shao, Chun
Zaia, Joseph
Khatri, Kshitij
Turiak, Lilla
Leymarie, Nancy
Wang, Qi

PMID: 25203838; PMCID: PMC4427244; DOI: 10.1021/ac5022216;

He M, Dong C, Konishi T, Tu W, Liu W, Shiomi N, Kobayashi A, Uchihori Y, Furusawa Y, Hei TK, Dang B, Shao C. Differential effects of p53 on bystander phenotypes induced by gamma ray and high LET heavy ion radiation. Life Sci Space Res (Amst). 2014 Apr; 1:53-9. PMID: 26432589

Dang B, Yang Y, Zhang E, Li W, Mi X, Meng Y, Yan S, Wang Z, Wei W, Shao C, Xing R, Lin C. Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts. Life Sci. 2014 Mar 03; 97(2):123-8. PMID: 24361401

Shao C, Shi X, Phillips JJ, Zaia J. Mass spectral profiling of glycosaminoglycans from histological tissue surfaces. Anal Chem. 2013 Nov 19; 85(22):10984-91.View Related Profiles.

Shao, Chun
Zaia, Joseph
Shi, Xiaofeng

PMID: 24099043; PMCID: PMC3872031; DOI: 10.1021/ac402517s;

Shi X, Shao C, Mao Y, Huang Y, Wu ZL, Zaia J. LC-MS and LC-MS/MS studies of incorporation of 34SO3 into glycosaminoglycan chains by sulfotransferases. Glycobiology. 2013 Aug; 23(8):969-79.View Related Profiles.

Shao, Chun
Zaia, Joseph
Shi, Xiaofeng
Mao, Yang
Huang, Yu

PMID: 23696150; PMCID: PMC3695753; DOI: 10.1093/glycob/cwt033;

Shao C, Shi X, White M, Huang Y, Hartshorn K, Zaia J. Comparative glycomics of leukocyte glycosaminoglycans. FEBS J. 2013 May; 280(10):2447-61.View Related Profiles.

Shao, Chun
Zaia, Joseph
Hartshorn, Kevan
Shi, Xiaofeng
Huang, Yu

PMID: 23480678; PMCID: PMC3651794; DOI: 10.1111/febs.12231;

Shao C, Folkard M, Michael BD, Prise KM. Targeted cytoplasmic irradiation induces bystander responses. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13495-500. PMID: 15345742; PMCID: PMC518785

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 48 publications over 14 distinct years, with a maximum of 6 publications in 2019 and 2020 and 2025

Bar chart showing 48 publications over 14 distinct years, with a maximum of 6 publications in 2019 and 2020 and 2025

Year	Publications
2004	1
2013	4
2014	3
2015	4
2016	3
2017	3
2018	4
2019	6
2020	6
2021	3
2022	2
2023	1
2024	2
2025	6

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