Christos Mantzoros, MD, DSc, PhD
Adjunct Professor
Boston University School of Medicine
Dept of Medicine
General Internal Medicine

MD, University of Athens
MMS/MMSc, Harvard Medical School
MSc, Harvard School of Public Health
DSc, University of Athens

Christos S. Mantzoros, MD, DSc, PhD h.c. mult., is a Professor of Medicine at Harvard Medical School and an Adjunct Professor at Boston University School of Medicine. He has also served as a Professor of Environmental Health at the Harvard School of Public Health. He currently serves as the Chief of Endocrinology, Diabetes and Metabolism at the Boston VA Healthcare System and the Director of the Human Nutrition Unit of the Division of Endocrinology Diabetes and Metabolism at Beth Israel Deaconess Medical Center. Dr. Mantzoros has been the editor of two books (one on “Diabetes and Obesity” and one on “Nutrition and Metabolism” with more than two editions each). His research has resulted in more than 800 publications in Medline, including more than 150 publications under the collaborative Look Ahead Research Group, more than 200 chapters and reviews, with more than 72,000 citations with a Hirsch Index H=121. Dr. Mantzoros is also the director for the VA Boston Healthcare System fellowship program with Boston University Medical Center (BUMC), which offers one dedicated fellowship position through BUMC, but also allows any fellow at BUMC or Harvard affiliated fellowship programs the opportunity to rotate through the VA Boston Healthcare System. He has served as a Board Member or an advisor or head of the Scientific Advisor Board of non for profit foundations as well as governmental and non-governmental entities. He is the Editor-in-Chief of the journal Metabolism and is on the editorial board of several scientific journals worldwide. For his research discoveries and public health service Dr. Mantzoros has received four honorary PhDs, the Alexander Technological Institute of Thessaloniki has named their nutrition laboratories after his name and several Universities worldwide have awarded Dr. Mantzoros honorary Professorships and visiting Professorships. He has or is supervising PhD thesis work in several nations worldwide (Sweden, Germany, Greece, USA etc) and is actively collaborating with many research groups worldwide. He has mentored more than 160 young scientists who currently hold key positions in clinical medicine, academia, industry as well as governmental agencies and nongovernmental organizations. Dr. Mantzoros has been elected a member of ASCI and a Fellow of the American College of Physicians and the American Association of Clinical Endocrinology. He has been given several awards including but not limited to awards by: the American Association of Clinical Endocrinology (Frontiers in Science Award), the American Diabetes Association (Novartis Award in Diabetes and Metabolic Diseases), the North American Association for the Study of Obesity / the Obesity Society (Lilly Award), the American Society for Nutrition (Mead Johnson Award), the HypoCCS award in Paris, France, the Humboldt Foundation of Germany (the Wilhelm Friedrich Bessel Award), by the American Federation of Medical Research (the Outstanding Investigator Award), by the American Physiological Society (FASEB, the Berson Award Lecture), by the New England Hellenic Medical and Dental Association (Hygeia award) etc. He has also received the BIDMC, Harvard Medical School, award for excellence in Mentoring. He will be receiving the 2018 European Society of Endocrinology Geoffrey Harris Prize.

Harvard Medical School

Beth Israel Deaconess Medical Center
Endocrinology, Diabetes, and Metabolism
Human Nutrition Unit

VA Boston Healthcare System

Lorcaserin in Obesity: Identification of CNS Targets Using fMRI

Yr Title Project-Sub Proj Pubs
2020 Adipokine physiology 5K24DK081913-10 96
2019 Adipokine physiology 5K24DK081913-09 96
2018 Adipokine physiology 5K24DK081913-08 96
2017 Adipokine physiology 5K24DK081913-07 96
2016 Adipokine physiology 2K24DK081913-06A1 96
2014 Leptin Signaling in Humans 5I01CX000422-04 19
2013 Leptin Signaling in Humans 5I01CX000422-03 19
2012 Leptin Signaling in Humans 5I01CX000422-02 19
2012 Leptin and Adipokine Physiology 5K24DK081913-05 96
2012 The Role of Leptin in the Maintenance of a Reduced Body Weight 5R01DK079929-05 67
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Novak V, Mantzoros CS, Novak P, McGlinchey R, Dai W, Lioutas V, Buss S, Fortier CB, Khan F, Aponte Becerra L, Ngo LH. MemAID: Memory advancement with intranasal insulin vs. placebo in type 2 diabetes and control participants: a randomized clinical trial. J Neurol. 2022 Apr 28.View Related Profiles. PMID: 35482079; PMCID: PMC9046533; DOI: 10.1007/s00415-022-11119-6;
  2. Polyzos SA, Mantzoros CS. Metreleptin for the treatment of lipodystrophy: leading the way among novel therapeutics for this unmet clinical need. Curr Med Res Opin. 2022 Apr 12; 1-4. PMID: 35352624
  3. Kouvari M, Polyzos SA, Chrysohoou C, Skoumas J, Pitsavos CS, Panagiotakos DB, Mantzoros CS. Skeletal muscle mass and abdominal obesity are independent predictors of hepatic steatosis and interact to predict ten-year cardiovascular disease incidence: Data from the ATTICA cohort study. Clin Nutr. 2022 Mar 31; 41(6):1281-1289. PMID: 35504171
  4. Kouvari M, Tsiampalis T, Chrysohoou C, Georgousopoulou E, Skoumas J, Mantzoros CS, Pitsavos CS, Panagiotakos DB. Quality of plant-based diets in relation to 10-year cardiovascular disease risk: the ATTICA cohort study. Eur J Nutr. 2022 Mar 05. PMID: 35249127
  5. Markozannes G, Ntzani EE, Tsapas A, Mantzoros CS, Tsiara S, Xanthos T, Karpettas N, Patrikios I, Rizos EC. Dose-related meta-analysis for Omega-3 fatty acids supplementation on major adverse cardiovascular events. Clin Nutr. 2022 Apr; 41(4):923-930. PMID: 35290840
  6. Perakakis N, Kalra B, Angelidi AM, Kumar A, Gavrieli A, Yannakoulia M, Mantzoros CS. Methods paper: Performance characteristics of novel assays for circulating levels of proglucagon-derived peptides and validation in a placebo controlled cross-over randomized clinical trial. Metabolism. 2022 04; 129:155157. PMID: 35114286
  7. Angelidi AM, Papadaki A, Nolen-Doerr E, Boutari C, Mantzoros CS. The effect of dietary patterns on non-alcoholic fatty liver disease diagnosed by biopsy or magnetic resonance in adults: a systematic review of randomised controlled trials. Metabolism. 2022 04; 129:155136.View Related Profiles. PMID: 35032545
  8. Sanoudou D, Hill MA, Belanger MJ, Arao K, Mantzoros CS. Editorial: Obesity, metabolic phenotypes and COVID-19. Metabolism. 2022 03; 128:155121. PMID: 35026232; PMCID: PMC8743503; DOI: 10.1016/j.metabol.2021.155121;
  9. Valanti EK, Dalakoura-Karagkouni K, Fotakis P, Vafiadaki E, Mantzoros CS, Chroni A, Zannis V, Kardassis D, Sanoudou D. Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK. Metabolism. 2022 02; 127:154954.View Related Profiles. PMID: 34875308
  10. Kollari E, Zografou I, Sampanis C, Athyros VG, Didangelos T, Mantzoros CS, Karagiannis A. Serum adipokine levels in patients with type 1 diabetes are associated with degree of obesity but only resistin is independently associated with atherosclerosis markers. Hormones (Athens). 2022 Mar; 21(1):91-101. PMID: 34716910
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