Christos S. Mantzoros, MD, DSc, PhD h.c. mult. is a Professor of Medicine at Harvard Medical School. He has also served as a Professor of Environmental Health at the Harvard School of Public Health and Professor of Medicine at the Boston University School of Medicine.

He currently serves as the Chief of Endocrinology, Diabetes and Metabolism at the Boston VA Healthcare System, where he created a leading academic division true to its tripartite mission. He also serves as the Director of Human Nutrition which he had created at Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School. He has performed groundbreaking research in several areas of nutrition and metabolism, he sees patients himself, runs a clinical group and has developed clinical programs, he has grown people’s careers, he has co-founded companies and published patents and he has presented endowed lectures and received awards at national and international meetings. Importantly, he is an active clinical endocrinologist practicing in the outpatient (two clinics per week) and inpatient settings including covering the call service. The clinical division he created for the VA Boston Healthcare System has expanded tremendously and covers several hospitals and clinic locations, is affiliated with Harvard, Boston University and Univ. of Massachusetts Medical Schools, and brings together in terms of clinical and education all VA endocrinologists up to the Canadian borders.

Dr. Mantzoros has received enormous recognition in the field. As some indices of his success to date, Dr. Mantzoros has published more than 1100 scientific papers i.e. 775 publications under his name in Medline in addition to more than 220 publications under the collaborative Look Ahead Research Group and more than 310 chapters and reviews or editorials. His corpus has received more than 168,800 citations with an H-index of 157 and an i10 index of 631 (Google Scholar).

Dr. Mantzoros has published as an editor two books (one on “Diabetes and Obesity” and one on “Nutrition and Metabolism” with more than two editions each). He currently edits the journal Metabolism (2023 2-year impact factor 10.8; 4-year Cite Score 20.5, top 2% of all journals, in contrast to 2-year impact factor of 2 and lowest 20% when Dr. Mantzoros was appointed editor in chief). He is on the editorial board of several scientific journals and has served as guest editor of many journal supplements. He has also presented more than 500 abstracts at national and international meetings. He has given faculty presentations to over 500 local, national, or international meetings. He sits on multiple local and national committees and is a sought after speaker who is frequently speaking as faculty in major national and international scientific meetings. Additionally, he has been a guest to a number of local or national media programs.

An outstanding active clinician and prolific clinical investigator, Dr. Mantzoros has run many projects, more than 135 clinical trials and has trained and mentored in clinical trials, in the laboratory, in the clinics, and beyond, a large number of people who have gone on to successful careers in academia. Dr. Mantzoros has mentored medical students as the Fellow of the Canon Society of Harvard Medical School, Master’s level students enrolled in the Scholars in Clinical Science Program at Harvard Medical School, Fellows as the BIDMC Endocrinology Associate Fellowship Program Director, Faculty members as the Chief of Endocrinology at the Boston VA Healthcare System and has been a successful mentor with an active network of over 185 former/current mentees who trained in his Laboratory. Among the latter are 16 full Professors, numerous Associate and Assistant Professors, several Executives at pharmaceutical companies, three corporate CEOs, one Chief Scientific Officer and two Chief Medical Officers. He has received competitive NIH awards for mentoring and has received recognition and awards from BIDMC, Harvard Medical School, and various professional and academic societies nationally and internationally.

He has or is supervising PhD thesis work in several nations worldwide (USA, Sweden, Germany, Greece, etc.) and is actively collaborating with many research groups worldwide. He has served as Associate Fellowship Program Director at BIDMC and later as Endocrinology, Diabetes and Metabolism Fellowship Program Founding and Site Director at the Boston VA Healthcare System. He has taught courses at the undergraduate level, at the Medical School and at the postgraduate level and has directed and organized or co-organized several CME courses. He has not only taught but has also designed and/or organized training programs for medical trainees, pharmacy students and nursing students

Based on his many seminal contributions to the respective scientific fields, Dr. Mantzoros has been ranked as number 1 in the world in leptin and/or adipokine research, number 2 in adiponectin research, and in the top 0.1% of experts on obesity and NASH on ExpertScape, which objectively ranks scientists and institutions by expertise in more than 27,000 biomedical topics. He is also among the highest 1% of cited investigators in terms of citations and H index and has been named Highly Cited Researcher by Clarivate for the years 2020, 2021, 2022 and 2023. He has applied for approximately 20 patents and has received several while others are still pending, has co-founded successful companies and has served as a board member, an advisor, or head of the scientific advisory boards of non-profit foundations as well as government and state agencies or commissions as well as for-profit private businesses and non-profit entities. He has served on the Board of Trustees of Hellenic College in Boston and is currently on the Board of ALBA Graduate Business School, the American College of Greece, a Massachusetts based Institution.

For his research discoveries, clinical contributions and public health service, Dr. Mantzoros has received four honorary PhDs, four honorary professorships, and several visiting professorships across the world and the International Hellenic University has named their Clinical Nutrition Laboratories after him.

Dr. Mantzoros has been elected a member of ASCI and a Fellow of the American College of Physicians and the American Association of Clinical Endocrinology. He has been given several awards including but not limited to: the Frontiers in Science Award by the American Association of Clinical Endocrinology, the Novartis Award in Diabetes and Metabolic Diseases by the American Diabetes Association, the Lilly Award by the North American Association for the Study of Obesity/the Obesity Society, the Mead Johnson Award by the American Society for Nutrition, the HypoCCS award in Paris, France, the Wilhelm Friedrich Bessel Award by the Humboldt Foundation of Germany, the Outstanding Investigator Award by the American Federation of Medical Research, the Hygeia award by the New England Hellenic Medical and Dental Association, the Berson Award Lecture by the American Physiological Society (FASEB) and several named Award Lectures worldwide, amongst many others. He has also received the BIDMC and Harvard Medical School award for Excellence in Mentoring.

Most recently, he has received several prestigious awards for his lifetime achievements: the 2017 Obesity Society TOPS Award, the 2018 Endocrine Society Outstanding Clinical Investigator Award, the 2018 European Society of Endocrinology Geoffrey Harris Prize, and the 2018 American Society of Nutrition’s Robert H. Herman Award, the 2020 American Society of Nutrition’s E. V. McCollum Award, the 2020 Gerald Reaven Distinguished Leader in Insulin Resistance Award by the World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease, the 2021 Greek College of Internal Medicine Hippocrates award and the Korean Society of Nutrition Award co-administered with the American Society for Nutrition, and the 2025 Endocrine Society Outstanding Scholarly Physician Award, as life achievement awards. He has also given several Named and Endowed Lectures worldwide

Dr. Mantzoros created two active laboratories where he performs basic and translational research and has participated in or solely performed many clinical trials (more than 135). He has been funded by the NIH since 1996, and has received many grants (more than 75) from the NIH, Dept. of Defense, Foundations, Industry etc. over his 26 years of service after fellowship, resulting in $26.5M in direct costs and more than $40 million in direct and indirect costs for his own projects and an estimated more than another $50 million for collaborative projects. His most recent funding through the MLSC program of the State of Massachusetts exceeds $4 million over five years, his clinical trials and industry funding exceeds $2 million over two years. Beyond his VA clinical salary, for the past three decades, his and his team’s academic salaries and his work have almost exclusively been supported by external funding. The academic institutions involved invested less than 1% of the overhead they received for equipment purchases, for his teams’ salaries and fringe benefits or Laboratory or other expenses, and no other institutional contributions have been made towards any start up packages or salaries of any team members, faculty or trainees, or towards any research, teaching and education, infrastructure or any other expenses.