Brooke Nichols | Profiles RNS

Brooke Nichols, PhD

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Global Health

PhD, Erasmus Universiteit Rotterdam
MS, University of Massachusetts Amherst
BA, Mount Holyoke College

Pronouns: she/her/hers

Websites

	School of Public Health Faculty
	Health Economics and Epidemiology Research Office
	HIV Economics and Epidemiology Profile
	ResearchGate
	Google Scholar
	Twitter

ORCID : 0000-0003-4682-4999

Brooke Nichols, PhD, MSc, is an infectious disease mathematical modeller and health economist specializing in transmission dynamics, implementation modeling, and optimal resource allocation for pathogens including HIV, tuberculosis, SARS-CoV-2, and other pathogens of pandemic potential. Her work seeks to minimize the health and economic impact of infectious diseases through innovative quantitative approaches.

Dr. Nichols leads a multi-continental research team of quantitative scientists and modellers who integrate insights from clinical science, epidemiology, health economics, and mathematical modeling to develop actionable, evidence-based strategies. Her team advances novel quantitative methods and adapts existing frameworks to design cost-effective, scalable interventions aimed at reducing transmission, morbidity, and mortality. Their work has significantly influenced national and global health policies across critical public health domains. This includes contributing to evidence to normative guidance on HIV prevention and care (e.g., optimizing pre-exposure prophylaxis, scaling up HIV self-testing, improving viral load monitoring, and enhancing differentiated service delivery models), informing global strategies for the optimal use of diagnostics during the SARS-CoV-2 pandemic (spanning mitigation, treatment, and surveillance), and guiding the development of World Health Organization’s Target Product Profiles (TPPs) for innovative diagnostics.

BU Research

Innovative linkage strategies for index HIVST
12/03/2019 - 07/31/2024 (PI of Sub-Project / SP)
University of California, Los Angeles Bill & Melinda Gates

Scaling facility-based HIV self-testing
06/01/2019 - 11/30/2020 (Subcontract PI)
Clinton Health Access Initiative, Inc. Dept for Intl Dev-UK

Specimen transportation route mapping and optimisation: South Africa
02/01/2019 - 12/31/2019 (Subcontract PI)
The Health Economics and Epidemiology Research Office (HE2RO) HHS CDC

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website Copy PMIDs To Clipboard

de Nooy A, Miller C, Ockhuisen T, Falzon D, Korobitsyn A, Ruhwald M, Ismail N, Kohli M, Nichols BE. Guiding the development of the tuberculosis screening target product profile using single-screen and multi-screen approaches: a modelling study. Lancet Glob Health. 2025 Oct; 13(10):e1750-e1760. PMID: 40975082; DOI: 10.1016/S2214-109X(25)00244-X;

Boer NA, Emperador DM, Eckerle I, Agogo E, Nichols BE. Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study. BMC Infect Dis. 2025 Sep 25; 25(1):1122. PMID: 40999340; PMCID: PMC12465612; DOI: 10.1186/s12879-025-11273-y;

Masuku SD, Nattey C, Coetzee L, Hirasen K, Mabhula A, Casalme DJ, Gler MT, Gupta A, Juneja S, Ndjeka N, Evans D, Nichols BE. An economic analysis of BPaL for multidrug-resistant TB in South Africa and the Philippines. IJTLD Open. 2025 Sep; 2(9):535-541. PMID: 40959787; PMCID: PMC12435464; DOI: 10.5588/ijtldopen.25.0294;

de Nooy A, Omar SV, Ockhuisen T, Zwerling A, Shrestha S, Suresh A, Khan S, Colman RE, Uplekar S, Rodwell TC, Ismail N, Grantz K, Girdwood S, Nichols BE. Cost-effectiveness of Targeted Next Generation Sequencing for TB drug-resistance testing as an alternative to the standard of care in South Africa. Clin Infect Dis. 2025 Sep 08. PMID: 40920587; DOI: 10.1093/cid/ciaf495;

Huber AN, Jamieson L, Fox MP, Manganye M, Malala L, Chidarikire T, Khoza N, Nichols BE, Rosen S, Pascoe S. Evaluating the impact of differentiated service delivery (DSD) on retention in care and HIV viral suppression in South Africa: A target trial emulation using routine healthcare data. PLoS Med. 2025 Aug; 22(8):e1004489.View Related Profiles.

Nichols, Brooke
Fox, Matthew
Rosen, Sydney

PMID: 40857347; PMCID: PMC12410879; DOI: 10.1371/journal.pmed.1004489;

Bezuidenhout C, Long L, Nichols B, Meyer-Rath G, Fox MP, Olifant S, Theron G, Fiphaza K, Pieruccini M, Ruhwald M, Penn-Nicholson A, Fourie B, Medina-Marino A. Using sputum and tongue swab specimens for in-home point-of-care targeted universal testing for tuberculosis of household contacts: an acceptability and feasibility analysis. BMJ Glob Health. 2025 Aug 21; 10(8).View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine
Long, Lawrence
Fox, Matthew

PMID: 40840972; PMCID: PMC12374641; DOI: 10.1136/bmjgh-2024-018131;

Benade M, Maskew M, Chilembo P, Wa Mwansa M, Savory T, Nichols B, Bolton C, Mulenga LB, Sivile S, Zyambo KD, Rosen S. Patterns of engagement in care during clients' first 12 months after HIV treatment initiation in Zambia: a retrospective cohort analysis using routinely collected data. BMJ Glob Health. 2025 Aug 11; 10(8).View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 40789714; PMCID: PMC12352237; DOI: 10.1136/bmjgh-2024-017930;

Benade M, Maskew M, Ntjikelane V, Scott N, Ngcobo N, Nichols B, Malala L, Manganye M, Rosen S. Prior antiretroviral therapy exposure among clients presenting for HIV treatment initiation in South Africa: an exploratory mixed-methods study using multiple indicators of exposure. BMC Infect Dis. 2025 Jul 26; 25(1):947.View Related Profiles.

Nichols, Brooke
Scott, Nancy
Rosen, Sydney

PMID: 40713520; PMCID: PMC12296601; DOI: 10.1186/s12879-025-11340-4;

Bezuidenhout C, Long L, Nichols B, Meyer-Rath G, Fox MP, Theron G, Fourie B, Olifant S, Penn-Nicholson A, Ruhwald M, Medina-Marino A. Sputum and tongue swab molecular testing for the in-home diagnosis of tuberculosis in unselected household contacts: a cost and cost-effectiveness analysis. Clin Infect Dis. 2025 Jul 24.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine
Long, Lawrence
Fox, Matthew

PMID: 40705837; DOI: 10.1093/cid/ciaf389;

Lekodeba NA, Rosen S, Phiri B, Masuku SD, Govathson C, Kamanga A, Haimbe P, Shakwelele H, Mwansa M, Lumano-Mulenga P, Huber AN, Pascoe SJS, Jamieson L, Nichols BE. Cost and effectiveness of differentiated ART service delivery strategies in Zambia: a modelling analysis using routine data. J Int AIDS Soc. 2025 Jul; 28(7):e70003.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 40579870; PMCID: PMC12205209; DOI: 10.1002/jia2.70003;

Showing 10 of 139 results. Show More

Chevalier JM, Grantz KH, Girdwood S, Kepha S, Ramos T, Nichols BE, Khan S, Hingel S. The impact and cost of a new rapid diagnostic test for school-based prevalence mapping and monitoring and evaluation surveys of schistosomiasis: A modelling study. PLoS Negl Trop Dis. 2025 May; 19(5):e0013071. PMID: 40354436; PMCID: PMC12097705; DOI: 10.1371/journal.pntd.0013071;

Chevalier JM, Hansen MA, Blumel B, Chuchu V, Gleeson B, Ferreyra C, Khan S, Nichols BE, Grantz KH. Modeling the impact and cost of a culture-dependent molecular test for antimicrobial resistance in resource-limited settings. Clin Infect Dis. 2025 May 12. PMID: 40350685; DOI: 10.1093/cid/ciaf236;

Nichols BE, Dodge JL, Lee BP, Bhadelia N, Bor J. Medicaid cuts, mortality, and health-care expenditure in the USA. Lancet. 2025 May 17; 405(10491):1736.View Related Profiles.

Nichols, Brooke
Bor, Jacob
Bhadelia, Nahid

PMID: 40318689; DOI: 10.1016/S0140-6736(25)00761-5;

Birnie E, Vergouwe M, Appelman B, Biemond JJ, Heijmans J, Nichols BE, Wiersinga WJ, Popping S. Cost-effectiveness Analysis of Nirmatrelvir/Ritonavir for COVID-19 Among Individuals at High Risk: A Modeling Study. Open Forum Infect Dis. 2025 Apr; 12(4):ofaf187. PMID: 40256045; PMCID: PMC12006789; DOI: 10.1093/ofid/ofaf187;

Grantz KH, Girdwood S, Muriuki A, Carmona S, Nichols BE, Khan S. Assessing feasibility and effectiveness of point-of-care limited HPV genotype tests in cervical cancer screening: a modelling study. medRxiv. 2025. View Publication

Nichols BE, Geng EH, Moakley E, Phillips AN, Imai-Eaton JW, Stover J, Mudimu E, Grimsrud A. Rapid development of an online tracker to communicate the human impact of abruptly halting PEPFAR support. J Int AIDS Soc. 2025 Mar; 28(3):e26433. PMID: 40012206; PMCID: PMC11865335; DOI: 10.1002/jia2.26433;

Hendrickson C, Hirasen K, Mongwenyana C, Benade M, Bothma R, Smith C, Meyer J, Nichols BE, Long LC. Costs and outcomes of routine HIV oral pre-exposure prophylaxis implementation across different service delivery models and key populations in South Africa: a retrospective cohort study. Lancet HIV. 2025 Feb; 12(2):e130-e142.View Related Profiles.

Nichols, Brooke
Long, Lawrence

PMID: 39914894; PMCID: PMC12446606; DOI: 10.1016/S2352-3018(24)00295-9;

Jo Y, Rosen S, Nichols BE, Jamieson L, Lekodeba N, Horsburgh R. Integrated multi-month dispensing for HIV and hypertension in South Africa: A model of epidemiological impact and cost-effectiveness. J Int AIDS Soc. 2025 Feb; 28(2):e26413.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 39939799; PMCID: PMC12020916; DOI: 10.1002/jia2.26413;

Nichols BE, de Nooy A, Cassim N, Hans L, da Silva MP, Chetty K, Grantz KH, Han AX, Phillips AN, Jamieson L, Scott LE, Stevens WS. Ten-year health impact, economic impact and return on investment of the South African molecular diagnostics programme for HIV, tuberculosis and SARS-CoV-2. BMJ Glob Health. 2024 Dec 03; 9(12). PMID: 39631789; PMCID: PMC11624778; DOI: 10.1136/bmjgh-2024-015830;

Bezuidenhout C, Long L, Nichols B, Meyer-Rath G, Fox MP, Olifant S, Theron G, Fiphaza K, Ruhwald M, Penn-Nicholson A, Fourie B, Medina-Marino A. USING SPUTUM AND TONGUE SWAB SPECIMENS FOR IN-HOME POINT-OF-CARE TARGETED UNIVERSAL TESTING FOR TB OF HOUSEHOLD CONTACTS: AN ACCEPTABILITY AND FEASIBILITY ANALYSIS. medRxiv. 2024 Nov 02.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine
Long, Lawrence
Fox, Matthew

PMID: 39574838; PMCID: PMC11581095; DOI: 10.1101/2024.11.01.24316570;

Nichols, Brooke
Meyer-Rath, Gesine
Long, Lawrence
Fox, Matthew

PMID: 39484233; PMCID: PMC11527052; DOI: 10.1101/2024.10.18.24315746;

Hansen MA, Han AX, Chevalier JM, Klock E, Pandithakoralage H, Nooy A, Ockhuisen T, Girdwood SJ, Lekodeba NA, Khan S, Jenkins HE, Johnson CC, Sacks JA, Russell CA, Nichols BE. Cost-effectiveness of SARS-CoV-2 self-testing at routine gatherings to minimize community-level infections in lower-middle income countries: A mathematical modeling study. PLoS One. 2024; 19(10):e0311198.View Related Profiles.

Nichols, Brooke
Jenkins, Helen

PMID: 39365802; PMCID: PMC11451991; DOI: 10.1371/journal.pone.0311198;

Rosen S, Lekodeba N, Sande L, Nichols B. Letter to the Editor: "Cost-effectiveness and budget impact analysis of the implementation of differentiated service delivery models for HIV treatment in Mozambique: a modelling study": Resource reductions are not equal to cost savings. J Int AIDS Soc. 2024 Oct; 27(10):e26367.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 39406476; PMCID: PMC11479750; DOI: 10.1002/jia2.26367;

Gleeson B, Ferreyra C, Palamountain K, Jacob ST, Spotswood N, Kissoon N, Nisar YB, Fitzgerald F, Murless-Collins S, Okomo U, Cross JH, Molyneux E, Piriou E, Iloh KK, Santorino D, Goldfarb D, Stevenson A, Kirby R, Nichols BE, Blumel B, Kelly-Cirino C, Walsh T, Lloyd L, Liaghati-Mobarhan S. A call to bridge the diagnostic gap: diagnostic solutions for neonatal sepsis in low- and middle-income countries. BMJ Glob Health. 2024 Sep 10; 9(9). PMID: 39260829; PMCID: PMC11404204; DOI: 10.1136/bmjgh-2024-015862;

Broger T, Marx FM, Theron G, Marais BJ, Nicol MP, Kerkhoff AD, Nathavitharana R, Huerga H, Gupta-Wright A, Kohli M, Nichols BE, Muyoyeta M, Meintjes G, Ruhwald M, Peeling RW, Pai NP, Pollock NR, Pai M, Cattamanchi A, Dowdy DW, Dewan P, Denkinger CM. Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research. Lancet Glob Health. 2024 Jul; 12(7):e1184-e1191. PMID: 38876764

Nooy A, Ockhuisen T, Korobitsyn A, Khan SA, Ruhwald M, Ismail N, Kohli M, Nichols BE. Trade-offs between clinical performance and test accessibility in tuberculosis diagnosis: a multi-country modelling approach for target product profile development. Lancet Glob Health. 2024 Jul; 12(7):e1139-e1148. PMID: 38876761

Hansen MA, Nichols BE. Integration of sexual health and HIV services. Lancet HIV. 2024 Jul; 11(7):e429-e430. PMID: 38925730

Thorp M, Balakasi K, Khan S, Stillson C, van Oosterhout JJ, Nichols BE, Cornell M, Dovel K. Men's Satisfaction with General Health Services is Associated with Future Use of HIV Testing in Malawi: A Community-Representative Survey. AIDS Behav. 2024 Aug; 28(8):2639-2649. PMID: 38869760; PMCID: PMC11286645; DOI: 10.1007/s10461-024-04352-9;

Marbán-Castro E, Muhwava L, Kamau Y, Safary E, Rheeder P, Karsas M, Kemp T, Freitas J, Carrihill M, Dave J, Katambo D, Kimetto J, Allie R, Ndungu J, Sigwebela N, Akach D, Girdwood S, Erkosar B, Nichols BE, Haldane C, Vetter B, Shilton S. Implementation research: a protocol for two three-arm pragmatic randomised controlled trials on continuous glucose monitoring devices in people with type 1 diabetes in South Africa and Kenya. Trials. 2024 May 21; 25(1):331. PMID: 38773658; PMCID: PMC11107040; DOI: 10.1186/s13063-024-08132-7;

Ockhuisen T, de Nooy A, Jenkins HE, Han A, Russell CA, Khan S, Girdwood S, Ruhwald M, Kohli M, Nichols BE. Cost-effectiveness of diagnostic tools and strategies for the screening and diagnosis of tuberculosis disease and infection: a scoping review. BMJ Public Health. 2024 Jun; 2(1):e000276.View Related Profiles.

Nichols, Brooke
Jenkins, Helen

PMID: 40018193; PMCID: PMC11816851; DOI: 10.1136/bmjph-2023-000276;

Hansen MA, Lekodeba NA, Chevalier JM, Ockhuisen T, Del Rey-Puech P, Marban-Castro E, Martínez-Pérez GZ, Shilton S, Radzi Abu Hassan M, Getia V, Weinert-Mizuschima C, Tenorio Bezerra MI, Chala L, Leong R, Peregino R, Keller S, Spruijt I, Johnson CC, Girdwood SJ, Nichols BE. Cost of SARS-CoV-2 self-test distribution programmes by different modalities: a micro-costing study in five countries (Brazil, Georgia, Malaysia, Ethiopia and the Philippines). BMJ Open. 2024 Apr 17; 14(4):e078852. PMID: 38631825; PMCID: PMC11029185; DOI: 10.1136/bmjopen-2023-078852;

Chevalier JM, Hansen MA, Coskun E, Sy KTL, Drakes J, Dowling S, Williams A, Jenkins S, Amole C, Haimbe P, Mpasela F, Shakwelele H, Nichols BE. Cost-effectiveness of intervention combinations towards the elimination of vertical transmission of HIV in limited-resource settings: a mathematical modelling study. Lancet Glob Health. 2024 Mar; 12(3):e457-e466. PMID: 38365416

Leavitt SV, Rodriguez CA, Bouton TC, Horsburgh CR, Abel Zur Wiesch P, Nichols BE, White LF, Jenkins HE. Outcomes for people with TB by disease severity at presentation. Int J Tuberc Lung Dis. 2024 Mar 01; 28(3):142-147.View Related Profiles.

Nichols, Brooke
Horsburgh, C.
Jenkins, Helen
White, Laura
Bouton, Tara

PMID: 38454178; PMCID: PMC11075045; DOI: 10.5588/ijtld.23.0254;

Chevalier JM, Han AX, Hansen MA, Klock E, Pandithakoralage H, Ockhuisen T, Girdwood SJ, Lekodeba NA, de Nooy A, Khan S, Johnson CC, Sacks JA, Jenkins HE, Russell CA, Nichols BE. Impact and cost-effectiveness of SARS-CoV-2 self-testing strategies in schools: a multicountry modelling analysis. BMJ Open. 2024 Feb 27; 14(2):e078674.View Related Profiles.

Nichols, Brooke
Jenkins, Helen

PMID: 38417953; PMCID: PMC10900377; DOI: 10.1136/bmjopen-2023-078674;

de Jong SPJ, Felix Garza ZC, Gibson JC, van Leeuwen S, de Vries RP, Boons GJ, van Hoesel M, de Haan K, van Groeningen LE, Hulme KD, van Willigen HDG, Wynberg E, de Bree GJ, Matser A, Bakker M, van der Hoek L, Prins M, Kootstra NA, Eggink D, Nichols BE, Han AX, de Jong MD, Russell CA. Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation. Nat Commun. 2024 Jan 18; 15(1):591. PMID: 38238318; PMCID: PMC10796432; DOI: 10.1038/s41467-023-44668-z;

Han AX, Hannay E, Carmona S, Rodriguez B, Nichols BE, Russell CA. Estimating the potential impact and diagnostic requirements for SARS-CoV-2 test-and-treat programs. Nat Commun. 2023 Dec 02; 14(1):7981. PMID: 38042923; PMCID: PMC10693634; DOI: 10.1038/s41467-023-43769-z;

Songo J, Whitehead HS, Nichols BE, Makwaya A, Njala J, Phiri S, Hoffman RM, Dovel K, Phiri K, van Oosterhout JJ. Provider-led community antiretroviral therapy distribution in Malawi: Retrospective cohort study of retention, viral load suppression and costs. PLOS Glob Public Health. 2023; 3(9):e0002081. PMID: 37768889; PMCID: PMC10538660; DOI: 10.1371/journal.pgph.0002081;

Rodriguez CA, Leavitt SV, Bouton TC, Horsburgh CR, Zur Wiesch PA, Nichols B, Jenkins HE, White LF. Survival of people with untreated TB: effects of time, geography and setting. Int J Tuberc Lung Dis. 2023 Sep 01; 27(9):694-702.View Related Profiles.

Nichols, Brooke
Jenkins, Helen
White, Laura
Bouton, Tara

PMID: 37608480; PMCID: PMC10443783; DOI: 10.5588/ijtld.22.0668;

Hendrickson C, Hirasen K, Mongwenyana C, Benade M, Bothma R, Smith C, Meyer J, Nichols B, Long L. Costs and outcomes of routine HIV oral pre-exposure prophylaxis implementation across different service delivery models and key populations in South Africa. medRxiv. 2023 Aug 16.View Related Profiles.

Nichols, Brooke
Long, Lawrence

PMID: 37645864; PMCID: PMC10462215; DOI: 10.1101/2023.08.14.23294055;

Dovel K, Balakasi K, Phiri K, Shaba F, Offorjebe OA, Gupta SK, Wong V, Lungu E, Nichols BE, Masina T, Worku A, Hoffman R, Nyirenda M. Effect of index HIV self-testing for sexual partners of clients enrolled in antiretroviral therapy (ART) programs in Malawi: A randomized controlled trial. PLoS Med. 2023 Aug; 20(8):e1004270. PMID: 37540649; PMCID: PMC10403056; DOI: 10.1371/journal.pmed.1004270;

Dovel K, Balakasi K, Hubbard J, Phiri K, Nichols BE, Coates TJ, Kulich M, Chikuse E, Phiri S, Long LC, Hoffman RM, Choko AT. Identifying efficient linkage strategies for men (IDEaL): a study protocol for an individually randomised control trial. BMJ Open. 2023 Jul 12; 13(7):e070896.View Related Profiles.

Nichols, Brooke
Long, Lawrence

PMID: 37438067; PMCID: PMC10347494; DOI: 10.1136/bmjopen-2022-070896;

Popping S, Nichols BE, Appelman B, Biemond JJ, Vergouwe M, Rosendaal FR, van der Valk M, de Bree GJ, Wiersinga WJ, Birnie E. Health Outcomes and Cost-effectiveness of Monoclonal SARS-CoV-2 Antibodies as Pre-exposure Prophylaxis. JAMA Netw Open. 2023 Jul 03; 6(7):e2321985. PMID: 37410460; PMCID: PMC10326646; DOI: 10.1001/jamanetworkopen.2023.21985;

Meyer-Rath G, Hounsell RA, Pulliam JR, Jamieson L, Nichols BE, Moultrie H, Silal SP. The role of modelling and analytics in South African COVID-19 planning and budgeting. PLOS Glob Public Health. 2023; 3(7):e0001063.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 37399174; PMCID: PMC10317222; DOI: 10.1371/journal.pgph.0001063;

Govathson C, Long LC, Russell CA, Moolla A, Pascoe S, Nichols BE. A modelling framework for translating discrete choice experiment results into cost-effectiveness estimates: an application to designing tailored and scalable HIV and contraceptive services for adolescents in Gauteng, South Africa. J Int AIDS Soc. 2023 Jul; 26(7):e26124.View Related Profiles.

Nichols, Brooke
Long, Lawrence

PMID: 37463870; PMCID: PMC10354002; DOI: 10.1002/jia2.26124;

Claassen CW, Kafunda I, Mwango L, Shiyanda S, Stoebenau K, Gekanju-Toeque M, Lindsay B, Adebayo O, Sinjani M, Kaayunga C, Wa Banza PK, Mweebo K, Kancheya N, Musokotwane K, Mwila A, Monze N, Nichols BE, Blanco N, Lavoie MC, Watson DC, Hachaambwa L, Sheneberger R. Achieving HIV Epidemic Control and Improving Maternal Healthcare Services with Community-Based HIV Service Delivery in Zambia: Mixed-Methods Assessment of the SMACHT Project. AIDS Behav. 2023 Nov; 27(11):3571-3583. PMID: 37204561; PMCID: PMC11252556; DOI: 10.1007/s10461-023-04071-7;

Jamieson L, Van Schalkwyk C, Nichols BE, Meyer-Rath G, Silal S, Pulliam J, Blumberg L, Cohen C, Moultrie H, Jassat W. Differential in-hospital mortality and intensive care treatment over time: Informing hospital pathways for modelling COVID-19 in South Africa. PLOS Glob Public Health. 2023; 3(5):e0001073.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 37195977; PMCID: PMC10191304; DOI: 10.1371/journal.pgph.0001073;

Dovel KL, Hariprasad S, Hubbard J, Cornell M, Phiri K, Choko A, Abbott R, Hoffman R, Nichols B, Gupta S, Long L. Strategies to improve antiretroviral therapy (ART) initiation and early engagement among men in sub-Saharan Africa: A scoping review of interventions in the era of universal treatment. Trop Med Int Health. 2023 Jun; 28(6):454-465.View Related Profiles.

Nichols, Brooke
Long, Lawrence

PMID: 37132119; PMCID: PMC10354296; DOI: 10.1111/tmi.13880;

Lavoie MC, Blanco N, Mwango LK, Nichols BE, Whittington A, Lindsay B, Adebayo O, Mujansi M, Tembo K, Hachaambwa L, Mumba D, Musonda B, Claassen CW. Addressing the Need for a Preexposure Prophylaxis Monitoring and Evaluation Implementation Guide: Experience From Zambia. Glob Health Sci Pract. 2023 Apr 28; 11(2). PMID: 37116937; PMCID: PMC10141438; DOI: 10.9745/GHSP-D-22-00396;

Silal SP, Pulliam JRC, Meyer-Rath G, Jamieson L, Nichols BE, Norman J, Hounsell R, Mayet S, Kagoro F, Moultrie H. The National COVID-19 Epi Model (NCEM): Estimating cases, admissions and deaths for the first wave of COVID-19 in South Africa. PLOS Glob Public Health. 2023; 3(4):e0001070.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 37093784; PMCID: PMC10124849; DOI: 10.1371/journal.pgph.0001070;

Jo Y, Jamieson L, Phiri B, Grimsrud A, Mwansa M, Shakwelele H, Haimbe P, Mukumbwa-Mwenechanya M, Mulenga PL, Nichols BE, Rosen S. Attrition from HIV treatment after enrollment in a differentiated service delivery model: A cohort analysis of routine care in Zambia. PLoS One. 2023; 18(3):e0280748.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 36917568; PMCID: PMC10013882; DOI: 10.1371/journal.pone.0280748;

Benade M, Nichols BE, Fatti G, Kuchukhidze S, Takarinda K, Mabhena-Ngorima N, Grimwood A, Rosen S. Economic evaluation of a cluster randomized, non-inferiority trial of differentiated service delivery models of HIV treatment in Zimbabwe. PLOS Glob Public Health. 2023; 3(3):e0000493.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 36962960; PMCID: PMC10021451; DOI: 10.1371/journal.pgph.0000493;

Han AX, Girdwood SJ, Khan S, Sacks JA, Toporowski A, Huq N, Hannay E, Russell CA, Nichols BE. Strategies for Using Antigen Rapid Diagnostic Tests to Reduce Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Low- and Middle-Income Countries: A Mathematical Modelling Study Applied to Zambia. Clin Infect Dis. 2023 Feb 18; 76(4):620-630. PMID: 36208211; PMCID: PMC9619661; DOI: 10.1093/cid/ciac814;

Popping S, Versteegh L, Nichols BE, van de Vijver DAMC, van Sighem A, Reiss P, Geerlings S, Boucher CAB, Verbon A. Characteristics and short- and long-term direct medical costs among adults with timely and delayed presentation for HIV care in the Netherlands. PLoS One. 2023; 18(2):e0280877. PMID: 36753495; PMCID: PMC9907815; DOI: 10.1371/journal.pone.0280877;

Horsburgh CR, Jo Y, Nichols B, Jenkins HE, Russell CA, White LF. Contribution of Reinfection to Annual Rate of Tuberculosis Infection (ARI) and Incidence of Tuberculosis Disease. Clin Infect Dis. 2023 Feb 08; 76(3):e965-e972.View Related Profiles.

Nichols, Brooke
Horsburgh, C.
Jenkins, Helen
White, Laura

PMID: 35666515; PMCID: PMC10169390; DOI: 10.1093/cid/ciac451;

Girdwood S, Pandey M, Machila T, Warrier R, Gautam J, Mukumbwa-Mwenechanya M, Benade M, Nichols K, Shibemba L, Mwewa J, Mzyece J, Lungu P, Albert H, Nichols B, Choonga P. The integration of tuberculosis and HIV testing on GeneXpert can substantially improve access and same-day diagnosis and benefit tuberculosis programmes: A diagnostic network optimization analysis in Zambia. PLOS Glob Public Health. 2023; 3(1):e0001179. PMID: 36963019; PMCID: PMC10022337; DOI: 10.1371/journal.pgph.0001179;

Han AX, Toporowski A, Sacks JA, Perkins MD, Briand S, van Kerkhove M, Hannay E, Carmona S, Rodriguez B, Parker E, Nichols BE, Russell CA. SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programs. Nat Genet. 2023 Jan; 55(1):26-33. PMID: 36624344; PMCID: PMC9839449; DOI: 10.1038/s41588-022-01267-w;

Jamieson L, Rosen S, Phiri B, Grimsrud A, Mwansa M, Shakwelele H, Haimbe P, Mukumbwa-Mwenechanya M, Lumano-Mulenga P, Chiboma I, Nichols BE. How soon should patients be eligible for differentiated service delivery models for antiretroviral treatment? Evidence from a retrospective cohort study in Zambia. BMJ Open. 2022 Dec 22; 12(12):e064070.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 36549722; PMCID: PMC9772670; DOI: 10.1136/bmjopen-2022-064070;

de Jong SPJ, Felix Garza ZC, Gibson JC, Han AX, van Leeuwen S, de Vries RP, Boons GJ, van Hoesel M, de Haan K, van Groeningen LE, Hulme KD, van Willigen HDG, Wynberg E, de Bree GJ, Matser A, Bakker M, van der Hoek L, Prins M, Kootstra NA, Eggink D, Nichols BE, de Jong MD, Russell CA. Potential impacts of prolonged absence of influenza virus circulation on subsequent epidemics. medRxiv. 2022 Nov 16. PMID: 36415458; PMCID: PMC9681055; DOI: 10.1101/2022.02.05.22270494;

Jamieson L, Johnson LF, Nichols BE, Delany-Moretlwe S, Hosseinipour MC, Russell C, Meyer-Rath G. Relative cost-effectiveness of long-acting injectable cabotegravir versus oral pre-exposure prophylaxis in South Africa based on the HPTN 083 and HPTN 084 trials: a modelled economic evaluation and threshold analysis. Lancet HIV. 2022 Dec; 9(12):e857-e867.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 36356603; PMCID: PMC9708606; DOI: 10.1016/S2352-3018(22)00251-X;

Hendrickson C, Long LC, van Rensburg C, Claassen CW, Njelesani M, Moyo C, Mulenga L, O'Bra H, Russell CA, Nichols BE. The early-stage comprehensive costs of routine PrEP implementation and scale-up in Zambia. PLOS Glob Public Health. 2022; 2(11):e0001246.View Related Profiles.

Nichols, Brooke
Long, Lawrence

PMID: 36962684; PMCID: PMC10021804; DOI: 10.1371/journal.pgph.0001246;

Girdwood SJ, Crompton T, Cassim N, Olsen F, Sejake P, Diallo K, Berrie L, Chimhamhiwa D, Stevens W, Nichols B. Optimising courier specimen collection time improves patient access to HIV viral load testing in South Africa. Afr J Lab Med. 2022; 11(1):1725. PMID: 36337769; PMCID: PMC9634786; DOI: 10.4102/ajlm.v11i1.1725;

Thorp M, Balakasi KT, Mphande M, Robson I, Khan S, Stillson C, Doi N, Nichols BE, Dovel K. Factors associated with men's health facility attendance as clients and caregivers in Malawi: a community-representative survey. BMC Public Health. 2022 10 12; 22(1):1904. PMID: 36224573; PMCID: PMC9558411; DOI: 10.1186/s12889-022-14300-8;

Han AX, Hannay E, Carmona S, Rodriguez B, Nichols BE, Russell CA. Estimating the potential need and impact of SARS-CoV-2 test-and-treat programs with oral antivirals in low-and-middle-income countries. medRxiv. 2022 Oct 05. PMID: 36238715; PMCID: PMC9558441; DOI: 10.1101/2022.10.05.22280727;

Nichols BE, de Nooy A, Benade M, Balakasi K, Mphande M, Rao G, Claassen CW, Khan S, Stillson C, Russell CA, Doi N, Dovel K. Facility-based HIV self-testing strategies may substantially and cost-effectively increase the number of men and youth tested for HIV in Malawi: results from an individual-based mathematical model. J Int AIDS Soc. 2022 Oct; 25(10):e26020. PMID: 36251161; PMCID: PMC9575938; DOI: 10.1002/jia2.26020;

Bershteyn A, Jamieson L, Kim HY, Platais I, Milali MP, Mudimu E, Ten Brink D, Martin-Hughes R, Kelly SL, Phillips AN, Bansi-Matharu L, Cambiano V, Revill P, Meyer-Rath G, Nichols BE. Transmission reduction, health benefits, and upper-bound costs of interventions to improve retention on antiretroviral therapy: a combined analysis of three mathematical models. Lancet Glob Health. 2022 09; 10(9):e1298-e1306.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 35961353; PMCID: PMC9380252; DOI: 10.1016/S2214-109X(22)00310-2;

van der Straten K, Guerra D, van Gils MJ, Bontjer I, Caniels TG, van Willigen HDG, Wynberg E, Poniman M, Burger JA, Bouhuijs JH, van Rijswijk J, Olijhoek W, Liesdek MH, Lavell AHA, Appelman B, Sikkens JJ, Bomers MK, Han AX, Nichols BE, Prins M, Vennema H, Reusken C, de Jong MD, de Bree GJ, Russell CA, Eggink D, Sanders RW. Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron. Immunity. 2022 Sep 13; 55(9):1725-1731.e4. PMID: 35973428; PMCID: PMC9353602; DOI: 10.1016/j.immuni.2022.07.018;

Han AX, Toporowski A, Sacks JA, Perkins M, Briand S, van Kerkhove M, Hannay E, Carmona S, Rodriguez B, Parker E, Nichols BE, Russell CA. Low testing rates limit the ability of genomic surveillance programs to monitor SARS-CoV-2 variants: a mathematical modelling study. medRxiv. 2022 May 23. PMID: 35664998; PMCID: PMC9164450; DOI: 10.1101/2022.05.20.22275319;

Chevalier JM, Sy KTL, Girdwood SJ, Khan S, Albert H, Toporowski A, Hannay E, Carmona S, Nichols BE. Optimal use of COVID-19 Ag-RDT screening at border crossings to prevent community transmission: A modeling analysis. PLOS Glob Public Health. 2022; 2(5):e0000086. PMID: 36962136; PMCID: PMC10021421; DOI: 10.1371/journal.pgph.0000086;

Phillips AN, Bershteyn A, Revill P, Bansi-Matharu L, Kripke K, Boily MC, Martin-Hughes R, Johnson LF, Mukandavire Z, Jamieson L, Meyer-Rath G, Hallett TB, Ten Brink D, Kelly SL, Nichols BE, Bendavid E, Mudimu E, Taramusi I, Smith J, Dalal S, Baggaley R, Crowley S, Terris-Prestholt F, Godfrey-Faussett P, Mukui I, Jahn A, Case KK, Havlir D, Petersen M, Kamya M, Koss CA, Balzer LB, Apollo T, Chidarikire T, Mellors JW, Parikh UM, Godfrey C, Cambiano V. Cost-effectiveness of easy-access, risk-informed oral pre-exposure prophylaxis in HIV epidemics in sub-Saharan Africa: a modelling study. Lancet HIV. 2022 May; 9(5):e353-e362.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 35489378; PMCID: PMC9065367; DOI: 10.1016/S2352-3018(22)00029-7;

Perspectives on the use of modelling and economic analysis to guide HIV programmes in sub-Saharan Africa. Lancet HIV. 2022 Jul; 9(7):e517-e520. PMID: 35468318; DOI: 10.1016/S2352-3018(22)00035-2;

Felix Garza ZC, de Jong SPJ, Gibson J, Han AX, van Leeuwen S, de Vries RP, Boons G-J, van Hoesel M, de Haan K, van Groeningen L, van Wiligen HDG, Wynberg E, de Bree GJ, Master A, van der Hoek L, Prins M, Koostra NA, Eggink D, Nichols BE, de Jong MD, Russell CA. Impacts of the COVID-19 pandemic on future seasonal influenza epidemics. medRxiv. 2022. View Publication

Rosen S, Nichols B, Guthrie T, Benade M, Kuchukhidze S, Long L. Do differentiated service delivery models for HIV treatment in sub-Saharan Africa save money? Synthesis of evidence from field studies conducted in sub-Saharan Africa in 2017-2019. Gates Open Res. 2021; 5:177.View Related Profiles.

Nichols, Brooke
Long, Lawrence
Rosen, Sydney

PMID: 35310814; PMCID: PMC8907143; DOI: 10.12688/gatesopenres.13458.2;

Silal S, Pulliam J, Jamieson L, Nichols B, Moultrie H, Meyer-Rath G. The role of modelling in planning and budgeting for SA's COVID-19 response. South African Health Review. 2021. View Publication

Sy KTL, White LF, Nichols BE. Reproducible Science Is Vital for a Stronger Evidence Base During the COVID-19 Pandemic. Geogr Anal. 2021 Nov 16.View Related Profiles.

Nichols, Brooke
White, Laura

PMID: 34898694; PMCID: PMC8652901; DOI: 10.1111/gean.12314;

Nichols BE, Rosen S. Economic evaluations of differentiated service delivery should include savings and ancillary benefits, not only health system costs: authors' reply. AIDS. 2021 11 01; 35(13):2235-2236.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 34602596; DOI: 10.1097/QAD.0000000000003034;

Nichols BE, Sy KTL, Chevalier J, Hansen M, Benade M, Girdwood SJ, Han AX, Toporowski A, Huq N, Russell CA. Extended use case analysis for SARS-CoV-2 mitigation: phase 1 results from the ACT-Accelerator SARS-CoV-2 rapid antigen testing modeling consortium. FIND Diagnostics: ACT-Accelerator. 2021. View Publication

Jo Y, Rosen S, Sy KTL, Phiri B, Huber AN, Mwansa M, Shakwelele H, Haimbe P, Mwenechanya MM, Lumano-Mulenga P, Nichols BE. Changes in HIV treatment differentiated care uptake during the COVID-19 pandemic in Zambia: interrupted time series analysis. J Int AIDS Soc. 2021 10; 24 Suppl 6:e25808.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 34713620; PMCID: PMC8554218; DOI: 10.1002/jia2.25808;

Nichols BE, van der Valk M. Barriers to eliminating HIV transmission in England by 2030. Lancet Public Health. 2021 10; 6(10):e699-e700. PMID: 34563279; DOI: 10.1016/S2468-2667(21)00161-4;

Popping S, Kall M, Nichols BE, Stempher E, Versteegh L, van de Vijver DAMC, van Sighem A, Versteegh M, Boucher C, Delpech V, Verbon A. Quality of life among people living with HIV in England and the Netherlands: a population-based study. Lancet Reg Health Eur. 2021 Sep; 8:100177. PMID: 34557859; PMCID: PMC8454587; DOI: 10.1016/j.lanepe.2021.100177;

Claassen CW, Mumba D, Njelesani M, Nyimbili D, Mwango LK, Mwitumwa M, Mubanga E, Mulenga LB, Chisenga T, Nichols BE, Hendrickson C, Chitembo L, Okuku J, O'Bra H. Initial implementation of PrEP in Zambia: health policy development and service delivery scale-up. BMJ Open. 2021 07 09; 11(7):e047017. PMID: 34244265; PMCID: PMC8273462; DOI: 10.1136/bmjopen-2020-047017;

Jamieson L, Johnson LF, Matsimela K, Sande LA, d'Elbée M, Majam M, Johnson C, Chidarikire T, Hatzold K, Terris-Prestholt F, Nichols B, Meyer-Rath G. The cost effectiveness and optimal configuration of HIV self-test distribution in South Africa: a model analysis. BMJ Glob Health. 2021 07; 6(Suppl 4).View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 34275876; PMCID: PMC8287627; DOI: 10.1136/bmjgh-2021-005598;

Long LC, Rosen S, Nichols B, Larson BA, Ndlovu N, Meyer-Rath G. Getting resources to those who need them: the evidence we need to budget for underserved populations in sub-Saharan Africa. J Int AIDS Soc. 2021 07; 24 Suppl 3:e25707.View Related Profiles.

Nichols, Brooke
Larson, Bruce
Meyer-Rath, Gesine
Long, Lawrence
Rosen, Sydney

PMID: 34189873; PMCID: PMC8242975; DOI: 10.1002/jia2.25707;

Huber A, Pascoe S, Nichols B, Long L, Kuchukhidze S, Phiri B, Tchereni T, Rosen S. Differentiated Service Delivery Models for HIV Treatment in Malawi, South Africa, and Zambia: A Landscape Analysis. Glob Health Sci Pract. 2021 06 30; 9(2):296-307.View Related Profiles.

Nichols, Brooke
Long, Lawrence
Rosen, Sydney

PMID: 34234023; PMCID: PMC8324204; DOI: 10.9745/GHSP-D-20-00532;

Dovel K, Balakasi K, Gupta S, Mphande M, Robson I, Khan S, Amberbir A, Stilson C, van Oosterhout JJ, Doi N, Nichols BE. Frequency of visits to health facilities and HIV services offered to men, Malawi. Bull World Health Organ. 2021 Sep 01; 99(9):618-626. PMID: 34475599; PMCID: PMC8381098; DOI: 10.2471/BLT.20.278994;

Balakasi K, Nichols BE, Mphande M, Stillson C, Khan S, Kalande P, Robson I, Sanena M, Ng'ona K, van Oosterhout JJ, Doi N, Dovel K. Individual- and Facility-Level Factors Associated with Facility Testing among Men in Malawi: Findings from a Representative Community Survey. Diagnostics (Basel). 2021 May 26; 11(6). PMID: 34073217; PMCID: PMC8228120; DOI: 10.3390/diagnostics11060950;

Nichols BE, Jamieson L, Zhang SRC, Rao GA, Silal S, Pulliam JRC, Sanne I, Meyer-Rath G. The Role of Remdesivir in South Africa: Preventing COVID-19 Deaths Through Increasing Intensive Care Unit Capacity. Clin Infect Dis. 2021 05 04; 72(9):1642-1644.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine
Sanne, Ian

PMID: 32628744; PMCID: PMC7454458; DOI: 10.1093/cid/ciaa937;

Sy KTL, White LF, Nichols BE. Population density and basic reproductive number of COVID-19 across United States counties. PLoS One. 2021; 16(4):e0249271.View Related Profiles.

Nichols, Brooke
White, Laura

PMID: 33882054; PMCID: PMC8059825; DOI: 10.1371/journal.pone.0249271;

Nichols BE, Cele R, Lekodeba N, Tukei B, Ngorima-Mabhena N, Tiam A, Maotoe T, Sejana MV, Faturiyele IO, Chasela C, Rosen S, Fatti G. Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients. J Int AIDS Soc. 2021 04; 24(4):e25692.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 33838012; PMCID: PMC8035675; DOI: 10.1002/jia2.25692;

Girdwood S, Hannay E, Kassa H, Albert H, Carmona S, Nichols BE. Quantifying Rapid Antigen Diagnostic Resource Requirements for SARS-CoV-2: A Cost-Effectiveness Analysis of Testing Strategies for Five Countries in Sub-Saharan Africa. SSRN. 2021. View Publication

Rashid A, Sy KTL, Cabrejas JM, Nichols BE, Bhadelia N, Murray EJ. A clinician's primer on epidemiology for COVID-19. Med (N Y). 2021 Apr 09; 2(4):384-394.View Related Profiles.

Nichols, Brooke
Murray, Eleanor
Bhadelia, Nahid

PMID: 33681831; PMCID: PMC7914024; DOI: 10.1016/j.medj.2021.02.007;

Nichols BE, Cele R, Jamieson L, Long LC, Siwale Z, Banda P, Moyo C, Rosen S. Community-based delivery of HIV treatment in Zambia: costs and outcomes. AIDS. 2021 02 02; 35(2):299-306.View Related Profiles.

Nichols, Brooke
Long, Lawrence
Rosen, Sydney

PMID: 33170578; PMCID: PMC7810408; DOI: 10.1097/QAD.0000000000002737;

Jo Y, Jamieson L, Edoka I, Long L, Silal S, Pulliam JRC, Moultrie H, Sanne I, Meyer-Rath G, Nichols BE. Cost-effectiveness of Remdesivir and Dexamethasone for COVID-19 Treatment in South Africa. Open Forum Infect Dis. 2021 Mar; 8(3):ofab040.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine
Sanne, Ian
Long, Lawrence

PMID: 33732750; PMCID: PMC7928624; DOI: 10.1093/ofid/ofab040;

Nichols K, Girdwood SJ, Inglis A, Ondoa P, Sy KTL, Benade M, Tusiime AB, Kao K, Carmona S, Albert H, Nichols BE. Bringing Data Analytics to the Design of Optimized Diagnostic Networks in Low- and Middle-Income Countries: Process, Terms and Definitions. Diagnostics (Basel). 2020 Dec 24; 11(1). PMID: 33374315; PMCID: PMC7823670; DOI: 10.3390/diagnostics11010022;

Nsoesie EO, Sy KTL, Oladeji O, Sefala R, Nichols BE. Nowcasting and forecasting provincial-level SARS-CoV-2 case positivity using google search data in South Africa. medRxiv. 2020. View Publication

Girdwood SJ, Crompton T, Sharma M, Dorward J, Garrett N, Drain PK, Stevens W, Nichols BE. Cost-effectiveness of adoption strategies for point of care HIV viral load monitoring in South Africa. EClinicalMedicine. 2020 Nov; 28:100607. PMID: 33294817; PMCID: PMC7700965; DOI: 10.1016/j.eclinm.2020.100607;

Long L, Kuchukhidze S, Pascoe S, Nichols BE, Fox MP, Cele R, Govathson C, Huber AN, Flynn D, Rosen S. Retention in care and viral suppression in differentiated service delivery models for HIV treatment delivery in sub-Saharan Africa: a rapid systematic review. J Int AIDS Soc. 2020 11; 23(11):e25640.View Related Profiles.

Nichols, Brooke
Flynn, David
Long, Lawrence
Fox, Matthew
Rosen, Sydney

PMID: 33247517; PMCID: PMC7696000; DOI: 10.1002/jia2.25640;

Jo Y, Singh R, Rao G, Galea S, Nichols BE. Serological testing in addition to PCR screening for the re-opening of American colleges and universities: potential for cost-savings without compromising pandemic mitigation. medRxiv. 2020. View Publication

Jo Y, Jamieson L, Edoka I, Long L, Silal S, Pulliam JRC, Moultrie H, Sanne I, Meyer-Rath G, Nichols BE. Cost-effectiveness of remdesivir and dexamethasone for COVID-19 treatment in South Africa. medRxiv. 2020 Sep 27.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine
Sanne, Ian
Long, Lawrence

PMID: 32995824; PMCID: PMC7523165; DOI: 10.1101/2020.09.24.20200196;

Nichols BE, Offorjebe OA, Cele R, Shaba F, Balakasi K, Chivwara M, Hoffman RM, Long LC, Rosen S, Dovel K. Economic evaluation of facility-based HIV self-testing among adult outpatients in Malawi. J Int AIDS Soc. 2020 09; 23(9):e25612.View Related Profiles.

Nichols, Brooke
Long, Lawrence
Rosen, Sydney

PMID: 32909387; PMCID: PMC7507468; DOI: 10.1002/jia2.25612;

Technical Group of the COVID-19 Multi-Model Comparison Collaboration (the CMCC). Technical group report: model fitness-for-purpose assessment report. World Health Organization. Geneva. 2020. View Publication

van de Vijver DA, Nichols BE. Pre-treatment HIV drug resistance testing cost-effectiveness. EClinicalMedicine. 2020 May; 22:100381. PMID: 32478315; PMCID: PMC7251652; DOI: 10.1016/j.eclinm.2020.100381;

Silal S, Pulliam J, Meyer-Rath G, Nichols B, Jamieson L, Kimmie Z, Moultrie H. Estimating cases for COVID-19 in South Africa: Long-term national projections. 2020. View Publication

Masuku SD, Berhanu R, Van Rensburg C, Ndjeka N, Rosen S, Long L, Evans D, Nichols BE. Managing multidrug-resistant tuberculosis in South Africa: a budget impact analysis. Int J Tuberc Lung Dis. 2020 04 01; 24(4):376-382.View Related Profiles.

Nichols, Brooke
Long, Lawrence
Berhanu, Rebecca
Rosen, Sydney

PMID: 32317060; PMCID: PMC7656447; DOI: 10.5588/ijtld.19.0409;

Nichols BE, Kissler SM. Ending the HIV epidemic in the USA. Lancet HIV. 2020 07; 7(7):e454-e455. PMID: 32145761

Nichols BE, Girdwood SJ, Shibemba A, Sikota S, Gill CJ, Mwananyanda L, Noble L, Stewart-Isherwood L, Scott L, Carmona S, Rosen S, Stevens W. Cost and Impact of Dried Blood Spot Versus Plasma Separation Card for Scale-up of Viral Load Testing in Resource-limited Settings. Clin Infect Dis. 2020 03 03; 70(6):1014-1020.View Related Profiles.

Nichols, Brooke
Gill, Christopher
Mwananyanda, Lawrence
Rosen, Sydney

PMID: 31321438; PMCID: PMC7931834; DOI: 10.1093/cid/ciz338;

Dovel K, Shaba F, Offorjebe OA, Balakasi K, Nyirenda M, Phiri K, Gupta SK, Wong V, Tseng CH, Nichols BE, Cele R, Lungu E, Masina T, Coates TJ, Hoffman RM. Effect of facility-based HIV self-testing on uptake of testing among outpatients in Malawi: a cluster-randomised trial. Lancet Glob Health. 2020 02; 8(2):e276-e287. PMID: 31981557; DOI: 10.1016/S2214-109X(19)30534-0;

Hendrickson C, Long L, van de Vijver D, Boucher C, O'Bra H, Claassen CW, Njelesani M, Moyo C, Mumba DB, Subedar H, Mulenga L, Rosen S, Nichols BE. Novel metric for evaluating pre-exposure prophylaxis programme effectiveness in real-world settings. Lancet HIV. 2020 04; 7(4):e294-e300.View Related Profiles.

Nichols, Brooke
Long, Lawrence
Rosen, Sydney

PMID: 32014116; PMCID: PMC7263446; DOI: 10.1016/S2352-3018(19)30344-3;

Long L, Kuchukhidze S, Pascoe S, Nichols B, Cele R, Govathson C, Huber A, Flynn D, Rosen S. Differentiated models of service delivery for antiretroviral treatment of HIV in sub-Saharan Africa: a rapid review protocol. Syst Rev. 2019 12 06; 8(1):314.View Related Profiles.

Nichols, Brooke
Flynn, David
Long, Lawrence
Rosen, Sydney

PMID: 31810482; PMCID: PMC6896778; DOI: 10.1186/s13643-019-1210-6;

van Vliet MM, Hendrickson C, Nichols BE, Boucher CA, Peters RP, van de Vijver DA. Epidemiological impact and cost-effectiveness of providing long-acting pre-exposure prophylaxis to injectable contraceptive users for HIV prevention in South Africa: a modelling study. J Int AIDS Soc. 2019 12; 22(12):e25427. PMID: 31855323; PMCID: PMC6922023; DOI: 10.1002/jia2.25427;

Kuchukhidze S, Long LC, Pascoe S, Huber AN, Nichols BE, Fox MP, Rosen S . Differentiated models of service delivery (DSD) for antiretroviral treatment of HIV in sub-Saharan Africa: A review of the gray literature as of June 2019. AMBIT Project Report No. 03. Boston University and HE2RO. Boston, USA. 2019. View Publication

Popping S, Nichols B, Rijnders B, van Kampen J, Verbon A, Boucher C, van de Vijver D. Targeted HCV core antigen monitoring among HIV-positive men who have sex with men is cost-saving. J Virus Erad. 2019 Nov 04; 5(4):179-190. PMID: 31754441; PMCID: PMC6844408

Kuchukhidze S, Long L, Rosen S, Pascoe S, Huber A, Fox M, Nichols B. Provider costs associated with differentiated models of service delivery for HIV treatment in sub-Saharan Africa. AMBIT Project Report No. 2. Boston, USA. 2019. View Publication
Kuchukhidze S, Long L, Pascoe S, Huber A, Nichols B, Fox M, Rosen S. Patient benefits and costs associated with differentiated models of service delivery for HIV treatment in sub-Saharan Africa. AMBIT Project Report No. 1. Boston, USA. 2019. View Publication

Nichols BE, Girdwood SJ, Crompton T, Stewart-Isherwood L, Berrie L, Chimhamhiwa D, Moyo C, Kuehnle J, Stevens W, Rosen S. Monitoring viral load for the last mile: what will it cost? J Int AIDS Soc. 2019 09; 22(9):e25337.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 31515967; PMCID: PMC6742838; DOI: 10.1002/jia2.25337;

Girdwood SJ, Nichols BE, Moyo C, Crompton T, Chimhamhiwa D, Rosen S. Optimizing viral load testing access for the last mile: Geospatial cost model for point of care instrument placement. PLoS One. 2019; 14(8):e0221586.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 31449559; PMCID: PMC6709899; DOI: 10.1371/journal.pone.0221586;

Girdwood SJ, Nichols BE. Point-of-care assays for early infant diagnosis in Zimbabwe. Lancet HIV. 2019 03; 6(3):e146-e147. PMID: 30737188; DOI: 10.1016/S2352-3018(18)30335-7;

van de Vijver DAMC, Richter AK, Boucher CAB, Gunsenheimer-Bartmeyer B, Kollan C, Nichols BE, Spinner CD, Wasem J, Schewe K, Neumann A. Cost-effectiveness and budget effect of pre-exposure prophylaxis for HIV-1 prevention in Germany from 2018 to 2058. Euro Surveill. 2019 Feb; 24(7). PMID: 30782266; PMCID: PMC6381659; DOI: 10.2807/1560-7917.ES.2019.24.7.1800398;

Popping S, Hullegie SJ, Boerekamps A, Rijnders BJA, de Knegt RJ, Rockstroh JK, Verbon A, Boucher CAB, Nichols BE, van de Vijver DAMC. Early treatment of acute hepatitis C infection is cost-effective in HIV-infected men-who-have-sex-with-men. PLoS One. 2019; 14(1):e0210179. PMID: 30629662; PMCID: PMC6328146; DOI: 10.1371/journal.pone.0210179;

Nichols BE, Girdwood SJ, Crompton T, Stewart-Isherwood L, Berrie L, Chimhamhiwa D, Moyo C, Kuehnle J, Stevens W, Rosen S. Impact of a borderless sample transport network for scaling up viral load monitoring: results of a geospatial optimization model for Zambia. J Int AIDS Soc. 2018 12; 21(12):e25206.View Related Profiles.

Nichols, Brooke
Rosen, Sydney

PMID: 30515997; PMCID: PMC6280013; DOI: 10.1002/jia2.25206;

Dovel K, Shaba F, Nyirenda M, Offorjebe OA, Balakasi K, Phiri K, Nichols B, Tseng CH, Bardon A, Ngona K, Hoffman R. Evaluating the integration of HIV self-testing into low-resource health systems: study protocol for a cluster-randomized control trial from EQUIP Innovations. Trials. 2018 Sep 17; 19(1):498. PMID: 30223874; PMCID: PMC6142354; DOI: 10.1186/s13063-018-2878-y;

Smit M, van Zoest RA, Nichols BE, Vaartjes I, Smit C, van der Valk M, van Sighem A, Wit FW, Hallett TB, Reiss P. Cardiovascular Disease Prevention Policy in Human Immunodeficiency Virus: Recommendations From a Modeling Study. Clin Infect Dis. 2018 02 10; 66(5):743-750. PMID: 29029103; PMCID: PMC5850014; DOI: 10.1093/cid/cix858;

Phillips AN, Cambiano V, Nakagawa F, Revill P, Jordan MR, Hallett TB, Doherty M, De Luca A, Lundgren JD, Mhangara M, Apollo T, Mellors J, Nichols B, Parikh U, Pillay D, Rinke de Wit T, Sigaloff K, Havlir D, Kuritzkes DR, Pozniak A, van de Vijver D, Vitoria M, Wainberg MA, Raizes E, Bertagnolio S. Cost-effectiveness of public-health policy options in the presence of pretreatment NNRTI drug resistance in sub-Saharan Africa: a modelling study. Lancet HIV. 2018 03; 5(3):e146-e154. PMID: 29174084; PMCID: PMC5843989; DOI: 10.1016/S2352-3018(17)30190-X;

Luiken GPM, Joore IK, Taselaar A, Schuit SCE, Geerlings SE, Govers A, Rood PPM, Prins JM, Nichols BE, Verbon A, de Vries-Sluijs TEMS. Non-targeted HIV screening in emergency departments in the Netherlands. Neth J Med. 2017 Nov; 75(9):386-393. PMID: 29219811

Nichols BE, Meyer-Rath G. Cost-effectiveness of early identification of HIV infection. Lancet HIV. 2017 10; 4(10):e431-e432.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 28768605

Nichols BE, Boucher CAB, van de Vijver DAM. Methodological concerns regarding a PrEP model - Authors' reply. Lancet Infect Dis. 2017 05; 17(5):482-483. PMID: 28447955

Nichols BE, Boucher CAB, van der Valk M, Rijnders BJA, van de Vijver DAMC. Cost-effectiveness analysis of pre-exposure prophylaxis for HIV-1 prevention in the Netherlands: a mathematical modelling study. Lancet Infect Dis. 2016 Dec; 16(12):1423-1429. PMID: 27665989; DOI: 10.1016/S1473-3099(16)30311-5;

Phillips A, Shroufi A, Vojnov L, Cohn J, Roberts T, Ellman T, Bonner K, Rousseau C, Garnett G, Cambiano V, Nakagawa F, Ford D, Bansi-Matharu L, Miners A, Lundgren JD, Eaton JW, Parkes-Ratanshi R, Katz Z, Maman D, Ford N, Vitoria M, Doherty M, Dowdy D, Nichols B, Murtagh M, Wareham M, Palamountain KM, Chakanyuka Musanhu C, Stevens W, Katzenstein D, Ciaranello A, Barnabas R, Braithwaite RS, Bendavid E, Nathoo KJ, van de Vijver D, Wilson DP, Holmes C, Bershteyn A, Walker S, Raizes E, Jani I, Nelson LJ, Peeling R, Terris-Prestholt F, Murungu J, Mutasa-Apollo T, Hallett TB, Revill P. Sustainable HIV treatment in Africa through viral-load-informed differentiated care. Nature. 2015 Dec 03; 528(7580):S68-76. PMID: 26633768; PMCID: PMC4932825; DOI: 10.1038/nature16046;

Nichols BE, Götz HM, van Gorp EC, Verbon A, Rokx C, Boucher CA, van de Vijver DA. Partner Notification for Reduction of HIV-1 Transmission and Related Costs among Men Who Have Sex with Men: A Mathematical Modeling Study. PLoS One. 2015; 10(11):e0142576. PMID: 26554586; PMCID: PMC4640527; DOI: 10.1371/journal.pone.0142576;

Nichols BE, Sigaloff KC, Kityo C, Hamers RL, Baltussen R, Bertagnolio S, Jordan MR, Hallett TB, Boucher CA, de Wit TF, van de Vijver DA. Increasing the use of second-line therapy is a cost-effective approach to prevent the spread of drug-resistant HIV: a mathematical modelling study. J Int AIDS Soc. 2014; 17:19164. PMID: 25491351; PMCID: PMC4260459; DOI: 10.7448/IAS.17.1.19164;

Nichols BE, Baltussen R, van Dijk JH, Thuma PE, Nouwen JL, Boucher CA, van de Vijver DA. Cost-effectiveness of PrEP in HIV/AIDS control in Zambia: a stochastic league approach. J Acquir Immune Defic Syndr. 2014 Jun 01; 66(2):221-8. PMID: 24694930; DOI: 10.1097/QAI.0000000000000145;

Armstrong JC, Nichols BE, Wilson JM, Cosico RA, Shanks L. Spinal cord injury in the emergency context: review of program outcomes of a spinal cord injury rehabilitation program in Sri Lanka. Confl Health. 2014 Mar 20; 8(1):4. PMID: 24650231; PMCID: PMC3994551; DOI: 10.1186/1752-1505-8-4;

Nichols BE, Sigaloff KC, Kityo C, Mandaliya K, Hamers RL, Bertagnolio S, Jordan MR, Boucher CA, Rinke de Wit TF, van de Vijver DA. Averted HIV infections due to expanded antiretroviral treatment eligibility offsets risk of transmitted drug resistance: a modeling study. AIDS. 2014 Jan 02; 28(1):73-83. PMID: 23921620; DOI: 10.1097/01.aids.0000433239.01611.52;

Eaton JW, Menzies NA, Stover J, Cambiano V, Chindelevitch L, Cori A, Hontelez JA, Humair S, Kerr CC, Klein DJ, Mishra S, Mitchell KM, Nichols BE, Vickerman P, Bakker R, Bärnighausen T, Bershteyn A, Bloom DE, Boily MC, Chang ST, Cohen T, Dodd PJ, Fraser C, Gopalappa C, Lundgren J, Martin NK, Mikkelsen E, Mountain E, Pham QD, Pickles M, Phillips A, Platt L, Pretorius C, Prudden HJ, Salomon JA, van de Vijver DA, de Vlas SJ, Wagner BG, White RG, Wilson DP, Zhang L, Blandford J, Meyer-Rath G, Remme M, Revill P, Sangrujee N, Terris-Prestholt F, Doherty M, Shaffer N, Easterbrook PJ, Hirnschall G, Hallett TB. Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models. Lancet Glob Health. 2013 Dec 10; 2(1):23-34.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 25083415; PMCID: PMC4114402; DOI: 10.1016/S2214-109X(13)70172-4;

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 25104632; DOI: 10.1016/S2214-109X(13)70172-4;

van de Vijver DA, Nichols BE, Abbas UL, Boucher CA, Cambiano V, Eaton JW, Glaubius R, Lythgoe K, Mellors J, Phillips A, Sigaloff KC, Hallett TB. Preexposure prophylaxis will have a limited impact on HIV-1 drug resistance in sub-Saharan Africa: a comparison of mathematical models. AIDS. 2013 Nov 28; 27(18):2943-51. PMID: 23939237; DOI: 10.1097/01.aids.0000433237.63560.20;

Nichols BE, Boucher CA, van Dijk JH, Thuma PE, Nouwen JL, Baltussen R, van de Wijgert J, Sloot PM, van de Vijver DA. Cost-effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV-1 infections in rural Zambia: a modeling study. PLoS One. 2013; 8(3):e59549. PMID: 23527217; PMCID: PMC3601101; DOI: 10.1371/journal.pone.0059549;

HIV treatment as prevention: models, data, and questions--towards evidence-based decision-making. PLoS Med. 2012; 9(7):e1001259.View Related Profiles.

Nichols, Brooke
Meyer-Rath, Gesine

PMID: 22802739; PMCID: PMC3393655; DOI: 10.1371/journal.pmed.1001259;

Nichols BE, Nkalamo D, Whitcomb BW. Density of drinking establishments and HIV prevalence in a migrant town in Namibia. AIDS Behav. 2012 May; 16(4):829-34. PMID: 21538085; DOI: 10.1007/s10461-011-9956-4;

Nichols BE, Boucher CA, van de Vijver DA. HIV testing and antiretroviral treatment strategies for prevention of HIV infection: impact on antiretroviral drug resistance. J Intern Med. 2011 Dec; 270(6):532-49. PMID: 21929723; DOI: 10.1111/j.1365-2796.2011.02456.x;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 139 publications over 15 distinct years, with a maximum of 21 publications in 2021 and 2023

Bar chart showing 139 publications over 15 distinct years, with a maximum of 21 publications in 2021 and 2023

Year	Publications
2011	1
2012	2
2013	4
2014	4
2015	2
2016	1
2017	4
2018	3
2019	11
2020	15
2021	21
2022	15
2023	21
2024	17
2025	18

Media Mentions
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Recent (within 3 months)

Child Deaths Set To Rise For First Time This Century, Report

Newsweek 12/4/2025

The Shutdown of U.S.A.I.D. Has Already Killed Hundreds of Thousands

The New Yorker 11/5/2025

Older

USAID cuts have caused more than 330,000 deaths worldwide, BU professor estimates

Boston Globe 7/1/2025

Marco Rubio said no one has died due to U.S. aid cuts. This mom disagrees

NPR 5/28/2025

Trump’s Legacy Will Be the Countless People Killed by His Policies

The Nation 5/1/2025

Is America going to let Trump get away with this? | Opinion

Detroit Free Press 4/29/2025

Loaded for Bear: 100-plus deaths an hour — the toll of Trump’s gutting of Pepfar and USAid

Daily Maverick 4/29/2025

From dread to action: Tracking the Trump-Musk death toll from cuts to USAID

Salon 4/26/2025

Is Covid ‘Under Control’ in the US? Experts Say Yes

Kaiser Health News 9/26/2022

A guide to help you keep up with the Omicron subvariants

The Salt Lake Tribune 5/9/2022

A guide to help you keep track of all the Omicron subvariants

Los Angeles Times 5/6/2022

Trying to keep up with the omicron subvariants? Here’s a guide

PolitiFact 5/2/2022

How to have a COVID-safe Thanksgiving gathering

National Geographic 11/18/2021

The coronavirus variants: What you need to know

PolitiFact 7/7/2021

This chart shows how younger people are lagging in getting COVID vaccinations in Mass.

The Boston Globe 6/2/2021

Why did the federal guidance about wearing face masks change?

Poynter 5/26/2021

About face on mask-wearing: Why did the federal guidance change?

PoltiFact 5/25/2021

‘Youth is not invincible’: 9 experts dispute Joe Rogan’s vaccine advice for healthy 21-year-olds

PolitiFact 4/28/2021

Tucker Carlson falsely claims COVID-19 vaccines might not work

PolitiFact 4/15/2021

You’re fully vaccinated against COVID-19. What can you do now?

PolitiFact 3/11/2021

Vaccines are up and infections are down under Biden, but it’s not all his doing

PolitiFact 2/23/2021

“COVID-19 infections down 61% from Trump’s last day. COVID-19 vaccinations up 85% from Trump’s last day. Competence Matters.”

Politifact 2/23/2021

Many States Don't Know Who's Getting COVID-19 Vaccines. That's a Huge Problem for Equity

TIME 1/28/2021

Where the coronavirus pandemic stands, holiday edition

PolitiFact 12/21/2020

Many Americans say they don’t want a vaccine. Should we be worried?

PolitiFact 12/8/2020

Former Pfizer employee wrong that coronavirus pandemic is ‘effectively over’ in UK

PolitiFact 12/2/2020

Is Florida doing better on COVID-19 than “locked down” states?

PolitiFact 12/2/2020

Closing Schools Alone Is Not Going to Stop the Coronavirus

The New York Times 11/19/2020

Doctors may be better equipped to handle latest virus surge

Associated Press 11/11/2020

US hits record COVID-19 hospitalizations amid virus surge

Associated Press 11/11/2020

Three ways the US CDC can regain the public’s trust

Quartz 11/9/2020

Donald Trump stated on October 22, 2020 in a presidential debate: “We are rounding the turn (on coronavirus). We are rounding the corner.”

PolitiFact 10/23/2020

A C.D.C. scientist acknowledged dated guidance on schools and childhood transmission.

The New York Times 10/23/2020

Schoolchildren Seem Unlikely to Fuel Coronavirus Surges, Scientists Say

The New York Times 10/22/2020

Covid-19 Live Updates: Boston Public Schools Stop In-Person Learning

The New York Times 10/21/2020

Donald Trump stated on October 12, 2020 in a tweet.: “The World Health Organization just admitted that I was right. Lockdowns are killing countries all over the world. The cure cannot be worse than the problem itself.”

PoltiFact 10/15/2020

BU Expert Urges Putting the Brakes on Massachusetts Relaxed COVID-19 Rules

BU Today 10/9/2020

Not so fast on indoor gatherings

The Boston Globe 10/4/2020

A QR code could decide whether you go back to work

Quartz 9/30/2020

National survey finds low school COVID-19 rates after first week back

Boston 25 News 9/23/2020

Population Density Does Not Doom Cities to Pandemic Dangers

Scientific American 9/16/2020

“Florida is doing over five times better” than New Jersey and New York in COVID-19 deaths per million

PolitiFact 7/31/2020

COVID-19 cases are “up only because of our big number testing.”

Politifact 6/24/2020

Is a second wave of coronavirus coming?

PolitiFact 6/22/2020

A number of Southern and Western states are seeing a spike in COVID-19 cases. Why aren’t their death rates rising, too?

The Boston Globe 6/22/2020

“Cases, numbers and deaths (of COVID-19) are going down all over the Country!”

PolitiFact 5/28/2020

2022 Boston University School of Public Health: Excellence in Research Early Career Award

Contact for Mentoring:

617.638.5234

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