Arjun Guha, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

PhD, Manipal University
BS, Wabash College

Research Interests: Cell fate specification and cellular plasticity in lung development and repair, Non-classical stem cell hierarchies, Pulmonary neuroepithelial cells and their microenvironment, and Notch signaling

Boston University
Evans Center for Interdisciplinary Biomedical Research

Regulation of Upk3a-Clara Cells during homeostatsis and post-injury repair
09/05/2014 - 08/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Sain Basu D, Bhavsar R, Gulami I, Chavda S, Lingamallu SM, Muddashetty R, Veeranna C, Chattarji S, Thimmulappa R, Bhattacharya A, Guha A. FMRP protects the lung from xenobiotic stress by facilitating the integrated stress response. J Cell Sci. 2022 05 01; 135(9). PMID: 35319067
  2. Kizhedathu A, Chhajed P, Yeramala L, Sain Basu D, Mukherjee T, Vinothkumar KR, Guha A. Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts. Elife. 2021 10 08; 10. PMID: 34622778; PMCID: PMC8594940; DOI: 10.7554/eLife.68636;
  3. Kizhedathu A, Kunnappallil RS, Bagul AV, Verma P, Guha A. Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts. Elife. 2020 09 02; 9. PMID: 32876044; PMCID: PMC7505655; DOI: 10.7554/eLife.57056;
  4. Kizhedathu A, Bagul AV, Guha A. Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast growth and tracheal hypertrophy in Drosophila. Elife. 2018 04 16; 7. PMID: 29658881; PMCID: PMC5953539; DOI: 10.7554/eLife.29988;
  5. Guha A, Deshpande A, Jain A, Sebastiani P, Cardoso WV. Uroplakin 3a+ Cells Are a Distinctive Population of Epithelial Progenitors that Contribute to Airway Maintenance and Post-injury Repair. Cell Rep. 2017 Apr 11; 19(2):246-254.View Related Profiles. PMID: 28402849; DOI: 10.1016/j.celrep.2017.03.051;
  6. Rao PR, Lin L, Huang H, Guha A, Roy S, Kornberg TB. Developmental compartments in the larval trachea of Drosophila. Elife. 2015 Oct 22; 4. PMID: 26491942; PMCID: PMC4718809; DOI: 10.7554/eLife.08666;
  7. Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S. Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16; 15:72. PMID: 26178733; PMCID: PMC4504078; DOI: 10.1186/s12890-015-0065-4;
  8. Guha A, Vasconcelos M, Zhao R, Gower AC, Rajagopal J, Cardoso WV. Analysis of Notch signaling-dependent gene expression in developing airways reveals diversity of Clara cells. PLoS One. 2014; 9(2):e88848.View Related Profiles. PMID: 24586412; PMCID: PMC3931645; DOI: 10.1371/journal.pone.0088848;
  9. Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV. Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12592-7.View Related Profiles. PMID: 22797898; PMCID: PMC3412014; DOI: 10.1073/pnas.1204710109;
  10. Guha A, Lin L, Kornberg TB. Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis. Dev Biol. 2009 Nov 15; 335(2):317-26. PMID: 19751719; PMCID: PMC2784283; DOI: 10.1016/j.ydbio.2009.09.005;
Showing 10 of 13 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 13 publications over 12 distinct years, with a maximum of 2 publications in 2015


Contact for Mentoring:

72 E. Concord St Housman (R)
Boston MA 02118
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