Anthony Griffiths | Profiles RNS

Anthony Griffiths, PhD

Professor

Boston University Chobanian & Avedisian School of Medicine

Virology, Immunology & Microbiology

PhD, University of Cambridge
BSc, University of Reading

Websites

	Microbiology Faculty
	National Emerging Infectious Diseases Laboratories Faculty
	UT Health San Antonio - Graduate School of Biomedical Sciences
	LinkedIn
	ResearchGate
	Griffiths Lab website

ORCID : 000-0001-5435-8364

The family Filoviridae includes Ebola virus and Marburg virus, which are associated with sporadic outbreaks and high case fatality rates. A maximum containment laboratory (Biosafety Level-4) is required to study the infectious forms of these viruses. Dr. Griffiths’ laboratory is interested in multiple aspects of filovirus biology with a view to exploiting this knowledge to further the development of vaccines and therapeutics.

Faculty
Boston University
National Emerging Infectious Disease Lab

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research

Efficacy testing of a Marburg Virus Monoclonal Antibody Medical Countermeasure
01/16/2023 - 08/31/2028 (Subcontract PI)
Mapp Biopharmaceutical, Inc. HHS ASPR BARDA

Vaccines for Prevention of RG3 and RG4 Emerging Tickborne Viral Diseases
08/20/2021 - 07/31/2026 (Subcontract PI)
University of Connecticut NIH NIAID
1R01AI152241-01

National Emerging Infectious Diseases Laboratories Operations
07/08/2021 - 06/30/2026 (Key Person)
PI: Nancy J. Sullivan, ScD
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-09

Cellular Nanosponges as a Medical Countermeasure to Emerging Virus Threats
05/13/2021 - 05/12/2026 (Subcontract PI)
University of California, San Diego DOD Threat Reduction

Immunogenicity and Efficacy Testing of Medical Countermeasures (Vaccines and Other Biologics) Against BSL-4 Pathogens in NHPs
06/23/2020 - 11/28/2025 (Subcontract PI)
Battelle Memorial Institute NIH NIAID

Exploratory Single-Dose Intramuscular Immunogenicity, Protection from SARS-CoV-2 and Evaluation of VAERD Study in Golden Syrian Hamsters
10/05/2020 - 10/04/2025 (Subcontract PI)
Merck, Sharp & Dohme LLC HHS ASPR BARDA
HHSO10020160031C

Uncovering the RNA regulatory Mechanisms driving pathogenicity at mass-caualty viruses: Merging the technologies of RNA biology and enhanced biosafety to create the next generation of broad spectrum,
10/01/2022 - 09/30/2025 (Multi-PI)
PI: Anthony Griffiths, PhD
Howard Hughes Medical Institute

Efficacy of Wyss-vaccine platforms in hamster model of SARS-CoV-2 infection
12/01/2020 - 01/31/2025 (PI)
Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard

Assays in Support of Filovirus Nonhuman Primate Studies for Advancement of Medical Countermeasures
04/14/2022 - 12/31/2024 (Subcontract PI)
Battelle Memorial Institute HHS ASPR BARDA

Serologic and Molecular Studies of human anti-hCoV antibody cross-immunity and protective responses among endemic HCoVs and SARS-CoV2
09/17/2021 - 08/31/2024 (Subcontract PI)
Dana-Farber Cancer Institute NIH NIAID
5R01Al161152-02

Showing 10 of 55 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Shrock EL, Timms RT, Kula T, Mena EL, West AP, Guo R, Lee IH, Cohen AA, McKay LGA, Bi C, Leng Y, Fujimura E, Horns F, Li M, Wesemann DR, Griffiths A, Gewurz BE, Bjorkman PJ, Elledge SJ. Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses. Science. 2023 Apr 07; 380(6640):eadc9498.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 37023193

Carter B, Huang P, Liu G, Liang Y, Lin PJC, Peng BH, McKay LGA, Dimitrakakis A, Hsu J, Tat V, Saenkham-Huntsinger P, Chen J, Kaseke C, Gaiha GD, Xu Q, Griffiths A, Tam YK, Tseng CK, Gifford DK. A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta. Front Immunol. 2023; 14:1135815.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 36969239; PMCID: PMC10033589; DOI: 10.3389/fimmu.2023.1135815;

Griffiths, Anthony
McKay, Lindsay

PMID: 36969239; PMCID: PMC10033589; DOI: 10.3389/fimmu.2023.1135815;

Kuhn JH, Adkins S, Alkhovsky SV, Avšic-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bandte M, Beer M, Bejerman N, Bergeron É, Biedenkopf N, Bigarré L, Blair CD, Blasdell KR, Bradfute SB, Briese T, Brown PA, Bruggmann R, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Candresse T, Carson J, Casas I, Chandran K, Charrel RN, Chiaki Y, Crane A, Crane M, Dacheux L, Bó ED, de la Torre JC, de Lamballerie X, de Souza WM, de Swart RL, Dheilly NM, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Drexler JF, Duprex WP, Dürrwald R, Easton AJ, Elbeaino T, Ergünay K, Feng G, Feuvrier C, Firth AE, Fooks AR, Formenty PBH, Freitas-Astúa J, Gago-Zachert S, García ML, García-Sastre A, Garrison AR, Godwin SE, Gonzalez JJ, de Bellocq JG, Griffiths A, Groschup MH, Günther S, Hammond J, Hepojoki J, Hierweger MM, Hongo S, Horie M, Horikawa H, Hughes HR, Hume AJ, Hyndman TH, Jiang D, Jonson GB, Junglen S, Kadono F, Karlin DG, Klempa B, Klingström J, Koch MC, Kondo H, Koonin EV, Krásová J, Krupovic M, Kubota K, Kuzmin IV, Laenen L, Lambert AJ, Li J, Li JM, Lieffrig F, Lukashevich IS, Luo D, Maes P, Marklewitz M, Marshall SH, Marzano SL, McCauley JW, Mirazimi A, Mohr PG, Moody NJG, Morita Y, Morrison RN, Mühlberger E, Naidu R, Natsuaki T, Navarro JA, Neriya Y, Netesov SV, Neumann G, Nowotny N, Ochoa-Corona FM, Palacios G, Pallandre L, Pallás V, Papa A, Paraskevopoulou S, Parrish CR, Pauvolid-Corrêa A, Paweska JT, Pérez DR, Pfaff F, Plemper RK, Postler TS, Pozet F, Radoshitzky SR, Ramos-González PL, Rehanek M, Resende RO, Reyes CA, Romanowski V, Rubbenstroth D, Rubino L, Rumbou A, Runstadler JA, Rupp M, Sabanadzovic S, Sasaya T, Schmidt-Posthaus H, Schwemmle M, Seuberlich T, Sharpe SR, Shi M, Sironi M, Smither S, Song JW, Spann KM, Spengler JR, Stenglein MD, Takada A, Tesh RB, Tešíková J, Thornburg NJ, Tischler ND, Tomitaka Y, Tomonaga K, Tordo N, Tsunekawa K, Turina M, Tzanetakis IE, Vaira AM, van den Hoogen B, Vanmechelen B, Vasilakis N, Verbeek M, von Bargen S, Wada J, Wahl V, Walker PJ, Whitfield AE, Williams JV, Wolf YI, Yamasaki J, Yanagisawa H, Ye G, Zhang YZ, Økland AL. 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2022 Dec; 167(12):2857-2906.View Related Profiles.

Hume, Adam
Griffiths, Anthony
Muhlberger, Elke

PMID: 36437428; PMCID: PMC9847503; DOI: 10.1007/s00705-022-05546-z;

Alfson KJ, Goez-Gazi Y, Gazi M, Chou YL, Niemuth NA, Mattix ME, Staples H, Klaffke B, Rodriguez GF, Escareno P, Bartley C, Ticer A, Clemmons EA, Dutton Iii JW, Griffiths A, Meister GT, Sanford DC, Cirimotich CM, Carrion R. Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development. Vaccines (Basel). 2022 Oct 15; 10(10). PMID: 36298588; PMCID: PMC9611481; DOI: 10.3390/vaccines10101723;

Cross RW, Longini IM, Becker S, Bok K, Boucher D, Carroll MW, Díaz JV, Dowling WE, Draghia-Akli R, Duworko JT, Dye JM, Egan MA, Fast P, Finan A, Finch C, Fleming TR, Fusco J, Geisbert TW, Griffiths A, Günther S, Hensley LE, Honko A, Hunegnaw R, Jakubik J, Ledgerwood J, Luhn K, Matassov D, Meshulam J, Nelson EV, Parks CL, Rustomjee R, Safronetz D, Schwartz LM, Smith D, Smock P, Sow Y, Spiropoulou CF, Sullivan NJ, Warfield KL, Wolfe D, Woolsey C, Zahn R, Henao-Restrepo AM, Muñoz-Fontela C, Marzi A. An introduction to the Marburg virus vaccine consortium, MARVAC. PLoS Pathog. 2022 Oct; 18(10):e1010805.View Related Profiles.

Griffiths, Anthony
Nelson, Emily
Sullivan, Nancy

PMID: 36227853; PMCID: PMC9560149; DOI: 10.1371/journal.ppat.1010805;

Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schäfer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA. IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern. Nat Commun. 2022 Oct 03; 13(1):5814.View Related Profiles.

Griffiths, Anthony
Storm, Nadia

PMID: 36192374; PMCID: PMC9528872; DOI: 10.1038/s41467-022-33030-4;

Schwake C, McKay L, Griffiths A, Scartelli C, Flaumenhaft R, Chishti AH. BDA-410 inhibits SARS-CoV-2 main protease activity and viral replication in mammalian cells. J Cell Mol Med. 2022 Oct; 26(19):5095-5098.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 36082511; PMCID: PMC9537889; DOI: 10.1111/jcmm.17442;

Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK. IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2. Sci Immunol. 2022 Sep 09; 7(75):eabl9943.View Related Profiles.

Honko, Anna
Griffiths, Anthony
McKay, Lindsay
Storm, Nadia

PMID: 35771946; PMCID: PMC9273042; DOI: 10.1126/sciimmunol.abl9943;

Alfson KJ, Goez-Gazi Y, Gazi M, Chou YL, Niemuth NA, Mattix ME, Staples HM, Klaffke B, Rodriguez GF, Bartley C, Ticer A, Clemmons EA, Dutton JW, Griffiths A, Meister GT, Sanford DC, Cirimotich CM, Carrion R. Development of a Well-Characterized Cynomolgus Macaque Model of Marburg Virus Disease for Support of Vaccine and Therapy Development. Vaccines (Basel). 2022 Aug 14; 10(8). PMID: 36016203; PMCID: PMC9414819; DOI: 10.3390/vaccines10081314;

Showing 10 of 77 results. Show More

Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC. Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol. 2022 Aug 12; 7(74):eabo3425.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 35536154; PMCID: PMC9097876; DOI: 10.1126/sciimmunol.abo3425;

Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz ÖH, Kwon DS. Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival. Clin Infect Dis. 2022 03 23; 74(6):1081-1084.View Related Profiles.

Honko, Anna
Griffiths, Anthony

PMID: 34245255; PMCID: PMC8406863; DOI: 10.1093/cid/ciab623;

Ciencewicki JM, Herbert AS, Storm N, Josleyn NM, Huie KE, McKay LGA, Griffiths A, Dye JM, Willis T, Arora V. Characterization of an Anti-Ebola Virus Hyperimmune Globulin Derived From Convalescent Plasma. J Infect Dis. 2022 02 15; 225(4):733-740.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay
Storm, Nadia

PMID: 34448858

Nabel KG, Clark SA, Shankar S, Pan J, Clark LE, Yang P, Coscia A, McKay LGA, Varnum HH, Brusic V, Tolan NV, Zhou G, Desjardins M, Turbett SE, Kanjilal S, Sherman AC, Dighe A, LaRocque RC, Ryan ET, Tylek C, Cohen-Solal JF, Darcy AT, Tavella D, Clabbers A, Fan Y, Griffiths A, Correia IR, Seagal J, Baden LR, Charles RC, Abraham J. Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science. 2022 01 21; 375(6578):eabl6251.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 34855508; PMCID: PMC9127715; DOI: 10.1126/science.abl6251;

Kuhn JH, Adkins S, Agwanda BR, Al Kubrusli R, Alkhovsky SV, Amarasinghe GK, Avšic-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Basler CF, Bavari S, Beer M, Bejerman N, Bennett AJ, Bente DA, Bergeron É, Bird BH, Blair CD, Blasdell KR, Blystad DR, Bojko J, Borth WB, Bradfute S, Breyta R, Briese T, Brown PA, Brown JK, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Cao M, Casas I, Chandran K, Charrel RN, Cheng Q, Chiaki Y, Chiapello M, Choi IR, Ciuffo M, Clegg JCS, Crozier I, Dal Bó E, de la Torre JC, de Lamballerie X, de Swart RL, Debat H, Dheilly NM, Di Cicco E, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolnik O, Drebot MA, Drexler JF, Dundon WG, Duprex WP, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K, Ferguson HW, Fooks AR, Forgia M, Formenty PBH, Fránová J, Freitas-Astúa J, Fu J, Fürl S, Gago-Zachert S, Gao GF, García ML, García-Sastre A, Garrison AR, Gaskin T, Gonzalez JJ, Griffiths A, Goldberg TL, Groschup MH, Günther S, Hall RA, Hammond J, Han T, Hepojoki J, Hewson R, Hong J, Hong N, Hongo S, Horie M, Hu JS, Hu T, Hughes HR, Hüttner F, Hyndman TH, Ilyas M, Jalkanen R, Jiang D, Jonson GB, Junglen S, Kadono F, Kaukinen KH, Kawate M, Klempa B, Klingström J, Kobinger G, Koloniuk I, Kondo H, Koonin EV, Krupovic M, Kubota K, Kurath G, Laenen L, Lambert AJ, Langevin SL, Lee B, Lefkowitz EJ, Leroy EM, Li S, Li L, Li J, Liu H, Lukashevich IS, Maes P, de Souza WM, Marklewitz M, Marshall SH, Marzano SL, Massart S, McCauley JW, Melzer M, Mielke-Ehret N, Miller KM, Ming TJ, Mirazimi A, Mordecai GJ, Mühlbach HP, Mühlberger E, Naidu R, Natsuaki T, Navarro JA, Netesov SV, Neumann G, Nowotny N, Nunes MRT, Olmedo-Velarde A, Palacios G, Pallás V, Pályi B, Papa A, Paraskevopoulou S, Park AC, Parrish CR, Patterson DA, Pauvolid-Corrêa A, Paweska JT, Payne S, Peracchio C, Pérez DR, Postler TS, Qi L, Radoshitzky SR, Resende RO, Reyes CA, Rima BK, Luna GR, Romanowski V, Rota P, Rubbenstroth D, Rubino L, Runstadler JA, Sabanadzovic S, Sall AA, Salvato MS, Sang R, Sasaya T, Schulze AD, Schwemmle M, Shi M, Shí X, Shí Z, Shimomoto Y, Shirako Y, Siddell SG, Simmonds P, Sironi M, Smagghe G, Smither S, Song JW, Spann K, Spengler JR, Stenglein MD, Stone DM, Sugano J, Suttle CA, Tabata A, Takada A, Takeuchi S, Tchouassi DP, Teffer A, Tesh RB, Thornburg NJ, Tomitaka Y, Tomonaga K, Tordo N, Torto B, Towner JS, Tsuda S, Tu C, Turina M, Tzanetakis IE, Uchida J, Usugi T, Vaira AM, Vallino M, van den Hoogen B, Varsani A, Vasilakis N, Verbeek M, von Bargen S, Wada J, Wahl V, Walker PJ, Wang LF, Wang G, Wang Y, Wang Y, Waqas M, Wèi T, Wen S, Whitfield AE, Williams JV, Wolf YI, Wu J, Xu L, Yanagisawa H, Yang C, Yang Z, Zerbini FM, Zhai L, Zhang YZ, Zhang S, Zhang J, Zhang Z, Zhou X. Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2021 Dec; 166(12):3567-3579.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke

PMID: 34786611

Kuhn JH, Adkins S, Agwanda BR, Al Kubrusli R, Alkhovsky SV, Amarasinghe GK, Avšic-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Basler CF, Bavari S, Beer M, Bejerman N, Bennett AJ, Bente DA, Bergeron É, Bird BH, Blair CD, Blasdell KR, Blystad DR, Bojko J, Borth WB, Bradfute S, Breyta R, Briese T, Brown PA, Brown JK, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Cao M, Casas I, Chandran K, Charrel RN, Cheng Q, Chiaki Y, Chiapello M, Choi IR, Ciuffo M, Clegg JCS, Crozier I, Dal Bó E, de la Torre JC, de Lamballerie X, de Swart RL, Debat H, Dheilly NM, Di Cicco E, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolnik O, Drebot MA, Drexler JF, Dundon WG, Duprex WP, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K, Ferguson HW, Fooks AR, Forgia M, Formenty PBH, Fránová J, Freitas-Astúa J, Fu J, Fürl S, Gago-Zachert S, Gao GF, García ML, García-Sastre A, Garrison AR, Gaskin T, Gonzalez JJ, Griffiths A, Goldberg TL, Groschup MH, Günther S, Hall RA, Hammond J, Han T, Hepojoki J, Hewson R, Hong J, Hong N, Hongo S, Horie M, Hu JS, Hu T, Hughes HR, Hüttner F, Hyndman TH, Ilyas M, Jalkanen R, Jiang D, Jonson GB, Junglen S, Kadono F, Kaukinen KH, Kawate M, Klempa B, Klingström J, Kobinger G, Koloniuk I, Kondo H, Koonin EV, Krupovic M, Kubota K, Kurath G, Laenen L, Lambert AJ, Langevin SL, Lee B, Lefkowitz EJ, Leroy EM, Li S, Li L, Li J, Liu H, Lukashevich IS, Maes P, de Souza WM, Marklewitz M, Marshall SH, Marzano SL, Massart S, McCauley JW, Melzer M, Mielke-Ehret N, Miller KM, Ming TJ, Mirazimi A, Mordecai GJ, Mühlbach HP, Mühlberger E, Naidu R, Natsuaki T, Navarro JA, Netesov SV, Neumann G, Nowotny N, Nunes MRT, Olmedo-Velarde A, Palacios G, Pallás V, Pályi B, Papa A, Paraskevopoulou S, Park AC, Parrish CR, Patterson DA, Pauvolid-Corrêa A, Paweska JT, Payne S, Peracchio C, Pérez DR, Postler TS, Qi L, Radoshitzky SR, Resende RO, Reyes CA, Rima BK, Luna GR, Romanowski V, Rota P, Rubbenstroth D, Rubino L, Runstadler JA, Sabanadzovic S, Sall AA, Salvato MS, Sang R, Sasaya T, Schulze AD, Schwemmle M, Shi M, Shí X, Shí Z, Shimomoto Y, Shirako Y, Siddell SG, Simmonds P, Sironi M, Smagghe G, Smither S, Song JW, Spann K, Spengler JR, Stenglein MD, Stone DM, Sugano J, Suttle CA, Tabata A, Takada A, Takeuchi S, Tchouassi DP, Teffer A, Tesh RB, Thornburg NJ, Tomitaka Y, Tomonaga K, Tordo N, Torto B, Towner JS, Tsuda S, Tu C, Turina M, Tzanetakis IE, Uchida J, Usugi T, Vaira AM, Vallino M, van den Hoogen B, Varsani A, Vasilakis N, Verbeek M, von Bargen S, Wada J, Wahl V, Walker PJ, Wang LF, Wang G, Wang Y, Wang Y, Waqas M, Wèi T, Wen S, Whitfield AE, Williams JV, Wolf YI, Wu J, Xu L, Yanagisawa H, Yang C, Yang Z, Zerbini FM, Zhai L, Zhang YZ, Zhang S, Zhang J, Zhang Z, Zhou X. 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2021 Dec; 166(12):3513-3566.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke

PMID: 34463877; PMCID: PMC8627462; DOI: 10.1007/s00705-021-05143-6;

Ai X, Wang D, Honko A, Duan Y, Gavrish I, Fang RH, Griffiths A, Gao W, Zhang L. Surface Glycan Modification of Cellular Nanosponges to Promote SARS-CoV-2 Inhibition. J Am Chem Soc. 2021 10 27; 143(42):17615-17621.View Related Profiles.

Honko, Anna
Griffiths, Anthony

PMID: 34647745; PMCID: PMC8525344; DOI: 10.1021/jacs.1c07798;

Langellotto F, Dellacherie MO, Yeager C, Ijaz H, Yu J, Cheng CA, Dimitrakakis N, Seiler BT, Gebre MS, Gilboa T, Johnson R, Storm N, Bardales S, Graveline A, White D, Tringides CM, Cartwright MJ, Doherty EJ, Honko A, Griffiths A, Barouch DH, Walt DR, Mooney DJ. A Modular Biomaterial Scaffold-Based Vaccine Elicits Durable Adaptive Immunity to Subunit SARS-CoV-2 Antigens. Adv Healthc Mater. 2021 11; 10(22):e2101370.View Related Profiles.

Honko, Anna
Griffiths, Anthony
Storm, Nadia

PMID: 34605223; PMCID: PMC8652677; DOI: 10.1002/adhm.202101370;

Johnson RI, Boczkowska B, Alfson K, Weary T, Menzie H, Delgado J, Rodriguez G, Carrion R, Griffiths A. Identification and Characterization of Defective Viral Genomes in Ebola Virus-Infected Rhesus Macaques. J Virol. 2021 08 10; 95(17):e0071421. PMID: 34160256; PMCID: PMC8354239; DOI: 10.1128/JVI.00714-21;

Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Naninck T, Kahlaoui N, Lemaitre J, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Contreras V, Marlin R, Tsong Fang RH, Chapon C, van der Werf S, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Le Grand R, Vandenberghe LH. An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates. Cell Host Microbe. 2021 09 08; 29(9):1437-1453.e8.View Related Profiles.

Honko, Anna
Griffiths, Anthony
Storm, Nadia

PMID: 34428428; PMCID: PMC8346325; DOI: 10.1016/j.chom.2021.08.002;

Colombani T, Eggermont LJ, Rogers ZJ, McKay LGA, Avena LE, Johnson RI, Storm N, Griffiths A, Bencherif SA. Biomaterials and Oxygen Join Forces to Shape the Immune Response and Boost COVID-19 Vaccines. Adv Sci (Weinh). 2021 09; 8(18):2100316.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay
Storm, Nadia

PMID: 34580619; PMCID: PMC8209904; DOI: 10.1002/advs.202100316;

Niemuth NA, Fallacara D, Triplett CA, Tamrakar SM, Rajbhandari A, Florence C, Ward L, Griffiths A, Carrion R, Goez-Gazi Y, Alfson KJ, Staples HM, Brasel T, Comer JE, Massey S, Smith J, Kocsis A, Lowry J, Johnston SC, Nalca A, Goff AJ, Shurtleff AC, Pitt ML, Trefry J, Fay MP. Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease. PLoS One. 2021; 16(7):e0252874. PMID: 34214118; PMCID: PMC8253449; DOI: 10.1371/journal.pone.0252874;

Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Brusic V, Choudhary MC, Regan J, Li JZ, Griffiths A, Abraham J. SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms. Cell. 2021 05 13; 184(10):2605-2617.e18.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 33831372; PMCID: PMC7962548; DOI: 10.1016/j.cell.2021.03.027;

Peddinti BST, Downs SN, Yan J, Smith SD, Ghiladi RA, Mhetar V, Tocchetto R, Griffiths A, Scholle F, Spontak RJ. Rapid and Repetitive Inactivation of SARS-CoV-2 and Human Coronavirus on Self-Disinfecting Anionic Polymers. Adv Sci (Weinh). 2021 06; 8(11):e2003503. PMID: 34105286; PMCID: PMC7994973; DOI: 10.1002/advs.202003503;

Alfson KJ, Goez-Gazi Y, Gazi M, Staples H, Mattix M, Ticer A, Klaffke B, Stanfield K, Escareno P, Keiser P, Griffiths A, Chou YL, Niemuth N, Meister GT, Cirimotich CM, Carrion R. Development of a Well-Characterized Rhesus Macaque Model of Ebola Virus Disease for Support of Product Development. Microorganisms. 2021 Feb 26; 9(3). PMID: 33652589; PMCID: PMC7996724; DOI: 10.3390/microorganisms9030489;

Atyeo C, Slein MD, Fischinger S, Burke J, Schäfer A, Leist SR, Kuzmina NA, Mire C, Honko A, Johnson R, Storm N, Bernett M, Tong P, Zuo T, Lin J, Zuiani A, Linde C, Suscovich T, Wesemann DR, Griffiths A, Desjarlais JR, Juelg BD, Goudsmit J, Bukreyev A, Baric R, Alter G. Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022. JCI Insight. 2021 01 11; 6(1).View Related Profiles.

Honko, Anna
Griffiths, Anthony
Storm, Nadia

PMID: 33427208; PMCID: PMC7821590; DOI: 10.1172/jci.insight.143129;

Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat Struct Mol Biol. 2021 02; 28(2):202-209.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay
Storm, Nadia

PMID: 33432247; PMCID: PMC7895301; DOI: 10.1038/s41594-020-00549-3;

Zabaleta N, Dai W, Bhatt U, Chichester JA, Estelien R, Sanmiguel J, Michalson KT, Diop C, Maciorowski D, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Vandenberghe LH. Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates. bioRxiv. 2021 Jan 05.View Related Profiles.

Honko, Anna
Griffiths, Anthony
Storm, Nadia

PMID: 33442684; PMCID: PMC7805441; DOI: 10.1101/2021.01.05.422952;

Storm N, McKay LGA, Downs SN, Johnson RI, Birru D, de Samber M, Willaert W, Cennini G, Griffiths A. Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation. Sci Rep. 2020 12 30; 10(1):22421.View Related Profiles.

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McKay, Lindsay
Storm, Nadia
Johnson, Rebecca

PMID: 33380727; PMCID: PMC7773738; DOI: 10.1038/s41598-020-79600-8;

Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Griffiths A, Abraham J. Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. bioRxiv. 2020 Nov 13.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay

PMID: 33200128; PMCID: PMC7668731; DOI: 10.1101/2020.11.13.381533;

Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro. bioRxiv. 2020 Sep 18.View Related Profiles.

Griffiths, Anthony
McKay, Lindsay
Storm, Nadia

PMID: 32995768; PMCID: PMC7523094; DOI: 10.1101/2020.09.18.301952;

Kuhn JH, Adkins S, Alioto D, Alkhovsky SV, Amarasinghe GK, Anthony SJ, Avšic-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bartonicka T, Basler C, Bavari S, Beer M, Bente DA, Bergeron É, Bird BH, Blair C, Blasdell KR, Bradfute SB, Breyta R, Briese T, Brown PA, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Buzkan N, Calisher CH, Cao M, Casas I, Chamberlain J, Chandran K, Charrel RN, Chen B, Chiumenti M, Choi IR, Clegg JCS, Crozier I, da Graça JV, Dal Bó E, Dávila AMR, de la Torre JC, de Lamballerie X, de Swart RL, Di Bello PL, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolja VV, Dolnik O, Drebot MA, Drexler JF, Dürrwald R, Dufkova L, Dundon WG, Duprex WP, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K, Fernandes J, Fooks AR, Formenty PBH, Forth LF, Fouchier RAM, Freitas-Astúa J, Gago-Zachert S, Gao GF, García ML, García-Sastre A, Garrison AR, Gbakima A, Goldstein T, Gonzalez JJ, Griffiths A, Groschup MH, Günther S, Guterres A, Hall RA, Hammond J, Hassan M, Hepojoki J, Hepojoki S, Hetzel U, Hewson R, Hoffmann B, Hongo S, Höper D, Horie M, Hughes HR, Hyndman TH, Jambai A, Jardim R, Jiang D, Jin Q, Jonson GB, Junglen S, Karadag S, Keller KE, Klempa B, Klingström J, Kobinger G, Kondo H, Koonin EV, Krupovic M, Kurath G, Kuzmin IV, Laenen L, Lamb RA, Lambert AJ, Langevin SL, Lee B, Lemos ERS, Leroy EM, Li D, Li J, Liang M, Liú W, Liú Y, Lukashevich IS, Maes P, Marciel de Souza W, Marklewitz M, Marshall SH, Martelli GP, Martin RR, Marzano SL, Massart S, McCauley JW, Mielke-Ehret N, Minafra A, Minutolo M, Mirazimi A, Mühlbach HP, Mühlberger E, Naidu R, Natsuaki T, Navarro B, Navarro JA, Netesov SV, Neumann G, Nowotny N, Nunes MRT, Nylund A, Økland AL, Oliveira RC, Palacios G, Pallas V, Pályi B, Papa A, Parrish CR, Pauvolid-Corrêa A, Paweska JT, Payne S, Pérez DR, Pfaff F, Radoshitzky SR, Rahman AU, Ramos-González PL, Resende RO, Reyes CA, Rima BK, Romanowski V, Robles Luna G, Rota P, Rubbenstroth D, Runstadler JA, Ruzek D, Sabanadzovic S, Salát J, Sall AA, Salvato MS, Sarpkaya K, Sasaya T, Schwemmle M, Shabbir MZ, Shí X, Shí Z, Shirako Y, Simmonds P, Širmarová J, Sironi M, Smither S, Smura T, Song JW, Spann KM, Spengler JR, Stenglein MD, Stone DM, Straková P, Takada A, Tesh RB, Thornburg NJ, Tomonaga K, Tordo N, Towner JS, Turina M, Tzanetakis I, Ulrich RG, Vaira AM, van den Hoogen B, Varsani A, Vasilakis N, Verbeek M, Wahl V, Walker PJ, Wang H, Wang J, Wang X, Wang LF, Wèi T, Wells H, Whitfield AE, Williams JV, Wolf YI, Wú Z, Yang X, Yáng X, Yu X, Yutin N, Zerbini FM, Zhang T, Zhang YZ, Zhou G, Zhou X. 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2020 Dec; 165(12):3023-3072.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke
Duprex, William

PMID: 32888050; PMCID: PMC7606449; DOI: 10.1007/s00705-020-04731-2;

Zhang Q, Honko A, Zhou J, Gong H, Downs SN, Vasquez JH, Fang RH, Gao W, Griffiths A, Zhang L. Cellular Nanosponges Inhibit SARS-CoV-2 Infectivity. Nano Lett. 2020 07 08; 20(7):5570-5574.View Related Profiles.

Honko, Anna
Griffiths, Anthony

PMID: 32551679; PMCID: PMC7301960; DOI: 10.1021/acs.nanolett.0c02278;

Johnson DM, Jokinen JD, Wang M, Pfeffer T, Tretyakova I, Carrion R, Griffiths A, Pushko P, Lukashevich IS. Bivalent Junin & Machupo experimental vaccine based on alphavirus RNA replicon vector. Vaccine. 2020 03 23; 38(14):2949-2959. PMID: 32111526; PMCID: PMC7112472; DOI: 10.1016/j.vaccine.2020.02.053;

Jacob ST, Crozier I, Fischer WA, Hewlett A, Kraft CS, Vega MA, Soka MJ, Wahl V, Griffiths A, Bollinger L, Kuhn JH. Ebola virus disease. Nat Rev Dis Primers. 2020 02 20; 6(1):13. PMID: 32080199; PMCID: PMC7223853; DOI: 10.1038/s41572-020-0147-3;

Amarasinghe GK, Ayllón MA, Bào Y, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chabi-Jesus C, Chandran K, Chiapponi C, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Griffiths A, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lavazza A, Lee B, Lelli D, Leroy EM, Li J, Maes P, Marzano SL, Moreno A, Mühlberger E, Netesov SV, Nowotny N, Nylund A, Økland AL, Palacios G, Pályi B, Paweska JT, Payne SL, Prosperi A, Ramos-González PL, Rima BK, Rota P, Rubbenstroth D, Shi M, Simmonds P, Smither SJ, Sozzi E, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang LF, Whitfield AE, Williams JV, Zerbini FM, Zhang T, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2019. Arch Virol. 2019 Jul; 164(7):1967-1980.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke
Duprex, William

PMID: 31089958; PMCID: PMC6641539; DOI: 10.1007/s00705-019-04247-4;

Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, Palacios G, Pályi B, Paweska JT, Smither SJ, Takada A, Towner JS, Wahl V, ICTV Report Consortium. ICTV Virus Taxonomy Profile: Filoviridae. J Gen Virol. 2019 06; 100(6):911-912.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke

PMID: 31021739; PMCID: PMC7011696; DOI: 10.1099/jgv.0.001252;

Zhou M, Humbert M, Mukhtar MM, Scinto HB, Vyas HK, Lakhashe SK, Byrareddy SN, Maurer G, Thorat S, Owuor J, Lai Z, Chen Y, Griffiths A, Chenine AL, Gumber S, Villinger F, Montefiori D, Ruprecht RM. Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade A Envelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants. J Virol. 2019 05 01; 93(9). PMID: 30760566; PMCID: PMC6475780; DOI: 10.1128/JVI.02267-18;

Maes P, Amarasinghe GK, Ayllón MA, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chandran K, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Domier LL, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Ghedin E, Griffiths A, Hewson R, Horie M, Hurwitz JL, Hyndman TH, Jiang D, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lee B, Leroy EM, Li J, Marzano SL, Mühlberger E, Netesov SV, Nowotny N, Palacios G, Pályi B, Paweska JT, Payne SL, Rima BK, Rota P, Rubbenstroth D, Simmonds P, Smither SJ, Song Q, Song T, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang D, Wang LF, Whitfield AE, Williams JV, Yè G, Zerbini FM, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: second update 2018. Arch Virol. 2019 Apr; 164(4):1233-1244.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke
Duprex, William

PMID: 30663023; PMCID: PMC6460460; DOI: 10.1007/s00705-018-04126-4;

Qin P, Park M, Alfson KJ, Tamhankar M, Carrion R, Patterson JL, Griffiths A, He Q, Yildiz A, Mathies R, Du K. Rapid and Fully Microfluidic Ebola Virus Detection with CRISPR-Cas13a. ACS Sens. 2019 04 26; 4(4):1048-1054. PMID: 30860365

Alfson KJ, Avena LE, Beadles MW, Worwa G, Amen M, Patterson JL, Carrion R, Griffiths A. Intramuscular Exposure of Macaca fascicularis to Low Doses of Low Passage- or Cell Culture-Adapted Sudan Virus or Ebola Virus. Viruses. 2018 11 16; 10(11). PMID: 30453499; PMCID: PMC6267154; DOI: 10.3390/v10110642;

Scinto HB, Gupta S, Thorat S, Mukhtar MM, Griffiths A, Delgado J, Plake E, Vyas HK, Strickland A, Byrareddy SN, Montefiori DC, LaBranche C, Pal R, Treece J, Orndorff S, Ferrari MG, Weiss D, Chenine AL, McLinden R, Michael N, Kim JH, Robb ML, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Ruprecht RM. Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying env from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism. J Virol. 2018 07 15; 92(14). PMID: 29743361; PMCID: PMC6026739; DOI: 10.1128/JVI.02222-17;

Alfson KJ, Griffiths A. Development and Testing of a Method for Validating Chemical Inactivation of Ebola Virus. Viruses. 2018 03 13; 10(3). PMID: 29533988; PMCID: PMC5869519; DOI: 10.3390/v10030126;

Alfson KJ, Avena LE, Delgado J, Beadles MW, Patterson JL, Carrion R, Griffiths A. A Single Amino Acid Change in the Marburg Virus Glycoprotein Arises during Serial Cell Culture Passages and Attenuates the Virus in a Macaque Model of Disease. mSphere. 2018 Jan-Feb; 3(1). PMID: 29299527; PMCID: PMC5750385; DOI: 10.1128/mSphere.00401-17;

Du K, Park M, Griffiths A, Carrion R, Patterson J, Schmidt H, Mathies R. Microfluidic System for Detection of Viral RNA in Blood Using a Barcode Fluorescence Reporter and a Photocleavable Capture Probe. Anal Chem. 2017 11 21; 89(22):12433-12440. PMID: 29073356; PMCID: PMC5990416; DOI: 10.1021/acs.analchem.7b03527;

Alfson KJ, Avena LE, Worwa G, Carrion R, Griffiths A. Development of a Lethal Intranasal Exposure Model of Ebola Virus in the Cynomolgus Macaque. Viruses. 2017 10 29; 9(11). PMID: 29109373; PMCID: PMC5707526; DOI: 10.3390/v9110319;

Harden ME, Prasad N, Griffiths A, Munger K. Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins. MBio. 2017 01 03; 8(1). PMID: 28049151; PMCID: PMC5210503; DOI: 10.1128/mBio.02170-16;

Du K, Cai H, Park M, Wall TA, Stott MA, Alfson KJ, Griffiths A, Carrion R, Patterson JL, Hawkins AR, Schmidt H, Mathies RA. Multiplexed efficient on-chip sample preparation and sensitive amplification-free detection of Ebola virus. Biosens Bioelectron. 2017 May 15; 91:489-496. PMID: 28073029; PMCID: PMC5323362; DOI: 10.1016/j.bios.2016.12.071;

Cnops L, van Griensven J, Honko AN, Bausch DG, Sprecher A, Hill CE, Colebunders R, Johnson JC, Griffiths A, Palacios GF, Kraft CS, Kobinger G, Hewlett A, Norwood DA, Sabeti P, Jahrling PB, Formenty P, Kuhn JH, Ariën KK. Overlooking the importance of immunoassays - Authors' reply. Lancet Infect Dis. 2016 10; 16(10):1110.View Related Profiles.

Honko, Anna
Griffiths, Anthony

PMID: 27676345; DOI: 10.1016/S1473-3099(16)30339-5;

Cnops L, van Griensven J, Honko AN, Bausch DG, Sprecher A, Hill CE, Colebunders R, Johnson JC, Griffiths A, Palacios GF, Kraft CS, Kobinger G, Hewlett A, Norwood DA, Sabeti P, Jahrling PB, Formenty P, Kuhn JH, Ariën KK. Essentials of filoviral load quantification. Lancet Infect Dis. 2016 07; 16(7):e134-e138.View Related Profiles.

Honko, Anna
Griffiths, Anthony

PMID: 27296694; DOI: 10.1016/S1473-3099(16)30063-9;

Sanabria-Solano C, Gonzalez CE, Richerioux N, Bertrand L, Dridi S, Griffiths A, Langelier Y, Pearson A. Regulation of viral gene expression by the herpes simplex virus 1UL24 protein (HSV-1UL24 inhibits accumulation of viral transcripts). Virology. 2016 08; 495:148-60. PMID: 27214229; DOI: 10.1016/j.virol.2016.05.006;

Alfson KJ, Worwa G, Carrion R, Griffiths A. Determination and Therapeutic Exploitation of Ebola Virus Spontaneous Mutation Frequency. J Virol. 2015 Dec 16; 90(5):2345-55. PMID: 26676781; PMCID: PMC4810732; DOI: 10.1128/JVI.02701-15;

Colgrove RC, Liu X, Griffiths A, Raja P, Deluca NA, Newman RM, Coen DM, Knipe DM. History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains. Virology. 2016 Jan; 487:215-21. PMID: 26547038; PMCID: PMC4679709; DOI: 10.1016/j.virol.2015.09.026;

Cai H, Parks JW, Wall TA, Stott MA, Stambaugh A, Alfson K, Griffiths A, Mathies RA, Carrion R, Patterson JL, Hawkins AR, Schmidt H. Optofluidic analysis system for amplification-free, direct detection of Ebola infection. Sci Rep. 2015 Sep 25; 5:14494. PMID: 26404403; PMCID: PMC4585921; DOI: 10.1038/srep14494;

Alfson KJ, Avena LE, Beadles MW, Staples H, Nunneley JW, Ticer A, Dick EJ, Owston MA, Reed C, Patterson JL, Carrion R, Griffiths A. Particle-to-PFU ratio of Ebola virus influences disease course and survival in cynomolgus macaques. J Virol. 2015 Jul; 89(13):6773-81. PMID: 25903348; PMCID: PMC4468478; DOI: 10.1128/JVI.00649-15;

Lee MH, Rostal MK, Hughes T, Sitam F, Lee CY, Japning J, Harden ME, Griffiths A, Basir M, Wolfe ND, Epstein JH, Daszak P. Macacine Herpesvirus 1 in Long-Tailed Macaques, Malaysia, 2009-2011. Emerg Infect Dis. 2015 Jul; 21(7):1107-13. PMID: 26080081; PMCID: PMC4480374; DOI: 10.3201/eid2107.140162;

Alfson KJ, Avena LE, Beadles MW, Menzie H, Patterson JL, Carrion R, Griffiths A. Genetic Changes at the Glycoprotein Editing Site Associated With Serial Passage of Sudan Virus. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S295-304. PMID: 25920319; PMCID: PMC6283357; DOI: 10.1093/infdis/jiv216;

Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses. 2014 Sep; 6(9):3663-82.View Related Profiles.

Honko, Anna
Griffiths, Anthony
Muhlberger, Elke
Olinger, Gene
Sullivan, Nancy
Davey, Robert

PMID: 25256396; PMCID: PMC4189044; DOI: 10.3390/v6093663;

Alfson KJ, Beadles MW, Griffiths A. A new approach to determining whole viral genomic sequences including termini using a single deep sequencing run. J Virol Methods. 2014 Nov; 208:1-5. PMID: 25075935; DOI: 10.1016/j.jviromet.2014.07.023;

Griffiths A, Hayhurst A, Davey R, Shtanko O, Carrion R, Jr., Patterson JL. Viral hemorrhagic fevers. Ebola virus infection. CRC Press. Boca Raton. 2014; 435-456.

Shurtleff AC, Biggins JE, Keeney AE, Zumbrun EE, Bloomfield HA, Kuehne A, Audet JL, Alfson KJ, Griffiths A, Olinger GG, Bavari S. Standardization of the filovirus plaque assay for use in preclinical studies. Viruses. 2012 Dec; 4(12):3511-30.View Related Profiles.

Griffiths, Anthony
Olinger, Gene

PMID: 23223188; PMCID: PMC3528277; DOI: 10.3390/v4123511;

Shurtleff AC, Garza N, Lackemeyer M, Carrion R, Griffiths A, Patterson J, Edwin SS, Bavari S. The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment. Viruses. 2012 Dec; 4(12):3932-51. PMID: 23342380; PMCID: PMC3528297

Fan Q, Amen M, Harden M, Severini A, Griffiths A, Longnecker R. Herpes B virus utilizes human nectin-1 but not HVEM or PILRa for cell-cell fusion and virus entry. J Virol. 2012 Apr; 86(8):4468-76. PMID: 22345445; PMCID: PMC3318624; DOI: 10.1128/JVI.00041-12;

Amen MA, Griffiths A. Packaging of Non-Coding RNAs into Herpesvirus Virions: Comparisons to Coding RNAs. Front Genet. 2011; 2:81. PMID: 22303375; PMCID: PMC3268634; DOI: 10.3389/fgene.2011.00081;

Griffiths A. Slipping and sliding: frameshift mutations in herpes simplex virus thymidine kinase and drug-resistance. Drug Resist Updat. 2011 Dec; 14(6):251-9. PMID: 21940196; PMCID: PMC3195865; DOI: 10.1016/j.drup.2011.08.003;

Jurak I, Griffiths A, Coen DM. Mammalian alphaherpesvirus miRNAs. Biochim Biophys Acta. 2011 Nov-Dec; 1809(11-12):641-53. PMID: 21736960; PMCID: PMC3382970; DOI: 10.1016/j.bbagrm.2011.06.010;

Amen MA, Griffiths A. Identification and expression analysis of herpes B virus-encoded small RNAs. J Virol. 2011 Jul; 85(14):7296-311. PMID: 21543500; PMCID: PMC3126578; DOI: 10.1128/JVI.00505-11;

Griffiths, A., R. Carrion, Jr., J.A. Miller, H. Sasinowska, M. Sasinowski, and J.L. Patterson. An electronic inventory system designed to aid compliance with the National Select Agents Registry Program. 2011; (16):9-18.

Besecker MI, Harden ME, Li G, Wang XJ, Griffiths A. Discovery of herpes B virus-encoded microRNAs. J Virol. 2009 Apr; 83(7):3413-6. PMID: 19144716; PMCID: PMC2655578; DOI: 10.1128/JVI.02419-08;

Besecker MI, Furness CL, Coen DM, Griffiths A. Expression of extremely low levels of thymidine kinase from an acyclovir-resistant herpes simplex virus mutant supports reactivation from latently infected mouse trigeminal ganglia. J Virol. 2007 Aug; 81(15):8356-60. PMID: 17522225; PMCID: PMC1951311; DOI: 10.1128/JVI.00484-07;

Chen SH, Lin YW, Griffiths A, Huang WY, Chen SH. Competition and complementation between thymidine kinase-negative and wild-type herpes simplex virus during co-infection of mouse trigeminal ganglia. J Gen Virol. 2006 Dec; 87(Pt 12):3495-502. PMID: 17098963; DOI: 10.1099/vir.0.82223-0;

Griffiths A, Link MA, Furness CL, Coen DM. Low-level expression and reversion both contribute to reactivation of herpes simplex virus drug-resistant mutants with mutations on homopolymeric sequences in thymidine kinase. J Virol. 2006 Jul; 80(13):6568-74. PMID: 16775343; PMCID: PMC1488940; DOI: 10.1128/JVI.00155-06;

Cui C, Griffiths A, Li G, Silva LM, Kramer MF, Gaasterland T, Wang XJ, Coen DM. Prediction and identification of herpes simplex virus 1-encoded microRNAs. J Virol. 2006 Jun; 80(11):5499-508. PMID: 16699030; PMCID: PMC1472173; DOI: 10.1128/JVI.00200-06;

Griffiths A, Coen DM. An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9667-72. PMID: 15972803; PMCID: PMC1172279; DOI: 10.1073/pnas.0504132102;

Griffiths A, Chen SH, Horsburgh BC, Coen DM. Translational compensation of a frameshift mutation affecting herpes simplex virus thymidine kinase is sufficient to permit reactivation from latency. J Virol. 2003 Apr; 77(8):4703-9. PMID: 12663777; PMCID: PMC152167

Griffiths A, Coen DM. High-frequency phenotypic reversion and pathogenicity of an acyclovir-resistant herpes simplex virus mutant. J Virol. 2003 Feb; 77(3):2282-6. PMID: 12525666; PMCID: PMC140925

Griffiths A, Renfrey S, Minson T. Glycoprotein C-deficient mutants of two strains of herpes simplex virus type 1 exhibit unaltered adsorption characteristics on polarized or non-polarized cells. J Gen Virol. 1998 Apr; 79 ( Pt 4):807-12. PMID: 9568976; DOI: 10.1099/0022-1317-79-4-807;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 76 publications over 18 distinct years, with a maximum of 14 publications in 2021

Bar chart showing 76 publications over 18 distinct years, with a maximum of 14 publications in 2021

Year	Publications
1998	1
2003	2
2005	1
2006	3
2007	1
2009	1
2011	5
2012	3
2014	3
2015	6
2016	3
2017	4
2018	4
2019	5
2020	7
2021	14
2022	11
2023	2

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