Deborah J. Stearns-Kurosawa, PhD
Associate Professor
Boston University School of Medicine
Dept of Pathology & Laboratory Medicine

PhD, Cleveland State University



Expertise in the development and characterization of animal models of infectious disease to identify host-pathogen interactions and evidence-based therapeutic interventions.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Evaluating the Impact of delayed administration of Shigamb (anti-Stx2) antibody on development of Stx2-in
02/01/2015 - 03/31/2017 (PI)
BELLUS Health Inc.





Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Hall G, Kurosawa S, Stearns-Kurosawa DJ. Shiga Toxin Therapeutics: Beyond Neutralization. Toxins (Basel). 2017 Sep 19; 9(9).View Related Profiles. PMID: 28925976.
  2. Mayer CL, Parello CS, Lee BC, Itagaki K, Kurosawa S, Stearns-Kurosawa DJ. Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns. Front Immunol. 2015; 6:155.View Related Profiles. PMID: 25904918; DOI: 10.3389/fimmu.2015.00155;.
  3. Parello CS, Mayer CL, Lee BC, Motomochi A, Kurosawa S, Stearns-Kurosawa DJ. Shiga toxin 2-induced endoplasmic reticulum stress is minimized by activated protein C but does not correlate with lethal kidney injury. Toxins (Basel). 2015 Jan; 7(1):170-86.View Related Profiles. PMID: 25609181; PMCID: PMC4303821; DOI: 10.3390/toxins7010170;.
  4. Kurosawa S, Stearns-Kurosawa DJ. Complement, thrombotic microangiopathy and disseminated intravascular coagulation. J Intensive Care. 2014; 2(1):65.View Related Profiles. PMID: 25705421; DOI: 10.1186/s40560-014-0061-4;.
  5. Iskander KN, Osuchowski MF, Stearns-Kurosawa DJ, Kurosawa S, Stepien D, Valentine C, Remick DG. Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding. Physiol Rev. 2013 Jul; 93(3):1247-88.View Related Profiles. PMID: 23899564; DOI: 10.1152/physrev.00037.2012;.
  6. Lee BC, Mayer CL, Leibowitz CS, Stearns-Kurosawa DJ, Kurosawa S. Quiescent complement in nonhuman primates during E coli Shiga toxin-induced hemolytic uremic syndrome and thrombotic microangiopathy. Blood. 2013 Aug 1; 122(5):803-6.View Related Profiles. PMID: 23733336; PMCID: PMC3731933; DOI: 10.1182/blood-2013-03-490060;.
  7. Stearns-Kurosawa DJ, Oh SY, Cherla RP, Lee MS, Tesh VL, Papin J, Henderson J, Kurosawa S. Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome. Am J Pathol. 2013 Apr; 182(4):1227-38.View Related Profiles. PMID: 23402998; PMCID: PMC3620421; DOI: 10.1016/j.ajpath.2012.12.026;.
  8. Sursal T, Stearns-Kurosawa DJ, Itagaki K, Oh SY, Sun S, Kurosawa S, Hauser CJ. Plasma bacterial and mitochondrial DNA distinguish bacterial sepsis from sterile systemic inflammatory response syndrome and quantify inflammatory tissue injury in nonhuman primates. Shock. 2013 Jan; 39(1):55-62.View Related Profiles. PMID: 23247122; PMCID: PMC3537509; DOI: 10.1097/SHK.0b013e318276f4ca;.
  9. Mayer CL, Leibowitz CS, Kurosawa S, Stearns-Kurosawa DJ. Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals. Toxins (Basel). 2012 Nov; 4(11):1261-87.View Related Profiles. PMID: 23202315; PMCID: PMC3509707; DOI: 10.3390/toxins4111261;.
  10. Ghosh CC, Mukherjee A, David S, Knaus UG, Stearns-Kurosawa DJ, Kurosawa S, Parikh SM. Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):10024-9.View Related Profiles. PMID: 22665799; PMCID: PMC3382507; DOI: 10.1073/pnas.1120755109;.
Showing 10 of 37 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 37 publications over 19 distinct years, with a maximum of 4 publications in 2013

YearPublications
19941
19963
19972
19982
19993
20002
20022
20032
20051
20062
20072
20082
20101
20112
20122
20134
20141
20152
20171
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

infectious disease
nonhuman primate models
pre-clinical models
sepsis
Contact for Mentoring:


670 Albany St Biosquare III
Boston MA 02118
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