Lewina Lee | Profiles RNS

Lewina Lee, PhD

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Psychiatry

General Psychiatry

PhD, University of Southern California
MA, University of Southern California
BA, University of Southern California

Websites

	Twitter
	National Center for Posttraumatic Stress Disorder Profile
	LinkedIn
	Google Scholar

ORCID : 0000-0002-1652-8198

Lewina O. Lee, PhD, is Associate Professor of Psychiatry at the Chobanian and Avedisian School of Medicine, and Psychologist-Clinical Investigator at the National Center for Posttraumatic Stress at the Veterans Affairs (VA) Boston Healthcare System. She received her Ph.D. (Clinical Psychology–Aging) from the University of Southern California. She completed a Clinical Psychology internship at VA Palo Alto and a postdoctoral fellowship in Epidemiology at Boston University and VA Boston. Her research examines the role of psychosocial stress exposure – particularly early adversity – on lifespan health, and mechanisms which transmit the effects of stress on health, while adopting a lifespan developmental perspective. A related line of her research considers positive psychosocial factors which confer resilience against the effects of psychosocial stress exposure on health. She co-directs the Boston Early Adversity and Mortality Study (BEAMS), which aims to create a cradle-to-grave dataset to enable research on lifespan processes linking childhood experiences to later-life health. She has been the recipient of numerous awards from the National Institute on Aging, including a predoctoral NRSA (F31) fellowship, a Mentored Clinical Scientist Research Career Development Award (K08), and an RF-1 award.

VA Boston Healthcare System

BU Research
NIH RePORTER Research

Boston early Adversity and Mortality Study (BEAMS): Linking administrative data to long-term longitudinal studies
08/11/2023 - 06/30/2024 (Subcontract PI)
Northwestern University NIH NIA
1RF1AG064006-01

Boston Early Adversity and Mortality Study (BEAMS)
08/01/2019 - 06/30/2024 (Multi-PI)
PI: Lewina Lee, PhD
Northwestern University NIH NIA
3RF1AG064006-01S1

Lifespan Effects of Biologically Embedded Stress on Health
09/30/2015 - 04/30/2022 (PI)
NIH/National Institute on Aging
5K08AG048221-05

Personnel Agreement for the Research Services of Lewina Lee
08/01/2015 - 07/31/2016 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Lewina Lee
02/01/2015 - 09/30/2015 (PI)
VA Boston Healthcare System

The Wisconsin Longitudinal Study: Tracking The Life Course
07/01/2012 - 06/15/2014 (Subcontract PI)
University of Wisconsin System NIH NIA
P01AG021079-08

Title

Yr	Title	Project-Sub Proj	Pubs
2023	Boston Early Adversity and Mortality Study (BEAMS): Linking Administrative Data to Long-Term Longitudinal Studies	3RF1AG064006-01S2
2020	Boston Early Adversity and Mortality Study (BEAMS): Linking administrative data to long-term longitudinal studies	3RF1AG064006-01S1	2
2019	Boston Early Adversity and Mortality Study (BEAMS): Linking administrative data to long-term longitudinal studies	1RF1AG064006-01	2
2019	Lifespan Effects of Biologically Embedded Stress on Health	5K08AG048221-05	9
2018	Lifespan Effects of Biologically Embedded Stress on Health	5K08AG048221-04	9
2017	Lifespan Effects of Biologically Embedded Stress on Health	5K08AG048221-03	9
2016	Lifespan Effects of Biologically Embedded Stress on Health	5K08AG048221-02	9
2015	Lifespan Effects of Biologically Embedded Stress on Health	1K08AG048221-01A1	9
2009	Anxiety, Stressful Life Events, and Physical Health in Older Adults	5F31AG031691-02	4
2007	Anxiety, Stressful Life Events, and Physical Health in Older Adults	1F31AG031691-01	4

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Trudel-Fitzgerald C, Lee LO, Guimond AJ, Chen R, James P, Koga HK, Lee HH, Okuzono SS, Grodstein F, Rich-Edwards J, Kubzansky LD. A long and resilient life: the role of coping strategies and variability in their use in lifespan among women. Anxiety Stress Coping. 2024 Jul; 37(4):473-486.View Related Profiles.

Lee, Lewina
Chen, Ruijia

PMID: 38031408; DOI: 10.1080/10615806.2023.2288333;

Atherton OE, Graham EK, Dorame AN, Horgan D, Luo J, Nevarez MD, Ferrie JP, Spiro A, Schulz MS, Waldinger RJ, Mroczek DK, Lee LO. Is there intergenerational continuity in early life experiences? Findings from the Harvard Study of Adult Development. J Fam Psychol. 2023 Dec; 37(8):1123-1136.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 37616090; DOI: 10.1037/fam0001144;

Vasterling JJ, Franz MR, Lee LO, Kaiser AP, Proctor SP, Marx BP, Schnurr PP, Ko J, Concato J, Aslan M. Early predictors of chronic posttraumatic stress disorder symptom trajectories in U.S. Army soldiers deployed to the Iraq war zone. J Trauma Stress. 2023 Oct; 36(5):955-967.View Related Profiles.

Marx, Brian
Vasterling, Jennifer
Lee, Lewina

PMID: 37608526

Vogt D, Kumar SA, Lee LO. PTSD Research Quarterly. Examining functioning and well-being outcomes in PTSD treatment outcome research. 2023; (34):1-9.

Lee LO, Chen R, Mendes WB, Kubzansky LD. Lifespan psychosocial stressors, optimism, and hemodynamic acute stress response in a national sample. Health Psychol. 2023 Mar; 42(3):172-181.View Related Profiles.

Lee, Lewina
Chen, Ruijia

PMID: 36862473; DOI: 10.1037/hea0001276;

Wang C, DeMeo DL, Kim ES, Cardenas A, Fong KC, Lee LO, Spiro A, Whitsel EA, Horvath S, Hou L, Baccarelli AA, Li Y, Stewart JD, Manson JE, Grodstein F, Kubzansky LD, Schwartz JD. Epigenome-Wide Analysis of DNA Methylation and Optimism in Women and Men. Psychosom Med. 2023 01 01; 85(1):89-97.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 36201768; DOI: 10.1097/PSY.0000000000001147;

Trudel-Fitzgerald C, Chen R, Lee LO, Kubzansky LD. Are coping strategies and variability in their use associated with lifespan? J Psychosom Res. 2022 Nov; 162:111035.View Related Profiles.

Lee, Lewina
Chen, Ruijia

PMID: 36152346; DOI: 10.1016/j.jpsychores.2022.111035;

Lee LO, Grodstein F, Trudel-Fitzgerald C, James P, Okuzono SS, Koga HK, Schwartz J, Spiro A, Mroczek DK, Kubzansky LD. Optimism, Daily Stressors, and Emotional Well-Being Over Two Decades in a Cohort of Aging Men. J Gerontol B Psychol Sci Soc Sci. 2022 Aug 11; 77(8):1373-1383.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 35255123; DOI: 10.1093/geronb/gbac025;

Koga HK, Trudel-Fitzgerald C, Lee LO, James P, Kroenke C, Garcia L, Shadyab AH, Salmoirago-Blotcher E, Manson JE, Grodstein F, Kubzansky LD. Optimism, lifestyle, and longevity in a racially diverse cohort of women. J Am Geriatr Soc. 2022 10; 70(10):2793-2804. PMID: 35674052; DOI: 10.1111/jgs.17897;

Chiu C, Gnall K, Kaiser AP, Taft CT, Franz MR, Lee LO, Vasterling JJ. Neurocognitive Performance Predicts Future Partner Violence Among U.S. Iraq-and Afghanistan-deployed Army Soldiers and Veterans. Psychol Violence. 2022 May; 12(3):160-169.View Related Profiles.

Taft, Casey
Vasterling, Jennifer
Lee, Lewina

PMID: 38463935; DOI: 10.1037/vio0000408;

Showing 10 of 47 results. Show More

Lee LO, Grimm KJ, Spiro A, Kubzansky LD. Neuroticism, Worry, and Cardiometabolic Risk Trajectories: Findings From a 40-Year Study of Men. J Am Heart Assoc. 2022 02; 11(3):e022006.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 35072514; DOI: 10.1161/JAHA.121.022006;

Guimond, A-J., Kubzansky, L.D., & Lee, L.O. In R. Schwartz, J.A. Hall, & L.G. Osterberg (Eds.), Emotion in the Clinical Encounter. Emotion and illness. McGraw Hill. New York. 2021; 51-81. View Publication

Lindert J, Lee LO, Weisskopf MG, McKee M, Sehner S, Spiro A. Threats to Belonging-Stressful Life Events and Mental Health Symptoms in Aging Men-A Longitudinal Cohort Study. Front Psychiatry. 2020; 11:575979.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 33424657; DOI: 10.3389/fpsyt.2020.575979;

Yang MS, Quach L, Lee LO, Spiro A, Burr JA. Subjective well-being among male veterans in later life: the enduring effects of early life adversity. Aging Ment Health. 2022 01; 26(1):107-115.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 33170037; DOI: 10.1080/13607863.2020.1842999;

Franz MR, Kaiser AP, Phillips RJ, Lee LO, Lawrence AE, Taft CT, Vasterling JJ. Associations of warzone veteran mental health with partner mental health and family functioning: Family Foundations Study. Depress Anxiety. 2020 11; 37(11):1068-1078.View Related Profiles.

Lawrence, Amy
Taft, Casey
Vasterling, Jennifer
Lee, Lewina

PMID: 32805764; DOI: 10.1002/da.23083;

LaMotte AD, Pless Kaiser A, Lee LO, Supelana C, Taft CT, Vasterling JJ. Factors Influencing Family Environment Reporting Concordance Among U.S. War Zone Veterans and Their Partners. Assessment. 2021 07; 28(5):1459-1470.View Related Profiles.

Pless Kaiser, Anica
Taft, Casey
Vasterling, Jennifer
Lee, Lewina

PMID: 32486907; DOI: 10.1177/1073191120922619;

Lee DJ, Lee LO, Bovin MJ, Moshier SJ, Dutra SJ, Kleiman SE, Rosen RC, Vasterling JJ, Keane TM, Marx BP. The 20-year course of posttraumatic stress disorder symptoms among veterans. J Abnorm Psychol. 2020 Aug; 129(6):658-669.View Related Profiles.

Marx, Brian
Vasterling, Jennifer
Lee, Lewina
Bovin, Michelle
Dutra, Sunny
Keane, Terence

PMID: 32478530; DOI: 10.1037/abn0000571;

Lee, L. O. PTSD Research Quarterly. PTSD and Aging. 2019; 30(4):1-15.

Lee LO, Aldwin CM, Kubzansky LD, Mroczek DK, Spiro A. The long arm of childhood experiences on longevity: Testing midlife vulnerability and resilience pathways. Psychol Aging. 2019 Nov; 34(7):884-899.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 31524422; DOI: 10.1037/pag0000394;

Lee LO, James P, Zevon ES, Kim ES, Trudel-Fitzgerald C, Spiro A, Grodstein F, Kubzansky LD. Optimism is associated with exceptional longevity in 2 epidemiologic cohorts of men and women. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18357-18362.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 31451635; DOI: 10.1073/pnas.1900712116;

Kim ES, Fong K, Lee L, Spiro A, Schwartz J, Whitsel E, Horvath S, Wang C, Hou L, Baccarelli AA, Li Y, Stewart J, Manson JE, Grodstein F, DeMeo DL, Kubzansky LD. Optimism is not associated with two indicators of DNA methylation aging. Aging (Albany NY). 2019 07 18; 11(14):4970-4989.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 31322503; DOI: 10.18632/aging.102090;

Duggan, E. C., Piccinin, A. M., Clouston, S., Koval, A. V., Robitalle, A., Zammit, A. R., Wu, C., Brown, C. L., Lee, L. O., Finkel, D., Beasley, W. H., Kaye, J., Muniz Terrera, G., Katz, M., Lipton, R. B., Deeg, D., Bennett, D. A., Praetorius Björk, M., Johansson, B., Spiro III, A., Weuve, J., & Hofer, S. M. (in press). A multi-study coordinated meta-analysis of pulmonary function and cognition in aging. The Journals of Gerontology Series A: Medical Sciences. 2019. View Publication
Lee LO, Rouse S, & Mlinac MM. Home-based assessment and treatment of OCD symptoms to reduce unnecessary emergency room usage in an older adult. Journal of Cognitive Psychotherapy. 2019; 33(1):82-94.

Japuntich SJ, Lee LO, Pineles SL, Gregor K, Joos CM, Patton SC, Krishnan-Sarin S, Rasmusson AM. Contingency management and cognitive behavioral therapy for trauma-exposed smokers with and without posttraumatic stress disorder. Addict Behav. 2019 03; 90:136-142.View Related Profiles.

Rasmusson, Ann
Gregor, Kristin
Lee, Lewina
Pineles, Suzanne

PMID: 30391774; DOI: 10.1016/j.addbeh.2018.10.042;

Cahana-Amitay D, Lee LO, Spiro A, Albert ML. Breathe Easy, Speak Easy: Pulmonary Function and Language Performance in Aging. Exp Aging Res. 2018 Oct-Dec; 44(5):351-368.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 30355179; DOI: 10.1080/0361073X.2018.1521374;

Lee LO, Spiro A III, King DW, & King LA. In Avron Spiro, III., Richard A. Settersten, & Carolyn M. Aldwin (Eds.), Long-term outcomes of military service: The health and well-being of aging veterans. Studying longitudinal links from early adult adversity to later-life well-being: American repatriated prisoners of the Vietnam war. American Psychological Association. Washington, DC. 2018.

Vasterling JJ, Aslan M, Lee LO, Proctor SP, Ko J, Jacob S, Concato J. Longitudinal Associations among Posttraumatic Stress Disorder Symptoms, Traumatic Brain Injury, and Neurocognitive Functioning in Army Soldiers Deployed to the Iraq War. J Int Neuropsychol Soc. 2018 04; 24(4):311-323.View Related Profiles.

Vasterling, Jennifer
Lee, Lewina

PMID: 29199924; DOI: 10.1017/S1355617717001059;

Mitchell KS, Wolf EJ, Bovin MJ, Lee LO, Green JD, Rosen RC, Keane TM, Marx BP. Network models of DSM-5 posttraumatic stress disorder: Implications for ICD-11. J Abnorm Psychol. 2017 Apr; 126(3):355-366.View Related Profiles.

Marx, Brian
Wolf, Erika
Green, Jonathan D
Mitchell, Karen
Lee, Lewina
Bovin, Michelle
Keane, Terence

PMID: 28191985; DOI: 10.1037/abn0000252;

Verfaellie M, Lee LO, Lafleche G, Spiro A. Self-Reported Sleep Disturbance Mediates the Relationship Between PTSD and Cognitive Outcome in Blast-Exposed OEF/OIF Veterans. J Head Trauma Rehabil. 2016 Sep-Oct; 31(5):309-19.View Related Profiles.

Spiro, Avron
Lee, Lewina
Verfaellie, Mieke

PMID: 26580692; DOI: 10.1097/HTR.0000000000000197;

Wolf EJ, Bovin MJ, Green JD, Mitchell KS, Stoop TB, Barretto KM, Jackson CE, Lee LO, Fang SC, Trachtenberg F, Rosen RC, Keane TM, Marx BP. Longitudinal associations between post-traumatic stress disorder and metabolic syndrome severity. Psychol Med. 2016 Jul; 46(10):2215-26.View Related Profiles.

Marx, Brian
Jackson, Colleen
Wolf, Erika
Lee, Lewina
Bovin, Michelle
Keane, Terence

PMID: 27087657; PMCID: PMC4925183; DOI: 10.1017/S0033291716000817;

Lee LO, Gatz M, Pedersen NL, Prescott CA. Anxiety trajectories in the second half of life: Genetic and environmental contributions over age. Psychol Aging. 2016 Feb; 31(1):101-13. PMID: 26751006; PMCID: PMC4752394; DOI: 10.1037/pag0000063;

McFarland CP, Clark JB, Lee LO, Grande LJ, Marx BP, Vasterling JJ. Event-based prospective memory among veterans: The role of posttraumatic stress disorder symptom severity in executing intentions. J Clin Exp Neuropsychol. 2016; 38(2):251-60.View Related Profiles.

Marx, Brian
Vasterling, Jennifer
Grande, Laura
Lee, Lewina

PMID: 26691304; DOI: 10.1080/13803395.2015.1102203;

Lee LO, Aldwin CM, Kubzansky LD, Chen E, Mroczek DK, Wang JM, Spiro A. Do cherished children age successfully? Longitudinal findings from the Veterans Affairs Normative Aging Study. Psychol Aging. 2015 Dec; 30(4):894-910.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 26436456; DOI: 10.1037/pag0000050;

Vasterling JJ, Taft CT, Proctor SP, Macdonald HZ, Lawrence A, Kalill K, Kaiser AP, Lee LO, King DW, King LA, Fairbank JA. Establishing a methodology to examine the effects of war-zone PTSD on the family: the family foundations study. Int J Methods Psychiatr Res. 2015 Jun; 24(2):143-55.View Related Profiles.

Lawrence, Amy
Taft, Casey
King, Daniel
Vasterling, Jennifer
Lee, Lewina

PMID: 26077194; PMCID: PMC4470319; DOI: 10.1002/mpr.1464;

King DW, King LA, Park CL, Lee LO, Kaiser AP, Spiro A, Moore JL, Kaloupek DG, Keane TM. Positive Adjustment Among American Repatriated Prisoners of the Vietnam War: Modeling the Long-Term Effects of Captivity. Clin Psychol Sci. 2015 Nov 01; 3(6):861-876.View Related Profiles.

Spiro, Avron
King, Daniel
Kaloupek, Danny
Lee, Lewina
Keane, Terence

PMID: 26693100; DOI: 10.1177/2167702614554448;

Wang JM, Lee LO, Spiro A. Gender differences in the impact of warfare exposure on self-rated health. Womens Health Issues. 2015 Jan-Feb; 25(1):35-41.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 25442366; PMCID: PMC4275340; DOI: 10.1016/j.whi.2014.09.003;

Han SC, Castro F, Lee LO, Charney ME, Marx BP, Brailey K, Proctor SP, Vasterling JJ. Military unit support, postdeployment social support, and PTSD symptoms among active duty and National Guard soldiers deployed to Iraq. J Anxiety Disord. 2014 Jun; 28(5):446-53.View Related Profiles.

Marx, Brian
Castro, Frank
Vasterling, Jennifer
Brailey, Kevin
Lee, Lewina

PMID: 24846492; DOI: 10.1016/j.janxdis.2014.04.004;

Lee LO, Prescott CA. Association of the catechol-O-methyltransferase val158met polymorphism and anxiety-related traits: a meta-analysis. Psychiatr Genet. 2014 Apr; 24(2):52-69. PMID: 24300663; PMCID: PMC3991696; DOI: 10.1097/YPG.0000000000000018;

King DW, King LA, Kaiser AP, & Lee LO. In TM Keane, PA Resick, & MJ Friedman (Eds.), PTSD: Science and Practice – A Comprehensive Handbook. Advances in design and analysis in trauma research. Guilford Press. New York. 2014; pp. 81-99..
Chun M, Lee LO, & Knight BG. In RC Talley & SS Travis (Eds.), Multi-disciplinary Coordinated Caregiving: Professional Contributions. Professional gerontology and caregiving. Springer. New York. 2014; pp. 31-50.

Kaiser AP, Spiro A, Lee LO, Stellman JM. Women Vietnam Veterans: Do PTSD Symptoms Mediate Effects of Warzone Service on Health? Res Hum Dev. 2012; 9(3):210-228.View Related Profiles.

Spiro, Avron
Lee, Lewina

PMID: 22984348; DOI: 10.1080/15427609.2012.705553;

Lee LO, Young-Wolff KC, Wolff KC, Kendler KS, Prescott CA. The effects of age at drinking onset and stressful life events on alcohol use in adulthood: a replication and extension using a population-based twin sample. Alcohol Clin Exp Res. 2012 Apr; 36(4):693-704. PMID: 21895722; PMCID: PMC3319316; DOI: 10.1111/j.1530-0277.2011.01630.x;

Lee LO, Knight BG. Attentional bias for threat in older adults: moderation of the positivity bias by trait anxiety and stimulus modality. Psychol Aging. 2009 Sep; 24(3):741-7. PMID: 19739931; PMCID: PMC2743240; DOI: 10.1037/a0016409;

Knight BG & Lee LO. In KE Laidlaw & BG Knight (Eds.), The Handbook of Emotional Disorders in Late Life: Assessment and Treatment. Contextual adult lifespan theory for adapting psychotherapy (CALTAP). Oxford University Press. Oxford, UK. 2008.
Knight BG, Lee LO. Encyclopedia of Gerontology. Mental health. Elsevier. Amsterdam, the Netherlands. 2007; 3:159-166.
Thompson-Hollands, J., Lee, L. O., & Schnurr, P. P. (in press). In C. Castro & C. Warner (Eds.), Mental Healthcare for Military and Veteran Personnel. Military PTSD. American Psychiatric Association. Washington, D. C.
MacDonald HZ, Franz MR, Pless Kaiser A, Lee LO, Lawrence AE, Fairbank JA, Vasterling JJ (in press). Associations of warzone Veteran and intimate partner PTSD symptoms with child depression, anxiety, hyperactivity, and conduct problems. Military Behavioral Health.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 45 publications over 15 distinct years, with a maximum of 6 publications in 2014 and 2019 and 2022

Bar chart showing 45 publications over 15 distinct years, with a maximum of 6 publications in 2014 and 2019 and 2022

Year	Publications
2007	1
2008	1
2009	1
2011	1
2012	1
2014	6
2015	3
2016	3
2017	2
2018	3
2019	6
2020	5
2021	1
2022	6
2023	5

Media Mentions
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Study: Optimistic attitude may be secret to living past 85

WHDH 8/27/2019

Want To Live Longer? Be An Optimist, Boston Researchers Say

CBS Boston 8/27/2019

Irritating Positive People to Inherit Earth

Gizmodo 8/27/2019

Cheer up! Being a downer could knock years off your life: study

New York Post 8/27/2019

Optimism Study Gives Optimists More Reason to Be Optimistic

Psychology Today 8/27/2019

Optimists are up to 70% more likely to live to be 85, study finds

Daily Mail 8/26/2019

New Study Finds Surprising Clue to 'Exceptional Longevity' for Men and Women

MSN 8/26/2019

Glass-Half-Full Attitude May Help You Live Past 85, New Study Finds

STAT 8/26/2019

Staying Optimistic Might Lengthen Your Life, Study Shows

HealthDay 8/26/2019

Optimism may hold secret to longer life, study suggests

The Guardian 8/26/2019

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