Yuzuru Sasamoto, MD, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Ophthalmology

MD, Osaka University
PhD, Osaka University

Yuzuru Sasamoto received his MD from Osaka University Medical School in Japan in 2006. After completion of his medical training in ophthalmology, he received a PhD degree from Osaka University Graduate School of Medicine in 2016. During his PhD program, he worked on corneal regeneration using techniques such as direct reprogramming and induced pluripotent stem (iPS) cell differentiation. He is currently an associate geneticist at the Brigham and Women’s Hospital. Yuzuru is currently working on the comprehensive characterization of the ABCB5 positive limbal stem cells using next-generation sequencing approaches.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Yoshinaga Y, Soma T, Azuma S, Maruyama K, Hashikawa Y, Katayama T, Sasamoto Y, Takayanagi H, Hosen N, Shiina T, Ogasawara K, Hayashi R, Nishida K. Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets. Stem Cell Reports. 2022 07 12; 17(7):1714-1729. PMID: 35750044; PMCID: PMC9287743; DOI: 10.1016/j.stemcr.2022.05.018;
  2. Sasamoto Y, Lee CAA, Yoshihara M, Martin G, Ksander BR, Frank MH, Frank NY. High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells. Ocul Surf. 2022 01; 23:197-200. PMID: 34653711; PMCID: PMC8511872; DOI: 10.1016/j.jtos.2021.10.002;
  3. Watanabe S, Hayashi R, Sasamoto Y, Tsujikawa M, Ksander BR, Frank MH, Quantock AJ, Frank NY, Nishida K. Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities. iScience. 2021 Jun 25; 24(6):102688. PMID: 34195566; PMCID: PMC8233200; DOI: 10.1016/j.isci.2021.102688;
  4. Sasamoto Y, Sasamoto N, Tran J, Mishra A, Ksander BR, Frank MH, Frank NY. Investigation of factors associated with ABCB5-positive limbal stem cell isolation yields from human donors. Ocul Surf. 2020 01; 18(1):114-120. PMID: 31655212; PMCID: PMC7840156; DOI: 10.1016/j.jtos.2019.10.009;
  5. Fujimoto S, Hayashi R, Hara S, Sasamoto Y, Harrington J, Tsujikawa M, Nishida K. KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-ß2 suppression. Regen Ther. 2019 Dec; 11:249-257. PMID: 31538102; PMCID: PMC6745437; DOI: 10.1016/j.reth.2019.08.003;
  6. Sasamoto Y, Ksander BR, Frank MH, Frank NY. Repairing the corneal epithelium using limbal stem cells or alternative cell-based therapies. Expert Opin Biol Ther. 2018 05; 18(5):505-513. PMID: 29471701; PMCID: PMC6317528; DOI: 10.1080/14712598.2018.1443442;
  7. Iwama Y, Soma T, Maeda N, Sasamoto Y, Oie Y, Koh S, Nishida K. Factors Limiting the Visual Outcome After Descemet Stripping Automated Endothelial Keratoplasty: Comprehensive Analysis Including the Graft Position and Irregularity. Cornea. 2018 Jan; 37(1):20-27. PMID: 29040117
  8. Gonzalez G, Sasamoto Y, Ksander BR, Frank MH, Frank NY. Limbal stem cells: identity, developmental origin, and therapeutic potential. Wiley Interdiscip Rev Dev Biol. 2018 03; 7(2). PMID: 29105366; PMCID: PMC5814333; DOI: 10.1002/wdev.303;
  9. Yoshihara M, Sasamoto Y, Hayashi R, Ishikawa Y, Tsujikawa M, Hayashizaki Y, Itoh M, Kawaji H, Nishida K. High-resolution promoter map of human limbal epithelial cells cultured with keratinocyte growth factor and rho kinase inhibitor. Sci Rep. 2017 06 06; 7(1):2845. PMID: 28588247
  10. Hayashi R, Ishikawa Y, Katori R, Sasamoto Y, Taniwaki Y, Takayanagi H, Tsujikawa M, Sekiguchi K, Quantock AJ, Nishida K. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nat Protoc. 2017 04; 12(4):683-696. PMID: 28253236
Showing 10 of 36 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 36 publications over 20 distinct years, with a maximum of 5 publications in 2011


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72 E. Concord Street
Boston MA 02118
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