Yang Jin, MD., PhD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, Beijing Medical University
PhD, State University of New Jersey



Critical Care Medicine, chronic respiratory failure, acute lung injury/ARDS


MECHANISTIC INSIGHTS OF INFLAMMATION AND ORGAN FAILURE AFTER TRAUMA OR CRITICAL ILLNESS
04/01/2018 - 03/31/2022 (PI)
NIH/National Institute of General Medical Sciences
1R01GM127596-01

DEVELOPMENT OF THE RNA MOLECULE-ENRICHED, CELL TYPE-SPECIFIC EXOSOMES
12/13/2017 - 11/30/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
4R33AI121644-03

MECHANISTIC INSIGHTS INTO THE SYSTEMIC INFLAMMATION AND ORGAN FAILURE IN SEPSIS
07/01/2015 - 05/31/2019 (PI)
NIH/National Institute of General Medical Sciences
5R01GM111313-05

CROSS TALK BETWEEN CAV-1 AND FLOT1 IN LUNG INJURY
07/01/2015 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
7R01HL102076-06

DEVELOPMENT OF THE RNA MOLECULE-ENRICHED, CELL TYPE-SPECIFIC EXOSOMES
12/01/2015 - 11/30/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121644-02




Yr Title Project-Sub Proj Pubs
2019 Development of the RNA molecule-enriched, cell type-specific exosomes 5R33AI121644-04
2018 Mechanistic insights of inflammation and organ failure after trauma or critical illness 1R01GM127596-01
2018 Development of the RNA molecule-enriched, cell type-specific exosomes 4R33AI121644-03
2017 Development of the RNA molecule-enriched, cell type-specific exosomes 5R21AI121644-02 8
2016 Development of the RNA molecule-enriched, cell type-specific exosomes 1R21AI121644-01 8
2016 Mechanistic insights into the systemic inflammation and organ failure in sepsis 5R01GM111313-04 9
2015 Mechanistic insights into the systemic inflammation and organ failure in sepsis 7R01GM111313-03 9
2015 Cross talk between cav-1 and flot1 in lung injury 5R01HL102076-05 16
2015 Cross talk between cav-1 and flot1 in lung injury 7R01HL102076-06 16
2014 Mechanistic insights into the systemic inflammation and organ failure in sepsis 1R01GM111313-01 9
Showing 10 of 20 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Lee H, Groot M, Pinilla-Vera M, Fredenburgh LE, Jin Y. Identification of miRNA-rich vesicles in bronchoalveolar lavage fluid: Insights into the function and heterogeneity of extracellular vesicles. J Control Release. 2018 Dec 07; 294:43-52. PMID: 30529727.
     
  2. Zhang D, Lee H, Wang X, Rai A, Groot M, Jin Y. Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses. Mol Ther. 2018 Sep 05; 26(9):2119-2130.View Related Profiles. PMID: 30005869.
     
  3. Lee H, Abston E, Zhang D, Rai A, Jin Y. Extracellular Vesicle: An Emerging Mediator of Intercellular Crosstalk in Lung Inflammation and Injury. Front Immunol. 2018; 9:924.View Related Profiles. PMID: 29780385.
     
  4. Zhang D, Lee H, Zhu Z, Minhas JK, Jin Y. Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2017 Jan 01; 312(1):L110-L121.View Related Profiles. PMID: 27881406; DOI: 10.1152/ajplung.00423.2016;.
     
  5. Lee H, Zhang D, Zhu Z, Dela Cruz CS, Jin Y. Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs. Sci Rep. 2016 10 12; 6:35250.View Related Profiles. PMID: 27731391; DOI: 10.1038/srep35250;.
     
  6. Lee H, Zhang D, Minhas J, Jin Y. Extracellular Vesicles Facilitate the Intercellular Communications in the Pathogenesis of Lung Injury. Cell Dev Biol. 2016 Aug; 5(2).View Related Profiles. PMID: 27722038.
     
  7. Cao Y, Zhang D, Moon HG, Lee H, Haspel JA, Hu K, Xie L, Jin Y. MiR-15a/16 Regulates Apoptosis of Lung Epithelial Cells after Oxidative Stress. Mol Med. 2016 Sep; 22:233-243.View Related Profiles. PMID: 27257854; DOI: 10.2119/molmed.2015.00136;.
     
  8. Zhang D, Lee H, Cao Y, Dela Cruz CS, Jin Y. miR-185 mediates lung epithelial cell death after oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 01; 310(7):L700-10.View Related Profiles. PMID: 26747785; PMCID: PMC4824162; DOI: 10.1152/ajplung.00392.2015;.
     
  9. Lee SJ, Zhang M, Hu K, Lin L, Zhang D, Jin Y. CCN1 suppresses pulmonary vascular smooth muscle contraction in response to hypoxia. Pulm Circ. 2015 Dec; 5(4):716-22.View Related Profiles. PMID: 26697179; PMCID: PMC4671746; DOI: 10.1086/683812;.
     
  10. Lin L, Jin Y, Hu K. Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway. J Biol Chem. 2015 Mar 20; 290(12):7910-7. PMID: 25670857; PMCID: PMC4367289; DOI: 10.1074/jbc.M114.599688;.
     
Showing 10 of 34 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 34 publications over 12 distinct years, with a maximum of 5 publications in 2013 and 2014 and 2016

YearPublications
20052
20061
20082
20091
20103
20113
20122
20135
20145
20152
20165
20183
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

COPD
Inflammation
Lung injury
Sepsis
Contact for Mentoring:


72 E. Concord St Housman (R)
Boston MA 02118
Google Map


Jin's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Co-Authors
_
Similar People
_
Same Department