Yang Jin | Profiles RNS

Yang Jin, MD., PhD

Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, Beijing Medical University
PhD, Rutgers University New Brunswick

Critical Care Medicine, chronic respiratory failure, acute lung injury/ARDS

Member
Boston University
Pulmonary Center

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

BU Research
NIH RePORTER Research

Activated Macrophages and Ozone Toxicity
09/15/2022 - 06/30/2025 (Subcontract PI)
Rutgers, The State University of New Jersey NIH NIEHS
5R01ES004738-28

LncRNA regulates lung inflammation
09/01/2019 - 06/30/2025 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL142758-04

Harnessing Inflammatory Macrophages to Prevent Lung Disease Caused by Chronic Ozone Exposure
12/01/2022 - 11/30/2024 (Subcontract PI)
Rutgers, The State University of New Jersey NIH NIEHS
5R01ES033698-03

Mechanistic insights of inflammation and organ failure after trauma or critical illness
04/01/2018 - 03/31/2024 (PI)
NIH/National Institute of General Medical Sciences
3R01GM127596-04S1

Harnessing Inflammatory Macrophages to Prevent Lung Disease Caused by Chronic Ozone Exposure
02/15/2022 - 11/30/2022 (Subcontract PI)
Rutgers, The State University of New Jersey NIH NIEHS
1R01ES033698-01

Development of the RNA molecule-enriched, cell type-specific exosomes
12/13/2017 - 11/30/2022 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R33AI121644-05

Mechanistic Insights into the Systemic Inflammation and Organ Failure in Sepsis
07/01/2015 - 05/31/2021 (PI)
NIH/National Institute of General Medical Sciences
5R01GM111313-05

Lincenc1 regulates the lipopolysaccharide-induced inflammatory response in macrophages
04/15/2018 - 03/31/2020 (Key Person / Mentor)
PI: Duo Zhang, PhD
NIH/National Heart, Lung, and Blood Institute
5K99HL141685-02

Cross Talk Between Cav-1 and Flot1 in Lung Injury
07/01/2015 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
7R01HL102076-06

Development of the RNA molecule-enriched, cell type-specific exosomes
12/01/2015 - 11/30/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121644-02

Title

Yr	Title	Project-Sub Proj	Pubs
2024	Novel Targets in aging-associated sepsis and organ failure	1R21AG087977-01
2022	LncRNA regulates lung inflammation	5R01HL142758-04
2021	LncRNA regulates lung inflammation	5R01HL142758-03	2
2021	Mechanistic insights of inflammation and organ failure after trauma or critical illness	5R01GM127596-04	8
2021	Mechanistic insights of inflammation and organ failure after trauma or critical illness	3R01GM127596-04S1	8
2020	LncRNA regulates lung inflammation	5R01HL142758-02	2
2020	Mechanistic insights of inflammation and organ failure after trauma or critical illness	5R01GM127596-03	8
2020	Development of the RNA molecule-enriched, cell type-specific exosomes	5R33AI121644-05	9
2019	LncRNA regulates lung inflammation	1R01HL142758-01A1	2
2019	Mechanistic insights of inflammation and organ failure after trauma or critical illness	5R01GM127596-02	8

Showing 10 of 32 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Lee H, Hong R, Jin Y. Altered circular RNA expressions in extracellular vesicles from bronchoalveolar lavage fluids in mice after bacterial infections. Front Immunol. 2024; 15:1354676. PMID: 38638425; PMCID: PMC11024224; DOI: 10.3389/fimmu.2024.1354676;

Gong B, Jin Y, Saito TB. Editorial: Insights into the functional role of extracellular vesicles with specific cell types following infection and inflammation. Front Immunol. 2023; 14:1260310. PMID: 37600789; PMCID: PMC10436616; DOI: 10.3389/fimmu.2023.1260310;

Ali G, Zhang M, Chang J, Zhao R, Jin Y, Zhang J, Ji HL. PAI-1 regulates AT2-mediated re-alveolarization and ion permeability. Stem Cell Res Ther. 2023 Jul 27; 14(1):185. PMID: 37501095; PMCID: PMC10375781; DOI: 10.1186/s13287-023-03414-4;

Bei J, Qiu Y, Cockrell D, Chang Q, Husseinzadeh S, Zhou C, Fang X, Bao X, Jin Y, Gaitas A, Khanipov K, Saito TB, Gong B. Identification of common sequence motifs shared exclusively among selectively packed exosomal pathogenic microRNAs during rickettsial infections. J Cell Physiol. 2023 Aug; 238(8):1937-1948. PMID: 37334929; DOI: 10.1002/jcp.31061;

Ali G, Zhang M, Chang J, Zhao R, Jin Y, Ji HL. PAI-1 regulates AT2-mediated re-alveolarization and ion permeability. Res Sq. 2023 Mar 01. PMID: 36909505; PMCID: PMC10002791; DOI: 10.21203/rs.3.rs-2289657/v1;

Ryu S, Ni K, Wang C, Sivanantham A, Carnino JM, Ji HL, Jin Y. Bacterial Outer Membrane Vesicles Promote Lung Inflammatory Responses and Macrophage Activation via Multi-Signaling Pathways. Biomedicines. 2023 Feb 15; 11(2).View Related Profiles.

Sivanantham, Ayyanar
Carnino, Jonathan
Jin, Yang

PMID: 36831104; PMCID: PMC9953134; DOI: 10.3390/biomedicines11020568;

Sivanantham A, Alktaish W, Murugeasan S, Gong B, Lee H, Jin Y. Caveolin-1 regulates OMV-induced macrophage pro-inflammatory activation and multiple Toll-like receptors. Front Immunol. 2023; 14:1044834.View Related Profiles.

Sivanantham, Ayyanar
Alktaish, Ward
Jin, Yang

PMID: 36817491; PMCID: PMC9933776; DOI: 10.3389/fimmu.2023.1044834;

Bei J, Qiu Y, Cockrell D, Chang Q, Husseinzadeh S, Zhou C, Gaitas A, Fang X, Jin Y, Khanipov K, Saito TB, Gong B. Identification of common sequence motifs shared exclusively among selectively packed exosomal pathogenic microRNAs during rickettsial infections. bioRxiv. 2023 Jan 07. PMID: 36712112; PMCID: PMC9881928; DOI: 10.1101/2023.01.06.522907;

Park S, Kim M, Park M, Jin Y, Lee SJ, Lee H. Specific upregulation of extracellular miR-6238 in particulate matter-induced acute lung injury and its immunomodulation. J Hazard Mater. 2023 Mar 05; 445:130466. PMID: 36455323; DOI: 10.1016/j.jhazmat.2022.130466;

Zhou C, Bei J, Qiu Y, Chang Q, Nyong E, Vasilakis N, Yang J, Krishnan B, Khanipov K, Jin Y, Fang X, Gaitas A, Gong B. Exosomally Targeting microRNA23a Ameliorates Microvascular Endothelial Barrier Dysfunction Following Rickettsial Infection. Front Immunol. 2022; 13:904679. PMID: 35812423; PMCID: PMC9260018; DOI: 10.3389/fimmu.2022.904679;

Showing 10 of 87 results. Show More

Sivanantham A, Jin Y. Impact of Storage Conditions on EV Integrity/Surface Markers and Cargos. Life (Basel). 2022 May 07; 12(5).View Related Profiles.

Sivanantham, Ayyanar
Jin, Yang

PMID: 35629364; PMCID: PMC9146501; DOI: 10.3390/life12050697;

Sivanantham A., Lee H., Jin Y. . Extracellular Vesicles in Diagnosis and Therapy. Methods in Molecular Biology, vol 2504. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2341-1_10 Federico M., Ridolfi B. (editors). Direct Detection of Extracellular Vesicle miRNAs Using a Single-Step RT-qPCR Assay. Humana, New York, NY. New York. 2022; vol 2504:137-145. View Publication

Carnino JM, Lee H, Smith LC, Sunil VR, Rancourt RC, Vayas K, Cervelli J, Kwok ZH, Ni K, Laskin JD, Jin Y, Laskin DL. Microvesicle-Derived miRNAs Regulate Proinflammatory Macrophage Activation in the Lung Following Ozone Exposure. Toxicol Sci. 2022 Apr 26; 187(1):162-174.View Related Profiles.

Carnino, Jonathan
Jin, Yang
Kwok, Zhi

PMID: 35201360; PMCID: PMC9041552; DOI: 10.1093/toxsci/kfac025;

Carnino JM, Hao Kwok Z, Jin Y. Extracellular Vesicles: A Novel Opportunity for Precision Medicine in Respiratory Diseases. Front Med (Lausanne). 2021; 8:661679.View Related Profiles.

Carnino, Jonathan
Jin, Yang
Kwok, Zhi

PMID: 34368181; PMCID: PMC8342920; DOI: 10.3389/fmed.2021.661679;

Liu Y, Zhou C, Su Z, Chang Q, Qiu Y, Bei J, Gaitas A, Xiao J, Drelich A, Khanipov K, Jin Y, Golovko G, Saito TB, Gong B. Endothelial Exosome Plays a Functional Role during Rickettsial Infection. mBio. 2021 05 11; 12(3). PMID: 33975935; PMCID: PMC8262936; DOI: 10.1128/mBio.00769-21;

Liu Y, Garron TM, Chang Q, Su Z, Zhou C, Qiu Y, Gong EC, Zheng J, Yin YW, Ksiazek T, Brasel T, Jin Y, Boor P, Comer JE, Gong B. Cell-Type Apoptosis in Lung during SARS-CoV-2 Infection. Pathogens. 2021 Apr 23; 10(5). PMID: 33922476; PMCID: PMC8145065; DOI: 10.3390/pathogens10050509;

Kwok ZH, Ni K, Jin Y. Extracellular Vesicle Associated Non-Coding RNAs in Lung Infections and Injury. Cells. 2021 04 21; 10(5).View Related Profiles.

Jin, Yang
Kwok, Zhi

PMID: 33919158; PMCID: PMC8143102; DOI: 10.3390/cells10050965;

Kwok ZH, Wang C, Jin Y. Extracellular Vesicle Transportation and Uptake by Recipient Cells: A Critical Process to Regulate Human Diseases. Processes (Basel). 2021 Feb; 9(2).View Related Profiles.

Jin, Yang
Kwok, Zhi

PMID: 34336602; PMCID: PMC8323758; DOI: 10.3390/pr9020273;

Lee H, He X, Ni K, Carnino JM, Jin Y. Low concentration of polyethylene glycol facilitates separation of extracellular vesicles from bronchoalveolar lavage fluid. Am J Physiol Lung Cell Mol Physiol. 2021 04 01; 320(4):L522-L529.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 33438468; PMCID: PMC8238157; DOI: 10.1152/ajplung.00318.2020;

Kwok ZH, Wang C, Jin Y. . Extracellular Vesicle Transportation and Uptake by Recipient Cells: A Critical Process to Regulate Human Diseases. Processes. 2021; 2(9):273.

Li L, Liu Y, Chiu C, Jin Y, Zhou W, Peng M, Chen LC, Sun Q, Gao J. A Regulatory Role of Chemokine Receptor CXCR3 in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Emphysema. Inflammation. 2021 Jun; 44(3):985-998. PMID: 33415536; DOI: 10.1007/s10753-020-01393-9;

Carnino JM, Jin Y. Intercellular Communication via Extracellular Vesicle Cargo MicroRNAs: Challenges for Experimental Design. Crit Care Med. 2020 12; 48(12):e1364-e1365.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 33255130

Ni K, Wang C, Carnino JM, Jin Y. The Evolving Role of Caveolin-1: A Critical Regulator of Extracellular Vesicles. Med Sci (Basel). 2020 Nov 04; 8(4).View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 33158117; PMCID: PMC7712126; DOI: 10.3390/medsci8040046;

Carnino JM, Lee H, He X, Groot M, Jin Y. Extracellular vesicle-cargo miR-185-5p reflects type II alveolar cell death after oxidative stress. Cell Death Discov. 2020; 6:82.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 32963810; PMCID: PMC7484781; DOI: 10.1038/s41420-020-00317-8;

Xiao J, Zhang B, Su Z, Liu Y, Shelite TR, Chang Q, Wang P, Bukreyev A, Soong L, Jin Y, Ksiazek T, Gaitas A, Rossi SL, Zhou J, Laposata M, Saito TB, Gong B. EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammation. bioRxiv. 2020 Sep 04. PMID: 32908983; PMCID: PMC7480044; DOI: 10.1101/2020.09.04.282806;

Su Z, Chang Q, Drelich A, Shelite T, Judy B, Liu Y, Xiao J, Zhou C, He X, Jin Y, Saito T, Tang S, Soong L, Wakamiya M, Fang X, Bukreyev A, Ksiazek T, Russell WK, Gong B. Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections. PLoS Negl Trop Dis. 2020 07; 14(7):e0007960. PMID: 32687500; PMCID: PMC7392349; DOI: 10.1371/journal.pntd.0007960;

Carnino JM, Ryu S, Ni K, Jin Y. Pretreated household materials carry similar filtration protection against pathogens when compared with surgical masks. Am J Infect Control. 2020 08; 48(8):883-889.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 32464294; PMCID: PMC7255289; DOI: 10.1016/j.ajic.2020.05.024;

Carnino JM, Ni K, Jin Y. Post-translational Modification Regulates Formation and Cargo-Loading of Extracellular Vesicles. Front Immunol. 2020; 11:948.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 32528471; PMCID: PMC7257894; DOI: 10.3389/fimmu.2020.00948;

Liu Y, Xiao J, Zhang B, Shelite TR, Su Z, Chang Q, Judy B, Li X, Drelich A, Bei J, Zhou Y, Zheng J, Jin Y, Rossi SL, Tang SJ, Wakamiya M, Saito T, Ksiazek T, Kaphalia B, Gong B. Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections. Lab Invest. 2020 08; 100(8):1030-1041. PMID: 32238906; PMCID: PMC7111589; DOI: 10.1038/s41374-020-0420-9;

Lee H, He X, Le T, Carnino JM, Jin Y. Single-step RT-qPCR for detection of extracellular vesicle microRNAs in vivo: a time- and cost-effective method. Am J Physiol Lung Cell Mol Physiol. 2020 04 01; 318(4):L742-L749.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 32073880; PMCID: PMC7191479; DOI: 10.1152/ajplung.00430.2019;

Zhang D, Lee H, Jin Y. Delivery of Functional Small RNAs via Extracellular Vesicles In Vitro and In Vivo. Methods Mol Biol. 2020; 2115:107-117. PMID: 32006397; PMCID: PMC7958886; DOI: 10.1007/978-1-0716-0290-4_6;

Andres J, Smith LC, Murray A, Jin Y, Businaro R, Laskin JD, Laskin DL. Role of extracellular vesicles in cell-cell communication and inflammation following exposure to pulmonary toxicants. Cytokine Growth Factor Rev. 2020 02; 51:12-18. PMID: 31901309; PMCID: PMC7052797; DOI: 10.1016/j.cytogfr.2019.12.001;

Carnino JM, Lee H, Jin Y. Isolation and characterization of extracellular vesicles from Broncho-alveolar lavage fluid: a review and comparison of different methods. Respir Res. 2019 Oct 30; 20(1):240.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 31666080; PMCID: PMC6822481; DOI: 10.1186/s12931-019-1210-z;

Lee H, Carnino JM, Jin Y. Caveolin-1 regulates extracellular vesicle-miRNA packaging. Aging (Albany NY). 2019 10 24; 11(20):8733-8735.View Related Profiles.

Carnino, Jonathan
Jin, Yang

PMID: 31652419; PMCID: PMC6834420; DOI: 10.18632/aging.102370;

Zhang D, Lee H, Wang X, Groot M, Sharma L, Dela Cruz CS, Jin Y. A potential role of microvesicle-containing miR-223/142 in lung inflammation. Thorax. 2019 09; 74(9):865-874.View Related Profiles.

Year	Publications
1996	1
1999	1
2002	1
2005	2
2006	1
2008	2
2009	1
2010	3
2011	3
2012	2
2013	5
2014	8
2015	5
2016	6
2017	4
2018	6
2019	5
2020	10
2021	8
2022	5
2023	7
2024	1