Yang Jin, MD., PhD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, Beijing Medical University
PhD, State University of New Jersey



Critical Care Medicine, chronic respiratory failure, acute lung injury/ARDS


MECHANISTIC INSIGHTS OF INFLAMMATION AND ORGAN FAILURE AFTER TRAUMA OR CRITICAL ILLNESS
04/01/2018 - 03/31/2022 (PI)
NIH/National Institute of General Medical Sciences
1R01GM127596-01

DEVELOPMENT OF THE RNA MOLECULE-ENRICHED, CELL TYPE-SPECIFIC EXOSOMES
12/13/2017 - 11/30/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
4R33AI121644-03

MECHANISTIC INSIGHTS INTO THE SYSTEMIC INFLAMMATION AND ORGAN FAILURE IN SEPSIS
07/01/2015 - 05/31/2019 (PI)
NIH/National Institute of General Medical Sciences
5R01GM111313-05

CROSS TALK BETWEEN CAV-1 AND FLOT1 IN LUNG INJURY
07/01/2015 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
7R01HL102076-06

DEVELOPMENT OF THE RNA MOLECULE-ENRICHED, CELL TYPE-SPECIFIC EXOSOMES
12/01/2015 - 11/30/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121644-02




Yr Title Project-Sub Proj Pubs
2018 Mechanistic insights of inflammation and organ failure after trauma or critical illness 1R01GM127596-01
2018 Development of the RNA molecule-enriched, cell type-specific exosomes 4R33AI121644-03
2017 Development of the RNA molecule-enriched, cell type-specific exosomes 5R21AI121644-02 5
2016 Development of the RNA molecule-enriched, cell type-specific exosomes 1R21AI121644-01 5
2016 Mechanistic insights into the systemic inflammation and organ failure in sepsis 5R01GM111313-04 6
2015 Mechanistic insights into the systemic inflammation and organ failure in sepsis 7R01GM111313-03 6
2015 Cross talk between cav-1 and flot1 in lung injury 5R01HL102076-05 13
2015 Cross talk between cav-1 and flot1 in lung injury 7R01HL102076-06 13
2014 Mechanistic insights into the systemic inflammation and organ failure in sepsis 1R01GM111313-01 6
2014 Cross talk between cav-1 and flot1 in lung injury 5R01HL102076-04 13
Showing 10 of 19 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Zhang D, Lee H, Wang X, Rai A, Groot M, Jin Y. Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses. Mol Ther. 2018 Sep 05; 26(9):2119-2130. PMID: 30005869.
     
  2. Lee H, Abston E, Zhang D, Rai A, Jin Y. Extracellular Vesicle: An Emerging Mediator of Intercellular Crosstalk in Lung Inflammation and Injury. Front Immunol. 2018; 9:924. PMID: 29780385.
     
  3. Zhang D, Lee H, Zhu Z, Minhas JK, Jin Y. Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2017 Jan 01; 312(1):L110-L121. PMID: 27881406; DOI: 10.1152/ajplung.00423.2016;.
     
  4. Lee H, Zhang D, Zhu Z, Dela Cruz CS, Jin Y. Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs. Sci Rep. 2016 10 12; 6:35250. PMID: 27731391; DOI: 10.1038/srep35250;.
     
  5. Lee H, Zhang D, Minhas J, Jin Y. Extracellular Vesicles Facilitate the Intercellular Communications in the Pathogenesis of Lung Injury. Cell Dev Biol. 2016 Aug; 5(2). PMID: 27722038.
     
  6. Cao Y, Zhang D, Moon HG, Lee H, Haspel JA, Hu K, Xie L, Jin Y. MiR-15a/16 Regulates Apoptosis of Lung Epithelial Cells after Oxidative Stress. Mol Med. 2016 Sep; 22:233-243. PMID: 27257854; DOI: 10.2119/molmed.2015.00136;.
     
  7. Zhang D, Lee H, Cao Y, Dela Cruz CS, Jin Y. miR-185 mediates lung epithelial cell death after oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 01; 310(7):L700-10. PMID: 26747785; PMCID: PMC4824162; DOI: 10.1152/ajplung.00392.2015;.
     
  8. Lee SJ, Zhang M, Hu K, Lin L, Zhang D, Jin Y. CCN1 suppresses pulmonary vascular smooth muscle contraction in response to hypoxia. Pulm Circ. 2015 Dec; 5(4):716-22. PMID: 26697179; PMCID: PMC4671746; DOI: 10.1086/683812;.
     
  9. Lin L, Jin Y, Hu K. Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway. J Biol Chem. 2015 Mar 20; 290(12):7910-7. PMID: 25670857; PMCID: PMC4367289; DOI: 10.1074/jbc.M114.599688;.
     
  10. Wang H, Yu B, Deng J, Jin Y, Xie L. Serum miR-122 correlates with short-term mortality in sepsis patients. Crit Care. 2014 Dec 12; 18(6):704. PMID: 25672224; PMCID: PMC4262971; DOI: 10.1186/s13054-014-0704-9;.
     
Showing 10 of 33 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 33 publications over 12 distinct years, with a maximum of 5 publications in 2013 and 2014 and 2016

YearPublications
20052
20061
20082
20091
20103
20113
20122
20135
20145
20152
20165
20182
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

COPD
Inflammation
Lung injury
Sepsis
Contact for Mentoring:


72 E. Concord St Housman (R)
Boston MA 02118
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