Keywords
Last Name

Yang Jin, MD., PhD

TitleAssociate Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionPulmonary, Allergy, Sleep & Critical Care Medicine
Address725 Albany Street, Shapiro Center Suite 9B
Boston MA 02118
Phone(617) 638-7480
 Research Expertise & Professional Interests
Critical Care Medicine, chronic respiratory failure, acute lung injury/ARDS

 Self-Described Keywords
  • Lung injury
  • Sepsis
  • COPD
  • Inflammation
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Zhang D, Lee H, Zhu Z, Minhas JK, Jin Y. Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol. 2017 Jan 01; 312(1):L110-L121. PMID: 27881406.
    View in: PubMed
  2. Lee H, Zhang D, Zhu Z, Dela Cruz CS, Jin Y. Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs. Sci Rep. 2016 Oct 12; 6:35250. PMID: 27731391.
    View in: PubMed
  3. Lee H, Zhang D, Minhas J, Jin Y. Extracellular Vesicles Facilitate the Intercellular Communications in the Pathogenesis of Lung Injury. Cell Dev Biol. 2016 Aug; 5(2). PMID: 27722038.
    View in: PubMed
  4. Cao Y, Zhang D, Moon HG, Lee H, Haspel JA, Hu K, Xie L, Jin Y. MiR-15a/16 Regulates Apoptosis of Lung Epithelial Cells after Oxidative Stress. Mol Med. 2016 Apr 27; 22. PMID: 27257854.
    View in: PubMed
  5. Zhang D, Lee H, Cao Y, Dela Cruz CS, Jin Y. miR-185 mediates lung epithelial cell death after oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1; 310(7):L700-10. PMID: 26747785.
    View in: PubMed
  6. Lee SJ, Zhang M, Hu K, Lin L, Zhang D, Jin Y. CCN1 suppresses pulmonary vascular smooth muscle contraction in response to hypoxia. Pulm Circ. 2015 Dec; 5(4):716-22. PMID: 26697179.
    View in: PubMed
  7. Lin L, Jin Y, Hu K. Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway. J Biol Chem. 2015 Mar 20; 290(12):7910-7. PMID: 25670857.
    View in: PubMed
  8. Wang H, Yu B, Deng J, Jin Y, Xie L. Serum miR-122 correlates with short-term mortality in sepsis patients. Crit Care. 2014 Dec 12; 18(6):704. PMID: 25672224.
    View in: PubMed
  9. Moon HG, Yang J, Zheng Y, Jin Y. miR-15a/16 regulates macrophage phagocytosis after bacterial infection. J Immunol. 2014 Nov 1; 193(9):4558-67. PMID: 25261473.
    View in: PubMed
  10. Lin L, Jin Y, Mars WM, Reeves WB, Hu K. Myeloid-derived tissue-type plasminogen activator promotes macrophage motility through FAK, Rac1, and NF-?B pathways. Am J Pathol. 2014 Oct; 184(10):2757-67. PMID: 25131752.
    View in: PubMed
  11. Moon HG, Kim SH, Gao J, Quan T, Qin Z, Osorio JC, Rosas IO, Wu M, Tesfaigzi Y, Jin Y. CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke. Am J Physiol Lung Cell Mol Physiol. 2014 Aug 15; 307(4):L326-37. PMID: 24973403.
    View in: PubMed
  12. Yang J, Moon HG, Chettimada S, Jin Y. Cross-talk between apoptosis and autophagy in lung epithelial cell death. J Biochem Pharmacol Res. 2014 Jun; 2(2):99-109. PMID: 27747144.
    View in: PubMed
  13. Wei S, Moon HG, Zheng Y, Liang X, An CH, Jin Y. Flotillin-2 modulates fas signaling mediated apoptosis after hyperoxia in lung epithelial cells. PLoS One. 2013; 8(10):e77519. PMID: 24204853.
    View in: PubMed
  14. Li G, Fox J, Liu Z, Liu J, Gao GF, Jin Y, Gao H, Wu M. Lyn mitigates mouse airway remodeling by downregulating the TGF-ß3 isoform in house dust mite models. J Immunol. 2013 Dec 01; 191(11):5359-70. PMID: 24127553.
    View in: PubMed
  15. Zheng Y, Lee S, Liang X, Wei S, Moon HG, Jin Y. Suppression of PTRF alleviates the polymicrobial sepsis induced by cecal ligation and puncture in mice. J Infect Dis. 2013 Dec 1; 208(11):1803-12. PMID: 23908488.
    View in: PubMed
  16. Moon HG, Zheng Y, An CH, Kim YK, Jin Y. CCN1 secretion induced by cigarette smoking extracts augments IL-8 release from bronchial epithelial cells. PLoS One. 2013; 8(7):e68199. PMID: 23874538.
    View in: PubMed
  17. Liang X, Wei SQ, Lee SJ, Fung JK, Zhang M, Tanaka A, Choi AM, Jin Y. p62 sequestosome 1/light chain 3b complex confers cytoprotection on lung epithelial cells after hyperoxia. Am J Respir Cell Mol Biol. 2013 Apr; 48(4):489-96. PMID: 23333919.
    View in: PubMed
  18. Jin Y, Choi AM. Cross talk between autophagy and apoptosis in pulmonary hypertension. Pulm Circ. 2012 Oct; 2(4):407-14. PMID: 23372925.
    View in: PubMed
  19. Jin Y, Tanaka A, Choi AM, Ryter SW. Autophagic proteins: new facets of the oxygen paradox. Autophagy. 2012 Mar; 8(3):426-8. PMID: 22302001.
    View in: PubMed
  20. Tanaka A, Jin Y, Lee SJ, Zhang M, Kim HP, Stolz DB, Ryter SW, Choi AM. Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death. Am J Respir Cell Mol Biol. 2012 Apr; 46(4):507-14. PMID: 22095627.
    View in: PubMed
  21. Lee SJ, Kim HP, Jin Y, Choi AM, Ryter SW. Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy. 2011 Aug; 7(8):829-39. PMID: 21685724.
    View in: PubMed
  22. Zhang M, Lee SJ, An C, Xu JF, Joshi B, Nabi IR, Choi AM, Jin Y. Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis. Free Radic Biol Med. 2011 May 15; 50(10):1252-62. PMID: 21382479.
    View in: PubMed
  23. Jin Y, Lee SJ, Minshall RD, Choi AM. Caveolin-1: a critical regulator of lung injury. Am J Physiol Lung Cell Mol Physiol. 2011 Feb; 300(2):L151-60. PMID: 21097526.
    View in: PubMed
  24. Chen ZH, Lam HC, Jin Y, Kim HP, Cao J, Lee SJ, Ifedigbo E, Parameswaran H, Ryter SW, Choi AM. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18880-5. PMID: 20956295.
    View in: PubMed
  25. Lee SJ, Smith A, Guo L, Alastalo TP, Li M, Sawada H, Liu X, Chen ZH, Ifedigbo E, Jin Y, Feghali-Bostwick C, Ryter SW, Kim HP, Rabinovitch M, Choi AM. Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med. 2011 Mar 01; 183(5):649-58. PMID: 20889906.
    View in: PubMed
  26. Zhang M, Lin L, Lee SJ, Mo L, Cao J, Ifedigbo E, Jin Y. Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways. Am J Physiol Lung Cell Mol Physiol. 2009 Nov; 297(5):L945-53. PMID: 19767411.
    View in: PubMed
  27. Jin Y, Kim HP, Cao J, Zhang M, Ifedigbo E, Choi AM. Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death. FASEB J. 2009 Feb; 23(2):341-50. PMID: 18801924.
    View in: PubMed
  28. Jin Y, Kim HP, Chi M, Ifedigbo E, Ryter SW, Choi AM. Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1. Am J Respir Cell Mol Biol. 2008 Aug; 39(2):171-9. PMID: 18323531.
    View in: PubMed
  29. Suh GY, Jin Y, Yi AK, Wang XM, Choi AM. CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2. Am J Respir Cell Mol Biol. 2006 Aug; 35(2):220-6. PMID: 16543610.
    View in: PubMed
  30. Jin Y, Kim HP, Ifedigbo E, Lau LF, Choi AM. Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells. Am J Respir Cell Mol Biol. 2005 Sep; 33(3):297-302. PMID: 15961723.
    View in: PubMed
  31. Jin Y, Choi AM. Cytoprotection of heme oxygenase-1/carbon monoxide in lung injury. Proc Am Thorac Soc. 2005; 2(3):232-5. PMID: 16222043.
    View in: PubMed
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