Sachiko Homma, PhD
Research Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Neurology

PhD, Otsuma Women's University
BS, University of Tsukuba
Websites
favorite icon LinkedIn




Sachiko Homma Takayama, PhD, is a Research Assistant Professor of Neurology at the Chobanian and Avedisian School of Medicine. For her research, she has received funding from many organizations including Friends of FSH Research for researching the roles of molecular chaperones and the ubiquitin-proteasome system in skeletal muscle diseases. She has made new discoveries in the medical field including having identified a new pathway of myogenic cell death in myofibrillar myopathy.


Pathogenesis of myalgia and fatigue after SARS-CoV-2 infection
09/23/2022 - 08/31/2024 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R21AR081655-02

Mechanisms of DUX4-induced muscle atrophy
09/01/2019 - 02/09/2022 (PI)
FSH Society


Mechanisms of DUX4-induced muscle atrophy
05/01/2018 - 10/31/2019 (PI)
Friends of FSH Research


Inhibited protein turnover and TDP-43 aggregation in FSHD pathogenesis
08/01/2015 - 02/28/2019 (PI)
FSH Society




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Homma ST, Wang X, Frere JJ, Gower AC, Zhou J, Lim JK, tenOever BR, Zhou L. Respiratory SARS-CoV-2 Infection Causes Skeletal Muscle Atrophy and Long-Lasting Energy Metabolism Suppression. Biomedicines. 2024 Jun 28; 12(7).View Related Profiles. PMID: 39062017; PMCID: PMC11275164; DOI: 10.3390/biomedicines12071443;
     
  2. Wang X, Chen J, Homma ST, Wang Y, Smith GR, Ruf-Zamojski F, Sealfon SC, Zhou L. Diverse effector and regulatory functions of fibro/adipogenic progenitors during skeletal muscle fibrosis in muscular dystrophy. iScience. 2023 Jan 20; 26(1):105775.View Related Profiles. PMID: 36594034; PMCID: PMC9804115; DOI: 10.1016/j.isci.2022.105775;
     
  3. Beermann ML, Homma S, Miller JB. Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: a pilot study. BMC Res Notes. 2022 May 10; 15(1):163.View Related Profiles. PMID: 35538497; PMCID: PMC9092897; DOI: 10.1186/s13104-022-06054-8;
     
  4. Masteika IF, Sathya A, Homma S, Miller BM, Boyce FM, Miller JB. Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, ?H2AX accumulation, and Bax/Bak-dependence. Biol Open. 2022 02 15; 11(2).View Related Profiles. PMID: 35191484; PMCID: PMC8890089; DOI: 10.1242/bio.059145;
     
  5. Mitsuhashi H, Homma S, Beermann ML, Ishimaru S, Takeda H, Yu BK, Liu K, Duraiswamy S, Boyce FM, Miller JB. Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers. Sci Rep. 2019 02 19; 9(1):2274.View Related Profiles. PMID: 30783185; PMCID: PMC6381186; DOI: 10.1038/s41598-018-36684-7;
     
  6. Mitsuhashi H, Ishimaru S, Homma S, Yu B, Honma Y, Beermann ML, Miller JB. Functional domains of the FSHD-associated DUX4 protein. Biol Open. 2018 Apr 26; 7(4).View Related Profiles. PMID: 29618456; PMCID: PMC5936065; DOI: 10.1242/bio.033977;
     
  7. Homma S, Beermann ML, Yu B, Boyce FM, Miller JB. Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4. Skelet Muscle. 2016 Dec 01; 6(1):42.View Related Profiles. PMID: 27906075; PMCID: PMC5134237; DOI: 10.1186/s13395-016-0113-7;
     
  8. Jones TI, King OD, Himeda CL, Homma S, Chen JC, Beermann ML, Yan C, Emerson CP, Miller JB, Wagner KR, Jones PL. Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy. Clin Epigenetics. 2015; 7(1):37.View Related Profiles. PMID: 25904990; PMCID: PMC4405830; DOI: 10.1186/s13148-015-0072-6;
     
  9. Homma S, Beermann ML, Boyce FM, Miller JB. Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregation. Ann Clin Transl Neurol. 2015 Feb; 2(2):151-66.View Related Profiles. PMID: 25750920; PMCID: PMC4338956; DOI: 10.1002/acn3.158;
     
  10. Himeda CL, Debarnot C, Homma S, Beermann ML, Miller JB, Jones PL, Jones TI. Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene. Mol Cell Biol. 2014 Jun; 34(11):1942-55.View Related Profiles. PMID: 24636994; PMCID: PMC4019064; DOI: 10.1128/MCB.00149-14;
     
Showing 10 of 35 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 35 publications over 24 distinct years, with a maximum of 4 publications in 1997

YearPublications
19921
19931
19951
19962
19974
19981
20001
20013
20021
20031
20041
20061
20072
20091
20101
20112
20121
20141
20152
20161
20181
20191
20223
20241

Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Google Map


Homma's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Co-Authors
_
Similar People
_
Same Department