Nocif Espat | Profiles RNS

Nocif J. Espat, MD

Assistant Dean

Boston University Chobanian & Avedisian School of Medicine

MD, University of Florida College of Medicine
MS, University of Illinois
BA, University of South Florida

Websites

Dr. Espat graduated from the University of Florida College of Medicine in 1990. Dr. Espat works in Providence, RI and specializes in Hematology/Oncology. Dr. Espat is affiliated with Roger Williams Medical Center.

Professor
Boston University Chobanian & Avedisian School of Medicine
Surgery

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Winkler CS, Hardaway JC, Ceyhan ME, Espat NJ, Saied Calvino A. Decreasing colorectal cancer screening disparities: A culturally tailored patient navigation program for Hispanic patients. Cancer. 2022 May 01; 128(9):1820-1825. PMID: 35128638

Jeyarajah DR, Doyle MBM, Espat NJ, Hansen PD, Iannitti DA, Kim J, Thambi-Pillai T, Visser BC. Role of yttrium-90 selective internal radiation therapy in the treatment of liver-dominant metastatic colorectal cancer: an evidence-based expert consensus algorithm. J Gastrointest Oncol. 2020 Apr; 11(2):443-460. PMID: 32399284; PMCID: PMC7212103; DOI: 10.21037/jgo.2020.01.09;

Patel A, Espat NJ, Somasundar P. Fibrolamellar Carcinoma: Novel Insights into a Rare Subtype. Ann Surg Oncol. 2020 Jun; 27(6):1733-1734.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 32056041

Katz SC, Hardaway J, Prince E, Guha P, Cunetta M, Moody A, Wang LJ, Armenio V, Espat NJ, Junghans RP. HITM-SIR: phase Ib trial of intraarterial chimeric antigen receptor T-cell therapy and selective internal radiation therapy for CEA+ liver metastases. Cancer Gene Ther. 2020 05; 27(5):341-355.View Related Profiles.

Espat, Nocif
Guha, Prajna
Katz, Steven
Armenio, Vincent

PMID: 31155611

Raut CP, Espat NJ, Maki RG, Araujo DM, Trent J, Williams TF, Purkayastha DD, DeMatteo RP. Efficacy and Tolerability of 5-Year Adjuvant Imatinib Treatment for Patients With Resected Intermediate- or High-Risk Primary Gastrointestinal Stromal Tumor: The PERSIST-5 Clinical Trial. JAMA Oncol. 2018 12 01; 4(12):e184060. PMID: 30383140; PMCID: PMC6440723; DOI: 10.1001/jamaoncol.2018.4060;

Guha P, Gardell J, Darpolor J, Cunetta M, Lima M, Miller G, Espat NJ, Junghans RP, Katz SC. STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells. Oncogene. 2019 01; 38(4):533-548.View Related Profiles.

Espat, Nocif
Guha, Prajna
Katz, Steven

PMID: 30158673

Ahmad A, Reha J, Saied A, Espat NJ, Somasundar P, Katz SC. Association of primary tumor lymph node ratio with burden of liver metastases and survival in stage IV colorectal cancer. Hepatobiliary Surg Nutr. 2017 Jun; 6(3):154-161.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven

PMID: 28652998; PMCID: PMC5474451; DOI: 10.21037/hbsn.2016.08.08;

Guha P, Cunetta M, Somasundar P, Espat NJ, Junghans RP, Katz SC. Frontline Science: Functionally impaired geriatric CAR-T cells rescued by increased a5ß1 integrin expression. J Leukoc Biol. 2017 08; 102(2):201-208.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Guha, Prajna
Katz, Steven

PMID: 28546503; PMCID: PMC6608072; DOI: 10.1189/jlb.5HI0716-322RR;

Ahmad A, Reha J, Somasundar P, Espat NJ, Katz SC. Predictors of surgical non-referral for colorectal liver metastases. J Surg Res. 2016 09; 205(1):198-203.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven

PMID: 27621019

Thorn M, Guha P, Cunetta M, Espat NJ, Miller G, Junghans RP, Katz SC. Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases. Cancer Gene Ther. 2016 06; 23(6):188-98.View Related Profiles.

Espat, Nocif
Katz, Steven

PMID: 27199222

Showing 10 of 115 results. Show More

Katz SC, Point GR, Cunetta M, Thorn M, Guha P, Espat NJ, Boutros C, Hanna N, Junghans RP. Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery. Cancer Gene Ther. 2016 05; 23(5):142-8.View Related Profiles.

Espat, Nocif
Katz, Steven

PMID: 27080226; PMCID: PMC5153580; DOI: 10.1038/cgt.2016.14;

Katz SC, Burga RA, McCormack E, Wang LJ, Mooring W, Point GR, Khare PD, Thorn M, Ma Q, Stainken BF, Assanah EO, Davies R, Espat NJ, Junghans RP. Phase I Hepatic Immunotherapy for Metastases Study of Intra-Arterial Chimeric Antigen Receptor-Modified T-cell Therapy for CEA+ Liver Metastases. Clin Cancer Res. 2015 Jul 15; 21(14):3149-59.View Related Profiles.

Stainken, Brian
Espat, Nocif
Katz, Steven

PMID: 25850950; PMCID: PMC4506253; DOI: 10.1158/1078-0432.CCR-14-1421;

Saied A, Licata L, Burga RA, Thorn M, McCormack E, Stainken BF, Assanah EO, Khare PD, Davies R, Espat NJ, Junghans RP, Katz SC. Neutrophil:lymphocyte ratios and serum cytokine changes after hepatic artery chimeric antigen receptor-modified T-cell infusions for liver metastases. Cancer Gene Ther. 2014 Nov; 21(11):457-62.View Related Profiles.

Stainken, Brian
Espat, Nocif
Katz, Steven

PMID: 25277132; PMCID: PMC4245365; DOI: 10.1038/cgt.2014.50;

Licata LA, Nguyen CT, Burga RA, Falanga V, Espat NJ, Ayala A, Thorn M, Junghans RP, Katz SC. Biliary obstruction results in PD-1-dependent liver T cell dysfunction and acute inflammation mediated by Th17 cells and neutrophils. J Leukoc Biol. 2013 Oct; 94(4):813-23.View Related Profiles.

Espat, Nocif
Katz, Steven
Falanga, Vincent

PMID: 23883516; PMCID: PMC3774842; DOI: 10.1189/jlb.0313137;

Turaga K, Levine E, Barone R, Sticca R, Petrelli N, Lambert L, Nash G, Morse M, Adbel-Misih R, Alexander HR, Attiyeh F, Bartlett D, Bastidas A, Blazer T, Chu Q, Chung K, Dominguez-Parra L, Espat NJ, Foster J, Fournier K, Garcia R, Goodman M, Hanna N, Harrison L, Hoefer R, Holtzman M, Kane J, Labow D, Li B, Lowy A, Mansfield P, Ong E, Pameijer C, Pingpank J, Quinones M, Royal R, Salti G, Sardi A, Shen P, Skitzki J, Spellman J, Stewart J, Esquivel J. Consensus guidelines from The American Society of Peritoneal Surface Malignancies on standardizing the delivery of hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal cancer patients in the United States. Ann Surg Oncol. 2014 May; 21(5):1501-5. PMID: 23793364; DOI: 10.1245/s10434-013-3061-z;

Saied A, Katz SC, Espat NJ. Regional hepatic therapies: an important component in the management of colorectal cancer liver metastases. Hepatobiliary Surg Nutr. 2013 Apr; 2(2):97-107.View Related Profiles.

Espat, Nocif
Katz, Steven

PMID: 24570923; PMCID: PMC3924659; DOI: 10.3978/j.issn.2304-3881.2012.12.07;

Katz SC, Burga RA, Naheed S, Licata LA, Thorn M, Osgood D, Nguyen CT, Espat NJ, Fletcher JA, Junghans RP. Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor. J Transl Med. 2013 Feb 21; 11:46.View Related Profiles.

Espat, Nocif
Katz, Steven

PMID: 23433424; PMCID: PMC3599052; DOI: 10.1186/1479-5876-11-46;

Oyasiji T, Baldwin K, Katz SC, Espat NJ, Somasundar P. Feasibility of purely laparoscopic resection of locally advanced rectal cancer in obese patients. World J Surg Oncol. 2012 Jul 16; 10:147.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven

PMID: 22799628; PMCID: PMC3411465; DOI: 10.1186/1477-7819-10-147;

Kurniali PC, O'Gara K, Wang X, Wang LJ, Somasundar P, Falanga V, Espat NJ, Katz SC. The effects of sorafenib on liver regeneration in a model of partial hepatectomy. J Surg Res. 2012 Nov; 178(1):242-7.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven
Falanga, Vincent

PMID: 22482755; PMCID: PMC3419806; DOI: 10.1016/j.jss.2012.01.033;

Munireddy S, Katz S, Somasundar P, Espat NJ. Thermal tumor ablation therapy for colorectal cancer hepatic metastasis. J Gastrointest Oncol. 2012 Mar; 3(1):69-77.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven

PMID: 22811871; PMCID: PMC3397642; DOI: 10.3978/j.issn.2078-6891.2012.008;

Boutros C, Ryan K, Katz S, Espat NJ, Somasundar P. Total laparoscopic distal pancreatectomy: beyond selected patients. Am Surg. 2011 Nov; 77(11):1526-30.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 22196669

Baldwin KM, Katz SC, Espat NJ, Somasundar P. Laparoscopic spleen-preserving distal pancreatectomy in elderly subjects: splenic vessel sacrifice may be associated with a higher rate of splenic infarction. HPB (Oxford). 2011 Sep; 13(9):621-5.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven

PMID: 21843262; PMCID: PMC3183446; DOI: 10.1111/j.1477-2574.2011.00341.x;

Katz SC, Ryan K, Ahmed N, Plitas G, Chaudhry UI, Kingham TP, Naheed S, Nguyen C, Somasundar P, Espat NJ, Junghans RP, Dematteo RP. Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis. J Immunol. 2011 Aug 01; 187(3):1150-6.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Katz, Steven

PMID: 21697460; PMCID: PMC3372324; DOI: 10.4049/jimmunol.1004077;

Boutros C, Espat NJ. What, how, and when to offer nonresectional therapy for colorectal cancer liver metastases. J Gastrointest Surg. 2011 Mar; 15(3):420-2. PMID: 21264686; DOI: 10.1007/s11605-011-1428-7;

Katz SC, Donkor C, Glasgow K, Pillarisetty VG, Gönen M, Espat NJ, Klimstra DS, D'Angelica MI, Allen PJ, Jarnagin W, Dematteo RP, Brennan MF, Tang LH. T cell infiltrate and outcome following resection of intermediate-grade primary neuroendocrine tumours and liver metastases. HPB (Oxford). 2010 Dec; 12(10):674-83.View Related Profiles.

Espat, Nocif
Katz, Steven

PMID: 21083792; PMCID: PMC3003477; DOI: 10.1111/j.1477-2574.2010.00231.x;

Boutros C, Somasundar P, Espat NJ. Early results on the use of biomaterials as adjuvant to abdominal wall closure following cytoreduction and hyperthermic intraperitoneal chemotherapy. World J Surg Oncol. 2010 Aug 20; 8:72. PMID: 20727181; PMCID: PMC2931502; DOI: 10.1186/1477-7819-8-72;

Boutros C, Somasundar P, Espat NJ. Open cystogastrostomy, retroperitoneal drainage, and G-J enteral tube for complex pancreatitis-associated pseudocyst: 19 patients with no recurrence. J Gastrointest Surg. 2010 Aug; 14(8):1298-303. PMID: 20535579; DOI: 10.1007/s11605-010-1242-7;

Boutros C, Katz SC, Espat NJ. Management of an incidental liver mass. Surg Clin North Am. 2010 Aug; 90(4):699-718.View Related Profiles.

Espat, Nocif
Katz, Steven

PMID: 20637942

Boutros C, Somasundar P, Razzak A, Helton S, Espat NJ. Omega-3 fatty acids: investigations from cytokine regulation to pancreatic cancer gene suppression. Arch Surg. 2010 Jun; 145(6):515-20.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 20566969

Boutros C, Espat NJ, Somasundar P. Completely laparoscopic subtotal pancreatectomy with splenic artery preservation. J Gastrointest Surg. 2010 Jan; 14(1):171-4.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 19727972

Boutros C, Espat NJ. Further uses of gastrografin in adhesive small bowel obstruction: are we close to a definitive answer. J Surg Res. 2010 May 01; 160(1):60-2. PMID: 19765734; DOI: 10.1016/j.jss.2009.05.036;

Boutros C, Somasundar P, Espat NJ. Extrahepatic cholangiocarcinoma: current surgical strategy. Surg Oncol Clin N Am. 2009 Apr; 18(2):269-88, viii.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 19306812

Boutros C, Somasundar P, Garrean S, Saied A, Espat NJ. Microwave coagulation therapy for hepatic tumors: review of the literature and critical analysis. Surg Oncol. 2010 Mar; 19(1):e22-32.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 19268571

Yi B, Somasundar P, Espat NJ. Novel laparoscopic bipolar radiofrequency energy technology for expedited hepatic tumour ablation. HPB (Oxford). 2009 Mar; 11(2):135-9.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 19590637; PMCID: PMC2697874; DOI: 10.1111/j.1477-2574.2008.00024.x;

Somasundar P, Boutros C, Helton WS, Espat NJ. Evaluation of a bipolar radiofrequency device for laparoscopic hepatic resection: technique and clinical experience in 18 patients. HPB (Oxford). 2009 Mar; 11(2):145-9.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 19590639; PMCID: PMC2697884; DOI: 10.1111/j.1477-2574.2009.00026.x;

Boutros C, Somasundar P, Espat NJ. Low common bile duct bifurcation incidentally discovered during pancreaticoduodenectomy. J Gastrointest Surg. 2009 Nov; 13(11):2092-3.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai

PMID: 19184611

Reyes G, Panchana G, Marengo C, Nieto I, Caputi R, Ribadeneira F, Fuentes A, Espat NJ. An unusual cause of life-threatening rectal bleeding. Am Surg. 2008 Dec; 74(12):1224-6. PMID: 19097546

Garrean S, Hering J, Saied A, Hoopes PJ, Helton WS, Ryan TP, Espat NJ. Ultrasound monitoring of a novel microwave ablation (MWA) device in porcine liver: lessons learned and phenomena observed on ablative effects near major intrahepatic vessels. J Gastrointest Surg. 2009 Feb; 13(2):334-40. PMID: 18937016

Garrean S, Hering J, Saied A, Helton WS, Espat NJ. Radiofrequency ablation of primary and metastatic liver tumors: a critical review of the literature. Am J Surg. 2008 Apr; 195(4):508-20. PMID: 18361927; DOI: 10.1016/j.amjsurg.2007.06.024;

Cai J, Razzak A, Hering J, Saed A, Babcock TA, Helton S, Espat NJ. Feasibility evaluation of emodin (rhubarb extract) as an inhibitor of pancreatic cancer cell proliferation in vitro. JPEN J Parenter Enteral Nutr. 2008 Mar-Apr; 32(2):190-6. PMID: 18407913

Aldridge C, Razzak A, Babcock TA, Helton WS, Espat NJ. Lipopolysaccharide-stimulated RAW 264.7 macrophage inducible nitric oxide synthase and nitric oxide production is decreased by an omega-3 fatty acid lipid emulsion. J Surg Res. 2008 Oct; 149(2):296-302. PMID: 18262557; PMCID: PMC2596918; DOI: 10.1016/j.jss.2007.12.758;

Galvani CA, Gorodner MV, Moser F, Jacobsen G, Chretien C, Espat NJ, Donahue P, Horgan S. Robotically assisted laparoscopic transhiatal esophagectomy. Surg Endosc. 2008 Jan; 22(1):188-95. PMID: 17939004; DOI: 10.1007/s00464-007-9441-3;

Garrean S, Hering J, Saied A, Jani J, Espat NJ. Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome. Am Surg. 2008 Jan; 74(1):79-83. PMID: 18274437

Cai J, Wang Y, Xuan Z, Hering J, Helton S, Espat NJ. The abdominal cocoon: a rare cause of intestinal obstruction in two patients. Am Surg. 2007 Nov; 73(11):1133-5. PMID: 18092648

Hering J, Garrean S, Dekoj TR, Razzak A, Saied A, Trevino J, Babcock TA, Espat NJ. Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells. Ann Surg Oncol. 2007 Dec; 14(12):3620-8. PMID: 17896154

Razzak A, Aldrich C, Babcock TA, Saied A, Espat NJ. Attenuation of iNOS in an LPS-stimulated macrophage model by omega-3 fatty acids is independent of COX-2 derived PGE2. J Surg Res. 2008 Apr; 145(2):244-50. PMID: 18067925

Garrean S, Hering J, Helton WS, Espat NJ. A primer on transarterial, chemical, and thermal ablative therapies for hepatic tumors. Am J Surg. 2007 Jul; 194(1):79-88. PMID: 17560915; DOI: 10.1016/j.amjsurg.2006.11.025;

Garrean S, Muhs A, Bui JT, Blend MJ, Owens C, Helton WS, Espat NJ. Complete eradication of hepatic metastasis from colorectal cancer by Yttrium-90 SIRT. World J Gastroenterol. 2007 Jun 07; 13(21):3016-9. PMID: 17589957; PMCID: PMC4171159; DOI: 10.3748/wjg.v13.i21.3016;

Jho DH, Jho DJ, Chejfec G, Ahn M, Ong ES, Espat NJ. Primary biliary B-cell lymphoma of the cystic duct causing obstructive jaundice. Am Surg. 2007 May; 73(5):508-10. PMID: 17521008

Poirier M, Espat NJ. Scoring systems: predictive accuracy through specificity. Lancet Oncol. 2007 Apr; 8(4):282-3. PMID: 17395101

Dekoj T, Lee S, Desai S, Trevino J, Babcock TA, Helton WS, Espat NJ. G2/M cell-cycle arrest and apoptosis by n-3 fatty acids in a pancreatic cancer model. J Surg Res. 2007 May 01; 139(1):106-12. PMID: 17291531; DOI: 10.1016/j.jss.2006.10.024;

Hering J, Garrean S, Saied A, Helton WS, Espat NJ. Use of radiofrequency hepatic parenchymal transection device in hepatic hemangioma resection: early experience and lessons learned. HPB (Oxford). 2007; 9(4):319-23. PMID: 18345312; PMCID: PMC2215404; DOI: 10.1080/13651820701457984;

Gabram SG, Espat NJ, Jacobs LM, Macleod JB, Rozycki GS. Academic careers in surgery: the many paths from which to choose. J Surg Educ. 2007 Jan-Feb; 64(1):27-35. PMID: 17320803; DOI: 10.1016/j.cursur.2006.08.011;

Trevino JG, Espat NJ, Helton WS. Intraductal papillary mucinous neoplasms of the pancreas. Curr Treat Options Gastroenterol. 2006 Sep; 9(5):385-90. PMID: 16942663

Sharif S, Broman M, Babcock T, Ong E, Jho D, Rudnicki M, Helton WS, Espat NJ. A priori dietary omega-3 lipid supplementation results in local pancreatic macrophage and pulmonary inflammatory response attenuation in a model of experimental acute edematous pancreatitis (AEP). JPEN J Parenter Enteral Nutr. 2006 Jul-Aug; 30(4):271-6. PMID: 16804123

Feng AY, Espat NJ, Sharif S, Glew J, Sullivan C, Kaczor T, Block KI. Integrative Tumor Board: cholangicocarcinoma. Integr Cancer Ther. 2006 Jun; 5(2):131-49. PMID: 16770862

Ong ES, Helton WS, Jho D, Espat NJ. SURGISIS-assisted surgical site control in the delayed repair of a complex bile duct injury after laparoscopic cholecystectomy. J Gastrointest Surg. 2006 Feb; 10(2):202-6. PMID: 16455451; DOI: 10.1016/j.gassur.2005.07.004;

Espat NJ. Reported outcome factors for hepatic metastasectomy. J Gastrointest Surg. 2006 Feb; 10(2):155-160. PMID: 16622977

Ong ES, Poirier M, Espat NJ. Hepatic intra-arterial chemotherapy. Ann Surg Oncol. 2006 Feb; 13(2):142-9. PMID: 16418886; DOI: 10.1245/ASO.2006.01.005;

Alseidi A, Helton WS, Espat NJ. Does the literature support an indication for hepatic metastasectomy other than for colorectal primary? J Gastrointest Surg. 2006 Jan; 10(1):99-104. PMID: 16368498; DOI: 10.1016/j.gassur.2005.04.009;

Zgodzinski W, Dekoj T, Espat NJ. Understanding clinical issues in postoperative nutrition after pancreaticoduodenectomy. Nutr Clin Pract. 2005 Dec; 20(6):654-61. PMID: 16306303

Zgodzinski W, Espat NJ. Radiofrequency ablation for incidentally identified primary intrahepatic cholangiocarcinoma. World J Gastroenterol. 2005 Sep 07; 11(33):5239-40. PMID: 16127762; PMCID: PMC4320405; DOI: 10.3748/wjg.v11.i33.5239;

Helton WS, Fisichella PM, Berger R, Horgan S, Espat NJ, Abcarian H. Short-term outcomes with small intestinal submucosa for ventral abdominal hernia. Arch Surg. 2005 Jun; 140(6):549-60; discussion 560-2.View Related Profiles.

Espat, Nocif
Fisichella, Piero

PMID: 15967902

Babcock TA, Dekoj T, Espat NJ. Experimental studies defining omega-3 fatty acid antiinflammatory mechanisms and abrogation of tumor-related syndromes. Nutr Clin Pract. 2005 Feb; 20(1):62-74. PMID: 16207647

Espat NJ, Jacobsen G, Horgan S, Donahue P. Minimally invasive treatment of esophageal cancer: laparoscopic staging to robotic esophagectomy. Cancer J. 2005 Jan-Feb; 11(1):10-7. PMID: 15831219

Jho DH, Engelhard HH, Gandhi R, Chao J, Babcock T, Ong E, Espat NJ. Ciliary neurotrophic factor upregulates ubiquitin-proteasome components in a rat model of neuronal injury. Cytokine. 2004 Sep 21; 27(6):142-51. PMID: 15304243; DOI: 10.1016/j.cyto.2004.05.003;

Breen HB, Espat NJ. The ubiquitin-proteasome proteolysis pathway: potential target for disease intervention. JPEN J Parenter Enteral Nutr. 2004 Jul-Aug; 28(4):272-7. PMID: 15291411

Babcock TA, Helton WS, Anwar KN, Zhao YY, Espat NJ. Synergistic anti-inflammatory activity of omega-3 lipid and rofecoxib pretreatment on macrophage proinflammatory cytokine production occurs via divergent NF-kappaB activation. JPEN J Parenter Enteral Nutr. 2004 Jul-Aug; 28(4):232-9; discussion 239-40. PMID: 15291404; DOI: 10.1177/0148607104028004232;

Jho DH, Cole SM, Lee EM, Espat NJ. Role of omega-3 fatty acid supplementation in inflammation and malignancy. Integr Cancer Ther. 2004 Jun; 3(2):98-111. PMID: 15165497; DOI: 10.1177/1534735404264736;

Espat NJ, Ong ES, Helton WS, Nyhus LM. 1990-2001 US general surgery chief resident gastric surgery operative experience: analysis of paradigm shift. J Gastrointest Surg. 2004 May-Jun; 8(4):471-8. PMID: 15120373; DOI: 10.1016/j.gassur.2004.02.002;

Elli E, Espat NJ, Berger R, Jacobsen G, Knoblock L, Horgan S. Robotic-assisted thoracoscopic resection of esophageal leiomyoma. Surg Endosc. 2004 Apr; 18(4):713-6. PMID: 15026895; DOI: 10.1007/s00464-003-8829-y;

Espat NJ. A potential role for perioperative hepatic arterial infusion chemotherapy? Cancer. 2004 Feb 01; 100(3):437-40. PMID: 14745858; DOI: 10.1002/cncr.11941;

Jho DH, Engelhard HH, Juarez A, Espat NJ. Simplified surgical placement and stabilization methods for intracerebroventricular cannulas in rat lateral ventricles. Lab Anim (NY). 2003 Oct; 32(9):43-8. PMID: 15235663; DOI: 10.1038/laban1003-43;

Nathanson DR, Espat NJ, Nash GM, D'Alessio M, Thaler H, Minsky BD, Enker W, Wong D, Guillem J, Cohen A, Paty PB. Evaluation of preoperative and postoperative radiotherapy on long-term functional results of straight coloanal anastomosis. Dis Colon Rectum. 2003 Jul; 46(7):888-94. PMID: 12847361

Horgan S, Berger RA, Elli EF, Espat NJ. Robotic-assisted minimally invasive transhiatal esophagectomy. Am Surg. 2003 Jul; 69(7):624-6. PMID: 12889629

Sturgeon C, Chejfec G, Espat NJ. Gastrointestinal stromal tumors: a spectrum of disease. Surg Oncol. 2003 Jul; 12(1):21-6. PMID: 12689667

Babcock TA, Kurland A, Helton WS, Rahman A, Anwar KN, Espat NJ. Inhibition of activator protein-1 transcription factor activation by omega-3 fatty acid modulation of mitogen-activated protein kinase signaling kinases. JPEN J Parenter Enteral Nutr. 2003 May-Jun; 27(3):176-80; discussion 181. PMID: 12757110; DOI: 10.1177/0148607103027003176;

Chin AC, Espat NJ. Total gastrectomy: options for the restoration of gastrointestinal continuity. Lancet Oncol. 2003 May; 4(5):271-6. PMID: 12732163

Mikhail AT, Babcock TA, Jho DH, Helton WS, Brodsky IG, Espat NJ. Modulation of the ubiquitin-proteasome proteolytic pathway by eicosapentaenoic acid supplementation in a model of progressive malignancy. JPEN J Parenter Enteral Nutr. 2003 Mar-Apr; 27(2):105-9. PMID: 12665165; DOI: 10.1177/0148607103027002105;

Jho D, Babcock TA, Helton WS, Espat NJ. Omega-3 fatty acids: implications for the treatment of tumor-associated inflammation. Am Surg. 2003 Jan; 69(1):32-6. PMID: 12575777

Sturgeon C, Helton WS, Lamba A, Chejfec G, Espat NJ. Early experience employing a linear hepatic parenchyma coagulation device. J Hepatobiliary Pancreat Surg. 2003; 10(1):81-6. PMID: 12827477; DOI: 10.1007/s10534-002-0823-7;

Espat NJ, Lewis JJ, Leung D, Woodruff JM, Antonescu CR, Shia J, Brennan MF. Conventional hemangiopericytoma: modern analysis of outcome. Cancer. 2002 Oct 15; 95(8):1746-51. PMID: 12365023; DOI: 10.1002/cncr.10867;

Tevar R, Jho DH, Babcock T, Helton WS, Espat NJ. Omega-3 fatty acid supplementation reduces tumor growth and vascular endothelial growth factor expression in a model of progressive non-metastasizing malignancy. JPEN J Parenter Enteral Nutr. 2002 Sep-Oct; 26(5):285-9. PMID: 12216707

Jho DH, Babcock TA, Tevar R, Helton WS, Espat NJ. Eicosapentaenoic acid supplementation reduces tumor volume and attenuates cachexia in a rat model of progressive non-metastasizing malignancy. JPEN J Parenter Enteral Nutr. 2002 Sep-Oct; 26(5):291-7. PMID: 12216709; DOI: 10.1177/0148607102026005291;

Babcock TA, Novak T, Ong E, Jho DH, Helton WS, Espat NJ. Modulation of lipopolysaccharide-stimulated macrophage tumor necrosis factor-alpha production by omega-3 fatty acid is associated with differential cyclooxygenase-2 protein expression and is independent of interleukin-10. J Surg Res. 2002 Sep; 107(1):135-9. PMID: 12384076

Novak TE, Babcock TA, Jho DH, Helton WS, Espat NJ. NF-kappa B inhibition by omega -3 fatty acids modulates LPS-stimulated macrophage TNF-alpha transcription. Am J Physiol Lung Cell Mol Physiol. 2003 Jan; 284(1):L84-9. PMID: 12388359; DOI: 10.1152/ajplung.00077.2002;

Silverstein JC, Dech F, Edison M, Jurek P, Helton WS, Espat NJ. Virtual reality: immersive hepatic surgery educational environment. Surgery. 2002 Aug; 132(2):274-7. PMID: 12219023

Espat NJ, Bilsky M, Lewis JJ, Leung D, Brennan MF. Soft tissue sarcoma brain metastases. Prevalence in a cohort of 3829 patients. Cancer. 2002 May 15; 94(10):2706-11. PMID: 12173340

Merola A, O'Brien MF, Castro BA, Smith DA, Eule JM, Lowe TG, Dwyer AP, Haher TR, Espat NJ. Histologic characterization of acute spinal cord injury treated with intravenous methylprednisolone. J Orthop Trauma. 2002 Mar; 16(3):155-61. PMID: 11880777

Babcock TA, Helton WS, Hong D, Espat NJ. Omega-3 fatty acid lipid emulsion reduces LPS-stimulated macrophage TNF-alpha production. Surg Infect (Larchmt). 2002; 3(2):145-9. PMID: 12519481; DOI: 10.1089/109629602760105817;

Helton WS, Espat NJ. Defining mechanisms of omega-3 fatty-acid activity. Nutrition. 2001 Jul-Aug; 17(7-8):674. PMID: 11448595

Molinari M, Helton WS, Espat NJ. Palliative strategies for locally advanced unresectable and metastatic pancreatic cancer. Surg Clin North Am. 2001 Jun; 81(3):651-66. PMID: 11459279

Babcock T, Helton WS, Espat NJ. Eicosapentaenoic acid (EPA): an antiinflammatory omega-3 fat with potential clinical applications. Nutrition. 2000 Nov-Dec; 16(11-12):1116-8. PMID: 11118844

Molinari M, Ong A, Farolan MJ, Helton WS, Espat NJ. Pancreatic heterotopia and other uncommon causes of non-malignant biliary obstruction. Surg Oncol. 2000 Nov; 9(3):135-42. PMID: 11356342

Welborn MB, Oldenburg HS, Hess PJ, Huber TS, Martin TD, Rauwerda JA, Wesdorp RI, Espat NJ, Copeland EM, Moldawer LL, Seeger JM. The relationship between visceral ischemia, proinflammatory cytokines, and organ injury in patients undergoing thoracoabdominal aortic aneurysm repair. Crit Care Med. 2000 Sep; 28(9):3191-7. PMID: 11008981

Espat NJ, Lewis JJ, Woodruff JM, Antonescu C, Xia J, Leung D, Brennan MF. Confirmed angiosarcoma: prognostic factors and outcome in 50 prospectively followed patients. Sarcoma. 2000; 4(4):173-7. PMID: 18521298

Espat NJ, Lewis JJ. The biological significance of failure at the primary site on ultimate survival in soft tissue sarcoma. Semin Radiat Oncol. 1999 Oct; 9(4):369-77. PMID: 10516384

Espat NJ, Brennan MF, Conlon KC. Patients with laparoscopically staged unresectable pancreatic adenocarcinoma do not require subsequent surgical biliary or gastric bypass. J Am Coll Surg. 1999 Jun; 188(6):649-55; discussion 655-7. PMID: 10359358

Espat NJ, Karpeh M. Reconstruction following total gastrectomy: a review and summary of the randomized prospective clinical trials. Surg Oncol. 1998 Jul-Aug; 7(1-2):65-9. PMID: 10421508

Kaibara A, Espat NJ, Auffenberg T, Abouhamze AS, Martin D, Kalra S, Moldawer LL. Interleukin 6, but not ciliary neurotrophic factor or leukaemia inhibitory factor, is responsible for the acute phase response to turpentine-induced myositis. Cytokine. 1998 Jun; 10(6):452-6. PMID: 9632532

Espat NJ, Auffenberg T, Rosenberg JJ, Rogy M, Martin D, Fang CH, Hasselgren PO, Copeland EM, Moldawer LL. Ciliary neurotrophic factor is catabolic and shares with IL-6 the capacity to induce an acute phase response. Am J Physiol. 1996 Jul; 271(1 Pt 2):R185-90. PMID: 8760219; DOI: 10.1152/ajpregu.1996.271.1.R185;

Espat NJ, Watkins KT, Lind DS, Weis JK, Copeland EM, Souba WW. Dietary modulation of amino acid transport in rat and human liver. J Surg Res. 1996 Jun; 63(1):263-8. PMID: 8661208; DOI: 10.1006/jsre.1996.0258;

Espat NJ, Auffenberg T, Abouhamze A, Baumhofer J, Moldawer LL, Howard RJ. A role for tumor necrosis factor-alpha in the increased mortality associated with Vibrio vulnificus infection in the presence of hepatic dysfunction. Ann Surg. 1996 Apr; 223(4):428-33. PMID: 8633922; PMCID: PMC1235139; DOI: 10.1097/00000658-199604000-00012;

Espat NJ, Cendan JC, Beierle EA, Auffenberg TA, Rosenberg J, Russell D, Kenney JS, Fischer E, Montegut W, Lowry SF, et al. PEG-BP-30 monotherapy attenuates the cytokine-mediated inflammatory cascade in baboon Escherichia coli septic shock. J Surg Res. 1995 Jul; 59(1):153-8. PMID: 7630120

Espat NJ, Cheng G, Kelley MC, Vogel SB, Sninsky CA, Hocking MP. Vasoactive intestinal peptide and substance P receptor antagonists improve postoperative ileus. J Surg Res. 1995 Jun; 58(6):719-23. PMID: 7540700

Rogy MA, Auffenberg T, Espat NJ, Philip R, Remick D, Wollenberg GK, Copeland EM, Moldawer LL. Human tumor necrosis factor receptor (p55) and interleukin 10 gene transfer in the mouse reduces mortality to lethal endotoxemia and also attenuates local inflammatory responses. J Exp Med. 1995 Jun 1; 181(6):2289-93.View Related Profiles.

Remick, Daniel
Espat, Nocif

PMID: 7760015; PMCID: PMC2192075

Espat NJ, Moldawer LL, Copeland EM. Cytokine-mediated alterations in host metabolism prevent nutritional repletion in cachectic cancer patients. J Surg Oncol. 1995 Feb; 58(2):77-82. PMID: 7844987

Espat NJ, Bode BP, Lind DS, Copeland EM, Souba WW. Normalization of tumor-induced increases in hepatic amino acid transport after surgical resection. Ann Surg. 1995 Jan; 221(1):50-8. PMID: 7826161

Espat NJ, Copeland EM, Moldawer LL. Tumor necrosis factor and cachexia: a current perspective. Surg Oncol. 1994 Oct; 3(5):255-62. PMID: 7889218

Espat NJ, Rogy MA, Copeland EM, Moldawer LL. CMNSG Guest Lecture. Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist. Proc Nutr Soc. 1994 Jul; 53(2):393-400. PMID: 7972153

Espat NJ, Copeland EM, Souba WW. Accelerated hepatic arginine transport in the tumor-bearing rat. Ann Surg Oncol. 1994 Mar; 1(2):147-56. PMID: 7834440

Espat NJ, Copeland EM, Souba WW. Harry M. Vars Research Award. Influence of fasting on glutamine transport in rat liver. JPEN J Parenter Enteral Nutr. 1993 Nov-Dec; 17(6):493-500. PMID: 8301800

Inoue Y, Espat NJ, Frohnapple DJ, Epstein H, Copeland EM, Souba WW. Effect of total parenteral nutrition on amino acid and glucose transport by the human small intestine. Ann Surg. 1993 Jun; 217(6):604-12; discussion 612-4. PMID: 8507109

Chen MK, Espat NJ, Bland KI, Copeland EM, Souba WW. Influence of progressive tumor growth on glutamine metabolism in skeletal muscle and kidney. Ann Surg. 1993 Jun; 217(6):655-66; discussion 666-7. PMID: 8099476

Dudrick PS, Inoue Y, Espat NJ, Souba WW. Na(+)-dependent glutamine transport in the liver of tumour-bearing rats. Surg Oncol. 1993; 2(3):205-15. PMID: 8252210

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 115 publications over 28 distinct years, with a maximum of 10 publications in 2007

Bar chart showing 115 publications over 28 distinct years, with a maximum of 10 publications in 2007

Year	Publications
1993	4
1994	3
1995	5
1996	3
1998	2
1999	2
2000	4
2001	2
2002	9
2003	9
2004	7
2005	5
2006	7
2007	10
2008	7
2009	7
2010	5
2011	4
2012	3
2013	4
2014	1
2015	1
2016	3
2017	2
2018	2
2019	1
2020	2
2022	1

Contact for Mentoring:

401.456.2000

Download vCard

Espat's Networks

Click the "See All" links for more information and interactive visualizations

Concepts

See all (546) concept(s)

Co-Authors

See all (7) people

Similar People

See all (60) people