Nikhil C. Munshi, MD
Adjunct Associate Professor
Boston University School of Medicine
Dept of Medicine
Hematology & Medical Oncology

MBBS, Maharaja Sayajirao University
MD, Maharaja Sayajirao University

Dr. Nikhil Munshi received his medical degree from Maharaja Sayajirao University, followed by an internship and residency in internal medicine at Shri Sayaji General Hospital and Maharaja University in India. He then completed an oncology fellowship at Johns Hopkins Ocology Center, and an hematology/oncology fellowhip at Indiana University Medical Center. Dr. Munshi is currently professor of medicine in the Department of Medicine at Harvard Medical School, as well as an attending physician at VA Boston Healthcare System and Dana-Farber Cancer Institute.

A diplomate of American Board of Internal Medicine, Dr. Munshi is also on the Board of Directors of the International Myeloma Society. He is a member of numerous professional associations including the Indian Medical Association, Physician’s Association of India, Indian Association of Clinical Oncology, American Medical Association, American Society of Clinical Oncology, and the American Society of Hematology, among others. In addition, he is on the editorial board of Clinical Lymphoma and Myeloma and Personalized Medicine in Oncology and is an ad hoc reviewer for numerous professional journals.

Dr. Munshi’s current laboratory research and clinical activities specialize in plasma cell disorders with a focus on understanding oncogenomic changes in myeloma and developing a translational research programs in myeloma. He has also established a Myeloma Initiative at Veterans Administration Hospitals, a comprehensive program bringing together, for the first time, all major VA hospitals across the country to focus on cutting-edge joint clinical studies.

VA Boston Healthcare System

Integrative Oncogenomics of Multiple Myeloma
SPORE in Multiple Myeloma
Molecular Manipulation to Enhance Anti-Myeloma Response

Yr Title Project-Sub Proj Pubs
2021 Molecular Manipulation to Enhance Anti-Myeloma Response 5I01BX001584-08 40
2021 Integrative Oncogenomics of Multiple Myeloma 5P01CA155258-10 229
2021 Core 1: Administrative and Communication Core 5P01CA155258-10-5939 229
2021 Project 4. Targeting genomic instability and evolution in myeloma 5P01CA155258-10-5947 229
2021 SPORE in Multiple Myeloma 5P50CA100707-18 422
2021 Tissue Banking Core 5P50CA100707-18-8564 422
2021 Targeting AP Nuclease, a Mediator of Genomic Instability in MM 5P50CA100707-18-8567 422
2020 Molecular Manipulation to Enhance Anti-Myeloma Response 5I01BX001584-07 40
2020 Integrative Oncogenomics of Multiple Myeloma 5P01CA155258-09 229
2020 Core 1: Administrative and Communication Core 5P01CA155258-09-5939 229
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Hofste Op Bruinink D, Kuiper R, van Duin M, Cupedo T, van der Velden VHJ, Hoogenboezem R, van der Holt B, Beverloo HB, Valent ET, Vermeulen M, Gay F, Broijl A, Avet-Loiseau H, Munshi NC, Musto P, Moreau P, Zweegman S, van de Donk NWCJ, Sonneveld P. Identification of High-Risk Multiple Myeloma With a Plasma Cell Leukemia-Like Transcriptomic Profile. J Clin Oncol. 2022 Mar 31; JCO2101217. PMID: 35357885
  2. Munshi M, Liu X, Kofides A, Tsakmaklis N, Guerrera ML, Hunter ZR, Palomba ML, Argyropoulos KV, Patterson CJ, Canning AG, Meid KE, Gustine J, Branagan AR, Flynn C, Sarosiek S, Castillo JJ, Wang J, Buhrlage S, Gray NS, Munshi NC, Anderson KC, Treon SP, Yang G. A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas. Blood Adv. 2022 Mar 07.View Related Profiles. PMID: 35255496
  3. Delforge M, Shah N, Miguel JSF, Braverman J, Dhanda DS, Shi L, Guo S, Yu P, Liao W, Campbell TB, Munshi NC. Health-related quality of life with idecabtagene vicleucel in relapsed and refractory multiple myeloma. Blood Adv. 2022 02 22; 6(4):1309-1318. PMID: 34933328; PMCID: PMC8864645; DOI: 10.1182/bloodadvances.2021005913;
  4. O'Donnell EK, Shapiro YN, Yee AJ, Nadeem O, Hu BY, Laubach JP, Branagan AR, Anderson KC, Mo CC, Munshi NC, Ghobrial IM, Sperling AS, Agyemang EA, Burke JN, Harrington CC, Richardson PG, Raje NS, El-Jawahri A. Quality of life, psychological distress, and prognostic perceptions in patients with multiple myeloma. Cancer. 2022 May 15; 128(10):1996-2004. PMID: 35167125
  5. Merz M, Merz AMA, Wang J, Wei L, Hu Q, Hutson N, Rondeau C, Celotto K, Belal A, Alberico R, Block AW, Mohammadpour H, Wallace PK, Tario J, Luce J, Glenn ST, Singh P, Herr MM, Hahn T, Samur M, Munshi N, Liu S, McCarthy PL, Hillengass J. Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma. Nat Commun. 2022 02 10; 13(1):807. PMID: 35145077; PMCID: PMC8831582; DOI: 10.1038/s41467-022-28266-z;
  6. Cavo M, San-Miguel J, Usmani SZ, Weisel K, Dimopoulos MA, Avet-Loiseau H, Paiva B, Bahlis NJ, Plesner T, Hungria V, Moreau P, Mateos MV, Perrot A, Iida S, Facon T, Kumar S, van de Donk NWCJ, Sonneveld P, Spencer A, Krevvata M, Heuck C, Wang J, Ukropec J, Kobos R, Sun S, Qi M, Munshi N. Prognostic value of minimal residual disease negativity in myeloma: combined analysis of POLLUX, CASTOR, ALCYONE, and MAIA. Blood. 2022 02 10; 139(6):835-844. PMID: 34289038; PMCID: PMC8832474; DOI: 10.1182/blood.2021011101;
  7. Wu JT, La J, Branch-Elliman W, Huhmann LB, Han SS, Parmigiani G, Tuck DP, Brophy MT, Do NV, Lin AY, Munshi NC, Fillmore NR. Association of COVID-19 Vaccination With SARS-CoV-2 Infection in Patients With Cancer: A US Nationwide Veterans Affairs Study. JAMA Oncol. 2022 02 01; 8(2):281-286.View Related Profiles. PMID: 34854921; PMCID: PMC8640949; DOI: 10.1001/jamaoncol.2021.5771;
  8. Raje NS, Anaissie E, Kumar SK, Lonial S, Martin T, Gertz MA, Krishnan A, Hari P, Ludwig H, O'Donnell E, Yee A, Kaufman JL, Cohen AD, Garderet L, Wechalekar AF, Terpos E, Khatry N, Niesvizky R, Yi Q, Joshua DE, Saikia T, Leung N, Engelhardt M, Mothy M, Branagan A, Chari A, Reiman AJ, Lipe B, Richter J, Rajkumar SV, Miguel JS, Anderson KC, Stadtmauer EA, Prabhala RH, McCarthy PL, Munshi NC. Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group. Lancet Haematol. 2022 Feb; 9(2):e143-e161. PMID: 35114152
  9. Yan Y, Qin X, Liu J, Fan H, Yan W, Liu L, Du C, Yu Z, Xu Y, Hao M, Deng S, Sui W, Lyu R, Liu W, Wang Q, Zou D, Hu L, Wang J, Tai YT, Anderson KC, Zhang L, Cheng T, Zetterberg A, Munshi NC, Qiu L, An G. Clonal phylogeny and evolution of critical cytogenetic aberrations in multiple myeloma at single-cell level by QM-FISH. Blood Adv. 2022 01 25; 6(2):441-451. PMID: 34653241; PMCID: PMC8791565; DOI: 10.1182/bloodadvances.2021004992;
  10. Giesen N, Paramasivam N, Toprak UH, Huebschmann D, Xu J, Uhrig S, Samur M, Bähr S, Fröhlich M, Mughal SS, Mai EK, Jauch A, Müller-Tidow C, Brors B, Munshi N, Goldschmidt H, Weinhold N, Schlesner M, Raab MS. Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities. Haematologica. 2022 Jan 20. PMID: 35045690
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