Lynne Coluccio, PhD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Pharmacology, Physiology & Biophysics

PhD, Rensselaer Polytechnic Institute
MS, Rensselaer Polytechnic Institute
BS, State University of New York at Albany



Lynne Coluccio, PhD, joined the Department of Physiology & Biophysics at BUSM in 2013 as an Associate Professor after Boston Biomedical Research Institute (BBRI), where she had been a Senior Scientist, abruptly closed. While at BBRI, she played a variety of roles including chair of the Faculty Search Committee and a member of the Public Relations Committee. Throughout her career she has mentored dozens of students who have gone into academia, medicine, and teaching.


Myosin 1 in Epithelial Cell-Cell Contact and Polarity
09/16/2015 - 08/31/2020 (PI)
NIH/National Institute of General Medical Sciences
5R01GM111615-04

Role of myosin 1c in adaptation in the inner ear
02/02/2013 - 06/30/2014 (PI)
NIH/National Institute on Deafness & Communication Disorders
7R01DC008793-06



Title


Yr Title Project-Sub Proj Pubs
2018 Myosin I in epithelial cell-cell contact and polarity 5R01GM111615-04 1
2017 Myosin I in epithelial cell-cell contact and polarity 5R01GM111615-03 1
2016 Myosin I in epithelial cell-cell contact and polarity 5R01GM111615-02 1
2015 Myosin I in epithelial cell-cell contact and polarity 1R01GM111615-01A1 1
2012 Role of myosin 1c in adaptation in the inner ear 5R01DC008793-05 9
2012 Role of myosin 1c in adaptation in the inner ear 7R01DC008793-06 9
2011 Role of myosin 1c in adaptation in the inner ear 5R01DC008793-04 9
2010 Role of myosin 1c in adaptation in the inner ear 5R01DC008793-03 9
2009 Role of myosin 1c in adaptation in the inner ear 3R01DC008793-01A2S1 9
2009 Role of myosin 1c in adaptation in the inner ear 5R01DC008793-02 9
Showing 10 of 31 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Tokuo H, Komaba S, Coluccio LM. In pancreatic ß-cells myosin 1b regulates glucose-stimulated insulin secretion by modulating an early step in insulin granule trafficking from the Golgi. Mol Biol Cell. 2021 06 01; 32(12):1210-1220.View Related Profiles. PMID: 33826361; PMCID: PMC8351557; DOI: 10.1091/mbc.E21-03-0094;
     
  2. Coluccio LM. Introduction. Adv Exp Med Biol. 2020; 1239:1-6. PMID: 32451852
     
  3. Coluccio LM. Myosins and Disease. Adv Exp Med Biol. 2020; 1239:245-316. PMID: 32451863
     
  4. Tokuo H, Bhawan J, Coluccio LM. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis. Sci Rep. 2018 Jul 11; 8(1):10449.View Related Profiles. PMID: 29993000; PMCID: PMC6041326; DOI: 10.1038/s41598-018-28717-y;
     
  5. Komaba S, Coluccio LM. Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells. PLoS One. 2015; 10(9):e0138012. PMID: 26361046; PMCID: PMC4567078; DOI: 10.1371/journal.pone.0138012;
     
  6. Tokuo H, Coluccio LM. Myosin-1c regulates the dynamic stability of E-cadherin-based cell-cell contacts in polarized Madin-Darby canine kidney cells. Mol Biol Cell. 2013 Sep; 24(18):2820-33.View Related Profiles. PMID: 23864705; PMCID: PMC3771945; DOI: 10.1091/mbc.E12-12-0884;
     
  7. Chinthalapudi K, Taft MH, Martin R, Heissler SM, Preller M, Hartmann FK, Brandstaetter H, Kendrick-Jones J, Tsiavaliaris G, Gutzeit HO, Fedorov R, Buss F, Knölker HJ, Coluccio LM, Manstein DJ. Mechanism and specificity of pentachloropseudilin-mediated inhibition of myosin motor activity. J Biol Chem. 2011 Aug 26; 286(34):29700-8. PMID: 21680745; PMCID: PMC3191011; DOI: 10.1074/jbc.M111.239210;
     
  8. Adamek N, Geeves MA, Coluccio LM. Myo1c mutations associated with hearing loss cause defects in the interaction with nucleotide and actin. Cell Mol Life Sci. 2011 Jan; 68(1):139-50. PMID: 20640478; PMCID: PMC3014424; DOI: 10.1007/s00018-010-0448-x;
     
  9. Komaba S, Coluccio LM. Localization of myosin 1b to actin protrusions requires phosphoinositide binding. J Biol Chem. 2010 Sep 3; 285(36):27686-93. PMID: 20610386; PMCID: PMC2934636; DOI: 10.1074/jbc.M109.087270;
     
  10. Adamek N, Lieto-Trivedi A, Geeves MA, Coluccio LM. Modification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner ear. Biochemistry. 2010 Feb 9; 49(5):958-71. PMID: 20039646; PMCID: PMC2826812; DOI: 10.1021/bi901803j;
     
Showing 10 of 49 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 49 publications over 29 distinct years, with a maximum of 4 publications in 1999 and 2010

YearPublications
19811
19821
19833
19841
19851
19861
19872
19882
19891
19901
19911
19931
19943
19952
19971
19994
20003
20031
20043
20051
20071
20083
20104
20111
20131
20151
20181
20202
20211

Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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