Konstantin Aizikov | Profiles RNS

Konstantin Aizikov, PhD

R&D Scientist (previously held)

Thermo Fisher Scientific

Websites

	LinkedIn
	ResearchGate
	Google Scholar
	Fourier Transform Mass Spectrometry Lab

Postdoctoral Fellow (Previously held)
Boston University Chobanian & Avedisian School of Medicine

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Keenan MR, Trindade GF, Pirkl A, Newell CL, Jin Y, Aizikov K, Dannhorn A, Zhang J, Matjacic L, Arlinghaus H, Eyres A, Havelund R, Goodwin RJA, Takats Z, Bunch J, Gould AP, Makarov A, Gilmore IS. Orbitrap noise structure and method for noise unbiased multivariate analysis. Nat Commun. 2025 Jul 10; 16(1):6398. PMID: 40640123; PMCID: PMC12246260; DOI: 10.1038/s41467-025-61542-2;

Harking F, Guzman UH, Kraegenbring J, Stewart H, Aizikov K, Koch H, Fort KL, Harder A, Olsen JV. Enhancing Tandem MS Sensitivity and Peptide Identification via Ion Preaccumulation in an Orbitrap Mass Spectrometer. J Proteome Res. 2025 Aug 01; 24(8):4292-4299. PMID: 40583720; PMCID: PMC12322952; DOI: 10.1021/acs.jproteome.5c00186;

Steigerwald S, Sinha A, Fort KL, Zeng WF, Niu L, Wichmann C, Kreutzmann A, Mourad D, Aizikov K, Grinfeld D, Makarov A, Mann M, Meier F. Full Mass Range FSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis. Mol Cell Proteomics. 2024 Feb; 23(2):100713. PMID: 38184013; PMCID: PMC10851225; DOI: 10.1016/j.mcpro.2024.100713;

James VK, Sanders JD, Aizikov K, Fort KL, Grinfeld D, Makarov A, Brodbelt JS. Expanding Orbitrap Collision Cross-Section Measurements to Native Protein Applications Through Kinetic Energy and Signal Decay Analysis. Anal Chem. 2023 May 16; 95(19):7656-7664. PMID: 37133913

Phaneuf CG, Aizikov K, Grinfeld D, Kreutzmann A, Mourad D, Lange O, Dai D, Zhang B, Belenky A, Makarov AA, Ivanov AR. Experimental strategies to improve drug-target identification in mass spectrometry-based thermal stability assays. Commun Chem. 2023 Apr 06; 6(1):64. PMID: 37024568; PMCID: PMC10079678; DOI: 10.1038/s42004-023-00861-1;

Cai R, Huang W, Meder M, Bourgain F, Aizikov K, Riva M, Bianchi F, Ehn M. Improving the Sensitivity of Fourier Transform Mass Spectrometer (Orbitrap) for Online Measurements of Atmospheric Vapors. Anal Chem. 2022 Nov 15; 94(45):15746-15753. PMID: 36342268; PMCID: PMC9670027; DOI: 10.1021/acs.analchem.2c03403;

James VK, Sanders JD, Aizikov K, Fort KL, Grinfeld D, Makarov A, Brodbelt JS. Advancing Orbitrap Measurements of Collision Cross Sections to Multiple Species for Broad Applications. Anal Chem. 2022 Nov 15; 94(45):15613-15620. PMID: 36326832

Wörner TP, Aizikov K, Snijder J, Fort KL, Makarov AA, Heck AJR. Frequency chasing of individual megadalton ions in an Orbitrap analyser improves precision of analysis in single-molecule mass spectrometry. Nat Chem. 2022 May; 14(5):515-522. PMID: 35273389; PMCID: PMC9068510; DOI: 10.1038/s41557-022-00897-1;

Hilkert A, Böhlke JK, Mroczkowski SJ, Fort KL, Aizikov K, Wang XT, Kopf SH, Neubauer C. Exploring the Potential of Electrospray-Orbitrap for Stable Isotope Analysis Using Nitrate as a Model. Anal Chem. 2021 07 06; 93(26):9139-9148. PMID: 34165950

Srzentic K, Nagornov KO, Fornelli L, Lobas AA, Ayoub D, Kozhinov AN, Gasilova N, Menin L, Beck A, Gorshkov MV, Aizikov K, Tsybin YO. Multiplexed Middle-Down Mass Spectrometry as a Method for Revealing Light and Heavy Chain Connectivity in a Monoclonal Antibody. Anal Chem. 2018 11 06; 90(21):12527-12535. PMID: 30252447

Showing 10 of 21 results. Show More

Kelstrup CD, Aizikov K, Batth TS, Kreutzman A, Grinfeld D, Lange O, Mourad D, Makarov AA, Olsen JV. Limits for Resolving Isobaric Tandem Mass Tag Reporter Ions Using Phase-Constrained Spectrum Deconvolution. J Proteome Res. 2018 11 02; 17(11):4008-4016. PMID: 30220210

Sanders JD, Grinfeld D, Aizikov K, Makarov A, Holden DD, Brodbelt JS. Determination of Collision Cross-Sections of Protein Ions in an Orbitrap Mass Analyzer. Anal Chem. 2018 05 01; 90(9):5896-5902. PMID: 29608288

Fornelli L, Ayoub D, Aizikov K, Liu X, Damoc E, Pevzner PA, Makarov A, Beck A, Tsybin YO. Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer. J Proteomics. 2017 Apr 21; 159:67-76. PMID: 28242452; PMCID: PMC5478168; DOI: 10.1016/j.jprot.2017.02.013;

Grinfeld D, Aizikov K, Kreutzmann A, Damoc E, Makarov A. Phase-Constrained Spectrum Deconvolution for Fourier Transform Mass Spectrometry. Anal Chem. 2017 01 17; 89(2):1202-1211. PMID: 27982570; DOI: 10.1021/acs.analchem.6b03636;

Fornelli L, Ayoub D, Aizikov K, Beck A, Tsybin YO. Middle-down analysis of monoclonal antibodies with electron transfer dissociation orbitrap fourier transform mass spectrometry. Anal Chem. 2014 Mar 18; 86(6):3005-12. PMID: 24588056; DOI: 10.1021/ac4036857;

Maxwell E, Tan Y, Tan Y, Hu H, Benson G, Aizikov K, Conley S, Staples GO, Slysz GW, Smith RD, Zaia J. GlycReSoft: a software package for automated recognition of glycans from LC/MS data. PLoS One. 2012; 7(9):e45474.View Related Profiles.

Zaia, Joseph
Aizikov, Konstantin

PMID: 23049804; PMCID: PMC3458864; DOI: 10.1371/journal.pone.0045474;

Fornelli L, Damoc E, Thomas PM, Kelleher NL, Aizikov K, Denisov E, Makarov A, Tsybin YO. Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS. Mol Cell Proteomics. 2012 Dec; 11(12):1758-67. PMID: 22964222; PMCID: PMC3518117; DOI: 10.1074/mcp.M112.019620;

Aizikov K, Smith DF, Chargin DA, Ivanov S, Lin TY, Heeren RM, O'Connor PB. Vacuum compatible sample positioning device for matrix assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry imaging. Rev Sci Instrum. 2011 May; 82(5):054102. PMID: 21639522; PMCID: PMC3117896; DOI: 10.1063/1.3594099;

Smith DF, Aizikov K, Duursma MC, Giskes F, Spaanderman DJ, McDonnell LA, O'Connor PB, Heeren RM. An external matrix-assisted laser desorption ionization source for flexible FT-ICR Mass spectrometry imaging with internal calibration on adjacent samples. J Am Soc Mass Spectrom. 2011 Jan; 22(1):130-7. PMID: 21472551; PMCID: PMC3042104; DOI: 10.1007/s13361-010-0003-x;

Aizikov K, Mathur R, O'Connor PB. The spontaneous loss of coherence catastrophe in Fourier transform ion cyclotron resonance mass spectrometry. J Am Soc Mass Spectrom. 2009 Feb; 20(2):247-56. PMID: 19013078; PMCID: PMC2872030; DOI: 10.1016/j.jasms.2008.09.028;

Aizikov K, O'Connor PB. Use of the filter diagonalization method in the study of space charge related frequency modulation in fourier transform ion cyclotron resonance mass spectrometry. J Am Soc Mass Spectrom. 2006 Jun; 17(6):836-43. PMID: 16603376

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 21 publications over 13 distinct years, with a maximum of 3 publications in 2018 and 2022

Bar chart showing 21 publications over 13 distinct years, with a maximum of 3 publications in 2018 and 2022

Year	Publications
2006	1
2008	1
2011	2
2012	2
2014	1
2016	1
2017	1
2018	3
2021	1
2022	3
2023	2
2024	1
2025	2

Contact for Mentoring:

670 Albany St Biosquare III
Boston MA 02118
Google Map

617.638.6760

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Zaia, Joseph

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