Jimmy W. Crott PhD
Research Instructor
Boston University School of Medicine
Pathology & Laboratory Medicine

PhD, University of Adelaide




I conduct research on the interaction between diet, gut microbiome, colon tumorigenesis and aging and am currently funded by the USDA, NCI and NIA. Ongoing projects involve identifying the active component of a chemoprotective bacterium, understanding the role of gut barrier integrity and tight junction proteins in aging and understanding the role of the gut microbiome in colon cancer prevention by a Mediterranean diet. Future plans involve identifying bacteria with anti-cancer, anti-inflammatory and anti-aging properties and exploiting them to prolong the healthy lifespan.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Simas AM, Crott JW, Sedore C, Rohrbach A, Monaco AP, Gabriel SB, Lennon N, Blumenstiel B, Genco CA. Pooling for SARS-CoV2 Surveillance: Validation and Strategy for Implementation in K-12 Schools. Front Public Health. 2021; 9:789402. PMID: 34976934; PMCID: PMC8718607; DOI: 10.3389/fpubh.2021.789402;
     
  2. Wu X, Ueland PM, Roper J, Koh GY, Liang X, Crott JW, Yilmaz ÖH, Bronson RT, Mason JB. Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice. J Nutr. 2021 12 03; 151(12):3678-3688. PMID: 34590119; DOI: 10.1093/jn/nxab320;
     
  3. Koh GY, Kane AV, Wu X, Crott JW. Parabacteroides distasonis attenuates tumorigenesis, modulates inflammatory markers and promotes intestinal barrier integrity in azoxymethane-treated A/J mice. Carcinogenesis. 2020 07 14; 41(7):909-917. PMID: 32115637; DOI: 10.1093/carcin/bgaa018;
     
  4. Wu X, Koh GY, Huang Y, Crott JW, Bronson RT, Mason JB. The Combination of Curcumin and Salsalate is Superior to Either Agent Alone in Suppressing Pro-Cancerous Molecular Pathways and Colorectal Tumorigenesis in Obese Mice. Mol Nutr Food Res. 2019 04; 63(8):e1801097. PMID: 30680927; DOI: 10.1002/mnfr.201801097;
     
  5. Pfalzer AC, Leung K, Crott JW, Kim SJ, Tai AK, Parnell LD, Kamanu FK, Liu Z, Rogers G, Shea MK, Garcia PE, Mason JB. Incremental Elevations in TNFa and IL6 in the Human Colon and Procancerous Changes in the Mucosal Transcriptome Accompany Adiposity. Cancer Epidemiol Biomarkers Prev. 2018 12; 27(12):1416-1423. PMID: 30291114; DOI: 10.1158/1055-9965.EPI-18-0121;
     
  6. Koh GY, Kane A, Lee K, Xu Q, Wu X, Roper J, Mason JB, Crott JW. Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. Int J Cancer. 2018 10 01; 143(7):1797-1805. PMID: 29696632; DOI: 10.1002/ijc.31559;
     
  7. Pfalzer AC, Crott JW, Koh GY, Smith DE, Garcia PE, Mason JB. Interleukin-1 Signaling Mediates Obesity-Promoted Elevations in Inflammatory Cytokines, Wnt Activation, and Epithelial Proliferation in the Mouse Colon. J Interferon Cytokine Res. 2018 10; 38(10):445-451. PMID: 30328795; DOI: 10.1089/jir.2017.0134;
     
  8. Wu X, Pfalzer AC, Koh GY, Tang S, Crott JW, Thomas MJ, Meydani M, Mason JB. Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice. J Agric Food Chem. 2017 Aug 23; 65(33):7200-7209. PMID: 28745498; DOI: 10.1021/acs.jafc.7b02648;
     
  9. Crott JW. Effects of altered parental folate and one-carbon nutrient status on offspring growth and metabolism. Mol Aspects Med. 2017 02; 53:28-35. PMID: 27865887; DOI: 10.1016/j.mam.2016.11.001;
     
  10. Liu W, Crott JW, Lyu L, Pfalzer AC, Li J, Choi SW, Yang Y, Mason JB, Liu Z. Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and Wnt Pathway in the Intestine of Apc+/1638N Mice: Comparisons and Contrasts. J Cancer. 2016; 7(13):1780-1790. PMID: 27698916; PMCID: PMC5039360; DOI: 10.7150/jca.15792;
     
Showing 10 of 52 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 52 publications over 22 distinct years, with a maximum of 9 publications in 2011

YearPublications
19992
20014
20021
20031
20042
20051
20063
20074
20082
20091
20103
20119
20121
20132
20142
20151
20165
20171
20183
20191
20201
20212

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

microbiome
inflammation
colorectal cancer
aging
healthspan
diet
Contact for Mentoring:

670 Albany St
Boston MA 02118
Google Map


Crott's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Co-Authors
_
Similar People
_
Same Department