PhD, University of Michigan

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Krishnan R, Goodman JL, Mukhopadhyay S, Pacheco CD, Lemke EA, Deniz AA, Lindquist S. Conserved features of intermediates in amyloid assembly determine their benign or toxic states. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11172-7. PMID: 22745165; PMCID: PMC3396487; DOI: 10.1073/pnas.1209527109;
  2. Dumitriu A, Moser C, Hadzi TC, Williamson SL, Pacheco CD, Hendricks AE, Latourelle JC, Wilk JB, Destefano AL, Myers RH. Postmortem Interval Influences a-Synuclein Expression in Parkinson Disease Brain. Parkinsons Dis. 2012; 2012:614212.View Related Profiles. PMID: 22530163; PMCID: PMC3317023; DOI: 10.1155/2012/614212;
  3. Dumitriu A, Pacheco CD, Wilk JB, Strathearn KE, Latourelle JC, Goldwurm S, Pezzoli G, Rochet JC, Lindquist S, Myers RH. Cyclin-G-associated kinase modifies a-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Hum Mol Genet. 2011 Apr 15; 20(8):1478-87.View Related Profiles. PMID: 21258085; PMCID: PMC3063983; DOI: 10.1093/hmg/ddr026;
  4. Elrick MJ, Pacheco CD, Yu T, Dadgar N, Shakkottai VG, Ware C, Paulson HL, Lieberman AP. Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration. Hum Mol Genet. 2010 Mar 1; 19(5):837-47. PMID: 20007718; PMCID: PMC2816612; DOI: 10.1093/hmg/ddp552;
  5. Pacheco CD, Elrick MJ, Lieberman AP. Tau normal function influences Niemann-Pick type C disease pathogenesis in mice and modulates autophagy in NPC1-deficient cells. Autophagy. 2009 May; 5(4):548-50. PMID: 19332999; PMCID: PMC2704906
  6. Pacheco CD, Elrick MJ, Lieberman AP. Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis. Hum Mol Genet. 2009 Mar 1; 18(5):956-65. PMID: 19074461; PMCID: PMC2646181; DOI: 10.1093/hmg/ddn423;
  7. Pacheco CD, Lieberman AP. The pathogenesis of Niemann-Pick type C disease: a role for autophagy? Expert Rev Mol Med. 2008; 10:e26. PMID: 18782459; PMCID: PMC2662713; DOI: 10.1017/S146239940800080X;
  8. Hughes ED, Qu YY, Genik SJ, Lyons RH, Pacheco CD, Lieberman AP, Samuelson LC, Nasonkin IO, Camper SA, Van Keuren ML, Saunders TL. Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line. Mamm Genome. 2007 Aug; 18(8):549-58. PMID: 17828574
  9. Pacheco CD, Lieberman AP. Lipid trafficking defects increase Beclin-1 and activate autophagy in Niemann-Pick type C disease. Autophagy. 2007 Sep-Oct; 3(5):487-9. PMID: 17611388
  10. Pacheco CD, Kunkel R, Lieberman AP. Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects. Hum Mol Genet. 2007 Jun 15; 16(12):1495-503. PMID: 17468177

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