Catherine Grgicak, PhD
Assistant Professor
Boston University School of Medicine
Dept of Anatomy & Neurobiology

PhD, University of Ottawa
MS, University of Alabama at Birmingham

Expertise includes:

Interpretation of complex, low-level DNA signal;
Applications of Laser Microdissection in Forensic DNA Analysis;
Evaluation of Degraded DNA and its effect on forensic DNA mixture interpretation;
Electrochemical Biosensors - Immobilization of DNA on Gold;
Determining the Number of Contributors to complex, low-level DNA signal

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences

Establishing Exclusion Criteria and the Significance of Inclusion: Developing Tools for the Interpretation of Complex DNA Mixtures
01/01/2015 - 12/31/2017 (PI)
Department of Justice/NIJ

Collection Methods and Protocol Optimization for the EasiCollect+ DNA Collection Device
04/11/2016 - 07/20/2017 (PI)
GE Healthcare Bio-Sciences Ltd.

A Tool for Determining the Number of Contributors: Interpreting Complex, Compromised, Low-Template DNA
09/08/2014 - 02/07/2017 (PI)
Department of Defense/ARO

Establishing Exclusion Criteria and Significance of Inclusion for Complex Low-Template DNA Mixtures
01/01/2013 - 03/31/2015 (PI)
Department of Justice/NIJ

Low-temperature DNA mixture interpretation: Determining the number of contributors
01/01/2012 - 08/31/2014 (PI)
Department of Justice/NIJ

Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Norsworthy S, Lun DS, Grgicak CM. Determining the number of contributors to DNA mixtures in the low-template regime: Exploring the impacts of sampling and detection effects. Leg Med (Tokyo). 2018 Feb 08; 32:1-8. PMID: 29453054.
  2. Alfonse LE, Garrett AD, Lun DS, Duffy KR, Grgicak CM. A large-scale dataset of single and mixed-source short tandem repeat profiles to inform human identification strategies: PROVEDIt. Forensic Sci Int Genet. 2018 Jan; 32:62-70. PMID: 29091906.
  3. Peters KC, Swaminathan H, Sheehan J, Duffy KR, Lun DS, Grgicak CM. Production of high-fidelity electropherograms results in improved and consistent DNA interpretation: Standardizing the forensic validation process. Forensic Sci Int Genet. 2017 Nov; 31:160-170. PMID: 28950155.
  4. Duffy KR, Gurram N, Peters KC, Wellner G, Grgicak CM. Exploring STR signal in the single- and multicopy number regimes: Deductions from an in silico model of the entire DNA laboratory process. Electrophoresis. 2017 03; 38(6):855-868. PMID: 27981603; DOI: 10.1002/elps.201600385;.
  5. Alfonse LE, Tejada G, Swaminathan H, Lun DS, Grgicak CM. Inferring the Number of Contributors to Complex DNA Mixtures Using Three Methods: Exploring the Limits of Low-Template DNA Interpretation. J Forensic Sci. 2017 Mar; 62(2):308-316. PMID: 27907229; DOI: 10.1111/1556-4029.13284;.
  6. Swaminathan H, Garg A, Grgicak CM, Medard M, Lun DS. CEESIt: A computational tool for the interpretation of STR mixtures. Forensic Sci Int Genet. 2016 May; 22:149-60. PMID: 26946255; DOI: 10.1016/j.fsigen.2016.02.005;.
  7. Rowan KE, Wellner GA, Grgicak CM. Exploring the Impacts of Ordinary Laboratory Alterations During Forensic DNA Processing on Peak Height Variation, Thresholds, and Probability of Dropout. J Forensic Sci. 2016 Jan; 61(1):177-85. PMID: 26280243; DOI: 10.1111/1556-4029.12899;.
  8. Mönich UJ, Duffy K, Médard M, Cadambe V, Alfonse LE, Grgicak C. Probabilistic characterisation of baseline noise in STR profiles. Forensic Sci Int Genet. 2015 Nov; 19:107-22. PMID: 26218981; DOI: 10.1016/j.fsigen.2015.07.001;.
  9. Swaminathan H, Grgicak CM, Medard M, Lun DS. NOCIt: a computational method to infer the number of contributors to DNA samples analyzed by STR genotyping. Forensic Sci Int Genet. 2015 May; 16:172-80. PMID: 25625964; DOI: 10.1016/j.fsigen.2014.11.010;.
  10. Oechsle CS, Haddad S, Sgueglia JB, Grgicak CM. Screening biological stains with qPCR versus lateral flow immunochromatographic test strips: a quantitative comparison using analytical figures of merit. J Forensic Sci. 2014 Jan; 59(1):199-207. PMID: 24117798; DOI: 10.1111/1556-4029.12284;.
Showing 10 of 24 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 24 publications over 12 distinct years, with a maximum of 3 publications in 2005 and 2013 and 2017

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Forensic DNA Analysis

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

72 E. Concord St Housman (R)
Boston MA 02118
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