Akshay Gupte, PhD, MBBS, MSPH
Assistant Professor
Boston University School of Public Health
Global Health

MD, Maharashtra University of Health Science
PhD, Johns Hopkins University School of Public Health
MSPH, Johns Hopkins University School of Public Health
BA, Maharashtra University of Health Science



Dr. Gupte is a physician-scientist whose research is focused on the intersection of infectious and chronic lung diseases in low- and middle-income settings. He leads several Indo-US collaborative studies to describe the epidemiology and pathogenesis of lung injury in tuberculosis (TB)/HIV/diabetes, measure its impact on poor clinical outcomes, and identify therapeutic and programmatic interventions to improve post-TB lung health and longevity.

Dr. Gupte serves on several multi-national TB/HIV research consortia, such as the TB Transformative Science Working Group of the AIDS Clinical Trials Group (ACTG), Lung Health Working Group of the International Epidemiology Databases to Evaluate AIDS (IeDEA) network, and is Chairperson of the Clinical and Epidemiology Working Group of the RePORT-India TB Research Consortium.

Dr. Gupte completed his medical training in India, Master’s and Doctoral training from the Johns Hopkins Bloomberg School of Public Health, and has previously served as faculty in the Division of Infectious Diseases, Johns Hopkins School of Medicine. He is a 2017 Fogarty Fellow and recipient of the Arthur M. Dannenberg, Jr., Award for excellence in TB research.


Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIV
09/20/2024 - 08/31/2029 (PI)
NIH/National Institute of Allergy & Infectious Diseases
1R01AI184179-01

Phenotype, Progression and Immune Correlates of Post-Tuberculosis Lung Disease
04/05/2023 - 03/31/2026 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R00AI151094-04

TB PuRe: Pulmonary rehabilitation to reduce post-tuberculosis morbidity
09/01/2023 - 08/31/2025 (Subcontract PI)
The Johns Hopkins University NIH NIAID
5R01AI169588-02

TB Aftermath
06/01/2022 - 05/31/2025 (Subcontract PI)
The Johns Hopkins University NIH NIAID
5R01AI143748-03



Title


Yr Title Project-Sub Proj Pubs
2025 Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIV 3R01AI184179-02S1
2025 Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIV 3R01AI184179-02S2
2025 Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIV 5R01AI184179-02
2025 TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity 3R01AI169588-03S2
2025 TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity 3R01AI169588-03S1
2025 TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity 5R01AI169588-03
2024 Interleukin-6 signaling, lung injury, and post-TB lung disease in TB-HIV 1R01AI184179-01
2024 TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity 5R01AI169588-02
2024 Phenotype, Progression and Immune Correlates of Post-Tuberculosis Lung Disease 5R00AI151094-04
2023 TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity 1R01AI169588-01A1
Showing 10 of 13 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Sinha P, Karoly M, Padmapriyadarsini C, Paradkar M, Mave V, Gupte N, Gupta A, Dauphinais M, Babu SP, Gaikwad S, Cox SR, Golub J, Cintron C, Thangakunam B, Ezhumalai K, Ponnuraja C, Tornheim JA, Christopher DJ, Viswanathan V, Ellner JJ, Kornfeld H, Horsburgh CR, Bala Yogendra Shivakumar SV, Salgame P, Bollinger RC, Sarkar S, Gupte AN. Contribution of Key Comorbidities to Unfavorable Treatment Outcomes among Adults with Drug-sensitive Pulmonary Tuberculosis in India: a Prospective Cohort Analysis. Chest. 2025 Sep 10.View Related Profiles. PMID: 40939932; DOI: 10.1016/j.chest.2025.05.055;
     
  2. Cox SR, Moe AH, Gupte AN, Kadam A, Valawalkar S, Gupte N, Lele G, Kendall EA, Baillie C, Barthwal MS, Kakrani A, Mave V, Dowdy DW, Golub JE. A point-of-care prediction tool for recurrent tuberculosis. Clin Infect Dis. 2025 Jul 08. PMID: 40626664; DOI: 10.1093/cid/ciaf353;
     
  3. Tabackman A, Gupte AN, Thangakunam B, Babu SP, Du X, Paradkar M, Shivakumar SVBY, Gaikwad S, Ezhumalai K, Ponnuraja C, Cox S, Gupte N, Tornheim JA, Dauphinais MR, Gupta A, Christopher DJ, Kornfeld H, Mave V, Viswanathan V, Ellner JJ, White LF, Padmapriyadarsini C, Sinha P, Sarkar S. Impact of premorbid nutritional status on TB severity. Int J Tuberc Lung Dis. 2025 May 30; 29(6):265-270.View Related Profiles. PMID: 40495301; DOI: 10.5588/ijtld.24.0592;
     
  4. Mave V, Cox SR, Gupte AN, Golub JE. Addressing post-tuberculosis sequelae among people living with HIV: an unmet need. J Int AIDS Soc. 2025 Mar; 28(3):e26439. PMID: 40123373; PMCID: PMC11931193; DOI: 10.1002/jia2.26439;
     
  5. Prakash Babu S, Ezhumalai K, Raghupathy K, Karoly M, Chinnakali P, Gupte N, Paradkar M, Devarajan A, Dhanasekaran M, Thiruvengadam K, Dauphinais MR, Gupte AN, Shivakumar SB, Thangakunam B, Christopher DJ, Viswanathan V, Mave V, Gaikwad S, Kinikar A, Kornfeld H, Horsburgh CR, Chandrasekaran P, Hochberg NS, Salgame P, Gupta A, Roy G, Ellner J, Sinha P, Sarkar S. Factors Associated With Unfavorable Treatment Outcomes Among Persons With Pulmonary Tuberculosis: A Multicentric Prospective Cohort Study From India. Clin Infect Dis. 2024 Oct 15; 79(4):1034-1038.View Related Profiles. PMID: 38991034; PMCID: PMC11478802; DOI: 10.1093/cid/ciae367;
     
  6. Gupte AN, Nardell EA. Host-Directed Therapies for Posttuberculosis Lung Disease. NEJM Evid. 2024 Sep; 3(9):EVIDe2400181. PMID: 39189856
     
  7. Sinha P, Ezhumalai K, Du X, Ponnuraja C, Dauphinais MR, Gupte N, Sarkar S, Gupta A, Gaikwad S, Thangakunam B, Paradkar M, Christopher DJ, Mave V, Viswanathan V, Ellner JJ, Kornfeld H, Horsburgh CR, Padmapriyadarsini C, Gupte A. Undernourished Household Contacts Are at Increased Risk of Tuberculosis (TB) Disease, but not TB Infection-a Multicenter Prospective Cohort Analysis. Clin Infect Dis. 2024 Jul 19; 79(1):233-236.View Related Profiles. PMID: 38652286; PMCID: PMC11259213; DOI: 10.1093/cid/ciae149;
     
  8. Krishnan S, Gupte N, Paradkar M, Gupte A, Naik M, Raskar S, Suryavanshi N, Pradhan N, Gaikwad S, Karyakarte R, Lokhande R, Luke EH, Thiruvengadam K, Padmapriyadarsini C, Sahasrabudhe T, Barthwal M, Kakrani A, Viswanathan V, Kornfeld H, Gupta A, Golub JE, Mave V. Clinical and laboratory risk factors for pulmonary tuberculosis recurrence in three pooled Indian cohorts. Front Tuberc. 2024; 2. PMID: 40303321; PMCID: PMC12040415; DOI: 10.3389/ftubr.2024.1433975;
     
  9. Krishnan Sonya , Gupte Nikhil , Paradkar Mandar , Gupte Akshay , Naik Mrunmayi , Raskar Swapnil , Suryavanshi Nishi , Pradhan Neeta , Gaikwad Sanjay , Karyakarte Rajesh , Lokhande Rahul , Hanna Luke Elizabeth , Thiruvengadam Kannan , Padmapriyadarsini Chandrasekaran , Sahasrabudhe Tushar , Barthwal Madhusudan , Kakrani ArjunLal , Viswanathan Vijay , Kornfeld Hardy , Gupta Amita , Golub Jonathan E. , Mave Vidya. Clinical and laboratory risk factors for pulmonary tuberculosis recurrence in three pooled Indian cohorts. Frontiers in Tuberculosis. 2024; 2.
  10. Cox SR, Kadam A, Atre S, Gupte AN, Sohn H, Gupte N, Sawant T, Mhadeshwar V, Thompson R, Kendall E, Hofmann C, Suryavanshi N, Kerrigan D, Tripathy S, Kakrani A, Barthwal MS, Mave V, Golub JE. Correction: Tuberculosis (TB) Aftermath: study protocol for a hybrid type I effectiveness-implementation non-inferiority randomized trial in India comparing two active case finding (ACF) strategies among individuals treated for TB and their household contacts. Trials. 2024 Mar 11; 25(1):178. PMID: 38468342; PMCID: PMC10929208; DOI: 10.1186/s13063-024-07984-3;
     
Showing 10 of 57 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 57 publications over 11 distinct years, with a maximum of 10 publications in 2019

YearPublications
20122
20162
20171
20182
201910
20208
20219
20227
20236
20246
20254


2018 Fogarty International Center, NIH: Fogarty Global Health Fellowship
2017 Johns Hopkins School of Medicine: Arthur M. Dannenberg Jr. Award for Tuberculosis Research
2016 Conference on Retroviruses and Opportunistic Infections: CROI Young Investigator Award
2014 Johns Hopkins School of Medicine: Ujala Scholar
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