Keywords
Last Name

Richard Goldstein, PhD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentPediatrics
DivisionInfectious Diseases
Address670 Albany St Biosquare III
Boston MA 02118
Phone(617) 414-6484
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

InstitutionBoston Medical Center

 Awards and Honors

Start-EndDescription
2009-2013The Hartwell Foundation: Hartwell Biomedical Investigator
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Lundström SL, Li J, Månsson M, Figueira M, Leroy M, Goldstein R, Hood DW, Moxon ER, Richards JC, Schweda EK. Application of capillary electrophoresis mass spectrometry and liquid chromatography multiple-step tandem electrospray mass spectrometry to profile glycoform expression during Haemophilus influenzae pathogenesis in the chinchilla model of experimental otitis media. Infect Immun. 2008 Jul; 76(7):3255-67. PMID: 18458064.
    View in: PubMed
  2. Bouchet V, Huot H, Goldstein R. Molecular genetic basis of ribotyping. Clin Microbiol Rev. 2008 Apr; 21(2):262-73, table of contents. PMID: 18400796.
    View in: PubMed
  3. Lipsitch M, O'Neill K, Cordy D, Bugalter B, Trzcinski K, Thompson CM, Goldstein R, Pelton S, Huot H, Bouchet V, Reid R, Santosham M, O'Brien KL. Strain characteristics of Streptococcus pneumoniae carriage and invasive disease isolates during a cluster-randomized clinical trial of the 7-valent pneumococcal conjugate vaccine. J Infect Dis. 2007 Oct 15; 196(8):1221-7. PMID: 17955441.
    View in: PubMed
  4. Pelton SI, Huot H, Finkelstein JA, Bishop CJ, Hsu KK, Kellenberg J, Huang SS, Goldstein R, Hanage WP. Emergence of 19A as virulent and multidrug resistant Pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2007 Jun; 26(6):468-72. PMID: 17529860.
    View in: PubMed
  5. Leroy M, Cabral H, Figueira M, Bouchet V, Huot H, Ram S, Pelton SI, Goldstein R. Multiple consecutive lavage samplings reveal greater burden of disease and provide direct access to the nontypeable Haemophilus influenzae biofilm in experimental otitis media. Infect Immun. 2007 Aug; 75(8):4158-72. PMID: 17517860.
    View in: PubMed
  6. Hanage WP, Huang SS, Lipsitch M, Bishop CJ, Godoy D, Pelton SI, Goldstein R, Huot H, Finkelstein JA. Diversity and antibiotic resistance among nonvaccine serotypes of Streptococcus pneumoniae carriage isolates in the post-heptavalent conjugate vaccine era. J Infect Dis. 2007 Feb 1; 195(3):347-52. PMID: 17205472.
    View in: PubMed
  7. Figueira MA, Ram S, Goldstein R, Hood DW, Moxon ER, Pelton SI. Role of complement in defense of the middle ear revealed by restoring the virulence of nontypeable Haemophilus influenzae siaB mutants. Infect Immun. 2007 Jan; 75(1):325-33. PMID: 17088344.
    View in: PubMed
  8. Bouchet V, Hood DW, Li J, Brisson JR, Randle GA, Martin A, Li Z, Goldstein R, Schweda EK, Pelton SI, Richards JC, Moxon ER. Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8898-903. PMID: 12855765.
    View in: PubMed
  9. Cody AJ, Field D, Feil EJ, Stringer S, Deadman ME, Tsolaki AG, Gratz B, Bouchet V, Goldstein R, Hood DW, Moxon ER. High rates of recombination in otitis media isolates of non-typeable Haemophilus influenzae. Infect Genet Evol. 2003 May; 3(1):57-66. PMID: 12797973.
    View in: PubMed
  10. Meats E, Feil EJ, Stringer S, Cody AJ, Goldstein R, Kroll JS, Popovic T, Spratt BG. Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J Clin Microbiol. 2003 Apr; 41(4):1623-36. PMID: 12682154.
    View in: PubMed
  11. Feil EJ, Holmes EC, Bessen DE, Chan MS, Day NP, Enright MC, Goldstein R, Hood DW, Kalia A, Moore CE, Zhou J, Spratt BG. Recombination within natural populations of pathogenic bacteria: short-term empirical estimates and long-term phylogenetic consequences. Proc Natl Acad Sci U S A. 2001 Jan 2; 98(1):182-7. PMID: 11136255.
    View in: PubMed
  12. Bolduc GR, Bouchet V, Jiang RZ, Geisselsoder J, Truong-Bolduc QC, Rice PA, Pelton SI, Goldstein R. Variability of outer membrane protein P1 and its evaluation as a vaccine candidate against experimental otitis media due to nontypeable Haemophilus influenzae: an unambiguous, multifaceted approach. Infect Immun. 2000 Aug; 68(8):4505-17. PMID: 10899849.
    View in: PubMed
  13. Holmes A, Nolan R, Taylor R, Finley R, Riley M, Jiang RZ, Steinbach S, Goldstein R. An epidemic of burkholderia cepacia transmitted between patients with and without cystic fibrosis. J Infect Dis. 1999 May; 179(5):1197-205. PMID: 10191223.
    View in: PubMed
  14. Holmes A, Govan J, Goldstein R. Agricultural use of Burkholderia (Pseudomonas) cepacia: a threat to human health? Emerg Infect Dis. 1998 Apr-Jun; 4(2):221-7. PMID: 9621192.
    View in: PubMed
  15. Sun L, Jiang RZ, Steinbach S, Holmes A, Campanelli C, Forstner J, Sajjan U, Tan Y, Riley M, Goldstein R. The emergence of a highly transmissible lineage of cbl+ Pseudomonas (Burkholderia) cepacia causing CF centre epidemics in North America and Britain. Nat Med. 1995 Jul; 1(7):661-6. PMID: 7585148.
    View in: PubMed
  16. Goldstein R, Sun L, Jiang RZ, Sajjan U, Forstner JF, Campanelli C. Structurally variant classes of pilus appendage fibers coexpressed from Burkholderia (Pseudomonas) cepacia. J Bacteriol. 1995 Feb; 177(4):1039-52. PMID: 7532167.
    View in: PubMed
  17. Sajjan US, Sun L, Goldstein R, Forstner JF. Cable (cbl) type II pili of cystic fibrosis-associated Burkholderia (Pseudomonas) cepacia: nucleotide sequence of the cblA major subunit pilin gene and novel morphology of the assembled appendage fibers. J Bacteriol. 1995 Feb; 177(4):1030-8. PMID: 7532166.
    View in: PubMed
  18. Steinbach S, Sun L, Jiang RZ, Flume P, Gilligan P, Egan TM, Goldstein R. Transmissibility of Pseudomonas cepacia infection in clinic patients and lung-transplant recipients with cystic fibrosis. N Engl J Med. 1994 Oct 13; 331(15):981-7. PMID: 7521938.
    View in: PubMed
  19. Agarwal M, Arthur M, Arbeit RD, Goldstein R. Regulation of icosahedral virion capsid size by the in vivo activity of a cloned gene product. Proc Natl Acad Sci U S A. 1990 Apr; 87(7):2428-32. PMID: 2181437.
    View in: PubMed
  20. Arbeit RD, Arthur M, Dunn R, Kim C, Selander RK, Goldstein R. Resolution of recent evolutionary divergence among Escherichia coli from related lineages: the application of pulsed field electrophoresis to molecular epidemiology. J Infect Dis. 1990 Feb; 161(2):230-5. PMID: 1967621.
    View in: PubMed
  21. Arthur M, Arbeit RD, Kim C, Beltran P, Crowe H, Steinbach S, Campanelli C, Wilson RA, Selander RK, Goldstein R. Restriction fragment length polymorphisms among uropathogenic Escherichia coli isolates: pap-related sequences compared with rrn operons. Infect Immun. 1990 Feb; 58(2):471-9. PMID: 1967594.
    View in: PubMed
  22. Gutmann L, Agarwal M, Arthur M, Campanelli C, Goldstein R. A phasmid shuttle vector for the cloning of complex operons in Salmonella. Plasmid. 1990 Jan; 23(1):42-58. PMID: 2190245.
    View in: PubMed
  23. Arthur M, Campanelli C, Arbeit RD, Kim C, Steinbach S, Johnson CE, Rubin RH, Goldstein R. Structure and copy number of gene clusters related to the pap P-adhesin operon of uropathogenic Escherichia coli. Infect Immun. 1989 Feb; 57(2):314-21. PMID: 2563255.
    View in: PubMed
  24. Arthur M, Johnson CE, Rubin RH, Arbeit RD, Campanelli C, Kim C, Steinbach S, Agarwal M, Wilkinson R, Goldstein R. Molecular epidemiology of adhesin and hemolysin virulence factors among uropathogenic Escherichia coli. Infect Immun. 1989 Feb; 57(2):303-13. PMID: 2563254.
    View in: PubMed
  25. Lagos R, Goldstein R. Evolutionary relationship between plasmids and phages: phasmid P4 as a model. Arch Biol Med Exp (Santiago). 1987; 20(3-4):325-32. PMID: 8816073.
    View in: PubMed
  26. Lagos R, Jiang RZ, Kim S, Goldstein R. Rho-dependent transcription termination of a bacterial operon is antagonized by an extrachromosomal gene product. Proc Natl Acad Sci U S A. 1986 Dec; 83(24):9561-5. PMID: 3540944.
    View in: PubMed
  27. Lagos R, Goldstein R. Phasmid P4: manipulation of plasmid copy number and induction from the integrated state. J Bacteriol. 1984 Apr; 158(1):208-15. PMID: 6370957.
    View in: PubMed
  28. Geisselsoder J, Sedivy JM, Walsh RB, Goldstein R. Capsid structure of satellite phage P4 and its P2 helper. J Ultrastruct Res. 1982 May; 79(2):165-73. PMID: 7077742.
    View in: PubMed
  29. Goldstein R, Sedivy J, Ljungquist E. Propagation of satellite phage P4 as a plasmid. Proc Natl Acad Sci U S A. 1982 Jan; 79(2):515-9. PMID: 7043461.
    View in: PubMed
  30. Calendar R, Ljungquist E, Deho G, Usher DC, Goldstein R, Youderian P, Sironi G, Six EW. Lysogenization by satellite phage P4. Virology. 1981 Aug; 113(1):20-38. PMID: 7023020.
    View in: PubMed
  31. Geisselsoder J, Youdarian P, Dehò G, Chidambaram M, Goldstein R, Ljungquist E. Mutants of satellite virus P4 that cannot derepress their bacteriophage P2 helper. J Mol Biol. 1981 May 5; 148(1):1-19. PMID: 7310867.
    View in: PubMed
  32. Geisselsoder J, Chidambaram M, Goldstein R. Transcriptional control of capsid size in the P2:P4 bacteriophage system. J Mol Biol. 1978 Dec 15; 126(3):447-56. PMID: 370404.
    View in: PubMed
  33. Diana C, Dehò G, Geisselsoder J, Tinelli L, Goldstein R. Viral interference at the level of capsid size determination by satellite phage P4. J Mol Biol. 1978 Dec 15; 126(3):433-45. PMID: 745236.
    View in: PubMed
  34. Shore D, Dehò G, Tsipis J, Goldstein R. Determination of capsid size by satellite bacteriophage P4. Proc Natl Acad Sci U S A. 1978 Jan; 75(1):400-4. PMID: 272656.
    View in: PubMed
  35. Lengyel JA, Goldstein RN, Marsh M, Calendar R. Structure of the bacteriophage P2 tail. Virology. 1974 Nov; 62(1):161-74. PMID: 4607804.
    View in: PubMed
  36. Pruss G, Goldstein RN, Calendar R. In vitro packaging of satellite phage P4 DNA. Proc Natl Acad Sci U S A. 1974 Jun; 71(6):2367-71. PMID: 4526304.
    View in: PubMed
  37. Goldstein R, Lengyel J, Pruss G, Barrett K, Calendar R, Six E. Head size determination and the morphogenesis of satellite phage P4. Curr Top Microbiol Immunol. 1974; (68):59-75. PMID: 4448101.
    View in: PubMed
  38. Pruss G, Barrett K, Lengyel J, Goldstein R, Calendar R. Phage head size determination and head protein cleavage in vitro. J Supramol Struct. 1974; 2(2-4):337-48. PMID: 4612251.
    View in: PubMed
  39. Lengyel JA, Goldstein RN, Marsh M, Sunshine MG, Calendar R. Bacteriophage P2 head morphogenesis: cleavage of the major capsid protein. Virology. 1973 May; 53(1):1-23. PMID: 4574872.
    View in: PubMed
  40. Gibbs W, Goldstein RN, Wiener R, Lindqvist B, Calendar R. Satellite bacteriophage P4: characterization of mutants in two essential genes. Virology. 1973 May; 53(1):24-39. PMID: 4574874.
    View in: PubMed
  41. Barrett K, Calendar R, Gibbs W, Goldstein RN, Lindqvist B, Six E. Helper-dependent bacteriophage P4: a model satellite virus and its implications for animal virology. Prog Med Virol. 1973; 15:309-30. PMID: 4348876.
    View in: PubMed
  42. Goldstein RN, Stefanovic S, Kallenbach NR. On the conformation of transfer RNA in solution: dependence of denaturation temperature and structural parameters of mixed and formylmethionyl Escherichia coli transfer RNA on sodium ion concentration. J Mol Biol. 1972 Aug 21; 69(2):217-36. PMID: 4560948.
    View in: PubMed
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