Keywords
Last Name

Linda J. Heffner, MD, PhD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentObstetrics & Gynecology
DivisionMaternal & Fetal
Address85 E. Concord St
Boston MA 02118
Phone(617) 414-5175
ORCID ORCID Icon0000-0001-9623-7210
Other Positions
TitleProfessor
InstitutionBoston University School of Medicine
DepartmentPhysiology & Biophysics

TitleActive Staff Privileges
InstitutionBoston Medical Center
DepartmentObstetrics & Gynecology

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Okeigwe I, Wang C, Politch JA, Heffner LJ, Kuohung W. Physician-scientists in obstetrics and gynecology: predictors of success in obtaining independent research funding. Am J Obstet Gynecol. 2017 Mar 16. PMID: 28315665.
    View in: PubMed
  2. Parker MG, Ouyang F, Pearson C, Gillman MW, Belfort MB, Hong X, Wang G, Heffner L, Zuckerman B, Wang X. Prepregnancy body mass index and risk of preterm birth: association heterogeneity by preterm subgroups. BMC Pregnancy Childbirth. 2014; 14:153. PMID: 24779674.
    View in: PubMed
  3. Yu Y, Zhang S, Wang G, Hong X, Mallow EB, Walker SO, Pearson C, Heffner L, Zuckerman B, Wang X. The combined association of psychosocial stress and chronic hypertension with preeclampsia. Am J Obstet Gynecol. 2013 Nov; 209(5):438.e1-438.e12. PMID: 23850528.
    View in: PubMed
  4. Li S, Rosenberg L, Palmer JR, Phillips GS, Heffner LJ, Wise LA. Central adiposity and other anthropometric factors in relation to risk of macrosomia in an African American population. Obesity (Silver Spring). 2013 Jan; 21(1):178-84. PMID: 23505184.
    View in: PubMed
  5. Pecci CC, Mottl-Santiago J, Culpepper L, Heffner L, McMahan T, Lee-Parritz A. The birth of a collaborative model: obstetricians, midwives, and family physicians. Obstet Gynecol Clin North Am. 2012 Sep; 39(3):323-34. PMID: 22963692.
    View in: PubMed
  6. Tsai HJ, Hong X, Chen J, Liu X, Pearson C, Ortiz K, Hirsch E, Heffner L, Weeks DE, Zuckerman B, Wang X. Role of African ancestry and gene-environment interactions in predicting preterm birth. Obstet Gynecol. 2011 Nov; 118(5):1081-9. PMID: 22015876.
    View in: PubMed
  7. Iverson RE, Heffner LJ. Patient safety series: obstetric safety improvement and its reflection in reserved claims. Am J Obstet Gynecol. 2011 Nov; 205(5):398-401. PMID: 21531371.
    View in: PubMed
  8. Riley LE, Celi AC, Onderdonk AB, Roberts DJ, Johnson LC, Tsen LC, Leffert L, Pian-Smith MC, Heffner LJ, Haas ST, Lieberman ES. Association of epidural-related fever and noninfectious inflammation in term labor. Obstet Gynecol. 2011 Mar; 117(3):588-95. PMID: 21343762.
    View in: PubMed
  9. Wise LA, Palmer JR, Heffner LJ, Rosenberg L. Prepregnancy body size, gestational weight gain, and risk of preterm birth in African-American women. Epidemiology. 2010 Mar; 21(2):243-52. PMID: 20124904.
    View in: PubMed
  10. Declercq E, Barger M, Cabral HJ, Evans SR, Kotelchuck M, Simon C, Weiss J, Heffner LJ. Maternal outcomes associated with planned primary cesarean births compared with planned vaginal births. Obstet Gynecol. 2007 Mar; 109(3):669-77. PMID: 17329519.
    View in: PubMed
  11. Heffner LJ. How much does parity matter? Obstet Gynecol. 2005 Sep; 106(3):444-5. PMID: 16135571.
    View in: PubMed
  12. Heffner LJ. Advanced maternal age--how old is too old? N Engl J Med. 2004 Nov 4; 351(19):1927-9. PMID: 15525717.
    View in: PubMed
  13. Fretts RC, Elkin EB, Myers ER, Heffner LJ. Should older women have antepartum testing to prevent unexplained stillbirth? Obstet Gynecol. 2004 Jul; 104(1):56-64. PMID: 15229001.
    View in: PubMed
  14. Zelop C, Heffner LJ. The downside of cesarean delivery: short- and long-term complications. Clin Obstet Gynecol. 2004 Jun; 47(2):386-93. PMID: 15166862.
    View in: PubMed
  15. Bartlett JM, Wypij D, Bellinger DC, Rappaport LA, Heffner LJ, Jonas RA, Newburger JW. Effect of prenatal diagnosis on outcomes in D-transposition of the great arteries. Pediatrics. 2004 Apr; 113(4):e335-40. PMID: 15060264.
    View in: PubMed
  16. Heffner LJ, Elkin E, Fretts RC. Impact of labor induction, gestational age, and maternal age on cesarean delivery rates. Obstet Gynecol. 2003 Aug; 102(2):287-93. PMID: 12907101.
    View in: PubMed
  17. Ponkey SE, Cohen AP, Heffner LJ, Lieberman E. Persistent fetal occiput posterior position: obstetric outcomes. Obstet Gynecol. 2003 May; 101(5 Pt 1):915-20. PMID: 12738150.
    View in: PubMed
  18. McElrath TF, Norwitz ER, Lieberman ES, Heffner LJ. Perinatal outcome after preterm premature rupture of membranes with in situ cervical cerclage. Am J Obstet Gynecol. 2002 Nov; 187(5):1147-52. PMID: 12439493.
    View in: PubMed
  19. Heffner LJ. Uterine rupture among women with a prior cesarean delivery. N Engl J Med. 2002 Jan 10; 346(2):134-7. PMID: 11784884.
    View in: PubMed
  20. Richardson DK, Heffner LJ. Fetal-lung maturity: tests mature, interpretation not. Lancet. 2001 Sep 1; 358(9283):684-6. PMID: 11551571.
    View in: PubMed
  21. Lieberman E, Eichenwald E, Mathur G, Richardson D, Heffner L, Cohen A. Intrapartum fever and unexplained seizures in term infants. Pediatrics. 2000 Nov; 106(5):983-8. PMID: 11061764.
    View in: PubMed
  22. McElrath TF, Norwitz ER, Lieberman ES, Heffner LJ. Management of cervical cerclage and preterm premature rupture of the membranes: should the stitch be removed? Am J Obstet Gynecol. 2000 Oct; 183(4):840-6. PMID: 11035323.
    View in: PubMed
  23. Kumari M, Heffner LJ. The effects of L-arginine on the release of prolactin from decidual explants in vitro. Am J Obstet Gynecol. 2000 Mar; 182(3):497-502. PMID: 10739497.
    View in: PubMed
  24. Lieberman E, Lang J, Richardson DK, Frigoletto FD, Heffner LJ, Cohen A. Intrapartum maternal fever and neonatal outcome. Pediatrics. 2000 Jan; 105(1 Pt 1):8-13. PMID: 10617697.
    View in: PubMed
  25. Heffner LJ, Kumari M, Benoit LA. Secretion of the vasoactive peptides, endothelin, and parathyroid hormone-related peptide, by decidual explants from pregnancies complicated by intrauterine growth restriction. J Soc Gynecol Investig. 1999 Sep-Oct; 6(5):273-7. PMID: 10554767.
    View in: PubMed
  26. Lieberman E, Lang JM, Heffner LJ, Cohen A. Assessing the role of case mix in cesarean delivery rates. Obstet Gynecol. 1998 Jul; 92(1):1-7. PMID: 9649082.
    View in: PubMed
  27. Benson CB, Doubilet PM, Acker D, Heffner LJ. Multifetal pregnancy reduction of both fetuses of a monochorionic pair by intrathoracic potassium chloride injection of one fetus. J Ultrasound Med. 1998 Jul; 17(7):447-9. PMID: 9669303.
    View in: PubMed
  28. Heffner LJ, Benoit LA, Clemmons DR, Copeland KC. The secretion of insulin-like growth factor I, prolactin and insulin-like growth factor binding protein 1 by the decidua as predictors of human fetal growth. Growth Horm IGF Res. 1998 Feb; 8(1):33-8. PMID: 10990442.
    View in: PubMed
  29. Zelop CM, Richardson DK, Heffner LJ. Outcomes of severely abnormal umbilical artery doppler velocimetry in structurally normal singleton fetuses. Obstet Gynecol. 1996 Mar; 87(3):434-8. PMID: 8598969.
    View in: PubMed
  30. Doss BJ, Greene MF, Hill J, Heffner LJ, Bieber FR, Genest DR. Massive chronic intervillositis associated with recurrent abortions. Hum Pathol. 1995 Nov; 26(11):1245-51. PMID: 7590700.
    View in: PubMed
  31. Heffner LJ, Markoff E, Yuan RW, Lee DW. Glycosylated human prolactin: detection by immunoblotting of biological fluids is confounded by antisera crossreactivity with immunoglobulins. Biochem Biophys Res Commun. 1995 Jul 6; 212(1):48-55. PMID: 7612017.
    View in: PubMed
  32. Sherman CB, Tollerud DJ, Heffner LJ, Speizer FE, Weiss ST. Airway responsiveness in young black and white women. Am Rev Respir Dis. 1993 Jul; 148(1):98-102. PMID: 8317822.
    View in: PubMed
  33. Nowak RA, Rein MS, Heffner LJ, Friedman AJ, Tashjian AH. Production of prolactin by smooth muscle cells cultured from human uterine fibroid tumors. J Clin Endocrinol Metab. 1993 May; 76(5):1308-13. PMID: 8496322.
    View in: PubMed
  34. Heffner LJ, Sherman CB, Speizer FE, Weiss ST. Clinical and environmental predictors of preterm labor. Obstet Gynecol. 1993 May; 81(5 ( Pt 1)):750-7. PMID: 8469467.
    View in: PubMed
  35. Heffner LJ, Bromley BS, Copeland KC. Secretion of prolactin and insulin-like growth factor I by decidual explant cultures from pregnancies complicated by intrauterine growth retardation. Am J Obstet Gynecol. 1992 Nov; 167(5):1431-6. PMID: 1443001.
    View in: PubMed
  36. Rein MS, Friedman AJ, Pandian MR, Heffner LJ. The secretion of insulin-like growth factors I and II by explant cultures of fibroids and myometrium from women treated with a gonadotropin-releasing hormone agonist. Obstet Gynecol. 1990 Sep; 76(3 Pt 1):388-94. PMID: 2116610.
    View in: PubMed
  37. Rein MS, Friedman AJ, Heffner LJ. Decreased prolactin secretion by explant cultures of fibroids from women treated with a gonadotropin-releasing hormone agonist. J Clin Endocrinol Metab. 1990 Jun; 70(6):1554-8. PMID: 2112150.
    View in: PubMed
  38. Heffner LJ. Angiographic embolization. Am J Obstet Gynecol. 1990 May; 162(5):1345-6. PMID: 2339740.
    View in: PubMed
  39. Heffner LJ, Gramates LS, Yuan RW. A glycosylated prolactin species is covalently bound to immunoglobulin in human amniotic fluid. Biochem Biophys Res Commun. 1989 Nov 30; 165(1):299-305. PMID: 2590229.
    View in: PubMed
  40. Greene MF, Hare JW, Krache M, Phillippe M, Barss VA, Saltzman DH, Nadel A, Younger MD, Heffner L, Scherl JE. Prematurity among insulin-requiring diabetic gravid women. Am J Obstet Gynecol. 1989 Jul; 161(1):106-11. PMID: 2665491.
    View in: PubMed
  41. Benacerraf BR, Greene MF, Saltzman DH, Barss VA, Penso CA, Nadel AS, Heffner LJ, Stryker JM, Sandstrom MM, Frigoletto FD. Early amniocentesis for prenatal cytogenetic evaluation. Radiology. 1988 Dec; 169(3):709-10. PMID: 3055033.
    View in: PubMed
  42. Barss VA, Benacerraf BR, Frigoletto FD, Greene MF, Penso C, Saltzman DH, Nadel A, Heffner LJ, Scherl JE, Doubilet PM. Management of isoimmunized pregnancy by use of intravascular techniques. Am J Obstet Gynecol. 1988 Oct; 159(4):932-7. PMID: 3177548.
    View in: PubMed
  43. Heffner LJ, Iddenden DA, Lyttle CR. Electrophoretic analyses of secreted human endometrial proteins: identification and characterization of luteal phase prolactin. J Clin Endocrinol Metab. 1986 Jun; 62(6):1288-95. PMID: 3700587.
    View in: PubMed
  44. Heffner LJ, Mennuti MT, Rudoff JC, McLean GK. Primary management of postpartum vulvovaginal hematomas by angiographic embolization. Am J Perinatol. 1985 Jul; 2(3):204-7. PMID: 4015768.
    View in: PubMed
  45. Heffner LJ, Storey BT. Cold lability of mouse sperm binding to zona pellucida. J Exp Zool. 1982 Feb 1; 219(2):155-6. PMID: 7061969.
    View in: PubMed
  46. Heffner LJ, Storey BT. The role of calcium in maintaining motility in mouse spermatozoa. J Exp Zool. 1981 Dec; 218(3):427-34. PMID: 7338726.
    View in: PubMed
  47. Heffner LJ, Saling PM, Storey BT. Separation of calcium effects on motility and zona binding ability in mouse spermatozoa. J Exp Zool. 1980 Apr; 212(1):53-9. PMID: 6893338.
    View in: PubMed
  48. Heffner LJ, van Tienhoven A. Effects of neonatal ovariectomy upon 3H-estradiol uptake by target tissues of androgen-sterilized female rats. Neuroendocrinology. 1979; 29(4):327-46. PMID: 514457.
    View in: PubMed
  49. Heffner LJ. 3H-Estradiol uptake and retention by target tissues of light-sterilized female rats. Neuroendocrinology. 1976; 20(4):319-27. PMID: 987553.
    View in: PubMed
  50. Heffner LJ, Van Tienhoven A. Effects of progesterone on uptake and retention of 3 H-testosterone in the neonatal female rate. Neuroendocrinology. 1973; 12(2):129-41. PMID: 4717623.
    View in: PubMed
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