Karl J. Karlson, MD
Emeritus Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Surgery
Cardiothoracic Surgery

MD, Brown University School of Medicine
MMS/MMSc, Brown University
AB, Brown University



As a clinical cardiac surgeon, I am frequently confronted with the problems of revascularization of the ischemic heart. Coronary artery bypass grafting is often employed to deliver new blood supply to the myocardium, but occasionally the anastomoses fail because of the development of neointimal hyperplasia and fibrosis where vessel connections are constructed. Using nanotechnology to deliver agents to the site of the anastomoses could be a game changer in terms of graft patency.

Transmyocardial laser revascularization of the heart has been shown to trigger neovascularization in underperfused regions of the myocardium not amenable to standard revascularization. The prospect of using nanotechnology to deliver growth factor or other agents in a targeted fashion to the area of the laser channels may help to achieve a quantum increase in the benefit realized from the laser surgery.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Chief
Boston Medical Center
Cardiac Surgery




Flipped Biomedical Grand Rounds: Creating a Clinical Immersion Classroom
06/04/2018 - 03/31/2024 (Multi-PI)
PI: Karl J. Karlson, MD
NIH/National Institute of Biomedical Imaging & Bioengineering
5R25EB025788-05



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Dobrilovic N, Karlson K, Raman J, Soukas P, Sadiq I, Vognar L, Singh A. Left Bronchial Compression After Endovascular Repair of Contained Rupture of Descending Thoracic Aortic Dissection. Innovations (Phila). 2024; 19(1):92-93. PMID: 38284402
     
  2. Wang Y, Yin K, Datar Y, Mohnot J, Nodoushani AY, Zhan Y, Karlson KJ, Edwards NM, Reardon MJ, Dobrilovic N. Aortic Dissection During Pregnancy and Puerperium: Contemporary Incidence and Outcomes in the United States. J Am Heart Assoc. 2023 May 02; 12(9):e028436.View Related Profiles. PMID: 37119066; PMCID: PMC10227208; DOI: 10.1161/JAHA.122.028436;
     
  3. Nodoushani AY, Wang Y, Datar Y, Mohnot J, Karlson KJ, Edwards NM, Yin K, Dobrilovic N. Association of Intravenous Drug Use and Length of Stay Following Infective Endocarditis. J Surg Res. 2023 Feb; 282:239-245.View Related Profiles. PMID: 36332302; DOI: 10.1016/j.jss.2022.10.004;
     
  4. Datar Y, Yin K, Wang Y, Lawrence KW, Awtry EH, Cervantes-Arslanian AM, Kimmel SD, Fagan MA, Weinstein ZM, Karlson KJ, McAneny DB, Edwards NM, Dobrilovic N. Surgical outcomes of pulmonary valve infective endocarditis: A US population-based analysis. Int J Cardiol. 2022 Aug 15; 361:50-54.View Related Profiles. PMID: 35597492; DOI: 10.1016/j.ijcard.2022.05.033;
     
  5. Lawrence KW, Yin K, Connelly HL, Datar Y, Brydges H, Balasubramaniyan R, Karlson KJ, Edwards NM, Dobrilovic N. Sex-based outcomes in surgical repair of acute type A aortic dissection: A meta-analysis and meta-regression. J Thorac Cardiovasc Surg. 2024 Jan; 167(1):76-85.e13.View Related Profiles. PMID: 35331557
     
  6. Brydges H, Yin K, Balasubramaniyan R, Lawrence KW, Luo R, Karlson KJ, McAneny DB, Edwards NM, Reardon MJ, Dobrilovic N. Primary Pericardial Mesothelioma: A Population-Based Propensity Score-Matched Analysis. Semin Thorac Cardiovasc Surg. 2022 Autumn; 34(3):1113-1119.View Related Profiles. PMID: 34320396
     
  7. Yin K, March RJ, Hoopes CW, Balk RA, Raman J, Lateef OB, Tiwari A, Bak E, Karlson KJ, Edwards NM, Dobrilovic N. Extracorporeal membrane oxygenation in the management of granulomatosis with polyangiitis. J Card Surg. 2021 Feb; 36(2):743-747.View Related Profiles. PMID: 33350513
     
  8. Yin K, Brydges H, Lawrence KW, Wei Y, Karlson KJ, McAneny DB, Edwards NM, Reardon MJ, Dobrilovic N. Primary cardiac lymphoma. J Thorac Cardiovasc Surg. 2022 Aug; 164(2):573-580.e1.View Related Profiles. PMID: 33158567
     
  9. Yin K, Luo R, Wei Y, Wang F, Zhang Y, Karlson KJ, Zhang Z, Reardon MJ, Dobrilovic N. Survival outcomes in patients with primary cardiac sarcoma in the United States. J Thorac Cardiovasc Surg. 2021 07; 162(1):107-115.e2.View Related Profiles. PMID: 32111430
     
  10. Lazar HL, Ketchedjian A, Haime M, Karlson K, Cabral H. Topical vancomycin in combination with perioperative antibiotics and tight glycemic control helps to eliminate sternal wound infections. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):1035-8; 1038-40.View Related Profiles. PMID: 25129595; DOI: 10.1016/j.jtcvs.2014.06.045;
     
Showing 10 of 20 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 20 publications over 12 distinct years, with a maximum of 3 publications in 1992 and 1994 and 2020 and 2022

YearPublications
19851
19871
19881
19911
19923
19943
20141
20203
20211
20223
20231
20241


Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Project Mentor
Contact for Mentoring:

88 E. Newton St Newton Pavilion
Boston MA 02118
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