Timothy Mark O'Shea, PhD
Assistant Professor
Boston University College of Engineering
Dept of Biomedical Engineering

PhD, Massachusetts Institute of Technology
ME/MEng, Queensland University of Technology





Promoting astroglial maturation of NPC grafts in SCI lesion cores using immunomodulatory hydrogels
07/31/2021 - 07/30/2023 (PI)
Craig H. Neilsen Foundation


Promoting glia-based repair in spinal cord injury
06/01/2021 - 05/31/2022 (PI)
Bryon Riesch Paralysis Foundation




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. O’Shea, T.M., Wollenberg, A.L., Kim, J.H., Ao, Y. Deming, T.J. and Sofroniew M.V. Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions. Nature Communications. 2020; 11:6203.
  2. *Garrett, M.C., O’Shea, T.M., Wollenberg, A.L., Bernstein, A.M., Hung, D., Staarman, B., Soto, H., Deming, T.J., Sofroniew M.V., and Kornblum, H.I. Injectable diblock copolypeptide hydrogel provides platform to maintain high local concentrations of taxol and local tumor control. Plos One. 2020; 15 (7):e0219632.
  3. *Anderson, M.A., *O’Shea, T.M., Burda, J.E., Ao, Y., Barlatey, S.L., Bernstein A.M., Kim, J.H., James, N.D., Rogers, A., Kato, B., Wollenberg, A.L., Kawaguchi, R., Coppola, G., Wang, C., Deming, T.J., He, Z., Courtine, G., and Sofroniew M.V. Required growth facilitators propel axon regeneration across complete spinal cord injury. Nature. 2018; 561:396–400.
  4. Wollenberg, A.L. *O’Shea, T.M., Kim, J., Sofroniew M.V., and Deming, T.J. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. Biomaterials. 2018; 178:527-545.
  5. Sun, Y., Wollenberg, A.L., O’Shea, T.M., Cui, Y., Zhou, Z.H., Sofroniew M.V. and Deming, T.J. Conformation directed formation of self-healing diblock copolypeptide hydrogels via polyion complexation. Journal of American Chemical Society. 2017; 139(42):15114-15121.
  6. Martinez-Moreno, M., O’Shea, T.M., Zepecki, J.P., Olaru, A., Ness, J.K., Langer, R. and Tapinos, N. Regulation of peripheral myelination through transcriptional buffering of Egr2 by an antisense long noncoding RNA. Cell Reports. 2017; 20(8):1950-1963.
  7. O’Shea, T.M., Burda, J. E., and Sofroniew M. V. Cell biology of spinal cord injury and repair. Journal of Clinical Investigation. 2017; 127(9):3259-3270.
  8. O'Shea T.M., Wollenberg A.L., Bernstein A.M., Sarte D.B., Deming T.J., and Sofroniew M.V. Smart Materials for Central Nervous System Cell Delivery and Tissue Engineering. Royal Society of Chemistry. 2017; Chapter 19:529-557.
  9. Slotkin, J. R., Pritchard C. D., Luque B., Ye J., Layer R. T., Lawrence M. S., O'Shea T. M., Roy R.R., Zhong H., Vollenweider I., Edgerton V. R., Courtine G., Woodard E. J., and Langer, R. Biodegradable scaffolds promote tissue remodeling and functional improvement in non-human primates with acute spinal cord injury. Biomaterials. 2017; 123 : 63-76.
  10. Ren, Y., Ao Y., O’Shea T. M., Burda J. E., Bernstein A. M., Brumm A. J., Muthusamy N., Ghashghaei H. T., Carmichael S. T., Cheng L. and Sofroniew M. V. Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. Scientific Reports. 2017; 7:7: 41122.
Showing 10 of 16 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 16 publications over 7 distinct years, with a maximum of 6 publications in 2017

YearPublications
20112
20141
20151
20162
20176
20182
20202


2019 Wings for Life Spinal Cord Foundation Postdoctoral Fellowship
2018 American Australian Association Keith Murdoch Scholarship
2018 Paralyzed Veterans of America (PVA) Research Foundation Fellowship
2016 Craig H Neilsen Postdoctoral Fellowship in Translational Spinal Cord Injury Research
2015 MISTI Global Seed Fund Student Award for research collaboration with Ben Gurion University, Israel
2015 HST Martha Gray Prize for Excellence in Research
2013 Langer Summit on Neurotrauma Prize
2012 HST Idea2 Fellowship for novel and inspiring ideas in medical research
2012 Society of Chemical Industry Perkins Student Scholarship
2010 Ohio State University: Spinal Cord Injury Training Program
2009 Harvard-MIT Division of Health Sciences and Technology Fellowship
Contact for Mentoring:

44 Cummington St, Boston MA 02215
Boston MA 02215
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