Santiago Rodriguez Ospina, PhD
Postdoctoral Associate (previously held)
Boston University Chobanian & Avedisian School of Medicine
Dermatology




Dr. Rodriguez Ospina is a biochemist focused in cellular and neurobiology with experience in recombinant and mouse models. Skilled in developing and driving protein production (EPL), biochemical (ThT, FP, enzymatic) assays, peptide synthesis and purification (HPLC, MALDI), and cellular and animal (FRET, animal behavior) studies for characterization and elucidation of protein-protein interactions in chaperone biology, oncology, and neurobiology.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Viennet T, Rodriguez Ospina S, Lu Y, Cui A, Arthanari H, Dempsey DR. Chemical and structural approaches to investigate PTEN function and regulation. Methods Enzymol. 2023; 682:289-318.View Related Profiles. PMID: 36948705; PMCID: PMC10037535; DOI: 10.1016/bs.mie.2022.09.007;
     
  2. Viennet T, Rodriguez Ospina S, Lu Y, Cui A, Arthanari H, Dempsey DR. Chemical and structural approaches to investigate PTEN function and regulation. Methods Enzymol. 2023; 682:289-318.View Related Profiles. PMID: 36948705; PMCID: PMC10037535; DOI: 10.1016/bs.mie.2022.09.007;
     
  3. Hill SE, Esquivel AR, Ospina SR, Rahal LM, Dickey CA, Blair LJ. Chaperoning activity of the cyclophilin family prevents tau aggregation. Protein Sci. 2022 Nov; 31(11):e4448. PMID: 36305768; PMCID: PMC9597375; DOI: 10.1002/pro.4448;
     
  4. Criado-Marrero M, Blazier DM, Gould LA, Gebru NT, Rodriguez Ospina S, Armendariz DS, Darling AL, Beaulieu-Abdelahad D, Blair LJ. Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice. Sci Rep. 2022 May 05; 12(1):7372. PMID: 35513476; PMCID: PMC9072347; DOI: 10.1038/s41598-022-11025-x;
     
  5. Rodriguez Ospina S, Blazier DM, Criado-Marrero M, Gould LA, Gebru NT, Beaulieu-Abdelahad D, Wang X, Remily-Wood E, Chaput D, Stevens S, Uversky VN, Bickford PC, Dickey CA, Blair LJ. Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain. Int J Mol Sci. 2022 Jan 13; 23(2). PMID: 35055033; PMCID: PMC8775832; DOI: 10.3390/ijms23020851;
     
  6. Baker JD, Ozsan I, Rodriguez Ospina S, Gulick D, Blair LJ. Hsp90 Heterocomplexes Regulate Steroid Hormone Receptors: From Stress Response to Psychiatric Disease. Int J Mol Sci. 2018 Dec 25; 20(1). PMID: 30585227; PMCID: PMC6337637; DOI: 10.3390/ijms20010079;
     
  7. Dempsey DR, Nichols DA, Battistini MR, Pemberton O, Ospina SR, Zhang X, Carpenter AM, O'Flynn BG, Leahy JW, Kanwar A, Lewandowski EM, Chen Y, Merkler DJ. Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine. Sci Rep. 2017 10 18; 7(1):13432.View Related Profiles. PMID: 29044148; PMCID: PMC5647378; DOI: 10.1038/s41598-017-13669-6;
     
  8. Dempsey DR, Carpenter AM, Ospina SR, Merkler DJ. Probing the chemical mechanism and critical regulatory amino acid residues of Drosophila melanogaster arylalkylamine N-acyltransferase like 2. Insect Biochem Mol Biol. 2015 Nov; 66:1-12.View Related Profiles. PMID: 26476413; PMCID: PMC4663176; DOI: 10.1016/j.ibmb.2015.10.003;
     
  9. Dempsey DR, Bond JD, Carpenter AM, Rodriguez Ospina S, Merkler DJ. Expression, purification, and characterization of mouse glycine N-acyltransferase in Escherichia coli. Protein Expr Purif. 2014 May; 97:23-8.View Related Profiles. PMID: 24576660; PMCID: PMC3985065; DOI: 10.1016/j.pep.2014.02.007;
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 5 distinct years, with a maximum of 4 publications in 2022

YearPublications
20141
20151
20171
20181
20224


2021 The American Society for Neural Therapy and Repair: Travel Fellowship for The American Society for Neural Therapy and Repair
2020 USF Health Neuroscience Institute, Byrd Alzheimer’s Center: Dorothy Benjamin Graduate Fellowship in Alzheimer's Disease Research
2014 University of South Florida: Chem-SEEDS Summer Research Fellowship
2014 Enzyme Structure and Function: Travel Fellowship for 36th Steenbock Symposium
2014 University of South Florida: Travel Fellowship for SERMACS
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