Ronald J. Killiany, PhD
Associate Professor
Boston University School of Medicine
Dept of Anatomy & Neurobiology

PhD, Northeastern University
MA, University of Hartford




The underlying theme of my research has been to explore structure – function relationships in the brain. To this end, my work has focused on uncovering the morphological changes in the brain that are responsible for the cognitive decline seen in aging and disease processes. In initial studies, I used developmental techniques to examine specific structure-function relationships in the memory system of non-human primates. I continued on to conduct studies of normal aging and cerebrovascular disease. In this work I have focused on characterize the cognitive changes taking place in non-human primate models. As my interests in studying the brain grew, I become involved in structural Magnetic Resonance Imaging (MRI) studies of normal aging and disorders such as Alzheimer’s disease. In this work I have been quantifying volumetric changes taking place in the brain in the course of the disease processes. This work continues to evolve and has changed focus somewhat in the recent years to include studies aimed at exploring the value of MRI in predicting which subjects will progress to develop cognitive decline and Alzheimer’s disease and which will remain cognitively stable.

Associate Professor
Boston University School of Public Health
Environmental Health


Associate Professor
Boston University School of Medicine
Neurology


Associate Professor
Boston University School of Medicine
Radiology
Body Imaging

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



2011 NeuroImage Award for Top-5 cited articles between 2006 & 2010
1993 Massachusetts Neuropsychological Society: Annual Award
1991 American Psychological Association: Dissertation Award


Clarifying the Role Played by Microglia and Astrocyte Activation in Veterans with Gulf War Illness Using Positron Emission Tomography (PET)
09/30/2019 - 09/29/2021 (PI)
Department of Defense/Army Medical Research Acquisition Activity


Vielight Neuro RX Gamma Photobiomodulation Device for Moderate to Severe Alzheimer's Disease
04/30/2019 - 04/30/2021 (PI)
Vielight Inc.


Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3)
09/15/2016 - 07/31/2020 (Subcontract PI)
University of Southern California NIH NIA
2U19AG024904-11

ADNI-DOD-TAU, Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder and Alzheimer's Disease on Brain Tau in Vietnam Veterans using ADNI
09/22/2016 - 09/21/2019 (Subcontract PI)
University of Southern California DOD Army Med Resrch


Human Neurobiology Laboratory Support Contract with Pfizer
01/01/2014 - 12/31/2018 (SP Co-PI of Sub-Project / SP)
PI: Kevin C. Thomas, PhD
Pfizer, Inc.


Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)
08/24/2015 - 03/31/2018 (Subcontract PI)
University of Southern California NIH NIA
5U01AG024904-10

Neurobiological Consequences of Hypertension and Age
03/01/2000 - 02/28/2010 (Co-PI)
NIH/National Institute on Aging
5 R37 AG17609 10

Age-Related Changes of Cognition in Health and Disease
08/01/2002 - 07/31/2007 (PI)
Massachusetts General Hospital NIH NIA

A Primate Model of Hypertensive Cerebrovascular
09/30/2002 - 08/31/2004 (PI)
NIH/National Institute on Aging
1 R03 AG21315 01



Title


Yr Title Project-Sub Proj Pubs
2013 Whole Animal Imaging Core 3UC7AI070088-05S3-6801 1
2012 Whole Animal Imaging Core 3UC7AI070088-05S2-7841 1
2011 Whole Animal Imaging Core 3UC7AI070088-05S1-7216 1
2009 3T quasar dual MRI scanner for multimodal and molecular imaging 1S10RR025035-01
2002 Primate Model of Hypertensive Cerebrovascular Disease 1R03AG021315-01
2002 MAGNETIC RESONANCE IMAGING (MRI) 2P01AG004953-19-6 107

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Sugarman MA, Zetterberg H, Blennow K, Tripodis Y, McKee AC, Stein TD, Martin B, Palmisano JN, Steinberg EG, Simkin I, Budson AE, Killiany R, O'Connor MK, Au R, Qiu WWQ, Goldstein LE, Kowall NW, Mez J, Stern RA, Alosco ML. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiol Aging. 2020 Oct; 94:60-70.View Related Profiles. PMID: 32585491; DOI: 10.1016/j.neurobiolaging.2020.05.011;
     
  2. Zajac L, Koo BB, Tripodis Y, Mian A, Steinberg E, Mez J, Alosco ML, Cervantes-Arslanian A, Stern R, Killiany R. Hippocampal Resting-State Functional Connectivity Patterns are More Closely Associated with Severity of Subjective Memory Decline than Whole Hippocampal and Subfield Volumes. Cereb Cortex Commun. 2020; 1(1):tgaa019.View Related Profiles. PMID: 32905008
     
  3. Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy. JAMA Neurol. 2019 Aug 05.View Related Profiles. PMID: 31380975; DOI: 10.1001/jamaneurol.2019.2244;
     
  4. Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML. Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set. Alzheimers Res Ther. 2019 07 27; 11(1):64.View Related Profiles. PMID: 31351489; DOI: 10.1186/s13195-019-0521-0;
     
  5. Kubicki M, Baxi M, Pasternak O, Tang Y, Karmacharya S, Chunga N, Lyall AE, Rathi Y, Eckbo R, Bouix S, Mortazavi F, Papadimitriou G, Shenton ME, Westin CF, Killiany R, Makris N, Rosene DL. Lifespan Trajectories of White Matter Changes in Rhesus Monkeys. Cereb Cortex. 2019 04 01; 29(4):1584-1593.View Related Profiles. PMID: 29701751
     
  6. Zajac L, Burte H, Taylor HA, Killiany R. Self-reported navigation ability is associated with optic flow-sensitive regions' functional connectivity patterns during visual path integration. Brain Behav. 2019 04; 9(4):e01236. PMID: 30884216
     
  7. Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia. Alzheimers Dement. 2019 05; 15(5):686-698.View Related Profiles. PMID: 30852157; DOI: 10.1016/j.jalz.2018.12.015;
     
  8. Janulewicz P, Krengel M, Quinn E, Heeren T, Toomey R, Killiany R, Zundel C, Ajama J, O'Callaghan J, Steele L, Klimas N, Sullivan K. The Multiple Hit Hypothesis for Gulf War Illness: Self-Reported Chemical/Biological Weapons Exposure and Mild Traumatic Brain Injury. Brain Sci. 2018 Nov 13; 8(11).View Related Profiles. PMID: 30428552; DOI: 10.3390/brainsci8110198;
     
  9. Taylor E, Huang N, Bodde J, Ellison A, Killiany R, Bachschmid MM, Hamilton J. MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits. J Transl Med. 2018 08 01; 16(1):215.View Related Profiles. PMID: 30068362
     
  10. Bauer CM, Cabral HJ, Killiany RJ. Multimodal Discrimination between Normal Aging, Mild Cognitive Impairment and Alzheimer's Disease and Prediction of Cognitive Decline. Diagnostics (Basel). 2018 Feb 06; 8(1).View Related Profiles. PMID: 29415470
     
Showing 10 of 109 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 109 publications over 27 distinct years, with a maximum of 10 publications in 2017

YearPublications
19931
19951
19961
19974
19981
19995
20001
20013
20024
20036
20042
20057
20066
20076
20086
20095
20107
20115
20124
20133
20144
20152
20164
201710
20184
20195
20202
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Aging
Cerebrovascular disease
Cognition
Data analysis
Dementia
Experimental Design
Magnetic Resonance Imaging
Memory
Neuropsychology
Statistics

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Education Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Google Map


Killiany's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Media Mentions
_
Co-Authors
_
Similar People
_
Same Department