Richard Goldstein, PhD
Boston University School of Medicine
Dept of Pediatrics
Infectious Diseases

PhD, University of Pennsylvania

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Richard Goldstein received his PhD in biophysical chemistry at the University of Pennsylvania. Shortly after he joined BUSM and Boston University School of Public Health as a professor of public health. He conducted extensive research with bacterial pathogens such as uropathogenic Eschericia coli that led to an appointment in the Division of adult Infectious Diseases in 1992. Several years later he was appointed Professor of Pediatrics in the Division of Pediatric Infectious Diseases. He has received numerous honors and awards and has served on many scientific committees and advisory groups. Goldstein has several patents and has authored various papers since the start of his career.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Boston Medical Center

2009-2013 The Hartwell Foundation: Hartwell Biomedical Investigator

A Vaccine Against Streptococcus Pneumoniae Based on Phylogenically Identified Highly Conserved Bacterial Surface Proteins
04/01/2010 - 03/31/2014 (PI)
The Hartwell Foundation

NTHi LPS: Virulence Factor and Vaccine Candidate
08/01/2003 - 07/31/2008 (PI)
NIH/National Institute on Deafness & Communication Disorders
5 R01 DC05855 04

Recombination-quiescent genes & phylogenic validation of encoded vaccine targets
07/01/2010 - 06/30/2013 (PI)
5R21 AI081687-02

Role of Sialylated LPS in H. Influenza
04/25/2002 - 03/31/2004 (PI)
1 R21 DC 05564-02 (A)

Vaccination & The Evolutionary
02/01/2001 - 07/31/2003 (PI)
Harvard School of Public Health NIH-NIAID
1 R01 AI48935-03

Rational Strategy For Vaccine
05/01/1999 - 06/30/2003 (PI)
Cystic Fibrosis Fdtn

Microbial Population Strategy
02/01/2001 - 01/31/2003 (PI)
1 R01 DC04583-01A1 (A)

Virulence Genetics Of Cf Assoc
07/10/1996 - 05/31/2000 (PI)
5 R01 DK50838-05

Yr Title Project-Sub Proj Pubs
2011 Recombination-quiescent genes &phylogenic validation of encoded vaccine targets 5R21AI081687-02 1
2010 Recombination-quiescent genes &phylogenic validation of encoded vaccine targets 1R21AI081687-01A1 1
2006 NTHi LPS: virulence factor and vaccine candidate 5R01DC005855-04 7
2005 NTHi LPS: virulence factor and vaccine candidate 5R01DC005855-03 7
2004 NTHi LPS: virulence factor and vaccine candidate 5R01DC005855-02 7
2003 NTHi LPS: virulence factor and vaccine candidate 1R01DC005855-01A1 7
2003 Role of sialylated LPS in H. influenzae otitis media 5R21DC005564-02 4
2002 Role of sialylated LPS in H. influenzae otitis media 1R21DC005564-01 4
Showing 10 of 20 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Lundström SL, Li J, Månsson M, Figueira M, Leroy M, Goldstein R, Hood DW, Moxon ER, Richards JC, Schweda EK. Application of capillary electrophoresis mass spectrometry and liquid chromatography multiple-step tandem electrospray mass spectrometry to profile glycoform expression during Haemophilus influenzae pathogenesis in the chinchilla model of experimental otitis media. Infect Immun. 2008 Jul; 76(7):3255-67.View Related Profiles. PMID: 18458064; PMCID: PMC2446737; DOI: 10.1128/IAI.01710-07;.
  2. Bouchet V, Huot H, Goldstein R. Molecular genetic basis of ribotyping. Clin Microbiol Rev. 2008 Apr; 21(2):262-73, table of contents.View Related Profiles. PMID: 18400796; PMCID: PMC2292578; DOI: 10.1128/CMR.00026-07;.
  3. Lipsitch M, O'Neill K, Cordy D, Bugalter B, Trzcinski K, Thompson CM, Goldstein R, Pelton S, Huot H, Bouchet V, Reid R, Santosham M, O'Brien KL. Strain characteristics of Streptococcus pneumoniae carriage and invasive disease isolates during a cluster-randomized clinical trial of the 7-valent pneumococcal conjugate vaccine. J Infect Dis. 2007 Oct 15; 196(8):1221-7.View Related Profiles. PMID: 17955441; PMCID: PMC3350793.
  4. Pelton SI, Huot H, Finkelstein JA, Bishop CJ, Hsu KK, Kellenberg J, Huang SS, Goldstein R, Hanage WP. Emergence of 19A as virulent and multidrug resistant Pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2007 Jun; 26(6):468-72.View Related Profiles. PMID: 17529860.
  5. Leroy M, Cabral H, Figueira M, Bouchet V, Huot H, Ram S, Pelton SI, Goldstein R. Multiple consecutive lavage samplings reveal greater burden of disease and provide direct access to the nontypeable Haemophilus influenzae biofilm in experimental otitis media. Infect Immun. 2007 Aug; 75(8):4158-72.View Related Profiles. PMID: 17517860; PMCID: PMC1952021.
  6. Hanage WP, Huang SS, Lipsitch M, Bishop CJ, Godoy D, Pelton SI, Goldstein R, Huot H, Finkelstein JA. Diversity and antibiotic resistance among nonvaccine serotypes of Streptococcus pneumoniae carriage isolates in the post-heptavalent conjugate vaccine era. J Infect Dis. 2007 Feb 1; 195(3):347-52.View Related Profiles. PMID: 17205472.
  7. Figueira MA, Ram S, Goldstein R, Hood DW, Moxon ER, Pelton SI. Role of complement in defense of the middle ear revealed by restoring the virulence of nontypeable Haemophilus influenzae siaB mutants. Infect Immun. 2007 Jan; 75(1):325-33.View Related Profiles. PMID: 17088344; PMCID: PMC1828410.
  8. Bouchet V, Hood DW, Li J, Brisson JR, Randle GA, Martin A, Li Z, Goldstein R, Schweda EK, Pelton SI, Richards JC, Moxon ER. Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8898-903.View Related Profiles. PMID: 12855765; PMCID: PMC166410.
  9. Cody AJ, Field D, Feil EJ, Stringer S, Deadman ME, Tsolaki AG, Gratz B, Bouchet V, Goldstein R, Hood DW, Moxon ER. High rates of recombination in otitis media isolates of non-typeable Haemophilus influenzae. Infect Genet Evol. 2003 May; 3(1):57-66.View Related Profiles. PMID: 12797973; PMCID: PMC2728426.
  10. Meats E, Feil EJ, Stringer S, Cody AJ, Goldstein R, Kroll JS, Popovic T, Spratt BG. Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J Clin Microbiol. 2003 Apr; 41(4):1623-36. PMID: 12682154; PMCID: PMC153921.
Showing 10 of 42 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 31 publications over 17 distinct years, with a maximum of 4 publications in 1990

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670 Albany St Biosquare III
Boston MA 02118
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