S. Reza Jafarzadeh, DVM, MPVM, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine

DVM, University of Tehran
MPVM, University of California, Davis
PhD, University of California, Davis

I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.

I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.

Boston University
Arthritis & Autoimmune Diseases Research Center

2020 Boston University Clinical and Translational Science Institute (BU-CTSI): Mini Sabbatical Award
2019 Rheumatology Research Foundation (RRF): Innovative Research Award
2018 Arthritis & Rheumatology: Editor’s Choice Article
2014 American College of Epidemiology (ACE): Travel Award
2013 American College of Epidemiology (ACE): Travel Award
2009-2010 University of California, Davis: Graduate Student Support Program (GSSP)
2007-2008 University of California, Davis: Epidemiology Graduate Group Fellowship

Dynamic Treatment Regimens of Physical Activity for Persons with Osteoarthritis
09/01/2019 - 07/31/2021 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

Effects of NSAIDs and non-NSAID Analgesics on Osteoarthritis Outcomes
09/01/2018 - 05/31/2021 (PI)
NIH/National Institute on Aging

Global Awards for Advancing Chronic Pain Research (ADVANCE) 2018 _ NSAIDs, COX2 inhibitors, and opioids long-term effects on knee osteoarthritis progression and joint replacement
11/19/2018 - 12/31/2020 (PI)
Pfizer, Inc.

Personalized dynamic regimens of physical activity for persons with knee osteoarthritis
07/01/2019 - 09/30/2019 (PI)
Rheumatology Research Foundation


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Felson D, Rabasa G, Jafarzadeh SR, Nevitt M, Lewis CE, Segal N, White DK. Factors associated with pain resolution in those with knee pain: the MOST study. Osteoarthritis Cartilage. 2021 Apr 24.View Related Profiles. PMID: 33901642
  2. McGrew KM, Garwe T, Jafarzadeh SR, Drevets DA, Zhao YD, Williams MB, Carabin H. Misclassification Error-Adjusted Prevalence of Injection Drug Use Among Infective Endocarditis Hospitalizations in the United States: A Serial Cross-Sectional Analysis of the 2007-2016 National Inpatient Sample. Am J Epidemiol. 2021 04 06; 190(4):588-599. PMID: 32997130
  3. Macri EM, Neogi T, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner JC, Lynch JA, Tolstykh I, Jafarzadeh SR, Stefanik JJ. Can MRI-defined osteoarthritis features explain anterior knee pain in individuals with, or at risk for, knee osteoarthritis? The MOST Study. Arthritis Care Res (Hoboken). 2021 Mar 25.View Related Profiles. PMID: 33768706
  4. Fawole HO, Felson DT, Frey-Law LA, Jafarzadeh SR, Dell'Isola A, Steultjens MP, Nevitt MC, Lewis CE, Riskowski JL, Chastin S. Is the association between physical activity and fatigue mediated by physical function or depressive symptoms in symptomatic knee osteoarthritis? The Multicenter Osteoarthritis Study. Scand J Rheumatol. 2021 Mar 20; 1-9.View Related Profiles. PMID: 33749506
  5. Sinha P, Jafarzadeh SR, Assoumou SA, Bielick CG, Carpenter B, Garg S, Harleen S, Neogi T, Nishio MJ, Sagar M, Sharp V, Kissin EY. The Effect of IL-6 Inhibitors on Mortality Among Hospitalized COVID-19 Patients: A Multicenter Study. J Infect Dis. 2021 02 24; 223(4):581-588.View Related Profiles. PMID: 33216906; PMCID: PMC7717300; DOI: 10.1093/infdis/jiaa717;
  6. Ghaemmaghami P, Ayatollahi SMT, Bagheri Z, Jafarzadeh SR. Covariate-adjusted Bayesian estimation of the performance of a continuous diagnostic test with a limit of detection in the absence of a reference standard: a simulation study. Communications in Statistics - Simulation and Computation. 2021. View Publication
  7. Bacon K, LaValley MP, Jafarzadeh SR, Felson D. Response to: 'Relation between cartilage loss and pain in knee osteoarthritis' by Wu et al and 'Changes in synovitis and bone marrow lesions may not mediate the effect of cartilage loss on joint pain in osteoarthritis' by Cashin et al. Ann Rheum Dis. 2020 Oct 07.View Related Profiles. PMID: 33028581
  8. Law ST, Jafarzadeh SR, Govender P, Sun X, Sanchorawala V, Kissin EY. Comparison of Ultrasound Features of Major Salivary Glands in Sarcoidosis, Amyloidosis, and Sjögren's Syndrome. Arthritis Care Res (Hoboken). 2020 10; 72(10):1466-1473.View Related Profiles. PMID: 31309727
  9. Grammatico-Guillon L, Jafarzadeh SR, Laurent E, Shea K, Pasco J, Astagneau P, Adams W, Pelton S. Gradual decline in outpatient antibiotic prescriptions in paediatrics: A data warehouse-based 11-year cohort study. Acta Paediatr. 2021 02; 110(2):611-617.View Related Profiles. PMID: 32573837
  10. Bacon K, LaValley MP, Jafarzadeh SR, Felson D. Does cartilage loss cause pain in osteoarthritis and if so, how much? Ann Rheum Dis. 2020 08; 79(8):1105-1110.View Related Profiles. PMID: 32381567
Showing 10 of 41 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 41 publications over 13 distinct years, with a maximum of 8 publications in 2018


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Bayesian Methods
Causal Inference
Diagnostic Tests Evaluation
Estimation of True Prevalence with Imperfect Tests
Machine Learning

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

650 Albany Street, Suite X200
Boston MA 02118
Google Map

(617) 638-5239 (fax)

Jafarzadeh's Networks
Click the "See All" links for more information and interactive visualizations
Similar People
Same Department