S. Reza Jafarzadeh, DVM, MPVM, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine

DVM, University of Tehran
MPVM, University of California, Davis
PhD, University of California, Davis

I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.

I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.

Boston University
Arthritis & Autoimmune Diseases Research Center

2020 Boston University Clinical and Translational Science Institute (BU-CTSI): Mini Sabbatical Award
2019 Rheumatology Research Foundation (RRF): Innovative Research Award
2018 Arthritis & Rheumatology: Editor’s Choice Article
2014 American College of Epidemiology (ACE): Travel Award
2013 American College of Epidemiology (ACE): Travel Award
2009-2010 University of California, Davis: Graduate Student Support Program (GSSP)
2007-2008 University of California, Davis: Epidemiology Graduate Group Fellowship

Dynamic Treatment Regimens of Physical Activity for Persons with Osteoarthritis
09/01/2019 - 07/31/2021 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

Personalized dynamic regimens of physical activity for persons with knee osteoarthritis
07/01/2019 - 06/30/2021 (PI)
Rheumatology Research Foundation

Global Awards for Advancing Chronic Pain Research (ADVANCE) 2018 _ NSAIDs, COX2 inhibitors, and opioids long-term effects on knee osteoarthritis progression and joint replacement
11/19/2018 - 12/31/2020 (PI)
Pfizer, Inc.

Effects of NSAIDs and non-NSAID Analgesics on Osteoarthritis Outcomes
09/01/2018 - 05/31/2020 (PI)
NIH/National Institute on Aging


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Grammatico-Guillon L, Jafarzadeh SR, Laurent E, Shea K, Pasco J, Astagneau P, Adams W, Pelton S. Gradual decline in outpatient antibiotic prescriptions in paediatrics: A data warehouse-based 11-year cohort study. Acta Paediatr. 2020 Jun 23.View Related Profiles. PMID: 32573837
  2. Bacon K, LaValley MP, Jafarzadeh SR, Felson D. Does cartilage loss cause pain in osteoarthritis and if so, how much? Ann Rheum Dis. 2020 08; 79(8):1105-1110.View Related Profiles. PMID: 32381567
  3. Kumar D, Link TM, Jafarzadeh SR, LaValley MP, Majumdar S, Souza RB. Quadriceps adiposity is associated with increase in lesions of the knee cartilage, meniscus, or bone marrow over 3-years. Arthritis Care Res (Hoboken). 2020 Apr 27.View Related Profiles. PMID: 32339414
  4. McGrew KM, Carabin H, Garwe T, Jafarzadeh SR, Williams MB, Zhao YD, Drevets DA. Validity of ICD-based algorithms to estimate the prevalence of injection drug use among infective endocarditis hospitalizations in the absence of a reference standard. Drug Alcohol Depend. 2020 Apr 01; 209:107906. PMID: 32145659
  5. Jafarzadeh SR, Neogi T, Stefanik JJ, Li JS, Guermazi A, Apovian CM, Felson DT. Mediating Role of Bone Marrow Lesions, Synovitis, Pain Sensitization, and Depressive Symptoms on Knee Pain Improvement Following Substantial Weight Loss. Arthritis Rheumatol. 2020 03; 72(3):420-427.View Related Profiles. PMID: 31562683
  6. McGrew KM, Homco JB, Garwe T, Dao HD, Williams MB, Drevets DA, Jafarzadeh SR, Zhao YD, Carabin H. Validity of International Classification of Diseases codes in identifying illicit drug use target conditions using medical record data as a reference standard: A systematic review. Drug Alcohol Depend. 2020 Mar 01; 208:107825. PMID: 31982637; DOI: 10.1016/j.drugalcdep.2019.107825;
  7. Law ST, Jafarzadeh SR, Govender P, Sun X, Sanchorawala V, Kissin EY. Comparison of Ultrasound Features of Major Salivary Glands in Sarcoidosis, Amyloidosis, and Sjögren's Syndrome. Arthritis Care Res (Hoboken). 2019 Jul 15.View Related Profiles. PMID: 31309727
  8. Grammatico-Guillon L, Shea K, Jafarzadeh SR, Camelo I, Maakaroun-Vermesse Z, Figueira M, Adams WG, Pelton S. Antibiotic Prescribing in Outpatient Children: A Cohort From a Clinical Data Warehouse. Clin Pediatr (Phila). 2019 06; 58(6):681-690.View Related Profiles. PMID: 30884973; DOI: 10.1177/0009922819834278;
  9. Dai Z, Jafarzadeh SR, Niu J, Felson DT, Jacques PF, Li S, Zhang Y. Body Mass Index Mediates the Association between Dietary Fiber and Symptomatic Knee Osteoarthritis in the Osteoarthritis Initiative and the Framingham Osteoarthritis Study. J Nutr. 2018 12 01; 148(12):1961-1967.View Related Profiles. PMID: 30517729
  10. Jafarzadeh SR, Felson DT. Reply. Arthritis Rheumatol. 2019 01; 71(1):175-176.View Related Profiles. PMID: 30251475
Showing 10 of 34 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 34 publications over 12 distinct years, with a maximum of 8 publications in 2018


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Bayesian Methods
Causal Inference
Diagnostic Tests Evaluation
Estimation of True Prevalence with Imperfect Tests
Machine Learning

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650 Albany Street, Suite X200
Boston MA 02118
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