S. Reza Jafarzadeh | Profiles RNS

S. Reza Jafarzadeh, DVM, MPVM, PhD

Assistant Professor

Boston University School of Medicine

Dept of Medicine

Rheumatology

DVM, University of Tehran
MPVM, University of California, Davis
PhD, University of California, Davis

Websites

MyNCBI - My Bibliography

ORCID : 0000-0002-1099-9175

I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.

I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.

Member
Boston University
Arthritis & Autoimmune Diseases Research Center

2020 Boston University Clinical and Translational Science Institute (BU-CTSI): Mini Sabbatical Award

2019 Rheumatology Research Foundation (RRF): Innovative Research Award

2018 Arthritis & Rheumatology: Editor’s Choice Article

2014 American College of Epidemiology (ACE): Travel Award

2013 American College of Epidemiology (ACE): Travel Award

2009-2010 University of California, Davis: Graduate Student Support Program (GSSP)

2007-2008 University of California, Davis: Epidemiology Graduate Group Fellowship

BU Research

Dynamic Treatment Regimens of Physical Activity for Persons with Osteoarthritis
09/01/2019 - 07/31/2021 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R21AR074578-02

Effects of NSAIDs and non-NSAID Analgesics on Osteoarthritis Outcomes
09/01/2018 - 05/31/2021 (PI)
NIH/National Institute on Aging
5R03AG060272-02

Global Awards for Advancing Chronic Pain Research (ADVANCE) 2018 _ NSAIDs, COX2 inhibitors, and opioids long-term effects on knee osteoarthritis progression and joint replacement
11/19/2018 - 12/31/2020 (PI)
Pfizer, Inc.

Personalized dynamic regimens of physical activity for persons with knee osteoarthritis
07/01/2019 - 09/30/2019 (PI)
Rheumatology Research Foundation

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Felson D, Rabasa G, Jafarzadeh SR, Nevitt M, Lewis CE, Segal N, White DK. Factors associated with pain resolution in those with knee pain: the MOST study. Osteoarthritis Cartilage. 2021 Apr 24.View Related Profiles.

Felson, David
Jafarzadeh, S. Reza

PMID: 33901642

McGrew KM, Garwe T, Jafarzadeh SR, Drevets DA, Zhao YD, Williams MB, Carabin H. Misclassification Error-Adjusted Prevalence of Injection Drug Use Among Infective Endocarditis Hospitalizations in the United States: A Serial Cross-Sectional Analysis of the 2007-2016 National Inpatient Sample. Am J Epidemiol. 2021 04 06; 190(4):588-599. PMID: 32997130

Macri EM, Neogi T, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner JC, Lynch JA, Tolstykh I, Jafarzadeh SR, Stefanik JJ. Can MRI-defined osteoarthritis features explain anterior knee pain in individuals with, or at risk for, knee osteoarthritis? The MOST Study. Arthritis Care Res (Hoboken). 2021 Mar 25.View Related Profiles.

Guermazi, Ali
Jafarzadeh, S. Reza
Neogi, Tuhina

PMID: 33768706

Fawole HO, Felson DT, Frey-Law LA, Jafarzadeh SR, Dell'Isola A, Steultjens MP, Nevitt MC, Lewis CE, Riskowski JL, Chastin S. Is the association between physical activity and fatigue mediated by physical function or depressive symptoms in symptomatic knee osteoarthritis? The Multicenter Osteoarthritis Study. Scand J Rheumatol. 2021 Mar 20; 1-9.View Related Profiles.

Felson, David
Jafarzadeh, S. Reza

PMID: 33749506

Sinha P, Jafarzadeh SR, Assoumou SA, Bielick CG, Carpenter B, Garg S, Harleen S, Neogi T, Nishio MJ, Sagar M, Sharp V, Kissin EY. The Effect of IL-6 Inhibitors on Mortality Among Hospitalized COVID-19 Patients: A Multicenter Study. J Infect Dis. 2021 02 24; 223(4):581-588.View Related Profiles.

Bielick, Catherine
Kissin, Eugene
Sagar, Manish
Sinha, Pranay
Jafarzadeh, S. Reza
Assoumou, Sabrina
Neogi, Tuhina

PMID: 33216906; PMCID: PMC7717300; DOI: 10.1093/infdis/jiaa717;

Ghaemmaghami P, Ayatollahi SMT, Bagheri Z, Jafarzadeh SR. Covariate-adjusted Bayesian estimation of the performance of a continuous diagnostic test with a limit of detection in the absence of a reference standard: a simulation study. Communications in Statistics - Simulation and Computation. 2021. View Publication

Bacon K, LaValley MP, Jafarzadeh SR, Felson D. Response to: 'Relation between cartilage loss and pain in knee osteoarthritis' by Wu et al and 'Changes in synovitis and bone marrow lesions may not mediate the effect of cartilage loss on joint pain in osteoarthritis' by Cashin et al. Ann Rheum Dis. 2020 Oct 07.View Related Profiles.

Felson, David
Bacon, Kathryn
LaValley, Michael
Jafarzadeh, S. Reza

PMID: 33028581

Law ST, Jafarzadeh SR, Govender P, Sun X, Sanchorawala V, Kissin EY. Comparison of Ultrasound Features of Major Salivary Glands in Sarcoidosis, Amyloidosis, and Sjögren's Syndrome. Arthritis Care Res (Hoboken). 2020 10; 72(10):1466-1473.View Related Profiles.

Kissin, Eugene
Govender, Praveen
Jafarzadeh, S. Reza
Sanchorawala, Vaishali

PMID: 31309727

Grammatico-Guillon L, Jafarzadeh SR, Laurent E, Shea K, Pasco J, Astagneau P, Adams W, Pelton S. Gradual decline in outpatient antibiotic prescriptions in paediatrics: A data warehouse-based 11-year cohort study. Acta Paediatr. 2021 02; 110(2):611-617.View Related Profiles.

Jafarzadeh, S. Reza
Pelton, Stephen

PMID: 32573837

Bacon K, LaValley MP, Jafarzadeh SR, Felson D. Does cartilage loss cause pain in osteoarthritis and if so, how much? Ann Rheum Dis. 2020 08; 79(8):1105-1110.View Related Profiles.

Felson, David
Bacon, Kathryn
LaValley, Michael
Jafarzadeh, S. Reza

PMID: 32381567

Showing 10 of 41 results. Show More

Kumar D, Link TM, Jafarzadeh SR, LaValley MP, Majumdar S, Souza RB. Association of Quadriceps Adiposity With an Increase in Knee Cartilage, Meniscus, or Bone Marrow Lesions Over Three Years. Arthritis Care Res (Hoboken). 2020 Apr 27.View Related Profiles.

Kumar, Deepak
LaValley, Michael
Jafarzadeh, S. Reza

PMID: 32339414; PMCID: PMC7606313; DOI: 10.1002/acr.24232;

McGrew KM, Carabin H, Garwe T, Jafarzadeh SR, Williams MB, Zhao YD, Drevets DA. Validity of ICD-based algorithms to estimate the prevalence of injection drug use among infective endocarditis hospitalizations in the absence of a reference standard. Drug Alcohol Depend. 2020 04 01; 209:107906. PMID: 32145659

Jafarzadeh SR, Neogi T, Stefanik JJ, Li JS, Guermazi A, Apovian CM, Felson DT. Mediating Role of Bone Marrow Lesions, Synovitis, Pain Sensitization, and Depressive Symptoms on Knee Pain Improvement Following Substantial Weight Loss. Arthritis Rheumatol. 2020 03; 72(3):420-427.View Related Profiles.

Guermazi, Ali
Apovian, Caroline
Felson, David
Jafarzadeh, S. Reza
Neogi, Tuhina

PMID: 31562683; PMCID: PMC7050338; DOI: 10.1002/art.41125;

McGrew KM, Homco JB, Garwe T, Dao HD, Williams MB, Drevets DA, Jafarzadeh SR, Zhao YD, Carabin H. Validity of International Classification of Diseases codes in identifying illicit drug use target conditions using medical record data as a reference standard: A systematic review. Drug Alcohol Depend. 2020 03 01; 208:107825. PMID: 31982637; DOI: 10.1016/j.drugalcdep.2019.107825;

Grammatico-Guillon L, Shea K, Jafarzadeh SR, Camelo I, Maakaroun-Vermesse Z, Figueira M, Adams WG, Pelton S. Antibiotic Prescribing in Outpatient Children: A Cohort From a Clinical Data Warehouse. Clin Pediatr (Phila). 2019 06; 58(6):681-690.View Related Profiles.

Figueira, Marisol
Jafarzadeh, S. Reza
Adams, William

PMID: 30884973; DOI: 10.1177/0009922819834278;

Dai Z, Jafarzadeh SR, Niu J, Felson DT, Jacques PF, Li S, Zhang Y. Body Mass Index Mediates the Association between Dietary Fiber and Symptomatic Knee Osteoarthritis in the Osteoarthritis Initiative and the Framingham Osteoarthritis Study. J Nutr. 2018 12 01; 148(12):1961-1967.View Related Profiles.

Felson, David
Jafarzadeh, S. Reza
Sheehy, Shanshan

PMID: 30517729; PMCID: PMC6857615; DOI: 10.1093/jn/nxy231;

Jafarzadeh SR, Felson DT. Reply. Arthritis Rheumatol. 2019 01; 71(1):175-176.View Related Profiles.

Felson, David
Jafarzadeh, S. Reza

PMID: 30251475; PMCID: PMC6310089; DOI: 10.1002/art.40732;

Gershon AS, Jafarzadeh SR, Wilson KC, Walkey AJ. Clinical Knowledge from Observational Studies. Everything You Wanted to Know but Were Afraid to Ask. Am J Respir Crit Care Med. 2018 10 01; 198(7):859-867.View Related Profiles.

Walkey, Allan
Wilson, Kevin
Jafarzadeh, S. Reza

PMID: 29733678; DOI: 10.1164/rccm.201801-0118PP;

Jafarzadeh SR, Clancy M, Li JS, Apovian CM, Guermazi A, Eckstein F, Felson DT. Changes in the structural features of osteoarthritis in a year of weight loss. Osteoarthritis Cartilage. 2018 06; 26(6):775-782.View Related Profiles.

Guermazi, Ali
Apovian, Caroline
Felson, David
Jafarzadeh, S. Reza

PMID: 29567521; PMCID: PMC5962405; DOI: 10.1016/j.joca.2018.03.003;

Durkin MJ, Jafarzadeh SR, Hsueh K, Sallah YH, Munshi KD, Henderson RR, Fraser VJ. Outpatient Antibiotic Prescription Trends in the United States: A National Cohort Study. Infect Control Hosp Epidemiol. 2018 05; 39(5):584-589. PMID: 29485018; PMCID: PMC7967296; DOI: 10.1017/ice.2018.26;

Jinno S, Lu N, Jafarzadeh SR, Dubreuil M. Trends in Hospitalizations for Serious Infections in Patients With Rheumatoid Arthritis in the US Between 1993 and 2013. Arthritis Care Res (Hoboken). 2018 04; 70(4):652-658.View Related Profiles.

Dubreuil, Maureen
Jafarzadeh, S. Reza

PMID: 28732148; PMCID: PMC5776053; DOI: 10.1002/acr.23328;

Munigala S, Jackups RR, Poirier RF, Liang SY, Wood H, Jafarzadeh SR, Warren DK. Impact of order set design on urine culturing practices at an academic medical centre emergency department. BMJ Qual Saf. 2018 08; 27(8):587-592. PMID: 29353243; PMCID: PMC6054549; DOI: 10.1136/bmjqs-2017-006899;

Jafarzadeh SR, Felson DT. Updated Estimates Suggest a Much Higher Prevalence of Arthritis in United States Adults Than Previous Ones. Arthritis Rheumatol. 2018 02; 70(2):185-192.View Related Profiles.

Felson, David
Jafarzadeh, S. Reza

PMID: 29178176; PMCID: PMC5788727; DOI: 10.1002/art.40355;

Durkin MJ, Hsueh K, Sallah YH, Feng Q, Jafarzadeh SR, Munshi KD, Lockhart PB, Thornhill MH, Henderson RR, Fraser VJ. An evaluation of dental antibiotic prescribing practices in the United States. J Am Dent Assoc. 2017 12; 148(12):878-886.e1. PMID: 28941554; PMCID: PMC5705569; DOI: 10.1016/j.adaj.2017.07.019;

Jafarzadeh SR, Felson DT. Corrected Estimates for the Prevalence of Self-Reported Doctor-Diagnosed Arthritis Among US Adults: Comment on the Article by Hootman et al. Arthritis Rheumatol. 2017 08; 69(8):1701-1702.View Related Profiles.

Felson, David
Jafarzadeh, S. Reza

PMID: 28482138; PMCID: PMC5529240; DOI: 10.1002/art.40144;

Munigala S, McMullen KM, Russo AJ, Jafarzadeh SR, Hoppe-Bauer J, Burnham CD, Warren DK. Reinstatement of Reflex Testing of Stool Samples for Vancomycin-Resistant Enterococci (VRE) Resulted in Decreased Incidence of Hospital-Associated VRE. Infect Control Hosp Epidemiol. 2017 05; 38(5):619-621. PMID: 28219459; PMCID: PMC5412709; DOI: 10.1017/ice.2017.19;

Hsueh K, Reyes M, Krekel T, Casabar E, Ritchie DJ, Jafarzadeh SR, Hays AJ, Lane MA, Durkin MJ. Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship During a Drug Shortage. Infect Control Hosp Epidemiol. 2017 Mar; 38(3):356-359. PMID: 27917734; PMCID: PMC8011860; DOI: 10.1017/ice.2016.289;

Jafarzadeh SR, Thomas BS, Gill J, Fraser VJ, Marschall J, Warren DK. Sepsis surveillance from administrative data in the absence of a perfect verification. Ann Epidemiol. 2016 Oct; 26(10):717-722.e1. PMID: 27600804; PMCID: PMC5086291; DOI: 10.1016/j.annepidem.2016.08.002;

Jafarzadeh SR, Thomas BS, Warren DK, Gill J, Fraser VJ. Longitudinal Study of the Effects of Bacteremia and Sepsis on 5-year Risk of Cardiovascular Events. Clin Infect Dis. 2016 Aug 15; 63(4):495-500. PMID: 27193746; PMCID: PMC4967600; DOI: 10.1093/cid/ciw320;

O'Neil C, Ball K, Wood H, McMullen K, Kremer P, Jafarzadeh SR, Fraser V, Warren D. A Central Line Care Maintenance Bundle for the Prevention of Central Line-Associated Bloodstream Infection in Non-Intensive Care Unit Settings. Infect Control Hosp Epidemiol. 2016 Jun; 37(6):692-8. PMID: 26999746; PMCID: PMC4874848; DOI: 10.1017/ice.2016.32;

Thomas BS, Jafarzadeh SR, Warren DK, McCormick S, Fraser VJ, Marschall J. Temporal trends in the systemic inflammatory response syndrome, sepsis, and medical coding of sepsis. BMC Anesthesiol. 2015; 15:169. PMID: 26597871; PMCID: PMC4657245; DOI: 10.1186/s12871-015-0148-z;

Jafarzadeh SR, Thomas BS, Marschall J, Fraser VJ, Gill J, Warren DK. Quantifying the improvement in sepsis diagnosis, documentation, and coding: the marginal causal effect of year of hospitalization on sepsis diagnosis. Ann Epidemiol. 2016 Jan; 26(1):66-70. PMID: 26559330; PMCID: PMC4688185; DOI: 10.1016/j.annepidem.2015.10.008;

Jafarzadeh SR, Johnson WO, Gardner IA. Bayesian modeling and inference for diagnostic accuracy and probability of disease based on multiple diagnostic biomarkers with and without a perfect reference standard. Stat Med. 2016 Mar 15; 35(6):859-76. PMID: 26415924; DOI: 10.1002/sim.6745;

Jafarzadeh SR, Warren DK, Nickel KB, Wallace AE, Fraser VJ, Olsen MA. Bayesian estimation of the accuracy of ICD-9-CM- and CPT-4-based algorithms to identify cholecystectomy procedures in administrative data without a reference standard. Pharmacoepidemiol Drug Saf. 2016 Mar; 25(3):263-8. PMID: 26349484; PMCID: PMC4775358; DOI: 10.1002/pds.3870;

Jafarzadeh SR, Norris M, Thurmond MC. Prediction of province-level outbreaks of foot-and-mouth disease in Iran using a zero-inflated negative binomial model. Prev Vet Med. 2014 Aug 1; 115(3-4):101-8. PMID: 24768434; DOI: 10.1016/j.prevetmed.2014.03.018;

Lombard JE, Gardner IA, Jafarzadeh SR, Fossler CP, Harris B, Capsel RT, Wagner BA, Johnson WO. Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis infection in United States dairy herds in 2007. Prev Vet Med. 2013 Feb 1; 108(2-3):234-8. PMID: 22979969; DOI: 10.1016/j.prevetmed.2012.08.006;

Jafarzadeh SR, Johnson WO, Utts JM, Gardner IA. Bayesian estimation of the receiver operating characteristic curve for a diagnostic test with a limit of detection in the absence of a gold standard. Stat Med. 2010 Sep 10; 29(20):2090-106. PMID: 20603894; DOI: 10.1002/sim.3975;

Safi S, Khoshvaghti A, Jafarzadeh SR, Bolourchi M, Nowrouzian I. Acute phase proteins in the diagnosis of bovine subclinical mastitis. Vet Clin Pathol. 2009 Dec; 38(4):471-6. PMID: 19548974; DOI: 10.1111/j.1939-165X.2009.00156.x;

Wheeler CA, Jafarzadeh SR, Rocke DM, Grodzinsky AJ. IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage. Osteoarthritis Cartilage. 2009 Jul; 17(7):944-52. PMID: 19250984; PMCID: PMC2752631; DOI: 10.1016/j.joca.2009.02.001;

Bakhtiari J, Fattahian HR, Gharagozlou MJ, Kajbafzadeh A, Jafarzadeh SR. Determination of the time required for appropriate chemical de-epithelialization of an ileal segment for cystoplasty: an animal model. BJU Int. 2005 Apr; 95(6):857-61. PMID: 15794798; DOI: 10.1111/j.1464-410X.2005.05416.x;

Jafarzadeh SR, Nowrouzian I, Khaki Z, Ghamsari SM, Adibhashemi F. The sensitivities and specificities of total plasma protein and plasma fibrinogen for the diagnosis of traumatic reticuloperitonitis in cattle. Prev Vet Med. 2004 Aug 30; 65(1-2):1-7. PMID: 15454322; DOI: 10.1016/j.prevetmed.2004.07.004;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 41 publications over 13 distinct years, with a maximum of 8 publications in 2018