S. Reza Jafarzadeh | Profiles RNS

S. Reza Jafarzadeh, DVM, MPVM, PhD

Assistant Professor

Boston University School of Medicine

Dept of Medicine

Clinical Epi Research & Training

DVM, University of Tehran
MPVM, University of California, Davis
PhD, University of California, Davis

Websites

Clinical Epidemiology Research and Training Unit

ORCID : 0000-0002-1099-9175

I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.

I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.

2018 Arthritis & Rheumatology: Editor’s Choice Article

2014 American College of Epidemiology (ACE): Travel Award

2013 American College of Epidemiology (ACE): Travel Award

2009-2010 University of California, Davis: Graduate Student Support Program (GSSP)

2007-2008 University of California, Davis: Epidemiology Graduate Group Fellowship

BU Sponsored Research

Global Awards for Advancing Chronic Pain Research (ADVANCE) 2018 _ NSAIDs, COX2 inhibitors, and opioids long-term effects on knee osteoarthritis progression and joint replacement
11/19/2018 - 12/31/2020 (PI)
Pfizer, Inc.

Effects of NSAIDs and non-NSAID Analgesics on Osteoarthritis Outcomes
09/01/2018 - 05/31/2020 (PI)
NIH/National Institute on Aging
1R03AG060272-01

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

Grammatico-Guillon L, Shea K, Jafarzadeh SR, Camelo I, Maakaroun-Vermesse Z, Figueira M, Adams WG, Pelton S. Antibiotic Prescribing in Outpatient Children: A Cohort From a Clinical Data Warehouse. Clin Pediatr (Phila). 2019 Jun; 58(6):681-690.View Related Profiles.
Figueira, Marisol
Jafarzadeh, S. Reza
Adams, William
PMID: 30884973; DOI: 10.1177/0009922819834278;.
Dai Z, Jafarzadeh SR, Niu J, Felson DT, Jacques PF, Li S, Zhang Y. Body Mass Index Mediates the Association between Dietary Fiber and Symptomatic Knee Osteoarthritis in the Osteoarthritis Initiative and the Framingham Osteoarthritis Study. J Nutr. 2018 12 01; 148(12):1961-1967.View Related Profiles.
Felson, David
Jafarzadeh, S. Reza
Sheehy, Shanshan
PMID: 30517729.
Jafarzadeh SR, Felson DT. Reply. Arthritis Rheumatol. 2019 Jan; 71(1):175-176.View Related Profiles.
Felson, David
Jafarzadeh, S. Reza
PMID: 30251475.
Gershon AS, Jafarzadeh SR, Wilson KC, Walkey AJ. Clinical Knowledge from Observational Studies. Everything You Wanted to Know but Were Afraid to Ask. Am J Respir Crit Care Med. 2018 Oct 01; 198(7):859-867.View Related Profiles.
Walkey, Allan
Wilson, Kevin
Jafarzadeh, S. Reza
PMID: 29733678; DOI: 10.1164/rccm.201801-0118PP;.
Jafarzadeh SR, Clancy M, Li JS, Apovian CM, Guermazi A, Eckstein F, Felson DT. Changes in the structural features of osteoarthritis in a year of weight loss. Osteoarthritis Cartilage. 2018 Jun; 26(6):775-782.View Related Profiles.
Guermazi, Ali
Apovian, Caroline
Felson, David
Jafarzadeh, S. Reza
PMID: 29567521.
Durkin MJ, Jafarzadeh SR, Hsueh K, Sallah YH, Munshi KD, Henderson RR, Fraser VJ. Outpatient Antibiotic Prescription Trends in the United States: A National Cohort Study. Infect Control Hosp Epidemiol. 2018 05; 39(5):584-589. PMID: 29485018.
Jinno S, Lu N, Jafarzadeh SR, Dubreuil M. Trends in Hospitalizations for Serious Infections in Patients With Rheumatoid Arthritis in the US Between 1993 and 2013. Arthritis Care Res (Hoboken). 2018 04; 70(4):652-658.View Related Profiles.
Dubreuil, Maureen
Jafarzadeh, S. Reza
PMID: 28732148.
Munigala S, Jackups RR, Poirier RF, Liang SY, Wood H, Jafarzadeh SR, Warren DK. Impact of order set design on urine culturing practices at an academic medical centre emergency department. BMJ Qual Saf. 2018 08; 27(8):587-592. PMID: 29353243.
Jafarzadeh SR, Felson DT. Updated Estimates Suggest a Much Higher Prevalence of Arthritis in United States Adults Than Previous Ones. Arthritis Rheumatol. 2018 02; 70(2):185-192.View Related Profiles.
Felson, David
Jafarzadeh, S. Reza
PMID: 29178176; DOI: 10.1002/art.40355;.
Durkin MJ, Hsueh K, Sallah YH, Feng Q, Jafarzadeh SR, Munshi KD, Lockhart PB, Thornhill MH, Henderson RR, Fraser VJ. An evaluation of dental antibiotic prescribing practices in the United States. J Am Dent Assoc. 2017 Dec; 148(12):878-886.e1. PMID: 28941554.

Showing 10 of 27 results. Show More

Jafarzadeh SR, Felson DT. Corrected Estimates for the Prevalence of Self-Reported Doctor-Diagnosed Arthritis Among US Adults: Comment on the Article by Hootman et al. Arthritis Rheumatol. 2017 08; 69(8):1701-1702.View Related Profiles.
Felson, David
Jafarzadeh, S. Reza
PMID: 28482138; DOI: 10.1002/art.40144;.
Munigala S, McMullen KM, Russo AJ, Jafarzadeh SR, Hoppe-Bauer J, Burnham CD, Warren DK. Reinstatement of Reflex Testing of Stool Samples for Vancomycin-Resistant Enterococci (VRE) Resulted in Decreased Incidence of Hospital-Associated VRE. Infect Control Hosp Epidemiol. 2017 05; 38(5):619-621. PMID: 28219459; DOI: 10.1017/ice.2017.19;.
Hsueh K, Reyes M, Krekel T, Casabar E, Ritchie DJ, Jafarzadeh SR, Hays AJ, Lane MA, Durkin MJ. Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship During a Drug Shortage. Infect Control Hosp Epidemiol. 2017 Mar; 38(3):356-359. PMID: 27917734; DOI: 10.1017/ice.2016.289;.
Jafarzadeh SR, Thomas BS, Gill J, Fraser VJ, Marschall J, Warren DK. Sepsis surveillance from administrative data in the absence of a perfect verification. Ann Epidemiol. 2016 Oct; 26(10):717-722.e1. PMID: 27600804; DOI: 10.1016/j.annepidem.2016.08.002;.
Jafarzadeh SR, Thomas BS, Warren DK, Gill J, Fraser VJ. Longitudinal Study of the Effects of Bacteremia and Sepsis on 5-year Risk of Cardiovascular Events. Clin Infect Dis. 2016 Aug 15; 63(4):495-500. PMID: 27193746; DOI: 10.1093/cid/ciw320;.
O'Neil C, Ball K, Wood H, McMullen K, Kremer P, Jafarzadeh SR, Fraser V, Warren D. A Central Line Care Maintenance Bundle for the Prevention of Central Line-Associated Bloodstream Infection in Non-Intensive Care Unit Settings. Infect Control Hosp Epidemiol. 2016 Jun; 37(6):692-8. PMID: 26999746; PMCID: PMC4874848; DOI: 10.1017/ice.2016.32;.
Thomas BS, Jafarzadeh SR, Warren DK, McCormick S, Fraser VJ, Marschall J. Temporal trends in the systemic inflammatory response syndrome, sepsis, and medical coding of sepsis. BMC Anesthesiol. 2015; 15:169. PMID: 26597871; PMCID: PMC4657245; DOI: 10.1186/s12871-015-0148-z;.
Jafarzadeh SR, Thomas BS, Marschall J, Fraser VJ, Gill J, Warren DK. Quantifying the improvement in sepsis diagnosis, documentation, and coding: the marginal causal effect of year of hospitalization on sepsis diagnosis. Ann Epidemiol. 2016 Jan; 26(1):66-70. PMID: 26559330; PMCID: PMC4688185; DOI: 10.1016/j.annepidem.2015.10.008;.
Jafarzadeh SR, Johnson WO, Gardner IA. Bayesian modeling and inference for diagnostic accuracy and probability of disease based on multiple diagnostic biomarkers with and without a perfect reference standard. Stat Med. 2016 Mar 15; 35(6):859-76. PMID: 26415924; DOI: 10.1002/sim.6745;.
Jafarzadeh SR, Warren DK, Nickel KB, Wallace AE, Fraser VJ, Olsen MA. Bayesian estimation of the accuracy of ICD-9-CM- and CPT-4-based algorithms to identify cholecystectomy procedures in administrative data without a reference standard. Pharmacoepidemiol Drug Saf. 2016 Mar; 25(3):263-8. PMID: 26349484; PMCID: PMC4775358; DOI: 10.1002/pds.3870;.
Jafarzadeh SR, Norris M, Thurmond MC. Prediction of province-level outbreaks of foot-and-mouth disease in Iran using a zero-inflated negative binomial model. Prev Vet Med. 2014 Aug 1; 115(3-4):101-8. PMID: 24768434; DOI: 10.1016/j.prevetmed.2014.03.018;.
Lombard JE, Gardner IA, Jafarzadeh SR, Fossler CP, Harris B, Capsel RT, Wagner BA, Johnson WO. Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis infection in United States dairy herds in 2007. Prev Vet Med. 2013 Feb 1; 108(2-3):234-8. PMID: 22979969; DOI: 10.1016/j.prevetmed.2012.08.006;.
Jafarzadeh SR, Johnson WO, Utts JM, Gardner IA. Bayesian estimation of the receiver operating characteristic curve for a diagnostic test with a limit of detection in the absence of a gold standard. Stat Med. 2010 Sep 10; 29(20):2090-106. PMID: 20603894; DOI: 10.1002/sim.3975;.
Safi S, Khoshvaghti A, Jafarzadeh SR, Bolourchi M, Nowrouzian I. Acute phase proteins in the diagnosis of bovine subclinical mastitis. Vet Clin Pathol. 2009 Dec; 38(4):471-6. PMID: 19548974; DOI: 10.1111/j.1939-165X.2009.00156.x;.
Wheeler CA, Jafarzadeh SR, Rocke DM, Grodzinsky AJ. IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage. Osteoarthritis Cartilage. 2009 Jul; 17(7):944-52. PMID: 19250984; PMCID: PMC2752631; DOI: 10.1016/j.joca.2009.02.001;.
Bakhtiari J, Fattahian HR, Gharagozlou MJ, Kajbafzadeh A, Jafarzadeh SR. Determination of the time required for appropriate chemical de-epithelialization of an ileal segment for cystoplasty: an animal model. BJU Int. 2005 Apr; 95(6):857-61. PMID: 15794798; DOI: 10.1111/j.1464-410X.2005.05416.x;.
Jafarzadeh SR, Nowrouzian I, Khaki Z, Ghamsari SM, Adibhashemi F. The sensitivities and specificities of total plasma protein and plasma fibrinogen for the diagnosis of traumatic reticuloperitonitis in cattle. Prev Vet Med. 2004 Aug 30; 65(1-2):1-7. PMID: 15454322; DOI: 10.1016/j.prevetmed.2004.07.004;.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 27 publications over 11 distinct years, with a maximum of 8 publications in 2018