S. Reza Jafarzadeh, DVM, MPVM, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Clinical Epi Research & Training

DVM, University of Tehran
MPVM, University of California, Davis
PhD, University of California, Davis

I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.

I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.

2018 Arthritis & Rheumatology: Editor’s Choice Article
2014 American College of Epidemiology (ACE): Travel Award
2013 American College of Epidemiology (ACE): Travel Award
2009-2010 University of California, Davis: Graduate Student Support Program (GSSP)
2007-2008 University of California, Davis: Epidemiology Graduate Group Fellowship

Global Awards for Advancing Chronic Pain Research (ADVANCE) 2018 _ NSAIDs, COX2 inhibitors, and opioids long-term effects on knee osteoarthritis progression and joint replacement
11/19/2018 - 12/31/2020 (PI)
Pfizer, Inc.

Effects of NSAIDs and non-NSAID Analgesics on Osteoarthritis Outcomes
09/01/2018 - 05/31/2020 (PI)
NIH/National Institute on Aging

Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Grammatico-Guillon L, Shea K, Jafarzadeh SR, Camelo I, Maakaroun-Vermesse Z, Figueira M, Adams WG, Pelton S. Antibiotic Prescribing in Outpatient Children: A Cohort From a Clinical Data Warehouse. Clin Pediatr (Phila). 2019 Jun; 58(6):681-690.View Related Profiles. PMID: 30884973; DOI: 10.1177/0009922819834278;.
  2. Dai Z, Jafarzadeh SR, Niu J, Felson DT, Jacques PF, Li S, Zhang Y. Body Mass Index Mediates the Association between Dietary Fiber and Symptomatic Knee Osteoarthritis in the Osteoarthritis Initiative and the Framingham Osteoarthritis Study. J Nutr. 2018 12 01; 148(12):1961-1967.View Related Profiles. PMID: 30517729.
  3. Jafarzadeh SR, Felson DT. Reply. Arthritis Rheumatol. 2019 Jan; 71(1):175-176.View Related Profiles. PMID: 30251475.
  4. Gershon AS, Jafarzadeh SR, Wilson KC, Walkey AJ. Clinical Knowledge from Observational Studies. Everything You Wanted to Know but Were Afraid to Ask. Am J Respir Crit Care Med. 2018 Oct 01; 198(7):859-867.View Related Profiles. PMID: 29733678; DOI: 10.1164/rccm.201801-0118PP;.
  5. Jafarzadeh SR, Clancy M, Li JS, Apovian CM, Guermazi A, Eckstein F, Felson DT. Changes in the structural features of osteoarthritis in a year of weight loss. Osteoarthritis Cartilage. 2018 Jun; 26(6):775-782.View Related Profiles. PMID: 29567521.
  6. Durkin MJ, Jafarzadeh SR, Hsueh K, Sallah YH, Munshi KD, Henderson RR, Fraser VJ. Outpatient Antibiotic Prescription Trends in the United States: A National Cohort Study. Infect Control Hosp Epidemiol. 2018 05; 39(5):584-589. PMID: 29485018.
  7. Jinno S, Lu N, Jafarzadeh SR, Dubreuil M. Trends in Hospitalizations for Serious Infections in Patients With Rheumatoid Arthritis in the US Between 1993 and 2013. Arthritis Care Res (Hoboken). 2018 04; 70(4):652-658.View Related Profiles. PMID: 28732148.
  8. Munigala S, Jackups RR, Poirier RF, Liang SY, Wood H, Jafarzadeh SR, Warren DK. Impact of order set design on urine culturing practices at an academic medical centre emergency department. BMJ Qual Saf. 2018 08; 27(8):587-592. PMID: 29353243.
  9. Jafarzadeh SR, Felson DT. Updated Estimates Suggest a Much Higher Prevalence of Arthritis in United States Adults Than Previous Ones. Arthritis Rheumatol. 2018 02; 70(2):185-192.View Related Profiles. PMID: 29178176; DOI: 10.1002/art.40355;.
  10. Durkin MJ, Hsueh K, Sallah YH, Feng Q, Jafarzadeh SR, Munshi KD, Lockhart PB, Thornhill MH, Henderson RR, Fraser VJ. An evaluation of dental antibiotic prescribing practices in the United States. J Am Dent Assoc. 2017 Dec; 148(12):878-886.e1. PMID: 28941554.
Showing 10 of 27 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 27 publications over 11 distinct years, with a maximum of 8 publications in 2018

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Bayesian Methods
Causal Inference
Diagnostic Tests Evaluation
Estimation of True Prevalence with Imperfect Tests
Machine Learning

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
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650 Albany Street, Suite X200
Boston MA 02118
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(617) 638-5239 (fax)

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