Ozge Erdogan, DDS, DMSc
Assistant Professor
Boston University Henry M. Goldman School of Dental Medicine
Endodontics

DMSc, Harvard School of Dental Medicine
DDS, Yeditepe Universitesi



Dr. Ozge Erdogan is a dentist-scientist with formal training in dentistry (DDS, Yeditepe University, Istanbul, Turkey), endodontics (Hacettepe University, Ankara, Turkey), and oral biology (DMSc, Harvard School of Dental Medicine), followed by postdoctoral training in neuroimmunology at Harvard Medical School. Her research expertise lies at the intersection of clinical endodontics, neuroscience, and immunology, with a focus on elucidating the mechanisms that regulate dental pain, inflammation, and host responses in oral tissues. Building on her clinical and scientific training, her work integrates preclinical models of dental disease, prospective human studies, and advanced experimental approaches, including transcriptomics, chemogenetic manipulation of sensory neurons, tissue clearing, and in vitro assays to investigate neuro-immune interactions in the dental pulp.

Dr. Erdogan’s professional interests center on developing a rigorous translational research program that bridges neuroscience, immunology, and microbiology to advance the understanding and treatment of oral diseases. Her independent research aims to define how sensory neurons interact with immune cells and the oral microbiome to influence disease progression, pain, and tissue repair, with the long-term goal of enabling more precise diagnostics and less invasive therapeutic strategies. In addition to her research, she is committed to mentoring trainees and contributing to clinical and didactic education in endodontics, while maintaining a strong connection to patient care.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Almanzar N, Yang D, Xia J, Udit S, Joshi P, Adhikari S, Hoagland DA, Yeung ST, Khairallah C, Huerta T, Wallrapp A, Umans BD, Sarden N, Erdogan O, Baalbaki N, Hou J, Beekmayer-Dhillon A, Lee J, Meerschaert KA, Liberles SD, Franklin RA, Yipp BG, Khanna KM, Baral P, Haber AL, Chiu IM. Vagal TRPV1+ sensory neurons protect against influenza virus infection by regulating lung myeloid cell dynamics. Sci Immunol. 2025 Aug; 10(110):eads6243. PMID: 40749036; DOI: 10.1126/sciimmunol.ads6243;
     
  2. Erdogan O, Hu XQ, Chiu IM. Sensory neurons on guard: roles in pathogen defense and host immunity. Curr Opin Immunol. 2025 Apr; 93:102541. PMID: 40015178; PMCID: PMC11884989; DOI: 10.1016/j.coi.2025.102541;
     
  3. Malek M, Steff L, Vakil N, Jothilingam R, Huh S, Chien T, Halpern R, Gencerliler N, Erdogan O, Songtrakul K. Biological Markers in the Gingival Crevicular Fluid Associated with External Invasive Resorption: A Split-Mouth Cross-Sectional Study. J Endod. 2025 Feb; 51(2):150-156.e1. PMID: 39617293; DOI: 10.1016/j.joen.2024.11.013;
     
  4. Erdogan O, Casey SM, Bahammam A, Son M, Mora M, Park G, Fox D, Flake N, Khan A, Gibbs JL. Radiographic Evaluation of Regenerative Endodontic Procedures and Apexification Treatments with the Assessment of External Root Resorption. J Endod. 2024 Oct; 50(10):1420-1428.e1. PMID: 38878998; DOI: 10.1016/j.joen.2024.06.003;
     
  5. Erdogan O, Michot B, Xia J, Alabdulaaly L, Yesares Rubi P, Ha V, Chiu IM, Gibbs JL. Neuronal-immune axis alters pain and sensory afferent damage during dental pulp injury. Pain. 2024 Feb 01; 165(2):392-403. PMID: 37903298; DOI: 10.1097/j.pain.0000000000003029;
     
  6. Erdogan O, Xia J, Chiu IM, Gibbs JL. Dynamics of Innate Immune Response in Bacteria-Induced Mouse Model of Pulpitis. J Endod. 2023 Nov; 49(11):1529-1536. PMID: 37678750; DOI: 10.1016/j.joen.2023.08.019;
     
  7. Michot B, Casey SM, Lee CS, Erdogan O, Basu H, Chiu I, Gibbs JL. Lipopolysaccharide-Induced TRPA1 Upregulation in Trigeminal Neurons is Dependent on TLR4 and Vesicular Exocytosis. J Neurosci. 2023 Oct 04; 43(40):6731-6744. PMID: 37643860; PMCID: PMC10552941; DOI: 10.1523/JNEUROSCI.0162-23.2023;
     
  8. Nunez N, Erdogan O, Casey SM, Hernandez R, Tan S, Gibbs JL. Elevated Cytokine Levels in Gingival Crevicular Fluid of Teeth with Apical Periodontitis. J Endod. 2023 Jun; 49(6):657-663. PMID: 36965768; DOI: 10.1016/j.joen.2023.03.010;
     
  9. Pinho-Ribeiro FA, Deng L, Neel DV, Erdogan O, Basu H, Yang D, Choi S, Walker AJ, Carneiro-Nascimento S, He K, Wu G, Stevens B, Doran KS, Levy D, Chiu IM. Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature. 2023 Mar; 615(7952):472-481. PMID: 36859544; PMCID: PMC10593113; DOI: 10.1038/s41586-023-05753-x;
     
  10. De Armas V, Erdogan O, Yoon H, Abdennour M, Gibbs JL. Contribution of Endodontic Pathology to Persistent Orofacial Pain: A Case Report. J Endod. 2022 Sep; 48(9):1178-1184. PMID: 35793740; DOI: 10.1016/j.joen.2022.06.010;
     
Showing 10 of 19 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 19 publications over 8 distinct years, with a maximum of 5 publications in 2023

YearPublications
20162
20181
20191
20212
20224
20235
20242
20252


2025 American Association for Dental, Oral and Craniofacial Research: Anne D. Haffajee Fellowship
2022 Harvard School of Dental Medicine: Dr. James H. Shaw Award
2022 Harvard School of Dental Medicine: Alvin Krakow Research Award
2022 International Association for the Study of Pain: International Association for the Study of Pain Travel Grant
2020-2022 Harvard University: Presidential Scholar
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Dental Pulp, Neuroimmunology, Pain

Dr. Ozge Erdogan is committed to mentoring students and trainees in a supportive, collaborative, and intellectually engaging environment. She values diverse perspectives and strives to create an inclusive and respectful space where all trainees feel encouraged to contribute, ask questions, and grow. Her mentorship emphasizes curiosity, critical thinking, and scientific rigor while providing individualized guidance aligned with each trainee’s goals. She is dedicated to training the next generation of clinicians and scientists and clinician-scientists by integrating research, clinical insight, and professional development, and by fostering collaborative opportunities for meaningful participation in preclinical, translational, and clinical research.

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

635 Albany St
Boston MA 02118
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