Melissa Hughes, MD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
General Internal Medicine




I am the Clinical Director for Palliative Care at the Boston VA Brockton Campus, overseeing a 15-bed hospice unit as well as palliative care consults in the long-term care setting.

After graduating medical school from the Icahn School of Medicine at Mt. Sinai, I completed a General Surgery residency in Long Island NY followed by a Breast Surgical Oncology Fellowship in Buffalo NY. After practicing as a breast surgeon for several years, I then completed a Hospice and Palliative Care Fellowship in Buffalo NY and am now dedicating my practice to Hospice and Palliative Care. I am board certified in General Surgery and Hospice and Palliative Care.

I enjoy teaching the fellows and residents who rotate at the VA Brockton Campus who come from multiple programs throughout Boston. My clinical interests include complex pain and symptom management, end of life care, and bereavement support.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Priedigkeit N, Harrison B, Shue R, Hughes ME, Li Y, Lebrón-Torres A, Kirkner GJ, Spurr LF, Remolano MC, Strauss S, Files J, Feeney AM, Grant L, Mohammed-Abreu A, Garrido-Castro A, Barroso-Sousa R, Bychkovsky B, Nakhlis F, Bellon JR, King TA, Winer EP, Lindeman N, Johnson BE, Sholl L, Dillon D, Overmoyer B, Tolaney SM, Cherniack AD, Lin NU, Lynce F. Clinicogenomic Characterization of Inflammatory Breast Cancer. Clin Cancer Res. 2025 Jul 15; 31(14):3072-3083. PMID: 40378057; DOI: 10.1158/1078-0432.CCR-24-2081;
     
  2. Goel S, Jovanovic B, Chu X, Hughes M, Erick TK, Russo D, DiLullo M, Wrabel E, Jeselsohn R, Lin NU, Tayob N, Mittendorf E, Schnitt S, Tolaney SM. A Phase II Study of Abemaciclib for Patients with Retinoblastoma-Positive, Metastatic Triple-Negative Breast Cancer. Clin Cancer Res. 2025 Apr 14; 31(8):1427-1436. PMID: 39908010; DOI: 10.1158/1078-0432.CCR-24-2647;
     
  3. Rosenberg SM, Zheng Y, Santos K, Riley E, Meadows HW, Snow C, Hughes ME, Frank E, Lin NU, Partridge AH, Winer EP, Parsons HA. Patient-reported outcomes, and perceptions and knowledge about recurrence in women with hormone receptor-positive breast cancer. Breast Cancer Res Treat. 2025 Feb; 209(3):513-520. PMID: 39432162
     
  4. Jovanovic B, Church SE, Gorman KM, North K, Richardson ET, DiLullo M, Attaya V, Kasparian J, Mohammed-Abreu A, Kirkner G, Hughes ME, Lin NU, Mittendorf EA, Schnitt SJ, Tolaney SM, Goel S. Integrative Multiomic Profiling of Triple-Negative Breast Cancer for Identifying Suitable Therapies. Clin Cancer Res. 2024 Oct 15; 30(20):4768-4779. PMID: 39136550; DOI: 10.1158/1078-0432.CCR-23-1242;
     
  5. Erick TK, Lester SC, Garrido-Castro AC, Hughes M, Cunningham O, Lin NU, Mittendorf EA, Tolaney SM, Brock JE. Concordance of PD-L1 Expression in Metastatic Triple-negative Breast Cancer Between the 22C3 and E1L3N Antibodies Using Combined Positive Scoring. Appl Immunohistochem Mol Morphol. 2024 Oct 01; 32(9):417-424. PMID: 39351784
     
  6. Lipsyc-Sharf M, de Bruin EC, Santos K, McEwen R, Stetson D, Patel A, Kirkner GJ, Hughes ME, Tolaney SM, Partridge AH, Krop IE, Knape C, Feger U, Marsico G, Howarth K, Winer EP, Lin NU, Parsons HA. Circulating Tumor DNA and Late Recurrence in High-Risk Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer. J Clin Oncol. 2022 Aug 01; 40(22):2408-2419. PMID: 35658506
     
  7. Tung NM, Robson ME, Ventz S, Santa-Maria CA, Nanda R, Marcom PK, Shah PD, Ballinger TJ, Yang ES, Vinayak S, Melisko M, Brufsky A, DeMeo M, Jenkins C, Domchek S, D'Andrea A, Lin NU, Hughes ME, Carey LA, Wagle N, Wulf GM, Krop IE, Wolff AC, Winer EP, Garber JE. TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes. J Clin Oncol. 2020 Dec 20; 38(36):4274-4282. PMID: 33119476
     
  8. Yang DD, Buscariollo DL, Cronin AM, Weng S, Hughes ME, Bleicher RJ, Cohen AL, Javid SH, Edge SB, Moy B, Niland JC, Wolff AC, Hassett MJ, Punglia RS. Association between the 21-gene recurrence score and isolated locoregional recurrence in stage I-II, hormone receptor-positive breast cancer. Radiat Oncol. 2020 Aug 17; 15(1):198. PMID: 32799886
     
  9. Knelson LP, Cukras AR, Savoie J, Agarwal A, Guo H, Hu J, Fell G, Lederman R, Hughes ME, Winer EP, Lin NU, Tolaney SM. Barriers to Clinical Trial Accrual: Perspectives of Community-Based Providers. Clin Breast Cancer. 2020 Oct; 20(5):395-401.e3. PMID: 32605813
     
  10. Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D, Cohen O, Yu F, Fitarelli-Kiehl M, Leong KW, Hughes ME, Rosenberg SM, Collins LC, Miller KD, Blumenstiel B, Trippa L, Cibulskis C, Neuberg DS, DeFelice M, Freeman SS, Lennon NJ, Wagle N, Ha G, Stover DG, Choudhury AD, Getz G, Winer EP, Meyerson M, Lin NU, Krop I, Love JC, Makrigiorgos GM, Partridge AH, Mayer EL, Golub TR, Adalsteinsson VA. Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer. Clin Cancer Res. 2020 Jun 01; 26(11):2556-2564. PMID: 32170028
     
Showing 10 of 28 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 28 publications over 13 distinct years, with a maximum of 5 publications in 2020

YearPublications
20091
20113
20122
20144
20151
20161
20172
20182
20191
20205
20221
20243
20252


2023 Fellow Humanism Award
Contact for Mentoring:
Hughes's Networks
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