Melanie Brennan
Predoctoral Trainee
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Neuroscience



Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Habich C, Kowalski A, Wachter A, Heimann MJ, Wolf M, Kummer MP, Nicolaisen N, Sliwinski C, Reinhardt L, Heil V, Lange T, Untucht C, Miller LN, Korffmann J, Geist D, Schöndorf D, Lee H, Bahnassawy L, Mielich-Süss B, Brennan MS, Wilkens R, Röwe J, Weidling I, Rudolf R, Hafner M, Manos JD, Cik M, Reinhardt P. BMP, MEK, and WNT inhibition with NGN2 expression for rapid generation of hiPSC-derived neurons amenable to regional patterning. Stem Cell Reports. 2025 Jul 08; 20(7):102539. PMID: 40541177; PMCID: PMC12277818; DOI: 10.1016/j.stemcr.2025.102539;
     
  2. Weidling I, Preiss CN, Chancellor SE, Srivastava G, Gibilisco L, Lin G, Brennan MS, Lee J, Roth LM, Morozova O, Nam KN, Patel NR, Liu Q, Thomas JK, Reinhardt P, Wilkens R, Ehrnhoefer DE, Striebinger A, Barghorn S, Xanthopoulos C, Weil MT, Biesinger S, Cik M, Romanul N, Yanamandra K, Welker AM, Wu J, Gasparini L, Stöhr J, Langlois X, Manos JD. hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation. Acta Neuropathol Commun. 2025 May 19; 13(1):108. PMID: 40390134; PMCID: PMC12087151; DOI: 10.1186/s40478-025-02000-4;
     
  3. Wipke BT, Hoepner R, Strassburger-Krogias K, Thomas AM, Gianni D, Szak S, Brennan MS, Pistor M, Gold R, Chan A, Scannevin RH. Different Fumaric Acid Esters Elicit Distinct Pharmacologic Responses. Neurol Neuroimmunol Neuroinflamm. 2021 03; 8(2). PMID: 33468560; PMCID: PMC7862084; DOI: 10.1212/NXI.0000000000000950;
     
  4. Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A. Addendum: The antibody aducanumab reduces Aß plaques in Alzheimer's disease. Nature. 2017 06 21; 546(7659):564. PMID: 28640269
     
  5. Brennan MS, Matos MF, Richter KE, Li B, Scannevin RH. The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes. Sci Rep. 2017 02 09; 7:42054. PMID: 28181536; PMCID: PMC5299414; DOI: 10.1038/srep42054;
     
  6. Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A. The antibody aducanumab reduces Aß plaques in Alzheimer's disease. Nature. 2016; 537(7618):50-6. PMID: 27582220; DOI: 10.1038/nature19323;
     
  7. Brennan MS, Patel H, Allaire N, Thai A, Cullen P, Ryan S, Lukashev M, Bista P, Huang R, Rhodes KJ, Scannevin RH. Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms. Antioxid Redox Signal. 2016 Jun 20; 24(18):1058-71. PMID: 26980071; DOI: 10.1089/ars.2015.6622;
     
  8. Scannevin RH, Chollate S, Brennan MS, Snodgrass-Belt PA, Peng H, Xu L, Jung MY, Bussiere T, Arastu MF, Talreja T, Xin Z, Dunstan RW, Fahrer D, Rohde E, Dunah AW, Wang J, Kumaravel G, Taveras AG, Moore Arnold H, Rhodes KJ. BIIB042, a novel ?-secretase modulator, reduces amyloidogenic Aß isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease. Neuropharmacology. 2016 Apr; 103:57-68. PMID: 26690893; DOI: 10.1016/j.neuropharm.2015.12.006;
     
  9. Brennan MS, Matos MF, Li B, Hronowski X, Gao B, Juhasz P, Rhodes KJ, Scannevin RH. Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro. PLoS One. 2015; 10(3):e0120254. PMID: 25793262; PMCID: PMC4368598; DOI: 10.1371/journal.pone.0120254;
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 9 publications over 5 distinct years, with a maximum of 2 publications in 2015 and 2016 and 2017 and 2025

YearPublications
20152
20162
20172
20211
20252

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