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PhD, University of Connecticut Health Center
MS, Saint Joseph College





THE EFFECT OF TLR4 ANTAGONISTS ON B CELL ACTIVATION FROM TYPE 2 DIAB ETES PATIENTS
04/01/2011 - 03/31/2012 (PI)
NovImmune SA


THE EFFECT OF TLR4 ANTAGONISTS ON B CELL ACTIVATION FROM TYPE 2 DIAB ETES PATIENTS
04/01/2011 - 03/31/2012 (PI)
NovImmune SA



Human IgE responses to schistosomal calpain
09/01/2010 - 08/31/2011 (PI)
Texas Tech University

Human B cells as potential mediators of inflammation in chronic inflammatory disease
11/01/2008 - 06/30/2011 (PI)
Broad (Eli & Edythe) Foundation

The role of CD23+ B cells in human schistosomiasis
03/01/2008 - 02/28/2011 (PI)
NIH-NIAID
5R21 AI074843-02


Title


Yr Title Project-Sub Proj Pubs
2018 The Role of IgE in Human Schistosomiasis 5R01AI116593-05 1
2017 The role of IgE in human schistosomiasis 5R01AI116593-03 1
2017 The Role of IgE in Human Schistosomiasis 7R01AI116593-04 1
2016 The role of IgE in human schistosomiasis 5R01AI116593-02 1
2015 The role of IgE in human schistosomiasis 1R01AI116593-01 1
2013 The human B cell toll-like receptor 4 complex 5R21AI097684-02 2
2012 The human B cell toll-like receptor 4 complex 1R21AI097684-01A1 2
2009 Transformation of Cells by the REL Oncogene 3R01CA047763-21S1 73
2009 The role of CD23+ B cells in human schistosomiasis 5R21AI074843-02 6
2008 The role of CD23+ B cells in human schistosomiasis 1R21AI074843-01A2 6
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Onguru D, Liang Y, Elliot J, Mwinzi P, Ganley-Leal L. CD23b isoform expression in human schistosomiasis identifies a novel subset of activated B cells. Infect Immun. 2011 Sep; 79(9):3770-7. PMID: 21708991; PMCID: PMC3165463; DOI: 10.1128/IAI.05094-11;
     
  2. Onguru D, Liang Y, Griffith Q, Nikolajczyk B, Mwinzi P, Ganley-Leal L. Human schistosomiasis is associated with endotoxemia and Toll-like receptor 2- and 4-bearing B cells. Am J Trop Med Hyg. 2011 Feb; 84(2):321-4.View Related Profiles. PMID: 21292908; PMCID: PMC3029191; DOI: 10.4269/ajtmh.2011.10-0397;
     
  3. Griffith QK, Liang Y, Onguru DO, Mwinzi PN, Ganley-Leal LM. CD23-bound IgE augments and dominates recall responses through human naive B cells. J Immunol. 2011 Jan 15; 186(2):1060-7. PMID: 21160045; DOI: 10.4049/jimmunol.1002709;
     
  4. Ganley-Leal LM, Liang Y, Jagannathan-Bogdan M, Farraye FA, Nikolajczyk BS. Differential regulation of TLR4 expression in human B cells and monocytes. Mol Immunol. 2010 Nov-Dec; 48(1-3):82-8.View Related Profiles. PMID: 20956019; PMCID: PMC2993761; DOI: 10.1016/j.molimm.2010.09.008;
     
  5. Liang Y, Hasturk H, Elliot J, Noronha A, Liu X, Wetzler LM, Massari P, Kantarci A, Winter HS, Farraye FA, Ganley-Leal LM. Toll-like receptor 2 induces mucosal homing receptor expression and IgA production by human B cells. Clin Immunol. 2011 Jan; 138(1):33-40.View Related Profiles. PMID: 20947433; DOI: 10.1016/j.clim.2010.09.003;
     
  6. McDonnell M, Liang Y, Noronha A, Coukos J, Kasper DL, Farraye FA, Ganley-Leal LM. Systemic Toll-like receptor ligands modify B-cell responses in human inflammatory bowel disease. Inflamm Bowel Dis. 2011 Jan; 17(1):298-307.View Related Profiles. PMID: 20806343; DOI: 10.1002/ibd.21424;
     
  7. Jagannathan M, McDonnell M, Liang Y, Hasturk H, Hetzel J, Rubin D, Kantarci A, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. Toll-like receptors regulate B cell cytokine production in patients with diabetes. Diabetologia. 2010 Jul; 53(7):1461-71.View Related Profiles. PMID: 20383694; PMCID: PMC2895399; DOI: 10.1007/s00125-010-1730-z;
     
  8. Jagannathan M, Hasturk H, Liang Y, Shin H, Hetzel JT, Kantarci A, Rubin D, McDonnell ME, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients. J Immunol. 2009 Dec 1; 183(11):7461-70.View Related Profiles. PMID: 19917698; PMCID: PMC2851147; DOI: 10.4049/jimmunol.0901517;
     
  9. Noronha AM, Liang Y, Hetzel JT, Hasturk H, Kantarci A, Stucchi A, Zhang Y, Nikolajczyk BS, Farraye FA, Ganley-Leal LM. Hyperactivated B cells in human inflammatory bowel disease. J Leukoc Biol. 2009 Oct; 86(4):1007-16.View Related Profiles. PMID: 19589946; PMCID: PMC2796625; DOI: 10.1189/jlb.0309203;
     

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