Kimberly Leite-Morris | Profiles RNS

Kimberly Leite-Morris, PhD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Psychiatry

General Psychiatry

PhD, University of Rhode Island
BS, University of Rhode Island

Websites

	LinkedIn
	ResearchGate

ORCID : 0000-0003-3407-7375

Dr. Leite-Morris is an Assistant Professor in the Division of Psychiatry and Department of Pharmacology and Experimental Therapeutics at Chobanian and Avedisian School of Medicine and directs a neurochemistry and behavioral neuroscience laboratory at the VA Boston Healthcare System. Dr. Leite-Morris’ primary research interests are in determining the neurochemical mechanisms that underlie the anticipation, intense “craving” and repeated consumption of ethanol and substance abuse. She has established a rodent model of ethanol-self administration paired with current methods of in vivo microdialysis that procedurally separates and quantifies neurotransmitter levels during the different elements of the addiction process. Her methods incorporate a pharmacological approach utilizing novel therapeutic agents including novel positive allosteric modulators of the GABA receptor that culminate in alterations of dopamine, GABA and glutamate.

Dr. Leite-Morris has established a behavioral phenotyping laboratory at the VABHS to examine fear conditioning and stress as they relate to alcohol-directed behaviors in genetically modified mice.Dr. Leite-Morris’ collaborative projects include opiate reward and extinction, fear conditioning, and alcohol and substance abuse in penetrating brain injury and shock wave. Dr. Leite-Morris received her doctorate from the University of Rhode Island in the Department of Biochemisty and Molecular Genetics and completed her NIAAA NRSA Postdoctoral Fellowship at Brown University’s Center for Alcohol and Addiction Studies where she remains an Affiliate Faculty member. She is supported by a grant from NIAAA. Interested students can contact Dr. Leite-Morris at kleitemo@bu.edu.

VA Boston Healthcare System

Interpersonal Agreement for Kimberly Leite-Morris
01/01/2019 - 07/31/2019 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Kimberly Leite-Morris
10/01/2017 - 09/30/2018 (PI)
VA Boston Healthcare System

Monitor for multiple biomarkers for detection of alcohol consumption
09/15/2015 - 06/30/2018 (Subcontract PI)
Yellowstone Scientific Instruments NIH NIAAA
5R44AA022559-03

Personnel Agreement for Research Services of Dr. Kimberly Leite-Morris (Dr. Gary Kaplan)
12/01/2015 - 09/30/2017 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Dr. Kimberly Leite-Morris (Dr. Alpasian Dedegoglu)
03/01/2015 - 06/30/2017 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Kimberly Leite-Morris (Dr. Gary Kaplan)
03/01/2015 - 06/30/2015 (PI)
VA Boston Healthcare System

Personnel Agreement for Kimberly Leite-Morris
08/01/2014 - 12/31/2014 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Kimberly Leite-Morris
12/01/2011 - 12/31/2014 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Kimberly Leite-Morris
09/15/2013 - 09/14/2014 (PI)
VA Boston Healthcare System

Personnel agreement for research services of Kimberly Leite-Morris
11/01/2012 - 09/14/2014 (PI)
VA Boston Healthcare System

Showing 10 of 12 results. Show All Results

Title
Monitor for Multiple Biomarkers or Detection of Alcohol Consumption (PI)

Yr	Title	Project-Sub Proj	Pubs
2009	ETHANOL SEEKING &INTAKE: MICRODIALYSIS/DA/GABA	5K01AA015194-05	1
2008	ETHANOL SEEKING &INTAKE: MICRODIALYSIS/DA/GABA	5K01AA015194-04	1
2007	ETHANOL SEEKING &INTAKE: MICRODIALYSIS/DA/GABA	5K01AA015194-03	1
2006	ETHANOL SEEKING &INTAKE: MICRODIALYSIS/DA/GABA	5K01AA015194-02	1
2005	ETHANOL SEEKING &INTAKE: MICRODIALYSIS/DA/GABA	1K01AA015194-01A1	1

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Babb JA, Zuberer A, Heinrichs S, Rumbika KK, Alfiler L, Lakis GA, Leite-Morris KA, Kaplan GB. Disturbances in fear extinction learning after mild traumatic brain injury in mice are accompanied by alterations in dendritic plasticity in the medial prefrontal cortex and basolateral nucleus of the amygdala. Brain Res Bull. 2023 Jun 15; 198:15-26.View Related Profiles.

Zuberer, Agnieszka
Lakis, Gabrielle
Kaplan, Gary
Leite-Morris, Kimberly

PMID: 37031792

Lim TC, Mandeville E, Weng D, Wang LS, Kurisawa M, Leite-Morris K, Selim MH, Lo EH, Spector M. Hydrogel-Based Therapy for Brain Repair After Intracerebral Hemorrhage. Transl Stroke Res. 2020 06; 11(3):412-417. PMID: 31432328

Carreras I, Aytan N, Mellott T, Choi JK, Lehar M, Crabtree L, Leite-Morris K, Jenkins BG, Blusztajn JK, Dedeoglu A. Corrigendum to "Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease" [Brain Res. 1681 (2018) 34-43]. Brain Res. 2018 06 01; 1688:113-115.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Blusztajn, Jan
Leite-Morris, Kimberly
Aytan, Nurgul
Mellott, Tiffany

PMID: 29526415

Carreras I, Aytan N, Mellott T, Choi JK, Lehar M, Crabtree L, Leite-Morris K, Jenkins BG, Blusztajn JK, Dedeoglu A. Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease. Brain Res. 2018 02 15; 1681:34-43.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Blusztajn, Jan
Leite-Morris, Kimberly
Aytan, Nurgul
Mellott, Tiffany

PMID: 29277710; PMCID: PMC5971846; DOI: 10.1016/j.brainres.2017.12.030;

Kaplan GB, Leite-Morris KA, Wang L, Rumbika KK, Heinrichs SC, Zeng X, Wu L, Arena DT, Teng YD. Pathophysiological Bases of Comorbidity: Traumatic Brain Injury and Post-Traumatic Stress Disorder. J Neurotrauma. 2018 01 15; 35(2):210-225.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 29017388

Maccioni P, Lorrai I, Contini A, Leite-Morris K, Colombo G. Microinjection of baclofen and CGP7930 into the ventral tegmental area suppresses alcohol self-administration in alcohol-preferring rats. Neuropharmacology. 2018 07 01; 136(Pt A):146-158. PMID: 29050951

Maccioni P, Vargiolu D, Thomas AW, Malherbe P, Mugnaini C, Corelli F, Leite-Morris KA, Gessa GL, Colombo G. Inhibition of alcohol self-administration by positive allosteric modulators of the GABAB receptor in rats: lack of tolerance and potentiation of baclofen. Psychopharmacology (Berl). 2015 May; 232(10):1831-41. PMID: 25420609; DOI: 10.1007/s00213-014-3815-8;

Leite-Morris KA, Kobrin KL, Guy MD, Young AJ, Heinrichs SC, Kaplan GB. Extinction of opiate reward reduces dendritic arborization and c-Fos expression in the nucleus accumbens core. Behav Brain Res. 2014 Apr 15; 263:51-9.View Related Profiles.

Kaplan, Gary
Kobrin, Kendra
Leite-Morris, Kimberly
Guy, Marsha

PMID: 24406724; DOI: 10.1016/j.bbr.2013.12.041;

Heinrichs SC, Leite-Morris KA, Rasmusson AM, Kaplan GB. Repeated valproate treatment facilitates fear extinction under specific stimulus conditions. Neurosci Lett. 2013 Sep 27; 552:108-13.View Related Profiles.

Rasmusson, Ann
Kaplan, Gary
Leite-Morris, Kimberly

PMID: 23916657; DOI: 10.1016/j.neulet.2013.07.035;

Heinrichs SC, Leite-Morris KA, Guy MD, Goldberg LR, Young AJ, Kaplan GB. Dendritic structural plasticity in the basolateral amygdala after fear conditioning and its extinction in mice. Behav Brain Res. 2013 Jul 1; 248:80-4.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly
Goldberg, Lisa
Guy, Marsha

PMID: 23570859; PMCID: PMC4438560; DOI: 10.1016/j.bbr.2013.03.048;

Showing 10 of 29 results. Show More

Nic Dhonnchadha BÁ, Lin A, Leite-Morris KA, Kaplan GB, Man HY, Kantak KM. Alterations in expression and phosphorylation of GluA1 receptors following cocaine-cue extinction learning. Behav Brain Res. 2013 Feb 1; 238:119-23.View Related Profiles.

Kaplan, Gary
Kantak, Kathleen
Leite-Morris, Kimberly

PMID: 23085477; PMCID: PMC3542979; DOI: 10.1016/j.bbr.2012.10.012;

Nic Dhonnchadha BÁ, Lovascio BF, Shrestha N, Lin A, Leite-Morris KA, Man HY, Kaplan GB, Kantak KM. Changes in expression of c-Fos protein following cocaine-cue extinction learning. Behav Brain Res. 2012 Sep 1; 234(1):100-6.View Related Profiles.

Kaplan, Gary
Kantak, Kathleen
Leite-Morris, Kimberly

PMID: 22721675; PMCID: PMC3412160; DOI: 10.1016/j.bbr.2012.06.010;

Fitzgerald DM, Charness ME, Leite-Morris KA, Chen S. Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1. PLoS One. 2011; 6(9):e24364.View Related Profiles.

Leite-Morris, Kimberly
Charness, Michael

PMID: 21931691; PMCID: PMC3169602; DOI: 10.1371/journal.pone.0024364;

Kaplan GB, Leite-Morris KA, Fan W, Young AJ, Guy MD. Opiate sensitization induces FosB/?FosB expression in prefrontal cortical, striatal and amygdala brain regions. PLoS One. 2011; 6(8):e23574.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly
Guy, Marsha

PMID: 21886798; PMCID: PMC3160315; DOI: 10.1371/journal.pone.0023574;

Heinrichs SC, Leite-Morris KA, Carey RJ, Kaplan GB. Baclofen enhances extinction of opiate conditioned place preference. Behav Brain Res. 2010 Mar 5; 207(2):353-9.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 19840820; DOI: 10.1016/j.bbr.2009.10.013;

Maccioni P, Carai MA, Kaupmann K, Guery S, Froestl W, Leite-Morris KA, Gessa GL, Colombo G. Reduction of alcohol's reinforcing and motivational properties by the positive allosteric modulator of the GABA(B) receptor, BHF177, in alcohol-preferring rats. Alcohol Clin Exp Res. 2009 Oct; 33(10):1749-56. PMID: 19572981; DOI: 10.1111/j.1530-0277.2009.01012.x;

Kaplan GB, Leite-Morris KA, Klufas MA, Fan W. Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity. Eur J Pharmacol. 2009 Jan 14; 602(2-3):268-76.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 19027733; DOI: 10.1016/j.ejphar.2008.10.052;

Turalba AV, Leite-Morris KA, Kaplan GB. Antipsychotics regulate cyclic AMP-dependent protein kinase and phosphorylated cyclic AMP response element-binding protein in striatal and cortical brain regions in mice. Neurosci Lett. 2004 Feb 26; 357(1):53-7.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 15036612

Leite-Morris KA, Fukudome EY, Shoeb MH, Kaplan GB. GABA(B) receptor activation in the ventral tegmental area inhibits the acquisition and expression of opiate-induced motor sensitization. J Pharmacol Exp Ther. 2004 Feb; 308(2):667-78.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 14610238

Kaplan GB, Leite-Morris KA, Joshi M, Shoeb MH, Carey RJ. Baclofen inhibits opiate-induced conditioned place preference and associated induction of Fos in cortical and limbic regions. Brain Res. 2003 Oct 10; 987(1):122-5.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 14499954

Leite-Morris KA, Fukudome EY, Kaplan GB. Opiate-induced motor stimulation is regulated by gamma-aminobutyric acid type B receptors found in the ventral tegmental area in mice. Neurosci Lett. 2002 Jan 14; 317(3):119-22.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 11755254

Kaplan GB, Leite-Morris KA, Keith DJ. Differential effects of treatment with typical and atypical antipsychotic drugs on adenylyl cyclase and G proteins. Neurosci Lett. 1999 Oct 8; 273(3):147-50.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 10515180

Kaplan GB, Bharmal NH, Leite-Morris KA, Adams WR. Role of adenosine A1 and A2A receptors in the alcohol withdrawal syndrome. Alcohol. 1999 Oct; 19(2):157-62.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 10548160

Leite-Morris KA, Kaplan GB, Smith JG, Sears MT. Regulation of G proteins and adenylyl cyclase in brain regions of caffeine-tolerant and -dependent mice. Brain Res. 1998 Aug 31; 804(1):52-62.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 9729274

Kaplan GB, Sethi RK, McClelland EG, Leite-Morris KA. Regulation of G protein-mediated adenylyl cyclase in striatum and cortex of opiate-dependent and opiate withdrawing mice. Brain Res. 1998 Mar 30; 788(1-2):104-10.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 9554971

Kaplan GB, Leite-Morris KA. Up-regulation of adenosine transporter-binding sites in striatum and hypothalamus of opiate tolerant mice. Brain Res. 1997 Jul 25; 763(2):215-20.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 9296562

Kaplan GB, Leite-Morris KA, Sears MT. Alterations of adenosine A1 receptors in morphine dependence. Brain Res. 1994 Sep 19; 657(1-2):347-50.View Related Profiles.

Kaplan, Gary
Leite-Morris, Kimberly

PMID: 7820640

Su HC, Leite-Morris KA, Braun L, Biron CA. A role for transforming growth factor-beta 1 in regulating natural killer cell and T lymphocyte proliferative responses during acute infection with lymphocytic choriomeningitis virus. J Immunol. 1991 Oct 15; 147(8):2717-27. PMID: 1918986

Kasaian MT, Leite-Morris KA, Biron CA. The role of CD4+ cells in sustaining lymphocyte proliferation during lymphocytic choriomeningitis virus infection. J Immunol. 1991 Mar 15; 146(6):1955-63. PMID: 1672337

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 29 publications over 18 distinct years, with a maximum of 3 publications in 2017