Joseph Lykins

Assistant Professor

Boston Medical Center

Emergency Medicine

MD, Pritzker School of Medicine
BS, University of Oklahoma

Websites

Publications
Contact Info

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Simpson B, Han K, Yee S, Alsaadawi R, Sabo R, Aurora T, Lykins J. Factors Associated With Observation Unit Admission in Emergency Department Patients With Skin and Soft Tissue Infections. J Am Coll Emerg Physicians Open. 2025 Feb; 6(1):100002. PMID: 40012661; PMCID: PMC11852664; DOI: 10.1016/j.acepjo.2024.100002;

Van Besien A, Mauricio IP, Belfort R, Lykins J. Case Report of HIV and Neurosyphilis Coinfection in a Recent Migrant: Old Diseases in New Faces. Clin Pract Cases Emerg Med. 2025 Jan; 9(1):28-32. PMID: 39903617

Simpson B, Han K, Yee S, Alsaadawi R, Sabo R, Aurora T, Lykins J. Factors associated with emergency department methicillin-resistant Staphylococcus aureus coverage in patients with skin and soft tissue infections in an urban, tertiary care emergency department. Am J Emerg Med. 2025 Feb; 88:49-56. PMID: 39591803

Zhou Y, Leahy K, Grose A, Lykins J, Siddiqui M, Leong N, Goodall P, Withers S, Ashi K, Schrantz S, Tesic V, Abeleda AP, Beavis K, Clouser F, Ismail M, Christmas M, Piarroux R, Limonne D, Chapey E, Abraham S, Baird I, Thibodeau J, Boyer KM, Torres E, Conrey S, Wang K, Staat MA, Back N, L'Ollivier C, Mahinc C, Flori P, Gomez-Marin J, Peyron F, Houzé S, Wallon M, McLeod R. Novel paradigm enables accurate monthly gestational screening to prevent congenital toxoplasmosis and more. PLoS Negl Trop Dis. 2024 May; 18(5):e0011335. PMID: 38805559; PMCID: PMC11132520; DOI: 10.1371/journal.pntd.0011335;

Lykins J, Moschitto MJ, Zhou Y, Filippova EV, Le HV, Tomita T, Fox BA, Bzik DJ, Su C, Rajagopala SV, Flores K, Spano F, Woods S, Roberts CW, Hua C, El Bissati K, Wheeler KM, Dovgin S, Muench SP, McPhillie M, Fishwick CWG, Anderson WF, Lee PJ, Hickman M, Weiss LM, Dubey JP, Lorenzi HA, Silverman RB, McLeod RL. From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma. iScience. 2024 Jan 19; 27(1):108477. PMID: 38205261; PMCID: PMC10776954; DOI: 10.1016/j.isci.2023.108477;

El Bissati K, Krishack PA, Zhou Y, Weber CR, Lykins J, Jankovic D, Edelblum KL, Fraczek L, Grover H, Chentoufi AA, Singh G, Reardon C, Dubey JP, Reed S, Alexander J, Sidney J, Sette A, Shastri N, McLeod R. CD4+ T Cell Responses to Toxoplasma gondii Are a Double-Edged Sword. Vaccines (Basel). 2023 Sep 14; 11(9). PMID: 37766162; PMCID: PMC10535856; DOI: 10.3390/vaccines11091485;

Kuttab HI, Evans CG, Lykins JD, Hughes MD, Kopec JA, Hernandez MA, Ward MA. The Effect of Fluid Resuscitation Timing in Early Sepsis Resuscitation. J Intensive Care Med. 2023 Nov; 38(11):1051-1059. PMID: 37287235

Goggins A, Lykins J, Aston A, Shaw J. Acute cholecystitis secondary to Raoultella ornithinolytica infection, complicated by sepsis, gallbladder perforation, hepatic abscess and bacteraemia. BMJ Case Rep. 2022 Dec 29; 15(12). PMID: 36581355; PMCID: PMC9806088; DOI: 10.1136/bcr-2022-250766;

Felín MS, Wang K, Moreira A, Grose A, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Caballero Z, Norero X, Estripeaut D, Ellis D, Raggi C, Castro C, Moossazadeh D, Ramirez M, Pandey A, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Villalobos-Cerrud D, Fabrega L, Montalvo JLS, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de Guevara ML, Flores C, Borace J, García A, Caballero N, Rengifo-Herrera C, de Saez MTM, Politis M, Wroblewski K, Karrison T, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Restrepo CM, Llanes A, Guzman G, Rebellon A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Ramirez M, Chittenden C, Wang E, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Padrieu G, Hernandez JDV, Celis-Giraldo D, Dávila JAA, Torres E, Oquendo MM, Arteaga-Rivera JY, Nicolae DL, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Holfels E, Frim D, McLone D, Penn R, Cohen W, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Meier P, Grigg M, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part I: Introduction and Overview. Curr Pediatr Rep. 2022; 10(3):57-92. PMID: 36034212; PMCID: PMC9395898; DOI: 10.1007/s40124-022-00269-w;

Felín MS, Wang K, Moreira A, Grose A, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Caballero Z, Norero X, Estripeaut D, Ellis D, Raggi C, Castro C, Moossazadeh D, Ramirez M, Pandey A, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Villalobos-Cerrud D, Fabrega L, Montalvo JLS, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de Guevara ML, Flores C, Borace J, García A, Caballero N, Rengifo-Herrera C, de Saez MTM, Politis M, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Restrepo CM, Llanes A, Guzman G, Rebellon A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Frim D, McLone D, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Ramirez M, Chittenden C, Wang E, Garcia-López LL, Padrieu G, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Hernandez JDV, Celis-Giraldo D, Dávila JAA, Torres E, Oquendo MM, Arteaga-Rivera JY, Nicolae DL, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, Holfels E, Frim D, McLone D, Penn R, Cohen W, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Meier P, Grigg M, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part IV: Understanding and Development of Public Health Strategies and Advances "Take a Village". Curr Pediatr Rep. 2022; 10(3):125-154. PMID: 35991908; PMCID: PMC9379243; DOI: 10.1007/s40124-022-00268-x;

Showing 10 of 29 results. Show More

Felín MS, Wang K, Moreira A, Grose A, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Caballero Z, Norero X, Estripeaut D, Ellis D, Raggi C, Castro C, Rengifo-Herrera C, Moossazadeh D, Ramirez M, Pandey A, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Villalobos-Cerrud D, Fabrega L, Montalvo JLS, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de Guevara ML, Flores C, Borace J, García A, Caballero N, de Saez MTM, Politis M, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Restrepo CM, Llanes A, Guzman G, Rebellon A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Frim D, McLone D, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Ramirez M, Chittenden C, Wang E, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Padrieu G, Hernandez JDV, Celis-Giraldo D, Dávila JAA, Torres E, Oquendo MM, Arteaga-Rivera JY, Nicolae DL, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, Holfels E, Penn R, Cohen W, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Meier P, Grigg M, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part II: Education. Curr Pediatr Rep. 2022 Sep; 10(3):93-108. PMID: 36969368; PMCID: PMC10035399; DOI: 10.1007/s40124-022-00267-y;

Felín MS, Wang K, Raggi C, Moreira A, Pandey A, Grose A, Caballero Z, Rengifo-Herrera C, Ramirez M, Moossazadeh D, Castro C, Montalvo JLS, Leahy K, Zhou Y, Clouser FA, Siddiqui M, Leong N, Goodall P, Michalowski M, Ismail M, Christmas M, Schrantz S, Norero X, Estripeaut D, Ellis D, Ashi K, Dovgin S, Dixon A, Li X, Begeman I, Heichman S, Lykins J, Villalobos-Cerrud D, Fabrega L, Mendivil C, Quijada MR, Fernández-Pirla S, de La Guardia V, Wong D, de LadrónGuevara M, Flores C, Borace J, García A, Caballero N, de Saez MTM, Politis M, Ross S, Dogra M, Dhamsania V, Graves N, Kirchberg M, Mathur K, Aue A, Restrepo CM, Llanes A, Guzman G, Rebollon A, Boyer K, Heydemann P, Noble AG, Swisher C, Rabiah P, Withers S, Hull T, Su C, Blair M, Latkany P, Mui E, Vasconcelos-Santos DV, Villareal A, Perez A, Galvis CAN, Montes MV, Perez NIC, Ramirez M, Chittenden C, Wang E, Garcia-López LL, Muñoz-Ortiz J, Rivera-Valdivia N, Bohorquez-Granados MC, de-la-Torre GC, Padrieu G, Hernandez JDV, Celis-Giraldo D, Acosta Dávila JA, Torres E, Oquendo MM, Arteaga-Rivera JY, Nicolae D, Rzhetsky A, Roizen N, Stillwaggon E, Sawers L, Peyron F, Wallon M, Chapey E, Levigne P, Charter C, De Frias M, Montoya J, Press C, Ramirez R, Contopoulos-Ioannidis D, Maldonado Y, Liesenfeld O, Gomez C, Wheeler K, Holfels E, Frim D, McLone D, Penn R, Cohen W, Zehar S, McAuley J, Limonne D, Houze S, Abraham S, Piarroux R, Tesic V, Beavis K, Abeleda A, Sautter M, El Mansouri B, El Bachir A, Amarir F, El Bissati K, de-la-Torre A, Britton G, Motta J, Ortega-Barria E, Romero IL, Meier P, Grigg M, Gómez-Marín J, Kosagisharaf JR, Llorens XS, Reyes O, McLeod R. Building Programs to Eradicate Toxoplasmosis Part III: Epidemiology and Risk Factors. Curr Pediatr Rep. 2022 Sep; 10(3):109-124. PMID: 37744780; PMCID: PMC10516319; DOI: 10.1007/s40124-022-00265-0;

El Mansouri B, Amarir F, Peyron F, Adlaoui EB, Piarroux R, Lykins J, El Abbassi M, Nekkal N, Bouhlal N, Makkaoui K, Barkat A, Lyaghfouri A, Zhou Y, Rais S, Oudghiri M, Elkoraichi I, Zekri M, Belkadi N, Mellouk H, Rhajaoui M, Boutajangout A, Sadak A, Limonne D, McLeod R, El Bissati K. High performance of a novel point-of-care blood test for Toxoplasma infection in women from diverse regions of Morocco. Emerg Microbes Infect. 2021 Dec; 10(1):1675-1682. PMID: 34165384; PMCID: PMC8381951; DOI: 10.1080/22221751.2021.1948359;

Rourke EM, Kuttab HI, Lykins JD, Hughes MD, Keast EP, Kopec JA, Wroblewski K, Purakal J, Ward MA. Fluid Resuscitation in Septic Patients With Comorbid Heart Failure. Crit Care Med. 2021 Feb 01; 49(2):e201-e204. PMID: 33438983; PMCID: PMC7810156; DOI: 10.1097/CCM.0000000000004730;

Leffler CT, Ing E, Lykins JD, Hogan MC, McKeown CA, Grzybowski A. Association of Country-wide Coronavirus Mortality with Demographics, Testing, Lockdowns, and Public Wearing of Masks. Am J Trop Med Hyg. 2020 Dec; 103(6):2400-2411. PMID: 33124541; PMCID: PMC7695060; DOI: 10.4269/ajtmh.20-1015;

El Bissati K, Zhou Y, Paulillo SM, Raman SK, Karch CP, Reed S, Estes A, Estes A, Lykins J, Burkhard P, McLeod R. Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice. Sci Rep. 2020 Oct 12; 10(1):16984. PMID: 33046728; PMCID: PMC7552409; DOI: 10.1038/s41598-020-73210-0;

McPhillie MJ, Zhou Y, Hickman MR, Gordon JA, Weber CR, Li Q, Lee PJ, Amporndanai K, Johnson RM, Darby H, Woods S, Li ZH, Priestley RS, Ristroph KD, Biering SB, El Bissati K, Hwang S, Hakim FE, Dovgin SM, Lykins JD, Roberts L, Hargrave K, Cong H, Sinai AP, Muench SP, Dubey JP, Prud'homme RK, Lorenzi HA, Biagini GA, Moreno SN, Roberts CW, Antonyuk SV, Fishwick CWG, McLeod R. Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites. Front Cell Infect Microbiol. 2020; 10:203. PMID: 32626661; PMCID: PMC7311950; DOI: 10.3389/fcimb.2020.00203;

McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R. Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep. 2020 Mar 23; 10(1):5512. PMID: 32251362; PMCID: PMC7089975; DOI: 10.1038/s41598-020-62323-1;

Kuttab HI, Lykins JD, Hughes MD, Wroblewski K, Keast EP, Kukoyi O, Kopec JA, Hall S, Ward MA. Evaluation and Predictors of Fluid Resuscitation in Patients With Severe Sepsis and Septic Shock. Crit Care Med. 2019 Nov; 47(11):1582-1590. PMID: 31393324; PMCID: PMC8096207; DOI: 10.1097/CCM.0000000000003960;

McLone D, Frim D, Penn R, Swisher CN, Heydemann P, Boyer KM, Noble AG, Rabiah PK, Withers S, Wroblewski K, Karrison T, Hutson S, Wheeler K, Cohen W, Lykins J, McLeod R. Outcomes of hydrocephalus secondary to congenital toxoplasmosis. J Neurosurg Pediatr. 2019 Sep 06; 24(5):601-608. PMID: 31491752

El Bissati K, Redel H, Ting LM, Lykins JD, McPhillie MJ, Upadhya R, Woster PM, Yarlett N, Kim K, Weiss LM. Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations. Front Cell Infect Microbiol. 2019; 9:9. PMID: 30838177; PMCID: PMC6382690; DOI: 10.3389/fcimb.2019.00009;

Lykins JD, Filippova EV, Halavaty AS, Minasov G, Zhou Y, Dubrovska I, Flores KJ, Shuvalova LA, Ruan J, El Bissati K, Dovgin S, Roberts CW, Woods S, Moulton JD, Moulton H, McPhillie MJ, Muench SP, Fishwick CWG, Sabini E, Shanmugam D, Roos DS, McLeod R, Anderson WF, Ngô HM. CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. Front Cell Infect Microbiol. 2018; 8:352. PMID: 30345257

El Bissati K, Levigne P, Lykins J, Adlaoui EB, Barkat A, Berraho A, Laboudi M, El Mansouri B, Ibrahimi A, Rhajaoui M, Quinn F, Murugesan M, Seghrouchni F, Gómez-Marín JE, Peyron F, McLeod R. Global initiative for congenital toxoplasmosis: an observational and international comparative clinical analysis. Emerg Microbes Infect. 2018 Sep 27; 7(1):165. PMID: 30262847; PMCID: PMC6160433; DOI: 10.1038/s41426-018-0164-4;

Lykins J, Li X, Levigne P, Zhou Y, El Bissati K, Clouser F, Wallon M, Morel F, Leahy K, El Mansouri B, Siddiqui M, Leong N, Michalowski M, Irwin E, Goodall P, Ismail M, Christmas M, Adlaoui EB, Rhajaoui M, Barkat A, Cong H, Begeman IJ, Lai BS, Contopoulos-Ioannidis DG, Montoya JG, Maldonado Y, Ramirez R, Press C, Peyron F, McLeod R. Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies. PLoS Negl Trop Dis. 2018 Aug; 12(8):e0006536. PMID: 30114251

Begeman IJ, Lykins J, Zhou Y, Lai BS, Levigne P, El Bissati K, Boyer K, Withers S, Clouser F, Noble AG, Rabiah P, Swisher CN, Heydemann PT, Contopoulos-Ioannidis DG, Montoya JG, Maldonado Y, Ramirez R, Press C, Stillwaggon E, Peyron F, McLeod R. Point-of-care testing for Toxoplasma gondii IgG/IgM using Toxoplasma ICT IgG-IgM test with sera from the United States and implications for developing countries. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005670. PMID: 28650970

El Bissati K, Chentoufi AA, Krishack PA, Zhou Y, Woods S, Dubey JP, Vang L, Lykins J, Broderick KE, Mui E, Suzuki Y, Sa Q, Bi S, Cardona N, Verma SK, Fraczek L, Reardon CA, Sidney J, Alexander J, Sette A, Vedvick T, Fox C, Guderian JA, Reed S, Roberts CW, McLeod R. Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii. JCI Insight. 2016 Sep 22; 1(15):e85955. PMID: 27699241

McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R. New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep. 2016 Jul 14; 6:29179. PMID: 27412848

Lykins J, Wang K, Wheeler K, Clouser F, Dixon A, El Bissati K, Zhou Y, Lyttle C, Rzhetsky A, McLeod R. Understanding Toxoplasmosis in the United States Through "Large Data" Analyses. Clin Infect Dis. 2016 Aug 15; 63(4):468-75. PMID: 27353665

Ristic M, Lykins JD, Morris HR. Anaplasmosis: opsonins and hemagglutinins in etiology of anemia. Exp Parasitol. 1972 Feb; 31(1):2-12. PMID: 5010604

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 28 publications over 10 distinct years, with a maximum of 5 publications in 2022

Bar chart showing 28 publications over 10 distinct years, with a maximum of 5 publications in 2022

Year	Publications
2016	3
2017	1
2018	3
2019	3
2020	4
2021	2
2022	5
2023	3
2024	2
2025	2

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