Jin Wei, PhD, is an Assistant Professor of Medicine at Boston University Chobanian & Avedisian School of Medicine and a Principal Investigator in the Department of Medicine Nephrology Section. Dr. Wei received over a decade of training in cardiovascular and renal physiology at the University of Mississippi Medical Center and the University of South Florida Morsani College of Medicine, spanning his doctoral, post-doctoral, and early faculty years. During the training period, his research was supported by the American Society of Nephrology Ben J. Lipps Postdoctoral Fellowship and Carl W. Gottschalk Transition to Independence Research Scholar Grant. In 2023, Dr. Wei joined Boston University Chobanian & Avedisian School of Medicine and established his independent research laboratory in the Department of Medicine Nephrology Section. Dr. Wei’s laboratory investigates pathogenetic mechanisms and therapeutic targets in cardiovascular and renal diseases, with a particular focus on hypertension, preeclampsia and cardiorenal syndrome. His research program is supported by an NIH/NHLBI R01 grant and an American Heart Association Transformational Project Award.
Diversity, Equity, Inclusion and Accessibility
Diversity, Equity, Inclusion, & Accessibility (DEIA) are fundamental values that serve as the foundation of my lab. By fostering a DEIA environment, we strive to create a comprehensive learning experience for all lab members and ensure that everyone feels included, valued, and supported.
Throughout my academic career, I have had the opportunity to work on various projects alongside colleagues from diverse ethnic backgrounds, including individuals of Asian, African, European, and American descent. This experience has provided me with a valuable opportunity to appreciate different perspectives, gain insights into diverse cultures and experiences, and develop a strong appreciation for the importance of diversity and inclusion in any collaborative endeavor. Working with colleagues from different ethnic backgrounds has broadened my horizons, and I have come to appreciate the value of diverse perspectives, which have enhanced my problem-solving abilities and my overall approach to research.
In my lab, we are dedicated to promoting DEIA principles. My lab is committed to providing equal research opportunities to postdocs, graduate students, and undergraduates from diverse backgrounds, including but not limited to race, ethnicity, gender, and ability status. I will create a safe and respectful work environment to establish ground rules and expectations for your lab culture that prioritize respect, kindness, and inclusivity, encourage open communication, active listening, and empathy among lab members, and set up mechanisms for addressing conflict or concerns, such as regular check-ins or anonymous feedback mechanisms. I will also provide opportunities for professional development and advancement and Eesure that lab members have access to the resources and support they need to succeed in their research, including funding, mentorship, training opportunities, and access to research equipment and technology. In addition, I will encourage lab members to work together, share ideas, and support each other's work. Create opportunities for group brainstorming sessions or team-building activities. Finally, we will attend conferences and events that prioritize diversity and inclusion and collaborate with researchers and organizations that are working to advance DEI in my field.
This tab shows grant data from BMC Sponsored Research. It includes:
- Grant title
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- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from BU Sponsored Research. It includes:
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data that did not automatically get imported into Profiles
from BU or BMC sources.
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from the Boston VA. We are only showing grant title, and only for people in the role of PI.
Account Macula Densa RXFP1, A New Player in Regulating Renal Hemodynamics and Systemic Blood Pressure during Pregnancy07/01/2024 - 06/30/2027 (PI)
American Heart Association/AHA
Identification of a mechanosensor in juxtaglomerular cells for the regulation of renin synthesis and secretion01/15/2024 - 12/31/2025 (PI)
National Heart, Lung, and Blood Institute/NIH/DHHS
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
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Li M, Bahena Lopez J, Ni R, Wei J, Dhanireddy K, Subramanian V, Wang L, Williams K, Hall N, Zheleznova NN, Lu Y, Fu L, Lai E, Zhang J, McCormick JA, Liu R. Macula densa-specific NOS1 knockout determines susceptibility to ischemic acute kidney injury. Clin Sci (Lond). 2026 Apr 15; 140(4):589-605. PMID: 41837645; DOI: 10.1042/CS20258807;
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Fei L, Wang X, Kong L, Cui T, Khedkar PH, Xiang Y, Zhao D, Fang J, Liang Y, Zhang Y, Xu N, Qiu X, Zhao L, Zhang G, Lei Y, Tang C, Ma K, Lu L, Wei J, Lai EY, Persson PB, Patzak A, Zheng Z, Jiang S. Tacrolimus Induced Hypertension and Vascular Remodeling Includes Mechanisms of Cellular Senescence-The Protective Effect of Valsartan. Acta Physiol (Oxf). 2026 Apr; 242(4):e70189. PMID: 41814130; PMCID: PMC12979711; DOI: 10.1111/apha.70189;
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Medak KD, Koehler JA, Baggio LL, Gonzalez-Rellan MJ, Wong CK, Cao X, Rao V, Kao S, Cui Y, Fu J, Liaw E, Kabir MG, Zhang J, Wei J, Drucker DJ. Semaglutide Reduces Murine Blood Pressure Through the Vascular Smooth Muscle GLP-1 Receptor. JCI Insight. 2026 Mar 03. PMID: 41774502
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Solomon M, Heydarpour M, Tsai LC, Honzel B, Brown JM, Newman AJ, Parisien-La Salle S, Wang TJ, Wei J, Zhang J, Waikar SS, Vaidya A. The Impact of Modern Industrialized Dietary Sodium Intake on the Plasma Proteome. Am J Hypertens. 2026 Feb 01; 39(2):280-292.View Related Profiles. PMID: 40327765
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Fei L, Wang H, Zhao D, Wang X, Ren J, Liu L, Tang C, Lei Y, Wang Q, Nie Y, Liu Y, Li N, Zhong M, Xu N, Wei J, Persson PB, Patzak A, Khedkar PH, Zheng Z, Jiang S. Rescuing vascular dysfunction in dorsal pancreatic arteries prevents tacrolimus-induced glucose metabolism disorder in mice. Mol Med. 2025 Jun 11; 31(1):230. PMID: 40495121; PMCID: PMC12153204; DOI: 10.1186/s10020-025-01282-7;
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Zheleznova NN, Sun C, Patel N, Hall N, Williams KM, Zhang J, Wei J, Xiang L, Patel R, Soni S, Sheth D, Lai E, Qiu X, Hernandez Soto N, Liu R. Comparison of Different Animal Models in Hindlimb Functional Recovery after Acute Limb Ischemia-Reperfusion Injury. Biomedicines. 2024 Sep 12; 12(9). PMID: 39335593; PMCID: PMC11428748; DOI: 10.3390/biomedicines12092079;
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Iglesias M, Wang H, Krause-Hauch M, Ren D, Zoungrana LI, Li Z, Zhang J, Wei J, Yadav N, Patel K, Fatmi MK, Liu R, Lesnefsky EJ, Li J. Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3. Cells. 2023 Mar 08; 12(6).View Related Profiles. PMID: 36980186; PMCID: PMC10047033; DOI: 10.3390/cells12060845;
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Liu R, Juncos LA, Lu Y, Wei J, Zhang J, Wang L, Lai EY, Carlstrom M, Persson AEG. The Role of Macula Densa Nitric Oxide Synthase 1 Beta Splice Variant in Modulating Tubuloglomerular Feedback. Compr Physiol. 2023 Jan 30; 13(1):4215-4229.View Related Profiles. PMID: 36715280; PMCID: PMC9990375; DOI: 10.1002/cphy.c210043;
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Chen W, Wang L, Liang P, Mast J, Mathis C, Liu CY, Wei J, Zhang J, Fu L, Juncos LA, Buggs J, Liu R. Reducing ischemic kidney injury through application of a synchronization modulation electric field to maintain Na+/K+-ATPase functions. Sci Transl Med. 2022 Mar 09; 14(635):eabj4906.View Related Profiles. PMID: 35263146; PMCID: PMC9994383; DOI: 10.1126/scitranslmed.abj4906;
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Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration. Kidney Int. 2022 Mar; 101(3):541-550.View Related Profiles. PMID: 34843754; PMCID: PMC8863629; DOI: 10.1016/j.kint.2021.10.037;
Showing 10 of 39 results.
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Zhang J, Wang X, Cui Y, Jiang S, Wei J, Chan J, Thalakola A, Le T, Xu L, Zhao L, Wang L, Jiang K, Cheng F, Patel T, Buggs J, Vallon V, Liu R. Knockout of Macula Densa Neuronal Nitric Oxide Synthase Increases Blood Pressure in db/db Mice. Hypertension. 2021 Dec; 78(6):1760-1770.View Related Profiles. PMID: 34657443; PMCID: PMC8651058; DOI: 10.1161/HYPERTENSIONAHA.121.17643;
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Wei J, Zhang J, Jiang S, Xu L, Qu L, Pang B, Jiang K, Wang L, Intapad S, Buggs J, Cheng F, Mohapatra S, Juncos LA, Osborn JL, Granger JP, Liu R. Macula Densa NOS1ß Modulates Renal Hemodynamics and Blood Pressure during Pregnancy: Role in Gestational Hypertension. J Am Soc Nephrol. 2021 Oct; 32(10):2485-2500.View Related Profiles. PMID: 34127535; PMCID: PMC8722793; DOI: 10.1681/ASN.2020070969;
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Zhang J, Qu L, Wei J, Jiang S, Xu L, Wang L, Cheng F, Jiang K, Buggs J, Liu R. A new mechanism for the sex differences in angiotensin II-induced hypertension: the role of macula densa NOS1ß-mediated tubuloglomerular feedback. Am J Physiol Renal Physiol. 2020 Nov 01; 319(5):F908-F919.View Related Profiles. PMID: 33044868; PMCID: PMC7789980; DOI: 10.1152/ajprenal.00312.2020;
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Zhang J, Wang X, Wei J, Wang L, Jiang S, Xu L, Qu L, Yang K, Fu L, Buggs J, Cheng F, Liu R. A two-stage bilateral ischemia-reperfusion injury-induced AKI to CKD transition model in mice. Am J Physiol Renal Physiol. 2020 Aug 01; 319(2):F304-F311. PMID: 32567350; PMCID: PMC7528400; DOI: 10.1152/ajprenal.00017.2020;
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Zhang J, Zhu J, Wei J, Jiang S, Xu L, Qu L, Yang K, Wang L, Buggs J, Cheng F, Tan X, Liu R. New Mechanism for the Sex Differences in Salt-Sensitive Hypertension: The Role of Macula Densa NOS1ß-Mediated Tubuloglomerular Feedback. Hypertension. 2020 Feb; 75(2):449-457.View Related Profiles. PMID: 31865794; PMCID: PMC7015450; DOI: 10.1161/HYPERTENSIONAHA.119.13822;
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Jiang S, Wang X, Wei J, Zhang G, Zhang J, Xie P, Xu L, Wang L, Zhao L, Li L, Wilcox CS, Chen J, Lai EY, Liu R. NaHCO3 Dilates Mouse Afferent Arteriole Via Na+/HCO3- Cotransporters NBCs. Hypertension. 2019 Nov; 74(5):1104-1112.View Related Profiles. PMID: 31522618; PMCID: PMC6785401; DOI: 10.1161/HYPERTENSIONAHA.119.13235;
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Zhang J, Wei J, Jiang S, Xu L, Wang L, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia. J Am Soc Nephrol. 2019 Apr; 30(4):578-593.View Related Profiles. PMID: 30867247; PMCID: PMC6442354; DOI: 10.1681/ASN.2018080844;
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Zhang J, Qu HY, Song J, Wei J, Jiang S, Wang L, Wang L, Buggs J, Liu R. Enhanced hemodynamic responses to angiotensin II in diabetes are associated with increased expression and activity of AT1 receptors in the afferent arteriole. Physiol Genomics. 2017 Oct 01; 49(10):531-540.View Related Profiles. PMID: 28842434; PMCID: PMC5668650; DOI: 10.1152/physiolgenomics.00025.2017;
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Wang L, Song J, Wang S, Buggs J, Chen R, Zhang J, Wang L, Rong S, Li W, Wei J, Liu R. Cross-sex transplantation alters gene expression and enhances inflammatory response in the transplanted kidneys. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F326-F338.View Related Profiles. PMID: 28515172; PMCID: PMC5582902; DOI: 10.1152/ajprenal.00039.2017;
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Wei J, Song J, Jiang S, Zhang G, Wheeler D, Zhang J, Wang S, Lai EY, Wang L, Buggs J, Liu R. Role of intratubular pressure during the ischemic phase in acute kidney injury. Am J Physiol Renal Physiol. 2017 Jun 01; 312(6):F1158-F1165.View Related Profiles. PMID: 28579560; PMCID: PMC6148315; DOI: 10.1152/ajprenal.00527.2016;
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Lu Y, Wei J, Stec DE, Roman RJ, Ge Y, Cheng L, Liu EY, Zhang J, Hansen PB, Fan F, Juncos LA, Wang L, Pollock J, Huang PL, Fu Y, Wang S, Liu R. Macula Densa Nitric Oxide Synthase 1ß Protects against Salt-Sensitive Hypertension. J Am Soc Nephrol. 2016 Aug; 27(8):2346-56.View Related Profiles. PMID: 26647426; PMCID: PMC4978040; DOI: 10.1681/ASN.2015050515;
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Wang L, Shen C, Liu H, Wang S, Chen X, Roman RJ, Juncos LA, Lu Y, Wei J, Zhang J, Yip KP, Liu R. Shear stress blunts tubuloglomerular feedback partially mediated by primary cilia and nitric oxide at the macula densa. Am J Physiol Regul Integr Comp Physiol. 2015 Oct; 309(7):R757-66.View Related Profiles. PMID: 26269519; PMCID: PMC4666931; DOI: 10.1152/ajpregu.00173.2015;
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Lu Y, Zhang R, Ge Y, Carlstrom M, Wang S, Fu Y, Cheng L, Wei J, Roman RJ, Wang L, Gao X, Liu R. Identification and function of adenosine A3 receptor in afferent arterioles. Am J Physiol Renal Physiol. 2015 May 01; 308(9):F1020-5. PMID: 25608966; PMCID: PMC4420990; DOI: 10.1152/ajprenal.00422.2014;
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Song J, Lu Y, Lai EY, Wei J, Wang L, Chandrashekar K, Wang S, Shen C, Juncos LA, Liu R. Oxidative status in the macula densa modulates tubuloglomerular feedback responsiveness in angiotensin II-induced hypertension. Acta Physiol (Oxf). 2015 Jan; 213(1):249-58. PMID: 25089004; PMCID: PMC4389650; DOI: 10.1111/apha.12358;
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This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
| Year | Publications |
|---|
| 2013 | 1 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 3 |
| 2017 | 6 |
| 2018 | 3 |
| 2019 | 8 |
| 2020 | 2 |
| 2021 | 3 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 1 |
| 2026 | 4 |
2022 American Physiological Society / American Society of Nephrology Conference:
Poster Award
2020 Annual Nephrology Young Investigators’ Forum of Southern Society for Clinical Investigation:
First Place Award
2020-2022 American Society of Nephrology:
Carl W. Gottschalk Research Transition to Independence Grant
2019 Experimental Biology Meeting:
Postdoctoral Excellence in Research Award Finalist
2019 American Physiological Society / American Society of Nephrology Conference:
Travel Award
2019 American Heart Association Council of Hypertension:
Early Career Oral Presentation Award
2018 Annual Nephrology Young Investigators’ Forum of Southern Society for Clinical Investigation:
Second Place Award
2018 American Heart Association Council of Hypertension:
Trainee Poster Presentation Award
2018-2020 American Society of Nephrology:
Ben J. Lipps Research Post-Doctoral Fellowship
2017 American Heart Association Council of Hypertension:
New Investigator Travel Award
2016 American Heart Association Council of Hypertension:
Trainee Poster Presentation Award