James Hamilton | Profiles RNS

James A. Hamilton, PhD

Professor

Boston University Chobanian & Avedisian School of Medicine

Pharmacology, Physiology & Biophysics

PhD, Indiana University Bloomington
BS, Juniata College

Websites

	College of Engineering Faculty
	Whitaker Cardiovascular Institute Training Program
	Program in Inflammatory Disorders Faculty
	Google Scholar
	ResearchGate
	LinkedIn

ORCID : 0000-0002-4747-7071

Research in our group is aimed at providing fundamental information relating to heart disease, diabetes, obesity, and diseases related to fatty acid metabolism. An overall goal to is to develop novel approaches to biomedical issues by integrating physical-chemical and physiological/biochemical approaches. In our newer research this is achieved by assembling multi-disciplinary teams to translate basic research into clinical applications. We use physical and instrumental methods (including solution state 13C NMR spectroscopy, solid state and magic angle spinning multinuclear NMR, multidimensional NMR, MR imaging, and fluorescence) that are tailored to the specific questions we are addressing. These techniques are complemented with molecular modeling, molecular biology and other cell biology methods.

Professor
Boston University Chobanian & Avedisian School of Medicine
Radiology

Research Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Biochemistry & Cell Biology

Research Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
General Internal Medicine

Member
Boston University
Whitaker Cardiovascular Institute

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Boston Medical Center

BU Research
NIH RePORTER Research

Synergistic Effects of Medium-chain and Omega-3 Triglycerides on Cellular Omega-3 Fatty Acid Enrichment: Characterization, Mechanisms, and Optimization
01/10/2020 - 12/31/2024 (Subcontract PI)
Trustees Of Columbia University In The City Of New York NIH NIDDK
5R01DK119389-02

Elucidating the effects of statins on pancreatic B-cell metabolism and functions
08/02/2018 - 12/31/2023 (PI)
Kowa Pharmaceuticals America, Inc.

n-3 Diglyceride Emulsions: Characterization of a Novel Neuroprotectant
08/15/2019 - 07/31/2021 (Subcontract PI)
Trustees Of Columbia University In The City Of New York NIH NINDS
1R21NS109717-01A1

Effects of MCT on Enhancing n-3 Fatty Acid Incorporation into Membranes
01/01/2019 - 08/31/2020 (Subcontract PI)
Trustees Of Columbia University In The City Of New York BeijingSciecurePharm

How CD36 and Caveloin-1 Affect Fatty Acid Uptake
01/01/2011 - 12/31/2013 (PI)
American Diabetes Association

NMR and MR Imaging Studies of Plaque Rupture
08/08/2000 - 03/31/2010 (PI)
NIH/National Heart, Lung, and Blood Institute
5 R01 HL61825 04

Investigation of Pepducin Membrane “Flip-Flop” -- Effects of Peptide Sequence and Lipid Composition
01/01/2009 - 12/31/2009 (PI)
Ascent Therapeutics

Transport and Metabolism of Fatty Acids in Adipocytes
04/16/2001 - 03/31/2007 (PI)
NIH/National Heart, Lung, and Blood Institute
5 R01 HL67188 04

NMR Studies of Lipids in Disease
12/08/1997 - 11/30/2000 (PI)
NIH/National Heart, Lung, and Blood Institute
5 R01 HL41904 08

Title

Yr	Title	Project-Sub Proj	Pubs
2010	Imaging the Vascular Consequences of Lipid Deposition	5P50HL083801-05-3	57
2009	Imaging the Vascular Consequences of Lipid Deposition	5P50HL083801-04-3	57
2008	Imaging the Vascular Consequences of Lipid Deposition	5P50HL083801-03-3	57
2007	Imaging the Vascular Consequences of Lipid Deposition	5P50HL083801-02-3	57
2006	Imaging the Vascular Consequences of Lipid Deposition	1P50HL083801-01-3	57
2005	FATTY ACID TRANSPORT--STRUCTURAL AND CELL BIOLOGY	5P01HL026335-25-7	235
2004	FATTY ACID TRANSPORT--STRUCTURAL AND CELL BIOLOGY	5P01HL026335-24-7	235
2004	Transport and Metabolism of Fatty Acids in Adipocytes	5R01HL067188-04	8
2003	Transport and Metabolism of Fatty Acids in Adipocytes	5R01HL067188-03	8
2003	NMR AND MR IMAGING STUDIES OF PLAQUE RUPTURE	5R01HL061825-04	5

Showing 10 of 33 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Taylor EN, Huang N, Lin S, Mortazavi F, Wedeen VJ, Siamwala JH, Gilbert RJ, Hamilton JA. Lipid and smooth muscle architectural pathology in the rabbit atherosclerotic vessel wall using Q-space cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2022 Dec 22; 24(1):74.View Related Profiles.

Taylor, Erik
Mortazavi, Farzad
Hamilton, James
Huang, Nasi

PMID: 36544161; PMCID: PMC9773609; DOI: 10.1186/s12968-022-00897-7;

Jayaraj A, Schwanz HA, Spencer DJ, Bhasin S, Hamilton JA, Jayaram B, Goldman AL, Krishna M, Krishnan M, Shah A, Jin Z, Krenzel E, Nair SN, Ramesh S, Guo W, Wagner G, Arthanari H, Peng L, Lawney B, Jasuja R. Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin. Endocrinology. 2021 02 01; 162(2).View Related Profiles.

Schwanz, Heidi
Hamilton, James

PMID: 33125473; PMCID: PMC7774055; DOI: 10.1210/endocr/bqaa199;

Wang Y, Taylor E, Zikopoulos B, Seta F, Huang N, Hamilton JA, Kantak KM, Morgan KG. Aging-induced microbleeds of the mouse thalamus compared to sensorimotor and memory defects. Neurobiol Aging. 2021 04; 100:39-47.View Related Profiles.

Taylor, Erik
Seta, Francesca
Hamilton, James
Kantak, Kathleen
Morgan, Kathleen

PMID: 33477010; PMCID: PMC8162167; DOI: 10.1016/j.neurobiolaging.2020.11.017;

Taylor EN, Huang N, Wisco J, Wang Y, Morgan KG, Hamilton JA. The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds. J Transl Med. 2020 07 08; 18(1):277.View Related Profiles.

Hamilton, James
Wisco, Jonathan
Morgan, Kathleen

PMID: 32641073; PMCID: PMC7346388; DOI: 10.1186/s12967-020-02441-6;

Jay AG, Simard JR, Huang N, Hamilton JA. SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect FA translocation. J Lipid Res. 2020 05; 61(5):790-807.View Related Profiles.

Jay, Anthony
Hamilton, James
Huang, Nasi

PMID: 32102800; PMCID: PMC7193964; DOI: 10.1194/jlr.RA120000648;

Shao Y, Wichern E, Childress PJ, Adaway M, Misra J, Klunk A, Burr DB, Wek RC, Mosley AL, Liu Y, Robling AG, Brustovetsky N, Hamilton J, Jacobs K, Vashishth D, Stayrook KR, Allen MR, Wallace JM, Bidwell JP. Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality. Am J Physiol Endocrinol Metab. 2019 05 01; 316(5):E749-E772. PMID: 30645175; PMCID: PMC6580174; DOI: 10.1152/ajpendo.00343.2018;

Zeng B, Liao J, Zhang H, Fu S, Chen W, Pan G, Li Q, Chen W, Ferrone S, Wu B, Sun S, Hu J, Ahn MH, Lin Z, Yu D, Ou Z, Wang X, Mo F, Huang N, Hamilton JA, Li J, Fan S. Novel ANO5 mutation c.1067G>T (p.C356F) identified by whole genome sequencing in a big family with atypical gnathodiaphyseal dysplasia. Head Neck. 2019 01; 41(1):230-238. PMID: 30554457; PMCID: PMC8779835; DOI: 10.1002/hed.25516;

Mitra R, Qiao J, Madhavan S, O'Neil GL, Ritchie B, Kulkarni P, Sridhar S, van de Ven AL, Kemmerling EMC, Ferris C, Hamilton JA, Ebong EE. The comparative effects of high fat diet or disturbed blood flow on glycocalyx integrity and vascular inflammation. Transl Med Commun. 2018; 3. PMID: 30957020; PMCID: PMC6447085; DOI: 10.1186/s41231-018-0029-9;

Ronodeep Mitra, Ju Qiao, Sudharsan Madhavan, Gerard L. O’Neil, Bailey Ritchie, Praveen Kulkarni, Srinivas Sridhar, Anne L. van de Ven, Erica M. Cherry Kemmerling, Craig Ferris, James A. Hamilton and Eno E. Ebong. The comparative effects of high fat diet or disturbed blood flow on glycocalyx integrity and vascular inflammation. Translational Medicine Communications. 2018; 10(3).

Taylor E, Huang N, Bodde J, Ellison A, Killiany R, Bachschmid MM, Hamilton J. MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits. J Transl Med. 2018 08 01; 16(1):215.View Related Profiles.

Taylor, Erik
Hamilton, James
Bachschmid, Markus
Huang, Nasi
Killiany, Ronald

PMID: 30068362; PMCID: PMC6071403; DOI: 10.1186/s12967-018-1587-3;

Showing 10 of 225 results. Show More

EA Kolar, E Gajrawala, J Deeney, J Hamilton. FASEB JOURNAL. Understanding the role of pancreatic beta-cell CD36 in the development of Type 2 Diabetes . 2018; 32(1).
TE Van Dyke, H Hasturk, A Kantarci, JA Hamilton. Methods for Stabilizing Atherosclerotic Plaques Using Lipoxins, Resolvins, and Analogs Thereof. 2018.

Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV, Kondo A, Zhou XZ, Miry O, Vose LR, Gopaul KR, Upreti C, Nowinski CJ, Cantu RC, Alvarez VE, Hildebrandt AM, Franz ES, Konrad J, Hamilton JA, Hua N, Tripodis Y, Anderson AT, Howell GR, Kaufer D, Hall GF, Lu KP, Ransohoff RM, Cleveland RO, Kowall NW, Stein TD, Lamb BT, Huber BR, Moss WC, Friedman A, Stanton PK, McKee AC, Goldstein LE. Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model. Brain. 2018 02 01; 141(2):422-458.View Related Profiles.

McKee, Ann
Huber, Bertrand
Nowinski, Christopher
Hamilton, James
Moncaster, Juliet
Goldstein, Lee
Wojnarowicz, Mark
Kowall, Neil
Hua, Ning
Casey, Noel
Minaeva, Olga
Cantu, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 29360998; PMCID: PMC5837414; DOI: 10.1093/brain/awx350;

Hamilton JA, Hasturk H, Kantarci A, Serhan CN, Van Dyke T. Atherosclerosis, Periodontal Disease, and Treatment with Resolvins. Curr Atheroscler Rep. 2017 Nov 06; 19(12):57.View Related Profiles.

Hamilton, James
Van Dyke, Thomas

PMID: 29110146

Hamilton J, Hasturk H, Kantarci A, Van Dyke T, Phinikaridou A. Atherothrombosis: Resolution of vessel wall inflammation and limitation of thrombosis and thrombus propagation by resolvins. Atherosclerosis. 2017 Aug; 263:e144-e145.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James
Van Dyke, Thomas

PMID: 29365572

J Hamilton, H Hasturk, A Kantarci, T Van Dyke, A Phinikaridou. Atherosclerosis. Atherothrombosis: Resolution of vessel wall inflammation and limitation of thrombosis and thrombus propagation by resolvins . 2017; 263:e144-e145.

Hua N, Takahashi H, Yee GM, Kitajima Y, Katagiri S, Kojima M, Anzai K, Eguchi Y, Hamilton JA. Influence of muscle fiber type composition on early fat accumulation under high-fat diet challenge. PLoS One. 2017; 12(8):e0182430.View Related Profiles.

Hamilton, James
Hua, Ning

PMID: 28763507; PMCID: PMC5538743; DOI: 10.1371/journal.pone.0182430;

Stein-Merlob AF, Hara T, McCarthy JR, Mauskapf A, Hamilton JA, Ntziachristos V, Libby P, Jaffer FA. Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging. Circ Cardiovasc Imaging. 2017 May; 10(5). PMID: 28487316; PMCID: PMC5509162; DOI: 10.1161/CIRCIMAGING.116.005813;

D Lima A, Hua N, C Maranhão R, A Hamilton J. Evaluation of atherosclerotic lesions in cholesterol-fed mice during treatment with paclitaxel in lipid nanoparticles: a magnetic resonance imaging study. J Biomed Res. 2017 Jan 19; 31(2):116-121.View Related Profiles.

Hamilton, James
Hua, Ning

PMID: 28808193; PMCID: PMC5445214; DOI: 10.7555/JBR.31.20160123;

Jay AG, Hamilton JA. Disorder Amidst Membrane Order: Standardizing Laurdan Generalized Polarization and Membrane Fluidity Terms. J Fluoresc. 2017 Jan; 27(1):243-249.View Related Profiles.

Jay, Anthony
Hamilton, James

PMID: 27738919; DOI: 10.1007/s10895-016-1951-8;

Jay AG, Hamilton JA. The enigmatic membrane fatty acid transporter CD36: New insights into fatty acid binding and their effects on uptake of oxidized LDL. Prostaglandins Leukot Essent Fatty Acids. 2018 11; 138:64-70.View Related Profiles.

Jay, Anthony
Hamilton, James

PMID: 27288302; DOI: 10.1016/j.plefa.2016.05.005;

A Buckler, A Madabhushi, J Hamilton, S Agner, M Rosen. Classification of biological tissue by multi-mode data registration, segmentation and characterization. 2016.

Pham TA, Hua N, Phinikaridou A, Killiany R, Hamilton J. Early in vivo discrimination of vulnerable atherosclerotic plaques that disrupt: A serial MRI study. Atherosclerosis. 2016 Jan; 244:101-7.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James
Hua, Ning
Killiany, Ronald

PMID: 26606442; DOI: 10.1016/j.atherosclerosis.2015.11.013;

Hua N, Baik F, Pham T, Phinikaridou A, Giordano N, Friedman B, Whitney M, Nguyen QT, Tsien RY, Hamilton JA. Identification of High-Risk Plaques by MRI and Fluorescence Imaging in a Rabbit Model of Atherothrombosis. PLoS One. 2015; 10(10):e0139833.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James
Hua, Ning

PMID: 26448434; PMCID: PMC4598148; DOI: 10.1371/journal.pone.0139833;

Heidi A Schwanz, Ning Hua, Connie L Slocum, Carolyn D Kramer, Michael Whitney, Tao Jiang, Caroline A Genco, Roger Y Tsien, James A Hamilton. Arteriosclerosis, Thrombosis, and Vascular Biology. Targeted Activatable Cell-Penetrating Peptides Identify Atherosclerotic Plaques in Mice with Noninvasive Magnetic Resonance Imaging. 2015; 34(Suppl 1):A272-A272.
J Hamilton, P Miguel, A Jay. The FASEB Journal. Fatty acid binding to CD36 affects oxLDL uptake. 2015; 29(1):566.8.

Hasturk H, Abdallah R, Kantarci A, Nguyen D, Giordano N, Hamilton J, Van Dyke TE. Resolvin E1 (RvE1) Attenuates Atherosclerotic Plaque Formation in Diet and Inflammation-Induced Atherogenesis. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1123-33.View Related Profiles.

Hamilton, James
Van Dyke, Thomas

PMID: 25792445; PMCID: PMC4415167; DOI: 10.1161/ATVBAHA.115.305324;

Jay AG, Chen AN, Paz MA, Hung JP, Hamilton JA. CD36 binds oxidized low density lipoprotein (LDL) in a mechanism dependent upon fatty acid binding. J Biol Chem. 2015 Feb 20; 290(8):4590-603.View Related Profiles.

Jay, Anthony
Hamilton, James
Paz, Miguel

PMID: 25555908; PMCID: PMC4335201; DOI: 10.1074/jbc.M114.627026;

Papadopoulos G, Kramer CD, Slocum CS, Weinberg EO, Hua N, Gudino CV, Hamilton JA, Genco CA. A mouse model for pathogen-induced chronic inflammation at local and systemic sites. J Vis Exp. 2014; (90):e51556.View Related Profiles.

Genco, Caroline
Kramer, Carolyn
Slocum, Connie
Weinberg, Ellen
Papadopoulos, George
Hamilton, James
Hua, Ning

PMID: 25146644; PMCID: PMC4758716; DOI: 10.3791/51556;

Slocum C, Coats SR, Hua N, Kramer C, Papadopoulos G, Weinberg EO, Gudino CV, Hamilton JA, Darveau RP, Genco CA. Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation. PLoS Pathog. 2014 Jul; 10(7):e1004215.View Related Profiles.

Genco, Caroline
Kramer, Carolyn
Slocum, Connie
Weinberg, Ellen
Papadopoulos, George
Hamilton, James
Hua, Ning

PMID: 25010102; PMCID: PMC4092147; DOI: 10.1371/journal.ppat.1004215;

Hua N, Chen Z, Phinikaridou A, Pham T, Qiao Y, LaValley MP, Bigornia SJ, Ruth MR, Apovian CM, Ruberg FL, Hamilton JA. The influence of pericardial fat upon left ventricular function in obese females: evidence of a site-specific effect. J Cardiovasc Magn Reson. 2014; 16:37.View Related Profiles.

Phinikaridou, Alkystis
Apovian, Caroline
Ruberg, Frederick
Hamilton, James
Ruth, Megan
LaValley, Michael
Hua, Ning

PMID: 24884541; PMCID: PMC4046092; DOI: 10.1186/1532-429X-16-37;

Park YC, Smith JB, Pham T, Whitaker RD, Sucato CA, Hamilton JA, Bartolak-Suki E, Wong JY. Effect of PEG molecular weight on stability, T2 contrast, cytotoxicity, and cellular uptake of superparamagnetic iron oxide nanoparticles (SPIONs). Colloids Surf B Biointerfaces. 2014 Jul 1; 119:106-14.View Related Profiles.

Bartolak-Suki, Erzsebet
Hamilton, James
Wong, Joyce

PMID: 24877593; PMCID: PMC4108172; DOI: 10.1016/j.colsurfb.2014.04.027;

Wong S, Kirkland JL, Schwanz HA, Simmons AL, Hamilton JA, Corkey BE, Guo W. Effects of thiol antioxidant ß-mercaptoethanol on diet-induced obese mice. Life Sci. 2014 Jun 27; 107(1-2):32-41.View Related Profiles.

Simmons, Amber
Corkey, Barbara
Schwanz, Heidi
Hamilton, James

PMID: 24802126; PMCID: PMC4327985; DOI: 10.1016/j.lfs.2014.04.031;

Wan T, Madabhushi A, Phinikaridou A, Hamilton JA, Hua N, Pham T, Danagoulian J, Kleiman R, Buckler AJ. Spatio-temporal texture (SpTeT) for distinguishing vulnerable from stable atherosclerotic plaque on dynamic contrast enhancement (DCE) MRI in a rabbit model. Med Phys. 2014 Apr; 41(4):042303.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James
Hua, Ning

PMID: 24694153; PMCID: PMC3987744; DOI: 10.1118/1.4867861;

Xu S, Jay A, Brunaldi K, Huang N, Hamilton JA. CD36 enhances fatty acid uptake by increasing the rate of intracellular esterification but not transport across the plasma membrane. Biochemistry. 2013 Oct 15; 52(41):7254-61.View Related Profiles.

Jay, Anthony
Hamilton, James
Huang, Nasi

PMID: 24090054; DOI: 10.1021/bi400914c;

Park DW, Kruger GH, Rubin JM, Hamilton J, Gottschalk P, Dodde RE, Shih AJ, Weitzel WF. Quantification of ultrasound correlation-based flow velocity mapping and edge velocity gradient measurement. J Ultrasound Med. 2013 Oct; 32(10):1815-30. PMID: 24065263; DOI: 10.7863/ultra.32.10.1815;

Denis GV, Hamilton JA. Healthy obese persons: how can they be identified and do metabolic profiles stratify risk? Curr Opin Endocrinol Diabetes Obes. 2013 Oct; 20(5):369-76.View Related Profiles.

Denis, Gerald
Hamilton, James

PMID: 23974763; PMCID: PMC3934493; DOI: 10.1097/01.med.0000433058.78485.b3;

Hamilton JA. NMR reveals molecular interactions and dynamics of fatty acid binding to albumin. Biochim Biophys Acta. 2013 Dec; 1830(12):5418-26. PMID: 23939311

A Jay, A Chen, JA Hamilton. The FASEB Journal. Searching the extracellular domain of CD36 for fatty acid binding by Surface Plasmon Resonance . 2013; 27(1supplemen):1019.3-1019.3.
AJ Buckler, JA Hamilton, A Madabhushi, JC Keith. Non-invasive theranostic to predict and assess response to atherosclerotic drugs. 2013.
ES Krenzel, Z Chen, JA Hamilton. Biochemistry. Correspondence of fatty acid and drug binding sites on human serum albumin: a two-dimensional nuclear magnetic resonance study. 2013; 52(9):1559-1567.

Krenzel ES, Chen Z, Hamilton JA. Correspondence of fatty acid and drug binding sites on human serum albumin: a two-dimensional nuclear magnetic resonance study. Biochemistry. 2013 Mar 5; 52(9):1559-67.View Related Profiles.

Hamilton, James
Chen, Zhongjing

PMID: 23360066; DOI: 10.1021/bi301458b;

Phinikaridou A, Hua N, Pham T, Hamilton JA. Regions of low endothelial shear stress colocalize with positive vascular remodeling and atherosclerotic plaque disruption: an in vivo magnetic resonance imaging study. Circ Cardiovasc Imaging. 2013 Mar 1; 6(2):302-10.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James
Hua, Ning

PMID: 23357244; DOI: 10.1161/CIRCIMAGING.112.000176;

Hayashi C, Papadopoulos G, Gudino CV, Weinberg EO, Barth KR, Madrigal AG, Chen Y, Ning H, LaValley M, Gibson FC, Hamilton JA, Genco CA. Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen. J Immunol. 2012 Oct 1; 189(7):3681-8.View Related Profiles.

Madrigal, Andres
Genco, Caroline
Hayashi, Chie
Weinberg, Ellen
Gibson, Frank
Papadopoulos, George
Hamilton, James
Barth, Kenneth
LaValley, Michael

PMID: 22956579; PMCID: PMC3448820; DOI: 10.4049/jimmunol.1201541;

Phinikaridou A, Qiao Y, Giordano N, Hamilton JA. Detection of thrombus size and protein content by ex vivo magnetization transfer and diffusion weighted MRI. J Cardiovasc Magn Reson. 2012; 14:45.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James

PMID: 22731842; PMCID: PMC3419091; DOI: 10.1186/1532-429X-14-45;

Cai J, Lücke C, Chen Z, Qiao Y, Klimtchuk E, Hamilton JA. Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited. Biophys J. 2012 Jun 6; 102(11):2585-94.View Related Profiles.

Klimtchuk, Elena
Hamilton, James
Chen, Zhongjing

PMID: 22713574; PMCID: PMC3368126; DOI: 10.1016/j.bpj.2012.04.039;

TA Pham, N Hua, A Phinikaridou, N Giordano, JA Hamilton. Arteriosclerosis. Serial MRI Differentiates the Natural History of Stable and Vulnerable Plaques in a Rabbit Aorta. 2012; 32(Suppl 1):A348-A348.

Qiao Y, Hallock KJ, Hamilton JA. Magnetization transfer magnetic resonance of human atherosclerotic plaques ex vivo detects areas of high protein density. J Cardiovasc Magn Reson. 2011; 13:73.View Related Profiles.

Hamilton, James
Hallock, Kevin

PMID: 22107813; PMCID: PMC3278375; DOI: 10.1186/1532-429X-13-73;

Anderson SW, Jara H, Ozonoff A, O'Brien M, Hamilton JA, Soto JA. Effect of disease progression on liver apparent diffusion coefficient and T2 values in a murine model of hepatic fibrosis at 11.7 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):140-6.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Hamilton, James
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 21990020; DOI: 10.1002/jmri.22807;

Souza SL, Hallock KJ, Funari SS, Vaz WL, Hamilton JA, Melo E. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chem Phys Lipids. 2011 Oct; 164(7):664-71.View Related Profiles.

Hamilton, James
Hallock, Kevin

PMID: 21756886; DOI: 10.1016/j.chemphyslip.2011.06.011;

Phinikaridou A, Hamilton JA. Application of MRI to detect high-risk atherosclerotic plaque. Expert Rev Cardiovasc Ther. 2011 May; 9(5):545-50.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James

PMID: 21615314; DOI: 10.1586/erc.11.31;

Anderson SW, Soto JA, Milch HN, Ozonoff A, O'Brien M, Hamilton JA, Jara HJ. Effect of disease progression on liver apparent diffusion coefficient values in a murine model of NASH at 11.7 Tesla MRI. J Magn Reson Imaging. 2011 Apr; 33(4):882-8.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Hamilton, James
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 21448953; DOI: 10.1002/jmri.22481;

Hayashi C, Viereck J, Hua N, Phinikaridou A, Madrigal AG, Gibson FC, Hamilton JA, Genco CA. Porphyromonas gingivalis accelerates inflammatory atherosclerosis in the innominate artery of ApoE deficient mice. Atherosclerosis. 2011 Mar; 215(1):52-9.View Related Profiles.

Phinikaridou, Alkystis
Madrigal, Andres
Genco, Caroline
Hayashi, Chie
Gibson, Frank
Hamilton, James
Hua, Ning

PMID: 21251656; PMCID: PMC3057233; DOI: 10.1016/j.atherosclerosis.2010.12.009;

Liu Y, Atkinson D. Enhancing the contrast of ApoB to locate the surface components in the 3D density map of human LDL. J Mol Biol. 2011 Jan 7; 405(1):274-83.View Related Profiles.

Atkinson, David
Hamilton, James

PMID: 21029740; PMCID: PMC3006490; DOI: 10.1016/j.jmb.2010.10.034;

Simard JR, Meshulam T, Pillai BK, Kirber MT, Brunaldi K, Xu S, Pilch PF, Hamilton JA. Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity. J Lipid Res. 2010 May; 51(5):914-22.View Related Profiles.

Hamilton, James
Kirber, Michael
Pilch, Paul
Meshulam, Tova

PMID: 20388923; PMCID: PMC2853459; DOI: 10.1194/jlr.M900251;

Phinikaridou A, Ruberg FL, Hallock KJ, Qiao Y, Hua N, Viereck J, Hamilton JA. In vivo detection of vulnerable atherosclerotic plaque by MRI in a rabbit model. Circ Cardiovasc Imaging. 2010 May; 3(3):323-32.View Related Profiles.

Phinikaridou, Alkystis
Ruberg, Frederick
Hamilton, James
Hallock, Kevin
Hua, Ning

PMID: 20194634; DOI: 10.1161/CIRCIMAGING.109.918524;

Guo Y, Tan LJ, Lei SF, Yang TL, Chen XD, Zhang F, Chen Y, Pan F, Yan H, Liu X, Tian Q, Zhang ZX, Zhou Q, Qiu C, Dong SS, Xu XH, Guo YF, Zhu XZ, Liu SL, Wang XL, Li X, Luo Y, Zhang LS, Li M, Wang JT, Wen T, Drees B, Hamilton J, Papasian CJ, Recker RR, Song XP, Cheng J, Deng HW. Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet. 2010 Jan; 6(1):e1000806. PMID: 20072603; PMCID: PMC2794362; DOI: 10.1371/journal.pgen.1000806;

Brunaldi K, Huang N, Hamilton JA. Fatty acids are rapidly delivered to and extracted from membranes by methyl-beta-cyclodextrin. J Lipid Res. 2010 Jan; 51(1):120-31.View Related Profiles.

Hamilton, James
Huang, Nasi

PMID: 19625735; PMCID: PMC2789772; DOI: 10.1194/M900200-JLR200;

Miller J, Agarwal A, Devi LA, Fontanini K, Hamilton JA, Pin JP, Shields DC, Spek CA, Sakmar TP, Kuliopulos A, Hunt SW. Insider access: pepducin symposium explores a new approach to GPCR modulation. Ann N Y Acad Sci. 2009 Nov; 1180 Suppl 1:E1-12. PMID: 19925639; DOI: 10.1111/j.1749-6632.2009.05326.x;

Ruberg FL, Chen Z, Hua N, Bigornia S, Guo Z, Hallock K, Jara H, LaValley M, Phinikaridou A, Qiao Y, Viereck J, Apovian CM, Hamilton JA. The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome. Obesity (Silver Spring). 2010 Jun; 18(6):1116-21.View Related Profiles.

Phinikaridou, Alkystis
Apovian, Caroline
Ruberg, Frederick
Jara, Hernan
Hamilton, James
Hallock, Kevin
LaValley, Michael
Hua, Ning
Chen, Zhongjing

PMID: 19875992; PMCID: PMC3264050; DOI: 10.1038/oby.2009.363;

Pillai BK, Jasuja R, Simard JR, Hamilton JA. Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy. J Biol Chem. 2009 Nov 27; 284(48):33296-304.View Related Profiles.

Hamilton, James
Jasuja, Ravi

PMID: 19801636; PMCID: PMC2785172; DOI: 10.1074/jbc.M109.043737;

Getty-Kaushik L, Viereck JC, Goodman JM, Guo Z, LeBrasseur NK, Richard AM, Flanagan JN, Yaney GC, Hamilton JA, Tornheim K. Mice deficient in phosphofructokinase-M have greatly decreased fat stores. Obesity (Silver Spring). 2010 Mar; 18(3):434-40.View Related Profiles.

Hamilton, James
Tornheim, Keith

PMID: 19779479; PMCID: PMC2871150; DOI: 10.1038/oby.2009.295;

Guo W, Wong S, Pudney J, Jasuja R, Hua N, Jiang L, Miller A, Hruz PW, Hamilton JA, Bhasin S. Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir. Arterioscler Thromb Vasc Biol. 2009 Dec; 29(12):2028-32.View Related Profiles.

Hamilton, James
Pudney, Jeffrey
Hua, Ning
Bhasin, Shalender
Guo, Wen

PMID: 19762785; PMCID: PMC2783673; DOI: 10.1161/ATVBAHA.109.191304;

Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, Guo W. Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice. Diabetes. 2009 Aug; 58(8):1739-48.View Related Profiles.

Hamilton, James
Hua, Ning
Bhasin, Shalender
Guo, Wen

PMID: 19509018; PMCID: PMC2712781; DOI: 10.2337/db09-0349;

Decano JL, Viereck JC, McKee AC, Hamilton JA, Ruiz-Opazo N, Herrera VL. Early-life sodium exposure unmasks susceptibility to stroke in hyperlipidemic, hypertensive heterozygous Tg25 rats transgenic for human cholesteryl ester transfer protein. Circulation. 2009 Mar 24; 119(11):1501-9.View Related Profiles.

McKee, Ann
Hamilton, James
Decano, Julius
Ruiz-Opazo, Nelson
Herrera, Victoria

PMID: 19273719; PMCID: PMC2825876; DOI: 10.1161/CIRCULATIONAHA.108.833327;

Phinikaridou A, Hallock KJ, Qiao Y, Hamilton JA. A robust rabbit model of human atherosclerosis and atherothrombosis. J Lipid Res. 2009 May; 50(5):787-97.View Related Profiles.

Phinikaridou, Alkystis
Hamilton, James
Hallock, Kevin

PMID: 19141434; PMCID: PMC2666165; DOI: 10.1194/jlr.M800460-JLR200;

Lacey DC, Simmons PJ, Graves SE, Hamilton JA. Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation. Osteoarthritis Cartilage. 2009 Jun; 17(6):735-42. PMID: 19136283; DOI: 10.1016/j.joca.2008.11.011;

Qiao Y, Farber A, Semaan E, Hamilton JA. Images in cardiovascular medicine. Healing of an asymptomatic carotid plaque ulceration. Circulation. 2008 Sep 2; 118(10):e147-8.View Related Profiles.

Farber, Alik
Hamilton, James

PMID: 18765382; PMCID: PMC2703661; DOI: 10.1161/CIRCULATIONAHA.108.764779;

Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, Choong K, Tchkonia T, Lebrasseur NK, Flanagan JN, Hamilton JA, Viereck JC, Narula NS, Kirkland JL, Jasuja R. Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Mol Cell Endocrinol. 2008 Dec 16; 296(1-2):32-40.View Related Profiles.

Hamilton, James
Bhasin, Shalender
Guo, Wen

PMID: 18801408; PMCID: PMC2873614; DOI: 10.1016/j.mce.2008.08.019;

Simard JR, Pillai BK, Hamilton JA. Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase. Biochemistry. 2008 Sep 2; 47(35):9081-9. PMID: 18693753; DOI: 10.1021/bi800697q;

Simard JR, Kamp F, Hamilton JA. Measuring the adsorption of Fatty acids to phospholipid vesicles by multiple fluorescence probes. Biophys J. 2008 Jun; 94(11):4493-503. PMID: 18296488; PMCID: PMC2480657; DOI: 10.1529/biophysj.107.121186;

Izumiya Y, Hopkins T, Morris C, Sato K, Zeng L, Viereck J, Hamilton JA, Ouchi N, LeBrasseur NK, Walsh K. Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice. Cell Metab. 2008 Feb; 7(2):159-72.View Related Profiles.

Hamilton, James
Walsh, Kenneth
Zeng, Ling

PMID: 18249175; PMCID: PMC2828690; DOI: 10.1016/j.cmet.2007.11.003;

Zhao LJ, Jiang H, Papasian CJ, Maulik D, Drees B, Hamilton J, Deng HW. Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis. J Bone Miner Res. 2008 Jan; 23(1):17-29. PMID: 17784844; PMCID: PMC2663586; DOI: 10.1359/JBMR.070813;

Hamilton JA. New insights into the roles of proteins and lipids in membrane transport of fatty acids. Prostaglandins Leukot Essent Fatty Acids. 2007 Nov-Dec; 77(5-6):355-61. PMID: 18032007

Watkins PA, Hamilton JA. Roundtable discussion of session 2: lipoproteins and polyunsaturated fatty acids. J Mol Neurosci. 2007 Sep; 33(1):74-9. PMID: 17901549

Watkins PA, Hamilton JA. Roundtable discussion of session 1: mechanisms of lipid uptake and transport in the brain. J Mol Neurosci. 2007 Sep; 33(1):45-50. PMID: 17901545

Hamilton JA, Brunaldi K. A model for fatty acid transport into the brain. J Mol Neurosci. 2007 Sep; 33(1):12-7. PMID: 17901540

Hamilton JA, Hillard CJ, Spector AA, Watkins PA. Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders. J Mol Neurosci. 2007 Sep; 33(1):2-11. PMID: 17901539

Watkins PA, Hamilton JA. Roundtable discussion of session 3: eicosanoids in brain function. J Mol Neurosci. 2007 Sep; 33(1):100-4. PMID: 17901553

Watkins PA, Hamilton JA. Roundtable discussion of session 4: fatty acids and lipids in brain disorders. J Mol Neurosci. 2007 Sep; 33(1):120-4. PMID: 17901556

Katz R, Hamilton JA, Pownall HJ, Deckelbaum RJ, Hillard CJ, Leboeuf RC, Watkins PA. Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research. J Mol Neurosci. 2007 Sep; 33(1):146-50. PMID: 17901559

Duncanson WJ, Figa MA, Hallock K, Zalipsky S, Hamilton JA, Wong JY. Targeted binding of PLA microparticles with lipid-PEG-tethered ligands. Biomaterials. 2007 Nov; 28(33):4991-9.View Related Profiles.

Hamilton, James
Wong, Joyce
Hallock, Kevin
Duncanson, Wynter

PMID: 17707503; PMCID: PMC2679848; DOI: 10.1016/j.biomaterials.2007.05.044;

Ziouzenkova O, Orasanu G, Sharlach M, Akiyama TE, Berger JP, Viereck J, Hamilton JA, Tang G, Dolnikowski GG, Vogel S, Duester G, Plutzky J. Retinaldehyde represses adipogenesis and diet-induced obesity. Nat Med. 2007 Jun; 13(6):695-702. PMID: 17529981; PMCID: PMC2233696; DOI: 10.1038/nm1587;

Qiao Y, Ronen I, Viereck J, Ruberg FL, Hamilton JA. Identification of atherosclerotic lipid deposits by diffusion-weighted imaging. Arterioscler Thromb Vasc Biol. 2007 Jun; 27(6):1440-6.View Related Profiles.

Ruberg, Frederick
Hamilton, James

PMID: 17379838; PMCID: PMC2910580; DOI: 10.1161/ATVBAHA.107.141028;

Zhao LJ, Liu YJ, Liu PY, Hamilton J, Recker RR, Deng HW. Relationship of obesity with osteoporosis. J Clin Endocrinol Metab. 2007 May; 92(5):1640-6. PMID: 17299077; PMCID: PMC1868430; DOI: 10.1210/jc.2006-0572;

Hamilton JA, Deckelbaum RJ. Crystal structure of CETP: new hopes for raising HDL to decrease risk of cardiovascular disease? Nat Struct Mol Biol. 2007 Feb; 14(2):95-7. PMID: 17277799

Simard JR, Kamp F, Hamilton JA. Acrylodan-labeled intestinal fatty acid-binding protein to measure concentrations of unbound fatty acids. Methods Mol Biol. 2007; 400:27-43. PMID: 17951725

Brunaldi K, Simard JR, Kamp F, Rewal C, Asawakarn T, O'Shea P, Hamilton JA. Fluorescence assays for measuring fatty acid binding and transport through membranes. Methods Mol Biol. 2007; 400:237-55. PMID: 17951738

Hallock KJ, Hamilton JA. Ex vivo identification of atherosclerotic plaque calcification by a 31P solid-state magnetic resonance imaging technique. Magn Reson Med. 2006 Dec; 56(6):1380-3.View Related Profiles.

Hamilton, James
Hallock, Kevin

PMID: 17089379

Kamp F, Hamilton JA. How fatty acids of different chain length enter and leave cells by free diffusion. Prostaglandins Leukot Essent Fatty Acids. 2006 Sep; 75(3):149-59. PMID: 16829065

Simard JR, Zunszain PA, Hamilton JA, Curry S. Location of high and low affinity fatty acid binding sites on human serum albumin revealed by NMR drug-competition analysis. J Mol Biol. 2006 Aug 11; 361(2):336-51. PMID: 16844140

Lücke C, Qiao Y, van Moerkerk HT, Veerkamp JH, Hamilton JA. Fatty-acid-binding protein from the flight muscle of Locusta migratoria: evolutionary variations in fatty acid binding. Biochemistry. 2006 May 23; 45(20):6296-305. PMID: 16700541

Lücke C, Gantz DL, Klimtchuk E, Hamilton JA. Interactions between fatty acids and alpha-synuclein. J Lipid Res. 2006 Aug; 47(8):1714-24.View Related Profiles.

Klimtchuk, Elena
Hamilton, James

PMID: 16687662

Meshulam T, Simard JR, Wharton J, Hamilton JA, Pilch PF. Role of caveolin-1 and cholesterol in transmembrane fatty acid movement. Biochemistry. 2006 Mar 7; 45(9):2882-93.View Related Profiles.

Hamilton, James
Pilch, Paul
Meshulam, Tova

PMID: 16503643

Xie W, Hamilton JA, Kirkland JL, Corkey BE, Guo W. Oleate-induced formation of fat cells with impaired insulin sensitivity. Lipids. 2006 Mar; 41(3):267-71.View Related Profiles.

Corkey, Barbara
Hamilton, James
Guo, Wen

PMID: 16711601

Simard JR, Zunszain PA, Ha CE, Yang JS, Bhagavan NV, Petitpas I, Curry S, Hamilton JA. Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):17958-63. PMID: 16330771; PMCID: PMC1312385; DOI: 10.1073/pnas.0506440102;

Ruberg FL, Viereck J, Phinikaridou A, Qiao Y, Loscalzo J, Hamilton JA. Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS. J Lipid Res. 2006 Feb; 47(2):310-7.View Related Profiles.

Phinikaridou, Alkystis
Ruberg, Frederick
Hamilton, James

PMID: 16317172

Guo W, Huang N, Cai J, Xie W, Hamilton JA. Fatty acid transport and metabolism in HepG2 cells. Am J Physiol Gastrointest Liver Physiol. 2006 Mar; 290(3):G528-34.View Related Profiles.

Hamilton, James
Huang, Nasi
Guo, Wen

PMID: 16254047

Guo W, Xie W, Lei T, Hamilton JA. Eicosapentaenoic acid, but not oleic acid, stimulates beta-oxidation in adipocytes. Lipids. 2005 Aug; 40(8):815-21.View Related Profiles.

Hamilton, James
Guo, Wen

PMID: 16296400

Skinner NA, MacIsaac CM, Hamilton JA, Visvanathan K. Regulation of Toll-like receptor (TLR)2 and TLR4 on CD14dimCD16+ monocytes in response to sepsis-related antigens. Clin Exp Immunol. 2005 Aug; 141(2):270-8. PMID: 15996191; PMCID: PMC1809439; DOI: 10.1111/j.1365-2249.2005.02839.x;

Viereck J, Ruberg FL, Qiao Y, Perez AS, Detwiller K, Johnstone M, Hamilton JA. MRI of atherothrombosis associated with plaque rupture. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):240-5.View Related Profiles.

Ruberg, Frederick
Hamilton, James

PMID: 15528478

Johnstone MT, Perez AS, Nasser I, Stewart R, Vaidya A, Al Ammary F, Schmidt B, Horowitz G, Dolgoff J, Hamilton J, Quist WC. Angiotensin receptor blockade with candesartan attenuates atherosclerosis, plaque disruption, and macrophage accumulation within the plaque in a rabbit model. Circulation. 2004 Oct 5; 110(14):2060-5. PMID: 15451796; PMCID: PMC2906248

Hamilton JA. Fatty acid interactions with proteins: what X-ray crystal and NMR solution structures tell us. Prog Lipid Res. 2004 May; 43(3):177-99. PMID: 15003394

Botnar RM, Perez AS, Witte S, Wiethoff AJ, Laredo J, Hamilton J, Quist W, Parsons EC, Vaidya A, Kolodziej A, Barrett JA, Graham PB, Weisskoff RM, Manning WJ, Johnstone MT. In vivo molecular imaging of acute and subacute thrombosis using a fibrin-binding magnetic resonance imaging contrast agent. Circulation. 2004 Apr 27; 109(16):2023-9. PMID: 15066940; PMCID: PMC2910574

Lei T, Xie W, Han J, Corkey BE, Hamilton JA, Guo W. Medium-chain Fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation. Obes Res. 2004 Apr; 12(4):599-611.View Related Profiles.

Corkey, Barbara
Hamilton, James
Guo, Wen

PMID: 15090627

Kamp F, Kizilbash N, Corkey BE, Berggren PO, Hamilton JA. Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism. Diabetes. 2003 Oct; 52(10):2526-31.View Related Profiles.

Corkey, Barbara
Hamilton, James

PMID: 14514636

Pownall HJ, Hamilton JA. Energy translocation across cell membranes and membrane models. Acta Physiol Scand. 2003 Aug; 178(4):357-65. PMID: 12864740

Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA. Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism. Biochemistry. 2003 Jun 24; 42(24):7339-47. PMID: 12809489

Hamilton JA. Fast flip-flop of cholesterol and fatty acids in membranes: implications for membrane transport proteins. Curr Opin Lipidol. 2003 Jun; 14(3):263-71. PMID: 12840657

Han J, Hamilton JA, Kirkland JL, Corkey BE, Guo W. Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats. Obes Res. 2003 Jun; 11(6):734-44.View Related Profiles.

Corkey, Barbara
Hamilton, James
Guo, Wen

PMID: 12805394

Lücke C, Kizilbash N, van Moerkerk HT, Veerkamp JH, Hamilton JA. NMR assignment and structural characterization of the fatty acid binding protein from the flight muscle of Locusta migratoria. J Biomol NMR. 2003 Apr; 25(4):355-6. PMID: 12766397

Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron. 2003 Feb 20; 37(4):583-95. PMID: 12597857

Johnson RA, Hamilton JA, Worgall TS, Deckelbaum RJ. Free fatty acids modulate intermembrane trafficking of cholesterol by increasing lipid mobilities: novel 13C NMR analyses of free cholesterol partitioning. Biochemistry. 2003 Feb 18; 42(6):1637-45. PMID: 12578377

Kamp F, Guo W, Souto R, Pilch PF, Corkey BE, Hamilton JA. Rapid flip-flop of oleic acid across the plasma membrane of adipocytes. J Biol Chem. 2003 Mar 7; 278(10):7988-95.View Related Profiles.

Corkey, Barbara
Hamilton, James
Pilch, Paul
Guo, Wen

PMID: 12499383

Hamilton JA, Guo W, Kamp F. Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins? Mol Cell Biochem. 2002 Oct; 239(1-2):17-23.View Related Profiles.

Hamilton, James
Guo, Wen

PMID: 12479564

Ho JK, Duclos RI, Hamilton JA. Interactions of acyl carnitines with model membranes: a (13)C-NMR study. J Lipid Res. 2002 Sep; 43(9):1429-39. PMID: 12235174

Guo W, Kurze V, Huber T, Afdhal NH, Beyer K, Hamilton JA. A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems. Biophys J. 2002 Sep; 83(3):1465-78.View Related Profiles.

Hamilton, James
Guo, Wen

PMID: 12202372; PMCID: PMC1302245

Hamilton JA. How fatty acids bind to proteins: the inside story from protein structures. Prostaglandins Leukot Essent Fatty Acids. 2002 Aug-Sep; 67(2-3):65-72. PMID: 12324222

Choi JK, Ho J, Curry S, Qin D, Bittman R, Hamilton JA. Interactions of very long-chain saturated fatty acids with serum albumin. J Lipid Res. 2002 Jul; 43(7):1000-10. PMID: 12091483

Johnstone MT, Botnar RM, Perez AS, Stewart R, Quist WC, Hamilton JA, Manning WJ. In vivo magnetic resonance imaging of experimental thrombosis in a rabbit model. Arterioscler Thromb Vasc Biol. 2001 Sep; 21(9):1556-60. PMID: 11557688; PMCID: PMC2909772

McMahon KA, Wilson NJ, Marks DC, Beecroft TL, Whitty GA, Hamilton JA, Csar XF. Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity. Biochem J. 2001 Sep 1; 358(Pt 2):431-6. PMID: 11513742; PMCID: PMC1222076

Hamilton JA, Benson MD. Transthyretin: a review from a structural perspective. Cell Mol Life Sci. 2001 Sep; 58(10):1491-521. PMID: 11693529

Yang YH, Carmeliet P, Hamilton JA. Tissue-type plasminogen activator deficiency exacerbates arthritis. J Immunol. 2001 Jul 15; 167(2):1047-52. PMID: 11441114

Hamilton JA, Johnson RA, Corkey B, Kamp F. Fatty acid transport: the diffusion mechanism in model and biological membranes. J Mol Neurosci. 2001 Apr-Jun; 16(2-3):99-108; discussion 151-7.View Related Profiles.

Corkey, Barbara
Hamilton, James

PMID: 11478390

Watkins PA, Hamilton JA, Leaf A, Spector AA, Moore SA, Anderson RE, Moser HW, Noetzel MJ, Katz R. Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases. J Mol Neurosci. 2001 Apr-Jun; 16(2-3):87-92; discussion 151-7. PMID: 11478388

Katz R, Hamilton JA, Spector AA, Moore SA, Moser HW, Noetzel MJ, Watkins PA. Brain uptake and utilization of fatty acids: recommendations for future research. J Mol Neurosci. 2001 Apr-Jun; 16(2-3):333-5. PMID: 11478387

Hamilton JA, Jessup W, Brown AJ, Whitty G. Enhancement of macrophage survival and DNA synthesis by oxidized-low-density-lipoprotein (LDL)-derived lipids and by aggregates of lightly oxidized LDL. Biochem J. 2001 Apr 1; 355(Pt 1):207-14. PMID: 11256965; PMCID: PMC1221728

Caserta F, Tchkonia T, Civelek VN, Prentki M, Brown NF, McGarry JD, Forse RA, Corkey BE, Hamilton JA, Kirkland JL. Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes. Am J Physiol Endocrinol Metab. 2001 Feb; 280(2):E238-47.View Related Profiles.

Corkey, Barbara
Hamilton, James

PMID: 11158926

Ek-Von Mentzer BA, Zhang F, Hamilton JA. Binding of 13-HODE and 15-HETE to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins. implications for transmembrane and intracellular transport and for protection from lipid peroxidation. J Biol Chem. 2001 May 11; 276(19):15575-80. PMID: 11278949

Yaney GC, Civelek VN, Richard AM, Dillon JS, Deeney JT, Hamilton JA, Korchak HM, Tornheim K, Corkey BE, Boyd AE. Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT). Diabetes. 2001 Jan; 50(1):56-62.View Related Profiles.

Corkey, Barbara
Hamilton, James
Deeney, Jude
Tornheim, Keith

PMID: 11147795

Peng S, Guo W, Morrisett JD, Johnstone MT, Hamilton JA. Quantification of cholesteryl esters in human and rabbit atherosclerotic plaques by magic-angle spinning (13)C-NMR. Arterioscler Thromb Vasc Biol. 2000 Dec; 20(12):2682-8. PMID: 11116072

Hamilton JA, Whitty G, Jessup W. Oxidized LDL can promote human monocyte survival. Arterioscler Thromb Vasc Biol. 2000 Oct; 20(10):2329-31. PMID: 11031223

Guo W, Choi JK, Kirkland JL, Corkey BE, Hamilton JA. Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate. Biochem J. 2000 Jul 15; 349(Pt 2):463-71.View Related Profiles.

Corkey, Barbara
Hamilton, James

PMID: 10880345; PMCID: PMC1221169

Guo W, Morrisett JD, DeBakey ME, Lawrie GM, Hamilton JA. Quantification in situ of crystalline cholesterol and calcium phosphate hydroxyapatite in human atherosclerotic plaques by solid-state magic angle spinning NMR. Arterioscler Thromb Vasc Biol. 2000 Jun; 20(6):1630-6. PMID: 10845882; PMCID: PMC2933737

Lücke C, Zhang F, Hamilton JA, Sacchettini JC, Rüterjans H. Solution structure of ileal lipid binding protein in complex with glycocholate. Eur J Biochem. 2000 May; 267(10):2929-38. PMID: 10806391

Hamilton JA, Kamp F. How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids? Diabetes. 1999 Dec; 48(12):2255-69. PMID: 10580412

Guo W, Choi JK, Kirkland JL, Corkey BE, Hamilton JA. Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells. Lipids. 1999 Aug; 34(8):825-31.View Related Profiles.

Corkey, Barbara
Hamilton, James

PMID: 10529093

Hamilton JA. Transport of fatty acids across membranes by the diffusion mechanism. Prostaglandins Leukot Essent Fatty Acids. 1999 May-Jun; 60(5-6):291-7. PMID: 10471111

Lücke C, Fushman D, Ludwig C, Hamilton JA, Sacchettini JC, Rüterjans H. A comparative study of the backbone dynamics of two closely related lipid binding proteins: bovine heart fatty acid binding protein and porcine ileal lipid binding protein. Mol Cell Biochem. 1999 Feb; 192(1-2):109-21. PMID: 10331665

Guo W, Kirkland JL, Corkey B, Hamilton JA. A 13C nuclear magnetic resonance study of free fatty acid incorporation in acylated lipids in differentiating preadipocytes. Lipids. 1998 May; 33(5):449-54.View Related Profiles.

Corkey, Barbara
Hamilton, James

PMID: 9625591

Hamilton JA. Fatty acid transport: difficult or easy? J Lipid Res. 1998 Mar; 39(3):467-81. PMID: 9548581

Guo W, Morrisett JD, Lawrie GM, DeBakey ME, Hamilton JA. Identification of different lipid phases and calcium phosphate deposits in human carotid artery plaques by MAS NMR spectroscopy. Magn Reson Med. 1998 Feb; 39(2):184-9. PMID: 9469700

Vadiveloo PK, Filonzi EL, Stanton HR, Hamilton JA. G1 phase arrest of human smooth muscle cells by heparin, IL-4 and cAMP is linked to repression of cyclin D1 and cdk2. Atherosclerosis. 1997 Aug; 133(1):61-9. PMID: 9258408

Ek BA, Cistola DP, Hamilton JA, Kaduce TL, Spector AA. Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid. Biochim Biophys Acta. 1997 May 17; 1346(1):75-85. PMID: 9187305

Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA. Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit. J Biomol NMR. 1997 Apr; 9(3):213-28. PMID: 9204553

Johnson WC, Watkins MT, Hamilton J, Baldwin D. Transcutaneous partial oxygen pressure changes following skew flap and Burgess-type below-knee amputations. Arch Surg. 1997 Mar; 132(3):261-3. PMID: 9125024

Hamilton JA. CSF-1 and cell cycle control in macrophages. Mol Reprod Dev. 1997 Jan; 46(1):19-23. PMID: 8981359

Zhang F, Kamp F, Hamilton JA. Dissociation of long and very long chain fatty acids from phospholipid bilayers. Biochemistry. 1996 Dec 17; 35(50):16055-60. PMID: 8973175

Guo W, Hamilton JA. 13C MAS NMR studies of crystalline cholesterol and lipid mixtures modeling atherosclerotic plaques. Biophys J. 1996 Nov; 71(5):2857-68. PMID: 8913623; PMCID: PMC1233772

Civelek VN, Hamilton JA, Tornheim K, Kelly KL, Corkey BE. Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin. Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19):10139-44.View Related Profiles.

Corkey, Barbara
Hamilton, James
Tornheim, Keith

PMID: 8816765; PMCID: PMC38350

Gavin AL, Hamilton JA, Hogarth PM. Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding. J Biol Chem. 1996 Jul 19; 271(29):17091-9. PMID: 8663283

Lücke C, Zhang F, Rüterjans H, Hamilton JA, Sacchettini JC. Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein. Structure. 1996 Jul 15; 4(7):785-800. PMID: 8805562

Bird DA, Laposata M, Hamilton JA. Binding of ethyl oleate to low density lipoprotein, phospholipid vesicles, and albumin: a 13C NMR study. J Lipid Res. 1996 Jul; 37(7):1449-58. PMID: 8827517

Boyle E, Small DM, Gantz D, Hamilton JA, German JB. Monoacylglycerols alter the lipid composition and molecular mobility of phosphatidylcholine bilayers: 13C NMR evidence of dynamic lipid remodeling. J Lipid Res. 1996 Apr; 37(4):764-72.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 8732776

Hamilton JA, Vural JM, Carpentier YA, Deckelbaum RJ. Incorporation of medium chain triacylglycerols into phospholipid bilayers: effect of long chain triacylglycerols, cholesterol, and cholesteryl esters. J Lipid Res. 1996 Apr; 37(4):773-82. PMID: 8732777

Salmon A, Hamilton JA. Magic-angle spinning and solution 13C nuclear magnetic resonance studies of medium- and long-chain cholesteryl esters in model bilayers. Biochemistry. 1995 Dec 12; 34(49):16065-73. PMID: 8519763

Guo W, Hamilton JA. A multinuclear solid-state NMR study of phospholipid-cholesterol interactions. Dipalmitoylphosphatidylcholine-cholesterol binary system. Biochemistry. 1995 Oct 31; 34(43):14174-84. PMID: 7578015

Kamp F, Zakim D, Zhang F, Noy N, Hamilton JA. Fatty acid flip-flop in phospholipid bilayers is extremely fast. Biochemistry. 1995 Sep 19; 34(37):11928-37. PMID: 7547929

Ho JK, Moser H, Kishimoto Y, Hamilton JA. Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy. J Clin Invest. 1995 Sep; 96(3):1455-63. PMID: 7657817; PMCID: PMC185769

Guo W, Hamilton JA. Phase behavior and crystalline structures of cholesteryl ester mixtures: a C-13 MASNMR study. Biophys J. 1995 Jun; 68(6):2376-86. PMID: 7647242; PMCID: PMC1282148

Bhamidipati SP, Hamilton JA. Interactions of lyso 1-palmitoylphosphatidylcholine with phospholipids: a 13C and 31P NMR study. Biochemistry. 1995 Apr 25; 34(16):5666-77. PMID: 7727427

Guo W, Hamilton JA. Molecular organization and motions of crystalline monoacylglycerols and diacylglycerols: a C-13 MASNMR study. Biophys J. 1995 Apr; 68(4):1383-95. PMID: 7787024; PMCID: PMC1282033

Petrou S, Ordway RW, Kirber MT, Dopico AM, Hamilton JA, Walsh JV, Singer JJ. Direct effects of fatty acids and other charged lipids on ion channel activity in smooth muscle cells. Prostaglandins Leukot Essent Fatty Acids. 1995 Feb-Mar; 52(2-3):173-8.View Related Profiles.

Hamilton, James
Kirber, Michael

PMID: 7784455

Hamilton JA, Civelek VN, Kamp F, Tornheim K, Corkey BE. Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT). J Biol Chem. 1994 Aug 19; 269(33):20852-6.View Related Profiles.

Corkey, Barbara
Hamilton, James
Tornheim, Keith

PMID: 8063701

Johnson WC, Watkins MT, Hamilton J, Baldwin D, Walker N. Pentoxifylline therapy for chronic claudication: are patients dependent on therapy? Surgery. 1994 Jun; 115(6):735-9. PMID: 8197567

Ko J, Hamilton JA, Ton-Nu HT, Schteingart CD, Hofmann AF, Small DM. Effects of side chain length on ionization behavior and transbilayer transport of unconjugated dihydroxy bile acids: a comparison of nor-chenodeoxycholic acid and chenodeoxycholic acid. J Lipid Res. 1994 May; 35(5):883-92.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 8071610

Petrou S, Ordway RW, Hamilton JA, Walsh JV, Singer JJ. Structural requirements for charged lipid molecules to directly increase or suppress K+ channel activity in smooth muscle cells. Effects of fatty acids, lysophosphatidate, acyl coenzyme A and sphingosine. J Gen Physiol. 1994 Mar; 103(3):471-86. PMID: 8195783; PMCID: PMC2216847

Kenyon MA, Hamilton JA. 13C NMR studies of the binding of medium-chain fatty acids to human serum albumin. J Lipid Res. 1994 Mar; 35(3):458-67. PMID: 8014580

Kamp F, Hamilton JA, Kamp F, Westerhoff HV, Hamilton JA. Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers. Biochemistry. 1993 Oct 19; 32(41):11074-86. PMID: 8218171

Guo W, Hamilton JA. Molecular organization and motions of cholesteryl esters in crystalline and liquid crystalline phases: a 13C and 1H magic angle spinning NMR study. Biochemistry. 1993 Sep 7; 32(35):9038-52. PMID: 8369277

Bhamidipati SP, Hamilton JA. NMR studies of phospholipase C hydrolysis of phosphatidylcholine in model membranes. J Biol Chem. 1993 Feb 5; 268(4):2431-4. PMID: 8428917

Kamp F, Hamilton JA. pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids. Proc Natl Acad Sci U S A. 1992 Dec 1; 89(23):11367-70. PMID: 1454821; PMCID: PMC50551

Elliott MJ, Faulkner-Jones BE, Stanton H, Hamilton JA, Metcalf D. Plasminogen activator in granulocyte-macrophage-CSF transgenic mice. J Immunol. 1992 Dec 1; 149(11):3678-81. PMID: 1431138

Smith SO, Kustanovich I, Bhamidipati S, Salmon A, Hamilton JA. Interfacial conformation of dipalmitoylglycerol and dipalmitoylphosphatidylcholine in phospholipid bilayers. Biochemistry. 1992 Nov 24; 31(46):11660-4. PMID: 1445903

Hamilton JA, Vairo G, Cocks BG. Inhibition of S-phase progression in macrophages is linked to G1/S-phase suppression of DNA synthesis genes. J Immunol. 1992 Jun 15; 148(12):4028-35. PMID: 1351091

Boylan JG, Hamilton JA. Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin. Biochemistry. 1992 Jan 21; 31(2):557-67. PMID: 1731912

Bhaskar KR, Gong DH, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT. Profound increase in viscosity and aggregation of pig gastric mucin at low pH. Am J Physiol. 1991 Nov; 261(5 Pt 1):G827-32.View Related Profiles.

Hamilton, James
Bansil, Rama

PMID: 1719823

Deshpande MS, Boylan J, Hamilton JA, Burton J. Conformation and inhibitory properties of peptides based on the tissue kallikrein-aprotinin complex. Int J Pept Protein Res. 1991 Jun; 37(6):536-43. PMID: 1717392

Hamilton JA, Fujito DT, Hammer CF. Solubilization and localization of weakly polar lipids in unsonicated egg phosphatidylcholine: A 13C MAS NMR study. Biochemistry. 1991 Mar 19; 30(11):2894-902. PMID: 2007127

Hamilton JA, Era S, Bhamidipati SP, Reed RG. Locations of the three primary binding sites for long-chain fatty acids on bovine serum albumin. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2051-4. PMID: 2006141; PMCID: PMC51166

Hamilton JA, Bhamidipati SP, Kodali DR, Small DM. The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers. J Biol Chem. 1991 Jan 15; 266(2):1177-86.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 1985941

Spooner PJ, Gantz DL, Hamilton JA, Small DM. The distribution of oleic acid between chylomicron-like emulsions, phospholipid bilayers, and serum albumin. A model for fatty acid distribution between lipoproteins, membranes, and albumin. J Biol Chem. 1990 Jul 25; 265(21):12650-5.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 2373706

Deckelbaum RJ, Hamilton JA, Moser A, Bengtsson-Olivecrona G, Butbul E, Carpentier YA, Gutman A, Olivecrona T. Medium-chain versus long-chain triacylglycerol emulsion hydrolysis by lipoprotein lipase and hepatic lipase: implications for the mechanisms of lipase action. Biochemistry. 1990 Feb 6; 29(5):1136-42. PMID: 2322552

Bhamidipati SP, Hamilton JA. Hydrolysis of a phospholipid in an inert lipid matrix by phospholipase A2: a 13C NMR study. Biochemistry. 1989 Aug 8; 28(16):6667-72. PMID: 2790021

Hamilton JA. Medium-chain fatty acid binding to albumin and transfer to phospholipid bilayers. Proc Natl Acad Sci U S A. 1989 Apr; 86(8):2663-7. PMID: 2704741; PMCID: PMC286978

Hamilton JA. Interactions of triglycerides with phospholipids: incorporation into the bilayer structure and formation of emulsions. Biochemistry. 1989 Mar 21; 28(6):2514-20. PMID: 2730879

Cistola DP, Hamilton JA, Jackson D, Small DM. Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule. Biochemistry. 1988 Mar 22; 27(6):1881-8.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3378036

Cistola DP, Walsh MT, Corey RP, Hamilton JA, Brecher P. Interactions of oleic acid with liver fatty acid binding protein: a carbon-13 NMR study. Biochemistry. 1988 Jan 26; 27(2):711-7.View Related Profiles.

Hamilton, James
Brecher, Peter

PMID: 3349060

Spooner PJ, Clark SB, Gantz DL, Hamilton JA, Small DM. The ionization and distribution behavior of oleic acid in chylomicrons and chylomicron-like emulsion particles and the influence of serum albumin. J Biol Chem. 1988 Jan 25; 263(3):1444-53.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3335552

Walsh MT, Hamilton JA, Atkinson D, Small DM. Secondary and tertiary structure of apolipoproteins. Adv Exp Med Biol. 1988; 243:123-32.View Related Profiles.

Atkinson, David
Small, Donald
Hamilton, James

PMID: 3066173

Croll DH, Sripada PK, Hamilton JA. Temperature-dependent molecular motions and phase behavior of cholesteryl ester analogues. J Lipid Res. 1987 Dec; 28(12):1444-54. PMID: 3430070

Cistola DP, Small DM, Hamilton JA. Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites. J Biol Chem. 1987 Aug 15; 262(23):10980-5.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3611100

Cistola DP, Small DM, Hamilton JA. Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites. J Biol Chem. 1987 Aug 15; 262(23):10971-9.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3611099

Sripada PK, Maulik PR, Hamilton JA, Shipley GG. Partial synthesis and properties of a series of N-acyl sphingomyelins. J Lipid Res. 1987 Jun; 28(6):710-8.View Related Profiles.

Shipley, G.
Hamilton, James

PMID: 3611973

Cabral DJ, Small DM, Lilly HS, Hamilton JA. Transbilayer movement of bile acids in model membranes. Biochemistry. 1987 Apr 7; 26(7):1801-4.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3593691

Spooner PJ, Hamilton JA, Gantz DL, Small DM. The effect of free cholesterol on the solubilization of cholesteryl oleate in phosphatidylcholine bilayers: A 13C-NMR study. Biochim Biophys Acta. 1986 Aug 21; 860(2):345-53.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3741856

Cistola DP, Atkinson D, Hamilton JA, Small DM. Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps. Biochemistry. 1986 May 20; 25(10):2804-12.View Related Profiles.

Atkinson, David
Small, Donald
Hamilton, James

PMID: 3718922

Cabral DJ, Hamilton JA, Small DM. The ionization behavior of bile acids in different aqueous environments. J Lipid Res. 1986 Mar; 27(3):334-43.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 3734630

Hamilton JA, Morrisett JD. Nuclear magnetic resonance studies of lipoproteins. Methods Enzymol. 1986; 128:472-515. PMID: 3724520

Hamilton JA, Cistola DP. Transfer of oleic acid between albumin and phospholipid vesicles. Proc Natl Acad Sci U S A. 1986 Jan; 83(1):82-6. PMID: 3455761; PMCID: PMC322795

Croll DH, Small DM, Hamilton JA. Molecular motions and thermotropic phase behavior of cholesteryl esters with triolein. Biochemistry. 1985 Dec 31; 24(27):7971-80.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 4092048

Morrisett JD, Gaubatz JW, Tarver AP, Allen JK, Pownall HJ, Laggner P, Hamilton JA. Thermotropic properties and molecular dynamics of cholesteryl ester rich very low density lipoproteins: effect of hydrophobic core on polar surface. Biochemistry. 1984 Oct 23; 23(22):5343-52. PMID: 6095895

Small DM, Cabral DJ, Cistola DP, Parks JS, Hamilton JA. The ionization behavior of fatty acids and bile acids in micelles and membranes. Hepatology. 1984 Sep-Oct; 4(5 Suppl):77S-79S.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 6479889

Hamilton JA, Cistola DP, Morrisett JD, Sparrow JT, Small DM. Interactions of myristic acid with bovine serum albumin: a 13C NMR study. Proc Natl Acad Sci U S A. 1984 Jun; 81(12):3718-22.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 6587386; PMCID: PMC345290

Hamilton JA, Miller KW, Small DM. Solubilization of triolein and cholesteryl oleate in egg phosphatidylcholine vesicles. J Biol Chem. 1983 Nov 10; 258(21):12821-6.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 6685124

Parks JS, Cistola DP, Small DM, Hamilton JA. Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study. J Biol Chem. 1983 Aug 10; 258(15):9262-9.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 6874688

Hamilton JA, Small DM, Parks JS. 1H NMR studies of lymph chylomicra and very low density lipoproteins from nonhuman primates. J Biol Chem. 1983 Jan 25; 258(2):1172-9.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 6822495

Ginsburg GS, Small DM, Hamilton JA. Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study. Biochemistry. 1982 Dec 21; 21(26):6857-67.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 7159569

Hamilton JA, Small DM. Solubilization and localization of cholesteryl oleate in egg phosphatidylcholine vesicles. A carbon 13 NMR study. J Biol Chem. 1982 Jul 10; 257(13):7318-21.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 7200981

Cistola DP, Small DM, Hamilton JA. Ionization behavior of aqueous short-chain carboxylic acids: a carbon-13 NMR study. J Lipid Res. 1982 Jul; 23(5):795-9.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 7119577

Hamilton JA, Zabriskie JB, Lachman LB, Chen YS. Streptococcal cell walls and synovial cell activation. Stimulation of synovial fibroblast plasminogen activator activity by monocytes treated with group A streptococcal cell wall sonicates and muramyl dipeptide. J Exp Med. 1982 Jun 1; 155(6):1702-18. PMID: 6804590; PMCID: PMC2186715

Clark SB, Atkinson D, Hamilton JA, Forte T, Russell B, Feldman EB, Small DM. Physical studies of d less than 1.006 g/ml lymph lipoproteins from rats fed palmitate-rich diets. J Lipid Res. 1982 Jan; 23(1):28-41.View Related Profiles.

Atkinson, David
Small, Donald
Hamilton, James

PMID: 7057111

Hamilton JA, Small DM. Solubilization and localization of triolein in phosphatidylcholine bilayers: a 13C NMR study. Proc Natl Acad Sci U S A. 1981 Nov; 78(11):6878-82.View Related Profiles.

Small, Donald
Hamilton, James

PMID: 6947263; PMCID: PMC349155

Brainard JR, Hamilton JA, Cordes EH, Patsch JR, Gotto AM, Morrisett JD. Lipoprotein-X: carbon-13 nuclear magnetic resonance studies on native, reconstituted, and model systems. Biochemistry. 1980 Sep 2; 19(18):4266-73. PMID: 7417403

Hamilton JA, Cordes EH, Glueck CJ. Lipid dynamics in human low density lipoproteins and human aortic tissue with fibrous plaques. A study by high field 13C NMR spectroscopy. J Biol Chem. 1979 Jun 25; 254(12):5435-41. PMID: 221471

Hamilton JA, Cordes EH. Molecular dynamics of lipids in human plasma high density lipoproteins. A high field 13C NMR study. J Biol Chem. 1978 Jul 25; 253(14):5193-8. PMID: 209030

Avila EM, Hamilton JA, Harmony JA, Allerhand A, Cordes EH. Natural abundance 13C nuclear magnetic resonance studies of human plasma high density lipoproteins. J Biol Chem. 1978 Jun 10; 253(11):3983-7. PMID: 206556

Hamilton JA, Oppenheimer N, Cordes EH. Carbon-13 nuclear magnetic resonance studies of cholesteryl esters and cholesteryl ester/triglyceride mixtures. J Biol Chem. 1977 Nov 25; 252(22):8071-80. PMID: 914864

Avila-Bello EM, Hamilton JA, Talkowski C, Harmony JA, Allerhand A, Cordes EH, Camejo G. [Structure of plasma lipoproteins (author's transl)]. Acta Cient Venez. 1977; 28(1):37-43. PMID: 865775

Hamilton JA, Oppenheimer NJ, Addleman R, Clouse AO, Cordes EH, Steiner PM, Glueck CJ. High-field 13C NMR Studies of certain normal and abnormal human plasma lipoproteins. Science. 1976 Dec 24; 194(4272):1424-7. PMID: 188128

Hamilton JA, Miller JF. Hapten-specific tolerance in mice. I. Induction with hapten-coupled syngeneic erythrocytes. Eur J Immunol. 1974 Apr; 4(4):261-8. PMID: 4604520

Hamilton JA, Miller JF. Induction of a primary antihapten response in vivo by a graft-vs.-host reaction. J Exp Med. 1973 Oct 1; 138(4):1009-14. PMID: 4147578; PMCID: PMC2180566

Williams E, Hamilton JA, Jain MK, Allerhand A, Cordes EH, Ochs S. Natural abundance carbon-13 nuclear magnetic resonance spectra of the canine sciatic nerve. Science. 1973 Aug 31; 181(4102):869-71. PMID: 4724077

Hamilton JA, Miller JF. Hapten-specific tolerance: unresponsiveness in the T cell-depleted population. Eur J Immunol. 1973 Jul; 3(7):457-60. PMID: 4586172

Hamilton JA, Talkowski C, Williams E, Avila EM, Allerhand A, Cordes EH, Camejo G. Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum lipoproteins. Science. 1973 Apr 15; 180(4082):193-5. PMID: 4348464

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 214 publications over 43 distinct years, with a maximum of 15 publications in 2007

Bar chart showing 214 publications over 43 distinct years, with a maximum of 15 publications in 2007

Year	Publications
1980	1
1981	1
1982	5
1983	3
1984	3
1985	1
1986	5
1987	5
1988	4
1989	3
1990	2
1991	5
1992	5
1993	3
1994	5
1995	8
1996	8
1997	5
1998	3
1999	4
2000	5
2001	11
2002	6
2003	8
2004	5
2005	5
2006	7
2007	15
2008	7
2009	8
2010	6
2011	5
2012	4
2013	9
2014	6
2015	6
2016	3
2017	6
2018	7
2019	1
2020	3
2021	1
2022	1

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In addition to these self-described keywords below, a list of MeSH based concepts is available here.

heart disease
diabetes
obesity
fatty acid
metabolism

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