Irina N. Gorshkova, PhD
Senior Research Scientist
Boston University School of Medicine
Dept of Physiology & Biophysics
Cardiovascular Medicine

PhD, National Cardiology Research Center
MS, Moscow State University

1994-1996 Russian Government Program on Atherosclerosis: Investigator Award
1994 International Atherosclerosis Society: Visiting Fellowship Award
1993 The Deutsche Forschungsgemeinschaft : Fellowship Award

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Gorshkova IN, Mei X, Atkinson D. Arginine 123 of apolipoprotein A-I is essential for lecithin:cholesterol acyltransferase activity. J Lipid Res. 2018 02; 59(2):348-356.View Related Profiles. PMID: 29208698; PMCID: PMC5794428; DOI: 10.1194/jlr.M080986;
  2. Gorshkova IN, Atkinson D. Increased Binding of Apolipoproteins A-I and E4 to Triglyceride-Rich Lipoproteins is linked to Induction of Hypertriglyceridemia. JSM Atheroscler. 2017; 2(2).View Related Profiles. PMID: 28597004; PMCID: PMC5460632
  3. Gorshkova IN, Mei X, Atkinson D. Binding of human apoA-I[K107del] variant to TG-rich particles: implications for mechanisms underlying hypertriglyceridemia. J Lipid Res. 2014 Sep; 55(9):1876-85.View Related Profiles. PMID: 24919401; PMCID: PMC4617355; DOI: 10.1194/jlr.M047241;
  4. Kateifides AK, Gorshkova IN, Duka A, Chroni A, Kardassis D, Zannis VI. Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL. J Lipid Res. 2011 Jul; 52(7):1363-72.View Related Profiles. PMID: 21504968; PMCID: PMC3122915; DOI: 10.1194/jlr.M012989;
  5. Gorshkova IN, Atkinson D. Enhanced binding of apolipoprotein A-I variants associated with hypertriglyceridemia to triglyceride-rich particles. Biochemistry. 2011 Mar 29; 50(12):2040-7.View Related Profiles. PMID: 21288012; PMCID: PMC6128146; DOI: 10.1021/bi200158b;
  6. Gorshkova IN, Kypreos KE, Gantz DL, Zannis VI, Atkinson D. Biophysical properties of apolipoprotein E4 variants: implications in molecular mechanisms of correction of hypertriglyceridemia. Biochemistry. 2008 Nov 25; 47(47):12644-54.View Related Profiles. PMID: 18959431; PMCID: PMC2748909; DOI: 10.1021/bi8015857;
  7. Gorshkova IN, Liu T, Kan HY, Chroni A, Zannis VI, Atkinson D. Structure and stability of apolipoprotein a-I in solution and in discoidal high-density lipoprotein probed by double charge ablation and deletion mutation. Biochemistry. 2006 Jan 31; 45(4):1242-54.View Related Profiles. PMID: 16430220; PMCID: PMC2532493; DOI: 10.1021/bi051669r;
  8. Chroni A, Kan HY, Kypreos KE, Gorshkova IN, Shkodrani A, Zannis VI. Substitutions of glutamate 110 and 111 in the middle helix 4 of human apolipoprotein A-I (apoA-I) by alanine affect the structure and in vitro functions of apoA-I and induce severe hypertriglyceridemia in apoA-I-deficient mice. Biochemistry. 2004 Aug 17; 43(32):10442-57.View Related Profiles. PMID: 15301543
  9. Chroni A, Liu T, Gorshkova I, Kan HY, Uehara Y, Von Eckardstein A, Zannis VI. The central helices of ApoA-I can promote ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-type ApoA-I are required for lipid efflux in vitro and high density lipoprotein formation in vivo. J Biol Chem. 2003 Feb 28; 278(9):6719-30.View Related Profiles. PMID: 12488454
  10. Gorshkova IN, Liu T, Zannis VI, Atkinson D. Lipid-free structure and stability of apolipoprotein A-I: probing the central region by mutation. Biochemistry. 2002 Aug 20; 41(33):10529-39.View Related Profiles. PMID: 12173940
Showing 10 of 30 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 29 publications over 18 distinct years, with a maximum of 3 publications in 1983 and 1990


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

biophysical methods
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700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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