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PhD, Massachusetts Institute of Technology






Title


Yr Title Project-Sub Proj Pubs
2023 Development of a Companion Diagnostic Assay for Detection of ADAM8-Positive Cancers 5R44CA275462-02
2019 Development of a Companion Diagnostic Assay for Detection of ADAM8-Positive Cancers 1R43CA239942-01
2019 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 5R44CA200161-03
2019 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 3R44CA200161-03S1
2018 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 2R44CA200161-02A1
2018 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 3R41CA200161-01A1S3
2017 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 3R41CA200161-01A1S2
2017 ADAM8 Is a Novel Target for Treatment of Triple-Negative Breast Cancer 5R21CA194955-02
2016 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 3R41CA200161-01A1S1
2016 Antibody targeting of ADAM8 for treatment of triple-negative breast cancer 1R41CA200161-01A1
Showing 10 of 88 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Romagnoli M, Mineva ND, Polmear M, Conrad C, Srinivasan S, Loussouarn D, Barillé-Nion S, Georgakoudi I, Dagg Á, McDermott EW, Duffy MJ, McGowan PM, Schlomann U, Parsons M, Bartsch JW, Sonenshein GE. ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis. EMBO Mol Med. 2014 Feb; 6(2):278-94. PMID: 24375628; PMCID: PMC3927960; DOI: 10.1002/emmm.201303373;
     
  2. Sato S, Zhao Y, Imai M, Simister PC, Feller SM, Trackman PC, Kirsch KH, Sonenshein GE. Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. PLoS One. 2013; 8(10):e77288.View Related Profiles. PMID: 24167568; PMCID: PMC3805583; DOI: 10.1371/journal.pone.0077288;
     
  3. Mineva ND, Paulson KE, Naber SP, Yee AS, Sonenshein GE. Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells. PLoS One. 2013; 8(9):e73464. PMID: 24039951; PMCID: PMC3770659; DOI: 10.1371/journal.pone.0073464;
     
  4. Romagnoli M, Belguise K, Yu Z, Wang X, Landesman-Bollag E, Seldin DC, Chalbos D, Barillé-Nion S, Jézéquel P, Seldin ML, Sonenshein GE. Epithelial-to-mesenchymal transition induced by TGF-ß1 is mediated by Blimp-1-dependent repression of BMP-5. Cancer Res. 2012 Dec 1; 72(23):6268-78.View Related Profiles. PMID: 23054396; PMCID: PMC3513653; DOI: 10.1158/0008-5472.CAN-12-2270;
     
  5. Yu Z, Sato S, Trackman PC, Kirsch KH, Sonenshein GE. Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide. PLoS One. 2012; 7(3):e33287.View Related Profiles. PMID: 22438909; PMCID: PMC3305320; DOI: 10.1371/journal.pone.0033287;
     
  6. Bais MV, Nugent MA, Stephens DN, Sume SS, Kirsch KH, Sonenshein GE, Trackman PC. Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts. PLoS One. 2012; 7(2):e31188.View Related Profiles. PMID: 22363577; PMCID: PMC3280126; DOI: 10.1371/journal.pone.0031188;
     
  7. Sánchez-Morgan N, Kirsch KH, Trackman PC, Sonenshein GE. The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits ß-catenin transcriptional activity in lung cancer cells. Mol Cell Biol. 2011 Aug; 31(16):3286-97.View Related Profiles. PMID: 21690299; PMCID: PMC3147807; DOI: 10.1128/MCB.01426-10;
     
  8. Sato S, Trackman PC, Mäki JM, Myllyharju J, Kirsch KH, Sonenshein GE. The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. Mol Cell Biol. 2011 Jul; 31(13):2683-95.View Related Profiles. PMID: 21536655; PMCID: PMC3133379; DOI: 10.1128/MCB.01148-10;
     
  9. Min C, Zhao Y, Romagnoli M, Trackman PC, Sonenshein GE, Kirsch KH. Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis. J Cell Biochem. 2010 Dec 1; 111(5):1160-8.View Related Profiles. PMID: 20717927; PMCID: PMC3907072; DOI: 10.1002/jcb.22828;
     
  10. Vora SR, Guo Y, Stephens DN, Salih E, Vu ED, Kirsch KH, Sonenshein GE, Trackman PC. Characterization of recombinant lysyl oxidase propeptide. Biochemistry. 2010 Apr 6; 49(13):2962-72.View Related Profiles. PMID: 20192271; PMCID: PMC2847845; DOI: 10.1021/bi902218p;
     
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