Dennis Jones | Profiles RNS

Dennis Jones, PhD

Assistant Professor

Boston University School of Medicine

Pathology & Laboratory Medicine

PhD, Yale University School of Medicine

Websites

	LinkedIn
	Jones Laboratory
	Immunology Training Program Faculty
	ORCID
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Dennis Jones, PhD is an Assistant Professor of Pathology & Laboratory Medicine at the Boston University School of Medicine. The current focus of the Jones laboratory is delineating the immune evasion mechanisms used by cancer cells to persist in lymph nodes and eventually metastasize to distant organs. The goal of the Jones laboratory is to identify strategies and molecular targets to stop the growth of metastases by enhancing anti-tumor immunity.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Member
Boston University
BU-BMC Cancer Center

2018 Gordon Research Conference (Lymphatics) Poster Award

2018 Massachusetts General Hospital Outstanding Research Award

2018 NIH Transition Career Development Award (K22)

2017 NIH Future Research Leader

2017 Massachusetts Institute of Technology Rising Star in Biomedical

2015 NIH National Research Service Award (F32) Postdoctoral Fellow

2014 UNCF-Merck Postdoctoral Fellow

2014 Burroughs Wellcome Fund Postdoctoral Enrichment Program Fellow

2012 NIH Institutional Training Grant (T32) Fellow

2008 NIH National Research Service Award (F31) Predoctoral Fellow

2007 Anna Fuller Fellow

2005 Achievement Rewards for College Scientists (ARCS) Scholar

2004 Minority Biomedical Research Support (MBRS) Fellow

BU Research

Understanding the mechanisms of immune suppression in lymph node metastases
09/30/2018 - 08/31/2021 (PI)
NIH/National Cancer Institute
5K22CA230315-02

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Jones D. Parallels of Resistance between Angiogenesis and Lymphangiogenesis Inhibition in Cancer Therapy. Cells. 2020 Mar 20; 9(3). PMID: 32244922

Liu T, Li Y, Su H, Zhang H, Jones D, Zhou HJ, Ji W, Min W. Nuclear localization of the tyrosine kinase BMX mediates VEGFR2 expression. J Cell Mol Med. 2020 01; 24(1):126-138. PMID: 31642192; DOI: 10.1111/jcmm.14663;

Zhao Y, Cao J, Melamed A, Worley M, Gockley A, Jones D, Nia HT, Zhang Y, Stylianopoulos T, Kumar AS, Mpekris F, Datta M, Sun Y, Wu L, Gao X, Yeku O, Del Carmen MG, Spriggs DR, Jain RK, Xu L. Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma. Proc Natl Acad Sci U S A. 2019 02 05; 116(6):2210-2219. PMID: 30659155; DOI: 10.1073/pnas.1818357116;

Liao S, Bouta EM, Morris LM, Jones D, Jain RK, Padera TP. Inducible Nitric Oxide Synthase and CD11b+Gr1+ Cells Impair Lymphatic Contraction of Tumor-Draining Lymphatic Vessels. Lymphat Res Biol. 2019 06; 17(3):294-300. PMID: 30358484; DOI: 10.1089/lrb.2018.0013;

Pereira ER, Kedrin D, Seano G, Gautier O, Meijer EFJ, Jones D, Chin SM, Kitahara S, Bouta EM, Chang J, Beech E, Jeong HS, Carroll MC, Taghian AG, Padera TP. Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice. Science. 2018 03 23; 359(6382):1403-1407. PMID: 29567713; DOI: 10.1126/science.aal3622;

Jones D, Pereira ER, Padera TP. Growth and Immune Evasion of Lymph Node Metastasis. Front Oncol. 2018; 8:36. PMID: 29527513; DOI: 10.3389/fonc.2018.00036;

Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP. Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction. Sci Transl Med. 2018 01 17; 10(424). PMID: 29343625; DOI: 10.1126/scitranslmed.aam7964;

Meijer EFJ, Blatter C, Chen IX, Bouta E, Jones D, Pereira ER, Jung K, Vakoc BJ, Baish JW, Padera TP. Lymph node effective vascular permeability and chemotherapy uptake. Microcirculation. 2017 08; 24(6). PMID: 28510992; DOI: 10.1111/micc.12381;

Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, Grodzinsky AJ, Baish JW, Munn LL, Jain RK. Solid stress and elastic energy as measures of tumour mechanopathology. Nat Biomed Eng. 2016; 1. PMID: 28966873; DOI: 10.1038/s41551-016-0004;

Blatter C, Meijer EF, Nam AS, Jones D, Bouma BE, Padera TP, Vakoc BJ. In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography. Sci Rep. 2016 07 05; 6:29035. PMID: 27377852; DOI: 10.1038/srep29035;

Showing 10 of 22 results. Show More

Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP. Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. J Natl Cancer Inst. 2015 Sep; 107(9). PMID: 26063793; DOI: 10.1093/jnci/djv155;

Pereira ER, Jones D, Jung K, Padera TP. The lymph node microenvironment and its role in the progression of metastatic cancer. Semin Cell Dev Biol. 2015 Feb; 38:98-105. PMID: 25620792; DOI: 10.1016/j.semcdb.2015.01.008;

Liao S, Jones D, Cheng G, Padera TP. Method for the quantitative measurement of collecting lymphatic vessel contraction in mice. J Biol Methods. 2014; 1(2). PMID: 25512945; DOI: 10.14440/jbm.2014.26;

Holopainen T, López-Alpuche V, Zheng W, Heljasvaara R, Jones D, He Y, Tvorogov D, D'Amico G, Wiener Z, Andersson LC, Pihlajaniemi T, Min W, Alitalo K. Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth. Cancer Res. 2012 Jul 15; 72(14):3512-21. PMID: 22593188; DOI: 10.1158/0008-5472.CAN-11-1070;

Truman LA, Bentley KL, Smith EC, Massaro SA, Gonzalez DG, Haberman AM, Hill M, Jones D, Min W, Krause DS, Ruddle NH. ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets. Am J Pathol. 2012 Apr; 180(4):1715-25. PMID: 22310467; DOI: 10.1016/j.ajpath.2011.12.026;

Jones D, Li Y, He Y, Xu Z, Chen H, Min W. Mirtron microRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2012 Mar; 32(3):633-42. PMID: 22223733; DOI: 10.1161/ATVBAHA.111.243576;

Jones D, Min W. An overview of lymphatic vessels and their emerging role in cardiovascular disease. J Cardiovasc Dis Res. 2011 Jul; 2(3):141-52. PMID: 22022141; DOI: 10.4103/0975-3583.85260;

Jones D. Genetic engineering of a mouse: Dr. Frank Ruddle and somatic cell genetics. Yale J Biol Med. 2011 Jun; 84(2):117-24. PMID: 21698043

Jones D, Xu Z, Zhang H, He Y, Kluger MS, Chen H, Min W. Functional analyses of the bone marrow kinase in the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2553-61. PMID: 20864667; DOI: 10.1161/ATVBAHA.110.214999;

Luo Y, Xu Z, Wan T, He Y, Jones D, Zhang H, Min W. Endothelial-specific transgenesis of TNFR2 promotes adaptive arteriogenesis and angiogenesis. Arterioscler Thromb Vasc Biol. 2010 Jul; 30(7):1307-14. PMID: 20395596; DOI: 10.1161/ATVBAHA.110.204222;

Dai S, He Y, Zhang H, Yu L, Wan T, Xu Z, Jones D, Chen H, Min W. Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis. Arterioscler Thromb Vasc Biol. 2009 Apr; 29(4):495-502. PMID: 19150880; DOI: 10.1161/ATVBAHA.108.180349;

Zhang H, He Y, Dai S, Xu Z, Luo Y, Wan T, Luo D, Jones D, Tang S, Chen H, Sessa WC, Min W. AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice. J Clin Invest. 2008 Dec; 118(12):3904-16. PMID: 19033661; DOI: 10.1172/JCI36168;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 22 publications over 12 distinct years, with a maximum of 4 publications in 2018